Experiment set3IT085 for Pseudomonas fluorescens GW456-L13

Compare to:

D-Serine nitrogen source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_3934 -6.8 -4.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_2103 -6.2 -4.3 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_3948 -6.2 -4.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_4031 -6.1 -3.8 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
PfGW456L13_1222 -6.0 -4.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_3940 -6.0 -5.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_362 -6.0 -5.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_1472 -5.9 -4.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_644 -5.8 -6.8 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_3947 -5.7 -3.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1007 -5.6 -7.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_727 -5.6 -10.0 LysR family transcriptional regulator PA5437 compare
PfGW456L13_1368 -5.5 -3.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_347 -5.5 -8.4 Nitrogen regulation protein NR(I) compare
PfGW456L13_1150 -5.4 -11.6 Biotin synthesis protein BioC compare
PfGW456L13_1540 -5.4 -9.1 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_2046 -5.4 -5.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_1539 -5.3 -7.3 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_5000 -5.3 -13.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_5001 -5.3 -9.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_1010 -5.3 -7.2 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_3945 -5.2 -10.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_728 -5.2 -12.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_973 -5.2 -11.2 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_1221 -5.2 -17.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_951 -5.2 -11.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_1205 -5.2 -7.1 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_272 -5.2 -26.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_1148 -5.1 -15.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_1151 -5.1 -9.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_2842 -5.1 -6.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_149 -5.0 -7.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_1147 -5.0 -12.9 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_3647 -4.9 -17.7 D-serine dehydratase transcriptional activator conserved
PfGW456L13_949 -4.9 -11.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_1217 -4.9 -19.4 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_359 -4.8 -9.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_1235 -4.8 -10.3 Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-) compare
PfGW456L13_2230 -4.8 -10.6 Cys regulon transcriptional activator CysB compare
PfGW456L13_271 -4.8 -17.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_172 -4.8 -9.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_4009 -4.8 -15.6 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_1204 -4.8 -10.6 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases compare
PfGW456L13_1538 -4.8 -6.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1233 -4.8 -3.3 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1050 -4.7 -7.9 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_3648 -4.7 -16.4 D-serine ammonia-lyase (EC 4.3.1.18) (from data) conserved
PfGW456L13_361 -4.7 -12.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_2656 -4.7 -7.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_845 -4.7 -4.6 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_913 -4.6 -6.3 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_779 -4.6 -13.4 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_3960 -4.5 -11.1 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_2843 -4.5 -10.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_1739 -4.5 -11.2 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_565 -4.5 -6.1 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_2957 -4.4 -7.3 Sensory histidine kinase QseC compare
PfGW456L13_140 -4.4 -5.2 FIG003573: hypothetical protein compare
PfGW456L13_2032 -4.4 -5.2 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_1142 -4.4 -11.9 Protein rarD conserved
PfGW456L13_854 -4.3 -3.0 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_4999 -4.3 -12.4 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_2176 -4.3 -6.9 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_282 -4.3 -14.1 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
PfGW456L13_4088 -4.2 -4.1 Transcriptional regulator, GntR family compare
PfGW456L13_953 -4.2 -14.5 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_1615 -4.2 -2.2 Probable transmembrane protein compare
PfGW456L13_1044 -4.2 -12.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_1749 -4.2 -4.9 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_4854 -4.2 -13.0 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_1006 -4.1 -6.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_4645 -4.1 -18.8 AmpG permease compare
PfGW456L13_729 -4.1 -11.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_358 -4.0 -3.1 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_302 -4.0 -5.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_4125 -4.0 -2.7 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_2237 -4.0 -2.7 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_1973 -3.9 -5.9 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_303 -3.9 -2.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_757 -3.8 -3.2 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_2170 -3.7 -5.0 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
PfGW456L13_5067 -3.7 -11.2 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_5017 -3.7 -5.6 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_1553 -3.7 -10.5 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_274 -3.7 -13.0 DamX, an inner membrane protein involved in bile resistance compare
PfGW456L13_1863 -3.7 -9.3 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_656 -3.6 -3.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_276 -3.6 -1.9 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_3894 -3.5 -2.6 Integration host factor alpha subunit compare
PfGW456L13_2956 -3.5 -6.6 Transcriptional regulatory protein RstA compare
PfGW456L13_566 -3.4 -8.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_1889 -3.4 -3.3 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_1972 -3.4 -3.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_793 -3.4 -3.3 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_275 -3.4 -2.3 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_50 -3.3 -9.7 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_787 -3.3 -10.8 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_4165 -3.3 -5.0 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_4012 -3.2 -2.2 VacJ-like lipoprotein precursor compare
PfGW456L13_2035 -3.2 -13.7 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_2552 -3.2 -8.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1520 -3.2 -5.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
PfGW456L13_1981 -3.1 -8.0 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_1391 -3.1 -3.0 Transcriptional regulator, AsnC family compare
PfGW456L13_1220 -3.0 -6.0 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1860 -3.0 -6.7 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
PfGW456L13_4037 -3.0 -4.5 FIG00953287: hypothetical protein compare
PfGW456L13_1901 -2.9 -7.9 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_4859 -2.9 -4.4 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_892 -2.9 -10.3 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
PfGW456L13_1606 -2.8 -12.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_751 -2.8 -5.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
PfGW456L13_2553 -2.8 -10.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_5003 -2.7 -2.7 YrbA protein compare
PfGW456L13_360 -2.7 -3.4 FIG00956267: hypothetical protein compare
PfGW456L13_943 -2.6 -5.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_2632 -2.6 -4.4 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_144 -2.5 -6.2 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_4711 -2.4 -15.5 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_932 -2.4 -6.4 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
PfGW456L13_1363 -2.3 -5.5 Rare lipoprotein A precursor compare
PfGW456L13_1845 -2.3 -3.7 Cold shock protein CspC compare
PfGW456L13_1735 -2.3 -4.0 Glycerol uptake facilitator protein compare
PfGW456L13_150 -2.3 -1.6 hypothetical protein compare
PfGW456L13_2631 -2.3 -3.8 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_4451 -2.2 -6.2 ATP-dependent RNA helicase SrmB compare
PfGW456L13_874 -2.2 -14.6 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_403 -2.2 -4.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
PfGW456L13_1642 -2.2 -7.2 LppC putative lipoprotein compare
PfGW456L13_1011 -2.2 -1.9 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_1284 -2.2 -2.8 Putative transport protein compare
PfGW456L13_1842 -2.2 -9.7 Outer membrane porin, OprD family compare
PfGW456L13_952 -2.2 -4.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_2623 -2.1 -2.7 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_928 -2.1 -7.1 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
PfGW456L13_4517 -2.1 -11.4 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_1236 -2.0 -8.5 Cell wall endopeptidase, family M23/M37 compare
PfGW456L13_5018 -2.0 -5.7 Phosphocarrier protein, nitrogen regulation associated compare
PfGW456L13_742 -2.0 -3.4 Aspartate ammonia-lyase (EC 4.3.1.1) compare
PfGW456L13_4599 -1.9 -5.8 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
PfGW456L13_931 -1.9 -7.0 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare
PfGW456L13_927 -1.9 -10.1 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare
PfGW456L13_4145 -1.9 -7.7 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_726 -1.9 -5.3 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_815 -1.9 -8.7 Putrescine utilization regulator compare
PfGW456L13_1847 -1.8 -1.4 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_2868 -1.8 -3.5 hypothetical protein compare
PfGW456L13_2511 -1.8 -2.3 short-chain dehydrogenase/reductase SDR compare
PfGW456L13_1655 -1.8 -2.3 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_1219 -1.8 -1.3 hypothetical protein compare
PfGW456L13_1733 -1.8 -4.7 Glycerol-3-phosphate regulon repressor, DeoR family compare
PfGW456L13_4001 -1.7 -10.8 Polysaccharide export lipoprotein Wza compare
PfGW456L13_1984 -1.7 -1.7 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_2941 -1.7 -1.7 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_5089 -1.7 -1.5 Transcription termination protein NusA compare
PfGW456L13_5048 -1.7 -3.0 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_5121 -1.6 -1.3 hypothetical protein compare
PfGW456L13_139 -1.6 -1.7 LSU ribosomal protein L9p compare
PfGW456L13_5082 -1.6 -5.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_1192 -1.6 -4.0 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_4642 -1.6 -2.3 Cold shock protein CspA compare
PfGW456L13_1057 -1.6 -6.5 Membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-) compare
PfGW456L13_117 -1.6 -7.8 Oxidoreductase, short chain dehydrogenase/reductase family conserved
PfGW456L13_1160 -1.6 -5.0 Putative DNA-binding protein in cluster with Type I restriction-modification system compare
PfGW456L13_3649 -1.6 -5.2 D-serine permease (from data) compare
PfGW456L13_2608 -1.6 -1.8 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
PfGW456L13_930 -1.5 -6.6 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
PfGW456L13_2223 -1.5 -7.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_1382 -1.5 -3.8 FOG: TPR repeat, SEL1 subfamily compare
PfGW456L13_2034 -1.5 -2.3 hypothetical protein compare
PfGW456L13_4002 -1.5 -5.4 YjbF outer membrane lipoprotein compare
PfGW456L13_2250 -1.5 -6.6 Probable protease htpX homolog (EC 3.4.24.-) compare
PfGW456L13_1628 -1.5 -4.8 ATPase, AFG1 family compare
PfGW456L13_4354 -1.5 -1.9 Flagellar hook-basal body complex protein FliE compare
PfGW456L13_4248 -1.5 -3.5 NLP/P60 family protein compare
PfGW456L13_4003 -1.5 -5.1 YjbG polysaccharide synthesis-related protein compare
PfGW456L13_5005 -1.5 -3.7 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_4254 -1.5 -5.0 FIG00955360: hypothetical protein compare
PfGW456L13_4992 -1.4 -9.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_1813 -1.4 -5.5 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_3795 -1.4 -7.1 sensor histidine kinase compare
PfGW456L13_4004 -1.4 -10.5 YjbH outer membrane lipoprotein compare
PfGW456L13_494 -1.4 -7.4 5-aminovalerate aminotransferase (EC 2.6.1.48) / Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) compare
PfGW456L13_1824 -1.4 -1.1 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_2221 -1.4 -7.3 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_4507 -1.3 -2.5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_198 -1.3 -7.2 acyltransferase family protein compare
PfGW456L13_4218 -1.3 -2.5 Quaternary ammonium compound-resistance protein SugE compare
PfGW456L13_990 -1.3 -2.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_4993 -1.3 -7.8 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
PfGW456L13_852 -1.3 -1.3 FIG00954215: hypothetical protein compare
PfGW456L13_4253 -1.3 -2.7 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_1067 -1.2 -3.1 FIG00955006: hypothetical protein compare
PfGW456L13_2252 -1.2 -6.8 Aspartate aminotransferase (EC 2.6.1.1) conserved
PfGW456L13_160 -1.2 -4.6 Epoxyqueuosine (oQ) reductase QueG compare
PfGW456L13_5008 -1.2 -1.1 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_1025 -1.2 -2.9 type IV pilus biogenesis protein PilJ compare
PfGW456L13_922 -1.2 -1.4 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_5112 -1.2 -1.3 tmRNA-binding protein SmpB compare
PfGW456L13_598 -1.2 -3.4 Zinc uptake regulation protein ZUR compare


Specific Phenotypes

For 12 genes in this experiment

For nitrogen source D-Serine in Pseudomonas fluorescens GW456-L13

For nitrogen source D-Serine across organisms