Experiment set3IT085 for Pseudomonas fluorescens GW456-L13

Compare to:

D-Serine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
PfGW456L13_4790 +2.8 23.0 D-serine/D-alanine/glycine transporter compare
PfGW456L13_812 +2.6 9.8 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
PfGW456L13_5096 +2.3 5.6 FIG004454: RNA binding protein compare
PfGW456L13_811 +2.3 8.7 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_152 +2.1 9.8 HflK protein compare
PfGW456L13_2185 +2.0 6.6 putative colanic acid biosynthesis glycosyl transferase compare
PfGW456L13_5060 +1.8 8.3 Peptide chain release factor 3 compare
PfGW456L13_420 +1.8 4.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_2186 +1.8 8.3 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) compare
PfGW456L13_2189 +1.8 9.4 UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid transferase compare
PfGW456L13_151 +1.7 6.5 HflC protein compare
PfGW456L13_203 +1.7 13.1 Glycosyl transferase in large core OS assembly cluster compare
PfGW456L13_1911 +1.7 12.0 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
PfGW456L13_73 +1.7 3.3 FIG00955840: hypothetical protein compare
PfGW456L13_200 +1.7 13.9 Glycosyl transferase in large core OS assembly cluster compare
PfGW456L13_201 +1.6 8.0 Hypothetical protein FIG015671 in large core OS assembly cluster compare
PfGW456L13_2191 +1.6 11.8 nucleotide sugar epimerase/dehydratase WbpM compare
PfGW456L13_1525 +1.6 10.1 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
PfGW456L13_199 +1.6 7.6 alpha-1,3-rhamnosyltransferase compare
PfGW456L13_3017 +1.5 3.2 Cold-shock DNA-binding domain compare
PfGW456L13_1526 +1.5 6.0 FIG00954153: hypothetical protein compare
PfGW456L13_375 +1.5 11.9 transport permease protein of gamma-aminobutyrate compare
PfGW456L13_427 +1.4 3.0 Two-component system response regulator OmpR compare
PfGW456L13_204 +1.4 12.0 Carbamoyltransferase in large core OS assembly cluster compare
PfGW456L13_2184 +1.4 5.7 putative polysaccharide polymerase compare
PfGW456L13_397 +1.3 7.8 Agmatine deiminase (EC 3.5.3.12) compare
PfGW456L13_2955 +1.3 4.4 RND efflux system, membrane fusion protein CmeA compare
PfGW456L13_3712 +1.3 6.1 hypothetical protein compare
PfGW456L13_157 +1.3 4.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
PfGW456L13_4365 +1.3 4.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
PfGW456L13_2589 +1.3 6.4 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) compare
PfGW456L13_4961 +1.2 6.0 Fumarylacetoacetase (EC 3.7.1.2) compare
PfGW456L13_354 +1.2 6.8 Periplasmic septal ring factor with murein hydrolase activity EnvC/YibP compare
PfGW456L13_2192 +1.2 4.6 regulator of length of O-antigen component of lipopolysaccharide chains compare
PfGW456L13_202 +1.2 5.0 Probable transcription regulator Mig-14 compare
PfGW456L13_995 +1.1 9.5 Cell division protein FtsX compare
PfGW456L13_3598 +1.1 2.4 hypothetical protein compare
PfGW456L13_1337 +1.1 5.9 DedA protein compare
PfGW456L13_4041 +1.1 2.8 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_4160 +1.1 1.7 FIG00958237: hypothetical protein compare
PfGW456L13_4264 +1.1 8.2 Branched-chain amino acid transport system carrier protein compare
PfGW456L13_2636 +1.1 5.1 FIG002776: hypothetical protein compare
PfGW456L13_3339 +1.0 5.7 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) compare
PfGW456L13_4737 +1.0 1.9 FIG00953063: hypothetical protein compare
PfGW456L13_2478 +1.0 3.5 FIG00956937: hypothetical protein compare
PfGW456L13_2159 +1.0 2.5 hypothetical protein compare
PfGW456L13_4788 +1.0 4.6 Bactoprenol-linked glucose translocase compare
PfGW456L13_155 +1.0 5.5 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
PfGW456L13_205 +1.0 4.3 hypothetical protein compare
PfGW456L13_4206 +1.0 2.8 Quinone oxidoreductase (EC 1.6.5.5) compare
PfGW456L13_2707 +0.9 1.4 FIG00953208: hypothetical protein compare
PfGW456L13_873 +0.9 5.0 Porphobilinogen synthase (EC 4.2.1.24) compare
PfGW456L13_5109 +0.9 2.5 UPF0125 protein yfjF compare
PfGW456L13_2954 +0.9 6.0 RND efflux system, inner membrane transporter CmeB compare
PfGW456L13_1770 +0.9 5.7 InaA protein compare
PfGW456L13_4424 +0.9 4.2 FIG00953416: hypothetical protein compare
PfGW456L13_3671 +0.9 2.6 hypothetical protein compare
PfGW456L13_1322 +0.9 1.5 Permeases of the major facilitator superfamily compare
PfGW456L13_3316 +0.9 1.2 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) compare
PfGW456L13_4674 +0.9 6.7 RNA polymerase sigma factor RpoS compare
PfGW456L13_5086 +0.9 3.0 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_4563 +0.9 2.3 Transcriptional activator protein LuxR compare
PfGW456L13_80 +0.9 4.0 ABC transporter (iron.B12.siderophore.hemin) , permease component compare
PfGW456L13_2897 +0.9 2.8 hypothetical protein compare
PfGW456L13_587 +0.9 6.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
PfGW456L13_1353 +0.9 2.7 hypothetical protein compare
PfGW456L13_577 +0.9 6.2 Fused spore maturation proteins A and B compare
PfGW456L13_4619 +0.8 2.9 Ribosomal protein S3 compare
PfGW456L13_3981 +0.8 2.3 hypothetical protein compare
PfGW456L13_4944 +0.8 1.0 FIG00963370: hypothetical protein compare
PfGW456L13_2702 +0.8 3.5 Glycine cleavage system transcriptional activator compare
PfGW456L13_3924 +0.8 2.2 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family compare
PfGW456L13_1625 +0.8 1.9 FIG00958649: hypothetical protein compare
PfGW456L13_2025 +0.8 3.9 Cytochrome c-type biogenesis protein ResA compare
PfGW456L13_3674 +0.8 3.0 Putative subunit of Alternative cytochrome c oxidase compare
PfGW456L13_4241 +0.8 2.1 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
PfGW456L13_4640 +0.8 2.5 FIG00955308: hypothetical protein compare
PfGW456L13_1370 +0.8 1.7 FIG00957593: hypothetical protein compare
PfGW456L13_1441 +0.8 2.1 Large-conductance mechanosensitive channel compare
PfGW456L13_609 +0.8 3.8 Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion compare
PfGW456L13_2816 +0.8 1.4 Various polyols ABC transporter, ATP-binding component compare
PfGW456L13_2924 +0.8 4.0 Glutathione reductase (EC 1.8.1.7) compare
PfGW456L13_2190 +0.8 2.8 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
PfGW456L13_97 +0.8 2.8 membrane protein, putative compare
PfGW456L13_1643 +0.8 3.7 rRNA small subunit methyltransferase I compare
PfGW456L13_78 +0.7 2.8 ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component compare
PfGW456L13_39 +0.7 0.8 Permeases of the major facilitator superfamily compare
PfGW456L13_1900 +0.7 4.4 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_896 +0.7 5.6 Xaa-Pro aminopeptidase (EC 3.4.11.9) compare
PfGW456L13_2857 +0.7 1.2 ChlD component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_4233 +0.7 0.9 Transcriptional regulator, MarR family compare
PfGW456L13_3634 +0.7 2.0 Transcriptional regulator compare
PfGW456L13_4789 +0.7 5.4 OpgC protein compare
PfGW456L13_1181 +0.7 1.2 hypothetical protein compare
PfGW456L13_4026 +0.7 2.0 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_273 +0.7 1.0 hypothetical protein compare
PfGW456L13_3355 +0.7 2.8 NnrS protein involved in response to NO compare
PfGW456L13_2952 +0.7 2.1 2-ketogluconate utilization repressor PtxS compare
PfGW456L13_906 +0.7 2.0 Putative activity regulator of membrane protease YbbK compare
PfGW456L13_4582 +0.7 2.6 RND efflux system, outer membrane lipoprotein CmeC compare
PfGW456L13_1985 +0.7 2.0 Alginate biosynthesis transcriptional activator compare
PfGW456L13_2866 +0.7 2.3 Transcriptional regulator, IclR family compare
PfGW456L13_4807 +0.7 5.6 ATP-dependent protease La (EC 3.4.21.53) Type I compare
PfGW456L13_426 +0.7 3.7 Osmolarity sensory histidine kinase EnvZ compare
PfGW456L13_1912 +0.7 1.5 FIG00954271: hypothetical protein compare
PfGW456L13_3232 +0.7 1.4 hypothetical protein compare
PfGW456L13_3466 +0.7 1.0 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
PfGW456L13_858 +0.7 2.9 Uroporphyrinogen-III synthase (EC 4.2.1.75) compare
PfGW456L13_1349 +0.7 1.5 MaoC-like domain protein compare
PfGW456L13_1757 +0.7 3.4 Electron transport complex protein RnfB compare
PfGW456L13_2291 +0.7 4.4 Periplasmic binding protein compare
PfGW456L13_2767 +0.7 3.9 phage integrase, putative compare
PfGW456L13_3683 +0.7 1.8 FIG00957787: hypothetical protein compare
PfGW456L13_1829 +0.7 1.9 glycosyl transferase, group 1 family protein compare
PfGW456L13_4494 +0.7 4.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_872 +0.6 3.6 FIG139438: lipoprotein B compare
PfGW456L13_343 +0.6 2.6 hypothetical protein compare
PfGW456L13_4120 +0.6 2.7 FIG008443: hypothetical protein compare
PfGW456L13_1498 +0.6 1.3 FIG060329: MOSC domain protein compare
PfGW456L13_4847 +0.6 1.8 DNA polymerase III chi subunit (EC 2.7.7.7) compare
PfGW456L13_1375 +0.6 3.8 Putative membrane protein compare
PfGW456L13_4134 +0.6 1.1 hypothetical protein compare
PfGW456L13_3991 +0.6 4.6 Capsular polysaccharide biosynthesis protein compare
PfGW456L13_4661 +0.6 2.5 Diacylglycerol kinase (EC 2.7.1.107) compare
PfGW456L13_11 +0.6 2.9 transcriptional regulator, MerR family compare
PfGW456L13_3124 +0.6 1.8 hypothetical protein compare
PfGW456L13_4639 +0.6 0.6 Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) compare
PfGW456L13_4035 +0.6 0.8 Cell division inhibitor-related protein compare
PfGW456L13_3995 +0.6 3.9 UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) compare
PfGW456L13_4281 +0.6 4.5 Nucleoside ABC transporter, periplasmic nucleoside-binding protein compare
PfGW456L13_1017 +0.6 1.6 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
PfGW456L13_1767 +0.6 2.5 DNA-binding response regulator ColR compare
PfGW456L13_4874 +0.6 2.1 Iron-sulfur cluster regulator IscR compare
PfGW456L13_1527 +0.6 3.4 glutamyl-Q-tRNA synthetase compare
PfGW456L13_4581 +0.6 4.8 RND efflux system, inner membrane transporter CmeB compare
PfGW456L13_4045 +0.6 4.5 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) compare
PfGW456L13_1012 +0.6 2.0 Twitching motility protein PilT compare
PfGW456L13_4172 +0.6 1.5 Smr domain protein compare
PfGW456L13_1990 +0.6 1.4 hypothetical protein compare
PfGW456L13_668 +0.6 1.3 Ribonuclease P protein component (EC 3.1.26.5) compare
PfGW456L13_1751 +0.6 1.8 DNA-binding response regulator, LuxR family compare
PfGW456L13_2268 +0.6 1.6 Thiol-disulfide isomerase and thioredoxins compare
PfGW456L13_4238 +0.6 2.7 Cobyric acid synthase (EC 6.3.5.10) compare
PfGW456L13_71 +0.6 2.9 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
PfGW456L13_4932 +0.6 3.9 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
PfGW456L13_3999 +0.6 2.9 N-acetylmannosaminyltransferase (EC 2.4.1.187) compare
PfGW456L13_3667 +0.6 1.0 hypothetical protein compare
PfGW456L13_1009 +0.6 1.6 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_2557 +0.6 3.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_3356 +0.6 1.2 hypothetical protein compare
PfGW456L13_3107 +0.6 1.4 Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) compare
PfGW456L13_1171 +0.6 4.1 Lysine 2-monooxygenase (EC 1.13.12.2) (from data) compare
PfGW456L13_4662 +0.6 0.9 Transcriptional regulator, LuxR family compare
PfGW456L13_238 +0.6 2.3 FIG017861: hypothetical protein compare
PfGW456L13_5113 +0.6 4.5 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
PfGW456L13_421 +0.6 1.4 hypothetical protein compare
PfGW456L13_2918 +0.6 1.7 FIG00954920: hypothetical protein compare
PfGW456L13_3231 +0.6 3.7 Site-specific recombinase, phage integrase family compare
PfGW456L13_240 +0.6 1.6 FIG143263: Glycosyl transferase compare
PfGW456L13_3138 +0.6 1.6 phosphoesterase, putative compare
PfGW456L13_1178 +0.5 3.1 Phage integrase compare
PfGW456L13_1131 +0.5 1.5 FIG00953361: hypothetical protein compare
PfGW456L13_5097 +0.5 3.0 hypothetical protein compare
PfGW456L13_4228 +0.5 2.3 FIG00956435: hypothetical protein compare
PfGW456L13_1918 +0.5 2.3 ABC-type phosphate/phosphonate transport system, periplasmic component compare
PfGW456L13_70 +0.5 2.9 Cobalt-precorrin-6 synthase, anaerobic compare
PfGW456L13_545 +0.5 2.0 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
PfGW456L13_1954 +0.5 1.1 hypothetical protein compare
PfGW456L13_1240 +0.5 3.0 FIG00956941: hypothetical protein compare
PfGW456L13_1537 +0.5 1.2 Hypothetical protein YqcC (clustered with tRNA pseudouridine synthase C) compare
PfGW456L13_3985 +0.5 3.9 hypothetical protein compare
PfGW456L13_2261 +0.5 1.4 DNA-binding response regulator, LuxR family compare
PfGW456L13_392 +0.5 2.2 FIG00459469: hypothetical protein compare
PfGW456L13_5021 +0.5 2.7 FOG: TPR repeat compare
PfGW456L13_4135 +0.5 0.9 hypothetical protein compare
PfGW456L13_1848 +0.5 0.9 hypothetical protein compare
PfGW456L13_654 +0.5 1.2 Chaperone protein YscY (Yop proteins translocation protein Y) compare
PfGW456L13_2600 +0.5 2.5 Histone acetyltransferase HPA2 and related acetyltransferases compare
PfGW456L13_4343 +0.5 1.9 Flagellar biosynthesis protein FliL compare
PfGW456L13_4585 +0.5 1.2 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) compare
PfGW456L13_4576 +0.5 1.2 Transcriptional regulator, ArsR family compare
PfGW456L13_2620 +0.5 0.9 Glutamine amidotransferase class-I (EC 6.3.5.2) compare
PfGW456L13_4289 +0.5 2.4 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_2382 +0.5 2.0 Glyoxalase family protein compare
PfGW456L13_1738 +0.5 1.8 Ferric iron ABC transporter, ATP-binding protein compare
PfGW456L13_4028 +0.5 1.3 FIG00954981: hypothetical protein compare
PfGW456L13_4355 +0.5 1.8 Flagellar regulatory protein FleQ compare
PfGW456L13_900 +0.5 3.7 Ferric iron ABC transporter, iron-binding protein compare
PfGW456L13_1494 +0.5 4.1 COG1496: Uncharacterized conserved protein compare
PfGW456L13_233 +0.5 2.5 Chromosome (plasmid) partitioning protein ParA compare
PfGW456L13_1138 +0.5 0.8 response regulator compare
PfGW456L13_1869 +0.5 2.5 glycine cleavage system H protein (EC 1.4.1.27) (from data) compare
PfGW456L13_207 +0.5 1.8 InaA protein compare
PfGW456L13_4091 +0.5 2.9 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
PfGW456L13_3718 +0.5 1.5 Dihydrofolate reductase (EC 1.5.1.3) compare
PfGW456L13_808 +0.5 1.5 FIG00957579: hypothetical protein compare
PfGW456L13_1865 +0.5 0.8 Cold shock protein CspA compare
PfGW456L13_4607 +0.5 0.7 hypothetical protein compare
PfGW456L13_84 +0.5 1.7 Urea ABC transporter, ATPase protein UrtD compare
PfGW456L13_1172 +0.5 2.6 Transcriptional regulator, AsnC family compare


Specific Phenotypes

For 12 genes in this experiment

For nitrogen source D-Serine in Pseudomonas fluorescens GW456-L13

For nitrogen source D-Serine across organisms