Experiment set3IT078 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Alanine nitrogen source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_3948 -6.2 -4.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_362 -6.2 -6.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_1222 -6.2 -4.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_303 -5.9 -4.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_5001 -5.8 -8.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_3947 -5.7 -3.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_644 -5.6 -8.5 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_361 -5.6 -11.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_3934 -5.5 -11.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_1010 -5.5 -7.6 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_272 -5.4 -29.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_347 -5.4 -9.0 Nitrogen regulation protein NR(I) compare
PfGW456L13_811 -5.4 -5.2 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_172 -5.3 -9.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_359 -5.3 -10.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_1540 -5.3 -11.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_1472 -5.3 -6.3 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_5000 -5.3 -14.4 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_3940 -5.2 -9.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1368 -5.2 -5.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_565 -5.1 -5.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_3945 -5.1 -11.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_973 -5.1 -12.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_1233 -5.0 -3.4 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_271 -5.0 -18.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_1221 -4.9 -16.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_728 -4.9 -14.7 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_1007 -4.9 -11.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_913 -4.8 -6.6 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_149 -4.8 -8.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_951 -4.8 -13.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_2032 -4.8 -4.7 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_1217 -4.8 -20.4 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_2230 -4.8 -11.5 Cys regulon transcriptional activator CysB compare
PfGW456L13_845 -4.8 -5.7 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_1749 -4.8 -3.3 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_2046 -4.7 -7.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_2842 -4.7 -7.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1739 -4.6 -10.8 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_727 -4.6 -10.4 LysR family transcriptional regulator PA5437 compare
PfGW456L13_779 -4.6 -12.9 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_812 -4.5 -3.1 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
PfGW456L13_1050 -4.4 -9.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_4009 -4.4 -15.0 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_1539 -4.4 -13.1 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_2843 -4.3 -11.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_358 -4.3 -3.8 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_2656 -4.2 -9.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1538 -4.2 -12.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_302 -4.1 -6.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_2176 -4.1 -7.1 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_1006 -4.0 -5.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_854 -4.0 -3.9 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_4165 -4.0 -5.4 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_1524 -4.0 -7.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_1889 -3.9 -2.7 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_1147 -3.8 -13.9 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_729 -3.7 -11.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_5067 -3.7 -11.7 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_943 -3.6 -8.0 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_275 -3.6 -2.4 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_1973 -3.5 -6.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_1615 -3.5 -3.1 Probable transmembrane protein compare
PfGW456L13_2103 -3.5 -5.9 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_1901 -3.4 -10.3 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_4125 -3.4 -3.2 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_1972 -3.4 -3.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_1148 -3.3 -14.5 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_50 -3.2 -9.4 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_793 -3.2 -3.8 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_566 -3.2 -8.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_2941 -3.2 -3.3 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_1220 -3.2 -7.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_2035 -3.2 -12.5 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_4859 -3.2 -4.3 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_3960 -3.1 -9.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_4711 -3.1 -17.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_1363 -3.1 -5.6 Rare lipoprotein A precursor compare
PfGW456L13_1150 -3.1 -12.4 Biotin synthesis protein BioC compare
PfGW456L13_4854 -3.1 -8.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_953 -3.0 -13.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_1479 -2.9 -1.9 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
PfGW456L13_1151 -2.9 -8.4 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_276 -2.9 -2.6 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_5006 -2.8 -2.7 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_1044 -2.7 -10.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_949 -2.5 -11.8 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_4236 -2.3 -3.9 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
PfGW456L13_2623 -2.3 -3.1 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_360 -2.3 -2.5 FIG00956267: hypothetical protein compare
PfGW456L13_4842 -2.3 -3.6 Translation elongation factor LepA compare
PfGW456L13_656 -2.2 -4.2 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_5008 -2.2 -2.6 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_4999 -2.1 -10.0 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_952 -2.1 -4.4 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_150 -2.0 -1.5 hypothetical protein compare
PfGW456L13_1553 -2.0 -8.4 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_477 -2.0 -1.8 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_346 -1.9 -2.6 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
PfGW456L13_726 -1.9 -8.6 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_1984 -1.9 -3.2 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_1574 -1.8 -3.9 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_1735 -1.7 -3.7 Glycerol uptake facilitator protein compare
PfGW456L13_1520 -1.7 -5.0 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
PfGW456L13_5089 -1.6 -1.9 Transcription termination protein NusA compare
PfGW456L13_3795 -1.5 -7.6 sensor histidine kinase compare
PfGW456L13_1845 -1.5 -2.8 Cold shock protein CspC compare
PfGW456L13_1842 -1.5 -8.4 Outer membrane porin, OprD family compare
PfGW456L13_4012 -1.5 -2.1 VacJ-like lipoprotein precursor compare
PfGW456L13_59 -1.5 -5.8 Sensor histidine kinase/response regulator compare
PfGW456L13_4088 -1.5 -2.9 Transcriptional regulator, GntR family compare
PfGW456L13_1219 -1.5 -1.6 hypothetical protein compare
PfGW456L13_355 -1.4 -4.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_4207 -1.4 -4.8 Periplasmic protease compare
PfGW456L13_1628 -1.4 -4.6 ATPase, AFG1 family compare
PfGW456L13_2552 -1.4 -5.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1813 -1.4 -6.2 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_4037 -1.4 -4.6 FIG00953287: hypothetical protein compare
PfGW456L13_2851 -1.4 -4.6 Cobalt-precorrin-3b C17-methyltransferase compare
PfGW456L13_874 -1.4 -10.7 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_4882 -1.4 -2.8 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_875 -1.4 -4.4 Exopolyphosphatase (EC 3.6.1.11) compare
PfGW456L13_4507 -1.3 -3.5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_4253 -1.3 -3.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_2551 -1.3 -2.4 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_5150 -1.3 -2.3 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_4238 -1.3 -4.0 Cobyric acid synthase (EC 6.3.5.10) compare
PfGW456L13_5060 -1.3 -3.8 Peptide chain release factor 3 compare
PfGW456L13_2107 -1.3 -3.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
PfGW456L13_2632 -1.3 -3.1 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_1521 -1.3 -2.7 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
PfGW456L13_3309 -1.2 -1.9 Glutathione S-transferase family protein compare
PfGW456L13_1838 -1.2 -3.8 Sensory box histidine kinase compare
PfGW456L13_4671 -1.2 -4.8 Transcriptional regulator, Cro/CI family compare
PfGW456L13_4239 -1.2 -1.7 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
PfGW456L13_2084 -1.2 -2.4 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_4641 -1.2 -1.7 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
PfGW456L13_3610 -1.1 -1.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_5112 -1.1 -1.4 tmRNA-binding protein SmpB compare
PfGW456L13_274 -1.1 -7.6 DamX, an inner membrane protein involved in bile resistance compare
PfGW456L13_3000 -1.1 -2.0 FIG00961385: hypothetical protein compare
PfGW456L13_69 -1.1 -1.3 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
PfGW456L13_1981 -1.1 -3.1 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_67 -1.1 -4.5 Cobalamin biosynthesis protein CobG compare
PfGW456L13_5005 -1.1 -3.4 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_3289 -1.1 -2.8 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
PfGW456L13_1927 -1.1 -4.9 Gluconate permease compare
PfGW456L13_4607 -1.1 -1.9 hypothetical protein compare
PfGW456L13_2034 -1.1 -1.8 hypothetical protein compare
PfGW456L13_3810 -1.1 -1.7 hypothetical protein compare
PfGW456L13_4668 -1.1 -4.1 RecA protein compare
PfGW456L13_5017 -1.1 -2.9 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_1824 -1.1 -1.8 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_1865 -1.1 -1.5 Cold shock protein CspA compare
PfGW456L13_4883 -1.1 -3.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
PfGW456L13_296 -1.0 -2.6 Polyhydroxyalkanoate granule-associated protein PhaF compare
PfGW456L13_787 -1.0 -5.5 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_1655 -1.0 -1.5 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_2553 -1.0 -5.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_4259 -1.0 -1.9 FIG00953296: hypothetical protein compare
PfGW456L13_3260 -1.0 -1.2 hypothetical protein compare
PfGW456L13_3302 -1.0 -1.2 FIG00954674: hypothetical protein compare
PfGW456L13_5048 -1.0 -2.2 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_2631 -1.0 -2.2 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_757 -1.0 -2.4 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_2856 -1.0 -3.4 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_3704 -1.0 -2.9 Transcriptional regulator RpiR in protein degradation cluster compare
PfGW456L13_2237 -0.9 -1.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4240 -0.9 -5.9 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
PfGW456L13_4242 -0.9 -5.3 Cobyrinic acid A,C-diamide synthase compare
PfGW456L13_4662 -0.9 -1.2 Transcriptional regulator, LuxR family compare
PfGW456L13_944 -0.9 -5.7 D-2-hydroxyglutarate dehydrogenase compare
PfGW456L13_1011 -0.9 -1.4 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_1860 -0.9 -4.1 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
PfGW456L13_2850 -0.9 -6.1 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
PfGW456L13_2933 -0.9 -2.8 LysR family transcriptional regulator STM2281 compare
PfGW456L13_4237 -0.9 -2.7 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
PfGW456L13_4610 -0.9 -1.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
PfGW456L13_1525 -0.8 -4.2 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
PfGW456L13_2436 -0.8 -3.1 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_3398 -0.8 -3.0 Transcriptional regulator, TetR family compare
PfGW456L13_3941 -0.8 -5.3 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
PfGW456L13_1223 -0.8 -2.7 Lipoate-protein ligase A compare
PfGW456L13_4234 -0.8 -3.3 Cobalamin synthase compare
PfGW456L13_2232 -0.8 -1.7 FIG00957049: hypothetical protein compare
PfGW456L13_4254 -0.8 -3.1 FIG00955360: hypothetical protein compare
PfGW456L13_3634 -0.8 -2.1 Transcriptional regulator compare
PfGW456L13_1847 -0.8 -1.1 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_3409 -0.8 -1.9 Transcriptional regulator, IclR family compare
PfGW456L13_1580 -0.8 -3.5 FIG140336: TPR domain protein compare
PfGW456L13_4248 -0.8 -2.2 NLP/P60 family protein compare
PfGW456L13_4451 -0.8 -3.6 ATP-dependent RNA helicase SrmB compare
PfGW456L13_1853 -0.8 -1.6 Holliday junction DNA helicase RuvB compare
PfGW456L13_2190 -0.8 -2.5 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
PfGW456L13_2931 -0.8 -1.6 transcriptional regulator MvaT, P16 subunit, putative compare
PfGW456L13_4992 -0.8 -6.0 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_784 -0.8 -3.7 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_151 -0.8 -2.0 HflC protein compare
PfGW456L13_139 -0.8 -1.3 LSU ribosomal protein L9p compare
PfGW456L13_5082 -0.8 -3.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens GW456-L13 in nitrogen source experiments

For nitrogen source L-Alanine across organisms