Experiment set3IT072 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Serine nitrogen source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_358 -6.2 -4.2 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_347 -6.1 -6.0 Nitrogen regulation protein NR(I) compare
PfGW456L13_644 -6.1 -5.9 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_303 -5.7 -4.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_1368 -5.6 -3.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_149 -5.5 -6.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_3934 -5.5 -11.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_3948 -5.4 -6.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_362 -5.4 -7.5 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_361 -5.3 -11.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_3947 -5.2 -5.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1472 -5.2 -6.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_1540 -5.2 -11.0 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_1007 -5.2 -9.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_2046 -5.1 -6.9 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_3940 -5.0 -9.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_2842 -5.0 -5.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_272 -4.9 -26.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_913 -4.9 -5.8 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_2843 -4.9 -9.3 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_3945 -4.8 -12.0 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_4954 -4.7 -16.7 L-serine ammonia-lyase (EC 4.3.1.17) (from data) conserved
PfGW456L13_5001 -4.7 -10.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_5000 -4.7 -15.1 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_271 -4.7 -17.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_973 -4.7 -12.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_1222 -4.6 -6.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_359 -4.6 -8.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_845 -4.6 -5.5 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_1217 -4.6 -20.5 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_727 -4.5 -10.5 LysR family transcriptional regulator PA5437 compare
PfGW456L13_1221 -4.5 -14.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_779 -4.4 -12.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_1739 -4.4 -11.1 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_1233 -4.4 -4.3 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1050 -4.4 -9.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_854 -4.4 -3.0 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_2032 -4.4 -5.2 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_302 -4.3 -7.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_1972 -4.3 -3.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_951 -4.3 -13.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_2230 -4.2 -11.4 Cys regulon transcriptional activator CysB compare
PfGW456L13_1010 -4.2 -9.0 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_2176 -3.9 -6.7 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_565 -3.9 -7.0 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_566 -3.9 -8.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_1538 -3.8 -12.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1220 -3.8 -7.7 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1006 -3.8 -6.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_728 -3.8 -14.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_4009 -3.7 -13.8 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_276 -3.6 -2.3 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_4165 -3.6 -5.4 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_1539 -3.6 -12.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_1889 -3.6 -3.4 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_2656 -3.5 -8.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_4711 -3.5 -17.9 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_2103 -3.5 -6.3 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_275 -3.5 -2.4 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_729 -3.4 -11.7 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_1749 -3.4 -5.9 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_1615 -3.4 -3.0 Probable transmembrane protein compare
PfGW456L13_4854 -3.3 -9.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_1973 -3.2 -6.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_4125 -3.2 -3.0 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_4012 -3.1 -2.1 VacJ-like lipoprotein precursor compare
PfGW456L13_1524 -3.1 -6.6 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_5006 -3.1 -2.1 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_5003 -3.1 -3.0 YrbA protein compare
PfGW456L13_874 -3.1 -19.1 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_2035 -3.0 -11.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_50 -3.0 -8.8 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_1363 -3.0 -6.8 Rare lipoprotein A precursor compare
PfGW456L13_5008 -2.9 -2.8 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_3960 -2.8 -11.0 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_793 -2.8 -3.8 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_1147 -2.7 -12.3 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_1151 -2.6 -9.1 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_3610 -2.6 -3.3 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_5067 -2.6 -10.9 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_949 -2.6 -10.8 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_1735 -2.6 -3.9 Glycerol uptake facilitator protein compare
PfGW456L13_1148 -2.6 -13.5 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_346 -2.5 -3.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
PfGW456L13_2941 -2.5 -3.8 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_4859 -2.4 -4.5 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_1150 -2.3 -11.0 Biotin synthesis protein BioC compare
PfGW456L13_1219 -2.3 -3.4 hypothetical protein compare
PfGW456L13_1044 -2.2 -10.5 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_892 -2.2 -8.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
PfGW456L13_4953 -2.2 -4.0 Glycine cleavage system transcriptional activator compare
PfGW456L13_757 -2.1 -2.8 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_1901 -2.1 -8.7 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_494 -2.1 -10.1 5-aminovalerate aminotransferase (EC 2.6.1.48) / Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) compare
PfGW456L13_4145 -2.0 -6.7 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1845 -2.0 -3.5 Cold shock protein CspC compare
PfGW456L13_1391 -2.0 -3.3 Transcriptional regulator, AsnC family compare
PfGW456L13_953 -2.0 -11.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_1824 -1.9 -1.5 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_751 -1.9 -4.1 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
PfGW456L13_66 -1.9 -1.6 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
PfGW456L13_1553 -1.8 -8.2 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_1984 -1.8 -3.2 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_2552 -1.8 -6.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1655 -1.8 -2.5 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_726 -1.8 -7.3 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_1284 -1.8 -2.9 Putative transport protein compare
PfGW456L13_927 -1.8 -11.9 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare
PfGW456L13_4671 -1.7 -6.6 Transcriptional regulator, Cro/CI family compare
PfGW456L13_360 -1.7 -2.3 FIG00956267: hypothetical protein compare
PfGW456L13_329 -1.7 -3.7 Histidine utilization repressor compare
PfGW456L13_4842 -1.6 -3.0 Translation elongation factor LepA compare
PfGW456L13_3398 -1.6 -3.0 Transcriptional regulator, TetR family compare
PfGW456L13_4999 -1.6 -8.4 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_756 -1.5 -4.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_2857 -1.5 -2.4 ChlD component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_59 -1.4 -5.5 Sensor histidine kinase/response regulator compare
PfGW456L13_2632 -1.4 -2.3 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_5121 -1.4 -1.5 hypothetical protein compare
PfGW456L13_3052 -1.4 -1.5 Response regulator compare
PfGW456L13_4088 -1.4 -1.9 Transcriptional regulator, GntR family compare
PfGW456L13_1625 -1.3 -3.3 FIG00958649: hypothetical protein compare
PfGW456L13_5150 -1.3 -1.8 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_1853 -1.3 -3.1 Holliday junction DNA helicase RuvB compare
PfGW456L13_5011 -1.3 -2.5 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
PfGW456L13_2556 -1.3 -2.0 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
PfGW456L13_4545 -1.2 -1.5 Integral membrane protein compare
PfGW456L13_5112 -1.2 -1.5 tmRNA-binding protein SmpB compare
PfGW456L13_5005 -1.2 -3.4 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_3379 -1.2 -4.9 Serine transporter compare
PfGW456L13_2623 -1.2 -1.3 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_4207 -1.2 -4.6 Periplasmic protease compare
PfGW456L13_2649 -1.2 -3.2 Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) compare
PfGW456L13_2436 -1.2 -4.0 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1479 -1.2 -1.2 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
PfGW456L13_2981 -1.2 -1.8 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_4041 -1.2 -1.5 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_4035 -1.2 -1.6 Cell division inhibitor-related protein compare
PfGW456L13_1238 -1.2 -3.2 Biotin operon repressor / Biotin-protein ligase (EC 6.3.4.15) compare
PfGW456L13_928 -1.1 -5.8 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
PfGW456L13_2142 -1.1 -8.4 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
PfGW456L13_930 -1.1 -5.7 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
PfGW456L13_3808 -1.1 -2.6 Predicted transcriptional regulator of NADH dehydrogenase, Rrf2 family compare
PfGW456L13_1580 -1.1 -5.4 FIG140336: TPR domain protein compare
PfGW456L13_3442 -1.1 -3.3 hypothetical protein compare
PfGW456L13_2150 -1.1 -2.7 Carbon storage regulator compare
PfGW456L13_67 -1.1 -3.9 Cobalamin biosynthesis protein CobG compare
PfGW456L13_2170 -1.1 -3.1 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
PfGW456L13_2831 -1.1 -2.1 Transcriptional regulator, GntR family compare
PfGW456L13_3354 -1.1 -2.8 hypothetical protein compare
PfGW456L13_1863 -1.0 -5.7 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_1842 -1.0 -5.7 Outer membrane porin, OprD family compare
PfGW456L13_4337 -1.0 -1.9 Flagellar biosynthesis protein FliR compare
PfGW456L13_3427 -1.0 -2.4 Enoyl-CoA hydratase (EC 4.2.1.17) compare
PfGW456L13_3795 -1.0 -4.6 sensor histidine kinase compare
PfGW456L13_2826 -1.0 -1.1 hypothetical protein compare
PfGW456L13_319 -1.0 -2.2 hypothetical protein compare
PfGW456L13_1447 -1.0 -1.1 Transcriptional regulator, GntR family compare
PfGW456L13_5017 -1.0 -2.4 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_323 -1.0 -2.4 Histidine ABC transporter, permease protein (TC 3.A.1) compare
PfGW456L13_355 -1.0 -3.4 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_4240 -1.0 -5.2 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
PfGW456L13_931 -1.0 -4.3 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare
PfGW456L13_2581 -0.9 -3.1 Transmembrane regulator protein PrtR compare
PfGW456L13_3386 -0.9 -2.3 Glutathione peroxidase family protein compare
PfGW456L13_3291 -0.9 -1.9 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
PfGW456L13_1850 -0.9 -4.3 FIG000859: hypothetical protein YebC compare
PfGW456L13_5074 -0.9 -1.2 1-phosphofructokinase (EC 2.7.1.56) compare
PfGW456L13_1813 -0.9 -4.4 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_1997 -0.9 -3.1 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_282 -0.9 -6.6 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
PfGW456L13_2034 -0.9 -1.2 hypothetical protein compare
PfGW456L13_512 -0.9 -2.9 Putative membrane-bound ClpP-class protease associated with aq_911 compare
PfGW456L13_3937 -0.9 -2.2 DedD protein compare
PfGW456L13_5241 -0.9 -2.0 tRNA-Thr-CGT compare
PfGW456L13_5048 -0.9 -1.7 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_296 -0.9 -1.6 Polyhydroxyalkanoate granule-associated protein PhaF compare
PfGW456L13_3894 -0.9 -1.1 Integration host factor alpha subunit compare
PfGW456L13_4477 -0.9 -2.4 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
PfGW456L13_4234 -0.9 -3.0 Cobalamin synthase compare
PfGW456L13_2553 -0.9 -4.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_322 -0.9 -2.4 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
PfGW456L13_1981 -0.9 -2.7 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_273 -0.8 -1.7 hypothetical protein compare
PfGW456L13_1927 -0.8 -5.0 Gluconate permease compare
PfGW456L13_2327 -0.8 -2.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_4882 -0.8 -1.8 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_2908 -0.8 -1.9 hypothetical protein compare
PfGW456L13_1628 -0.8 -3.4 ATPase, AFG1 family compare
PfGW456L13_1852 -0.8 -3.4 Holliday junction DNA helicase RuvA compare
PfGW456L13_2297 -0.8 -2.7 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
PfGW456L13_787 -0.8 -4.7 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_1700 -0.8 -5.1 Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4) compare
PfGW456L13_4037 -0.8 -1.1 FIG00953287: hypothetical protein compare
PfGW456L13_2250 -0.8 -5.4 Probable protease htpX homolog (EC 3.4.24.-) compare
PfGW456L13_1382 -0.8 -3.7 FOG: TPR repeat, SEL1 subfamily compare
PfGW456L13_1441 -0.8 -1.4 Large-conductance mechanosensitive channel compare
PfGW456L13_2856 -0.8 -2.1 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_4033 -0.8 -1.4 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
PfGW456L13_4607 -0.8 -1.8 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For nitrogen source L-Serine in Pseudomonas fluorescens GW456-L13

For nitrogen source L-Serine across organisms