Experiment set3IT068 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Histidine nitrogen source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_1521 -6.0 -4.1 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
PfGW456L13_1007 -5.9 -7.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_3948 -5.9 -4.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_973 -5.8 -9.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_3934 -5.8 -8.9 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_1540 -5.7 -6.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_1222 -5.7 -5.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_1368 -5.6 -3.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_1010 -5.6 -6.7 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_1220 -5.6 -10.7 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1472 -5.5 -5.4 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_3940 -5.5 -6.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1539 -5.5 -6.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_172 -5.4 -9.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_644 -5.4 -8.3 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_565 -5.4 -3.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_3947 -5.4 -3.7 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_2046 -5.4 -5.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_727 -5.3 -9.4 LysR family transcriptional regulator PA5437 compare
PfGW456L13_779 -5.2 -10.6 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_1217 -5.2 -21.5 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_3945 -5.1 -9.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_2230 -5.0 -9.1 Cys regulon transcriptional activator CysB compare
PfGW456L13_1050 -5.0 -7.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_1233 -4.9 -3.4 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_2842 -4.9 -5.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_728 -4.9 -14.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_913 -4.8 -6.6 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_316 -4.8 -15.0 N-formylglutamate deformylase (EC 3.5.1.68) (from data) conserved
PfGW456L13_2656 -4.7 -5.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_845 -4.7 -6.4 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_1221 -4.6 -14.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1147 -4.6 -15.0 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_2032 -4.6 -4.5 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_854 -4.5 -3.1 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_1739 -4.5 -10.1 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_1524 -4.5 -5.3 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_330 -4.4 -12.4 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) conserved
PfGW456L13_1749 -4.3 -4.2 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_1520 -4.3 -4.3 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
PfGW456L13_1538 -4.3 -11.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_3960 -4.2 -10.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_2176 -4.2 -7.1 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_1615 -4.2 -2.8 Probable transmembrane protein compare
PfGW456L13_1363 -4.2 -6.3 Rare lipoprotein A precursor compare
PfGW456L13_4009 -4.2 -12.3 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_2103 -4.1 -5.8 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_1021 -4.0 -5.5 Glutathione synthetase (EC 6.3.2.3) compare
PfGW456L13_949 -3.8 -14.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_1889 -3.8 -2.6 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_276 -3.8 -2.5 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_1901 -3.7 -9.5 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_317 -3.7 -9.2 Imidazolonepropionase (EC 3.5.2.7) (from data) conserved
PfGW456L13_272 -3.6 -22.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_5082 -3.6 -7.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_892 -3.6 -12.0 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
PfGW456L13_793 -3.6 -3.5 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_729 -3.6 -11.2 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_5067 -3.5 -10.9 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_275 -3.5 -2.4 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_271 -3.5 -15.9 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_4165 -3.5 -5.3 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_566 -3.5 -8.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_943 -3.5 -7.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_1006 -3.5 -5.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_4854 -3.3 -8.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_2843 -3.3 -7.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_50 -3.1 -8.8 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_1150 -3.0 -14.5 Biotin synthesis protein BioC compare
PfGW456L13_4012 -3.0 -2.0 VacJ-like lipoprotein precursor compare
PfGW456L13_4859 -2.9 -4.3 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_1148 -2.8 -14.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_1863 -2.8 -8.8 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_1151 -2.8 -9.3 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_1044 -2.7 -11.4 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_787 -2.7 -9.9 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_1735 -2.7 -3.6 Glycerol uptake facilitator protein compare
PfGW456L13_430 -2.5 -8.7 Glutamate--cysteine ligase (EC 6.3.2.2) compare
PfGW456L13_2107 -2.4 -5.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
PfGW456L13_320 -2.3 -5.8 Histidine ammonia-lyase (EC 4.3.1.3) (from data) conserved
PfGW456L13_1972 -2.3 -2.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_1655 -2.3 -2.5 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_1845 -2.2 -3.6 Cold shock protein CspC compare
PfGW456L13_3179 -2.2 -3.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2941 -2.2 -3.1 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_672 -2.1 -5.3 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
PfGW456L13_1927 -2.1 -9.0 Gluconate permease compare
PfGW456L13_1219 -2.0 -1.8 hypothetical protein compare
PfGW456L13_4517 -2.0 -12.0 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_1838 -2.0 -4.6 Sensory box histidine kinase compare
PfGW456L13_3409 -1.9 -2.2 Transcriptional regulator, IclR family compare
PfGW456L13_59 -1.9 -6.6 Sensor histidine kinase/response regulator compare
PfGW456L13_1553 -1.9 -8.2 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_2885 -1.9 -7.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
PfGW456L13_4243 -1.8 -3.3 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) compare
PfGW456L13_1981 -1.8 -5.1 Aspartokinase (EC 2.7.2.4) compare
PfGW456L13_1192 -1.8 -2.4 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_1973 -1.8 -4.3 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_656 -1.8 -3.9 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_2857 -1.8 -1.6 ChlD component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_5006 -1.7 -2.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_2623 -1.7 -2.3 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_326 -1.7 -11.3 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
PfGW456L13_144 -1.7 -5.4 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_274 -1.7 -8.1 DamX, an inner membrane protein involved in bile resistance compare
PfGW456L13_1574 -1.7 -3.4 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_1834 -1.6 -7.4 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_2029 -1.6 -10.5 BarA sensory histidine kinase (= VarS = GacS) compare
PfGW456L13_952 -1.6 -5.0 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_4088 -1.6 -2.9 Transcriptional regulator, GntR family compare
PfGW456L13_4842 -1.6 -2.9 Translation elongation factor LepA compare
PfGW456L13_67 -1.5 -3.0 Cobalamin biosynthesis protein CobG compare
PfGW456L13_69 -1.5 -1.5 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
PfGW456L13_4545 -1.5 -1.9 Integral membrane protein compare
PfGW456L13_1985 -1.5 -3.9 Alginate biosynthesis transcriptional activator compare
PfGW456L13_4026 -1.5 -2.4 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_1637 -1.5 -5.0 Stringent starvation protein A compare
PfGW456L13_350 -1.5 -3.6 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_3997 -1.5 -4.5 hypothetical protein compare
PfGW456L13_2551 -1.5 -2.9 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_3577 -1.5 -2.3 hypothetical protein compare
PfGW456L13_4883 -1.4 -4.6 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
PfGW456L13_2776 -1.4 -1.8 Phage protein compare
PfGW456L13_1386 -1.3 -11.7 Sensor histidine kinase compare
PfGW456L13_3398 -1.3 -3.5 Transcriptional regulator, TetR family compare
PfGW456L13_757 -1.3 -1.5 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_4125 -1.3 -1.9 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_1813 -1.3 -6.3 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_4041 -1.3 -2.0 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_4882 -1.3 -2.7 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_4207 -1.3 -5.0 Periplasmic protease compare
PfGW456L13_68 -1.3 -2.3 hypothetical protein compare
PfGW456L13_5086 -1.3 -3.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_726 -1.3 -6.2 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_3260 -1.3 -1.4 hypothetical protein compare
PfGW456L13_2496 -1.3 -2.0 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_928 -1.2 -6.3 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
PfGW456L13_1842 -1.2 -6.2 Outer membrane porin, OprD family compare
PfGW456L13_2920 -1.2 -2.0 FIG00962345: hypothetical protein compare
PfGW456L13_347 -1.2 -6.2 Nitrogen regulation protein NR(I) compare
PfGW456L13_4668 -1.2 -3.8 RecA protein compare
PfGW456L13_327 -1.2 -3.2 hypothetical protein compare
PfGW456L13_4254 -1.2 -4.5 FIG00955360: hypothetical protein compare
PfGW456L13_3302 -1.2 -1.1 FIG00954674: hypothetical protein compare
PfGW456L13_5005 -1.2 -3.3 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_874 -1.2 -9.3 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_5060 -1.2 -3.3 Peptide chain release factor 3 compare
PfGW456L13_2553 -1.2 -5.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_567 -1.2 -7.2 Glycine cleavage system transcriptional activator compare
PfGW456L13_4805 -1.2 -8.5 Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) compare
PfGW456L13_355 -1.1 -3.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_151 -1.1 -2.6 HflC protein compare
PfGW456L13_2552 -1.1 -4.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_2237 -1.1 -1.7 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4992 -1.1 -8.6 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_4993 -1.1 -7.9 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
PfGW456L13_2763 -1.1 -1.9 putative tellurium resistance protein compare
PfGW456L13_2385 -1.1 -1.7 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
PfGW456L13_769 -1.1 -1.3 DNA-binding protein HU-alpha compare
PfGW456L13_1850 -1.1 -4.9 FIG000859: hypothetical protein YebC compare
PfGW456L13_4003 -1.1 -4.5 YjbG polysaccharide synthesis-related protein compare
PfGW456L13_3990 -1.1 -2.9 Response regulator receiver domain protein (CheY) compare
PfGW456L13_1011 -1.1 -1.4 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_140 -1.1 -2.6 FIG003573: hypothetical protein compare
PfGW456L13_282 -1.1 -7.7 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
PfGW456L13_427 -1.1 -1.1 Two-component system response regulator OmpR compare
PfGW456L13_3996 -1.1 -5.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
PfGW456L13_1525 -1.1 -5.9 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
PfGW456L13_4719 -1.0 -3.0 HesA/MoeB/ThiF family protein related to EC-YgdL compare
PfGW456L13_1356 -1.0 -4.2 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
PfGW456L13_3846 -1.0 -2.4 Predicted secretion system X FIG084745: hypothetical protein compare
PfGW456L13_2035 -1.0 -6.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_1984 -1.0 -1.3 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_4155 -1.0 -4.1 Spermidine synthase (EC 2.5.1.16) compare
PfGW456L13_4660 -1.0 -3.1 LysR family transcriptional regulator PA3398 compare
PfGW456L13_4236 -1.0 -1.4 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
PfGW456L13_4507 -1.0 -2.6 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_1226 -1.0 -7.6 S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A compare
PfGW456L13_3999 -1.0 -2.9 N-acetylmannosaminyltransferase (EC 2.4.1.187) compare
PfGW456L13_3936 -1.0 -4.0 Colicin V production protein compare
PfGW456L13_5048 -1.0 -2.2 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_3610 -1.0 -1.7 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_848 -1.0 -2.4 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
PfGW456L13_2856 -1.0 -3.0 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_2095 -1.0 -2.0 Ribonuclease E (EC 3.1.26.12) compare
PfGW456L13_1580 -1.0 -4.8 FIG140336: TPR domain protein compare
PfGW456L13_5152 -1.0 -3.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
PfGW456L13_3835 -1.0 -2.8 FIG00957304: hypothetical protein compare
PfGW456L13_3859 -1.0 -2.5 Nicotinamidase family protein YcaC compare
PfGW456L13_1169 -1.0 -6.3 Coenzyme PQQ synthesis protein F compare
PfGW456L13_753 -1.0 -7.1 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
PfGW456L13_66 -1.0 -1.0 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
PfGW456L13_3994 -1.0 -6.0 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
PfGW456L13_4004 -1.0 -7.6 YjbH outer membrane lipoprotein compare
PfGW456L13_152 -1.0 -2.5 HflK protein compare
PfGW456L13_1997 -0.9 -3.0 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_4022 -0.9 -2.4 FIG00953243: hypothetical protein compare
PfGW456L13_4238 -0.9 -3.4 Cobyric acid synthase (EC 6.3.5.10) compare
PfGW456L13_4836 -0.9 -5.4 Transglycosylase, Slt family compare
PfGW456L13_2933 -0.9 -1.9 LysR family transcriptional regulator STM2281 compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source L-Histidine in Pseudomonas fluorescens GW456-L13

For nitrogen source L-Histidine across organisms