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Experiment set3IT043 for
Ralstonia solanacearum PSI07
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M63_quarter_strength
200 most detrimental genes:
gene
name
fitness
t score
description
RPSI07
_RS18140
+4.2
24.1
RNA polymerase sigma factor RpoS
compare
RPSI07
_RS12335
+4.0
33.9
type II toxin-antitoxin system HipA family toxin
compare
RPSI07
_RS18145
+3.6
6.6
LysM peptidoglycan-binding domain-containing protein
compare
RPSI07
_RS23775
+2.6
1.2
transmembrane anti-sigma factor
compare
RPSI07
_RS17025
+2.5
2.3
RNA methyltransferase
compare
RPSI07
_RS12000
+2.4
15.1
polynucleotide adenylyltransferase PcnB
compare
RPSI07
_RS10675
+2.4
1.1
hypothetical protein
compare
RPSI07
_RS11495
+2.3
9.7
hybrid sensor histidine kinase/response regulator
compare
RPSI07
_RS10225
+2.3
3.9
hypothetical protein
compare
RPSI07
_RS15770
+2.3
2.3
DUF1488 domain-containing protein
compare
RPSI07
_RS08725
+2.2
2.3
septal ring lytic transglycosylase RlpA family protein
compare
RPSI07
_RS15840
+2.2
6.3
phasin; polyhydroxyalkanoate synthesis and granule formation regulator/factor
compare
RPSI07
_RS11500
+2.2
13.9
two-component sensor histidine kinase
compare
RPSI07
_RS11030
+2.2
1.7
NUDIX domain-containing protein
compare
RPSI07
_RS04095
+2.2
3.4
DUF2946 domain-containing protein
compare
RPSI07
_RS00780
+2.1
5.8
MarR family transcriptional regulator
compare
RPSI07
_RS10330
+2.1
4.5
tripartite tricarboxylate transporter substrate binding protein
compare
RPSI07
_RS15930
+2.1
1.9
potassium transporter Kup
compare
RPSI07
_RS18455
+2.1
1.8
cupin domain-containing protein
compare
RPSI07
_RS00395
+2.0
1.7
2-methylcitrate synthase
compare
RPSI07
_RS03875
+2.0
2.2
hypothetical protein
compare
RPSI07
_RS17995
+2.0
1.9
FAD-dependent oxidoreductase
compare
RPSI07
_RS02825
+2.0
2.2
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
compare
RPSI07
_RS13910
+1.9
1.5
hypothetical protein
compare
RPSI07
_RS22435
+1.9
5.1
phosphoenolpyruvate--protein phosphotransferase
compare
RPSI07
_RS22630
+1.9
2.5
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
compare
RPSI07
_RS17760
+1.8
2.9
cell division protein ZapE
compare
RPSI07
_RS14910
+1.8
1.1
hypothetical protein
compare
RPSI07
_RS11570
+1.8
3.3
FMN-binding glutamate synthase family protein
compare
RPSI07
_RS18515
+1.8
1.0
thiol-disulfide oxidoreductase DCC family protein
compare
RPSI07
_RS22735
+1.8
6.1
sensor histidine kinase
compare
RPSI07
_RS19110
+1.7
1.3
hypothetical protein
compare
RPSI07
_RS14555
+1.7
1.5
glyoxalase
compare
RPSI07
_RS12200
+1.7
2.2
3-hydroxyacyl-CoA dehydrogenase
compare
RPSI07
_RS17240
+1.7
3.5
ABC transporter ATP-binding protein
compare
RPSI07
_RS15115
+1.7
5.3
hypothetical protein
compare
RPSI07
_RS13620
+1.6
4.6
glycosyl transferase
compare
RPSI07
_RS18210
+1.6
1.5
antibiotic biosynthesis monooxygenase
compare
RPSI07
_RS18950
+1.6
2.9
beta-N-acetylhexosaminidase
compare
RPSI07
_RS20675
+1.6
1.6
response regulator
compare
RPSI07
_RS17230
+1.6
3.9
glutathione ABC transporter permease GsiC
compare
RPSI07
_RS01905
+1.6
1.2
hypothetical protein
compare
RPSI07
_RS04135
+1.6
0.8
arsenate reductase ArsC
compare
RPSI07
_RS11505
+1.6
7.7
class I SAM-dependent methyltransferase
compare
RPSI07
_RS22170
+1.6
6.1
GTPase
compare
RPSI07
_RS02100
+1.5
2.3
chemotaxis protein CheV
compare
RPSI07
_RS24415
+1.5
2.3
hypothetical protein
compare
RPSI07
_RS11440
+1.5
3.7
LysR family transcriptional regulator
compare
RPSI07
_RS04530
+1.5
9.4
hypothetical protein
compare
RPSI07
_RS20335
+1.4
1.9
transcriptional regulator NrdR
compare
RPSI07
_RS07395
+1.4
6.1
amino acid ABC transporter permease
compare
RPSI07
_RS14635
+1.4
1.6
hypothetical protein
compare
RPSI07
_RS07330
+1.4
1.5
DUF3293 domain-containing protein
compare
RPSI07
_RS19630
+1.4
1.4
methionine ABC transporter ATP-binding protein
compare
RPSI07
_RS16540
+1.4
1.5
hypothetical protein
compare
RPSI07
_RS22825
+1.4
1.5
HAD family phosphatase
compare
RPSI07
_RS17710
+1.4
3.2
hypothetical protein
compare
RPSI07
_RS11795
+1.3
2.3
CidA/LrgA family protein
compare
RPSI07
_RS00230
+1.3
2.9
enoyl-CoA hydratase
compare
RPSI07
_RS24260
+1.3
0.6
2,5-didehydrogluconate reductase
compare
RPSI07
_RS22280
+1.3
1.2
ABC transporter ATP-binding protein
compare
RPSI07
_RS08250
+1.3
2.3
HU family DNA-binding protein
compare
RPSI07
_RS14610
+1.3
2.8
ABC transporter substrate-binding protein
compare
RPSI07
_RS24915
+1.3
2.2
hypothetical protein
compare
RPSI07
_RS08735
+1.3
2.3
YraN family protein
compare
RPSI07
_RS15685
+1.3
6.2
bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
compare
RPSI07
_RS17735
+1.3
4.8
cytochrome-c oxidase, cbb3-type subunit II
compare
RPSI07
_RS20045
+1.3
2.0
RNA-binding protein
compare
RPSI07
_RS20020
+1.2
2.7
DUF2214 domain-containing protein
compare
RPSI07
_RS18330
+1.2
3.2
ABC transporter permease
compare
RPSI07
_RS12905
+1.2
0.9
cobalamin-binding protein
compare
RPSI07
_RS10005
+1.2
3.1
DUF2300 domain-containing protein
compare
RPSI07
_RS20310
+1.2
1.3
protein TolR
compare
RPSI07
_RS19650
+1.2
0.7
competence protein ComEA
compare
RPSI07
_RS13120
+1.2
1.7
cytochrome B oxidoreductase
compare
RPSI07
_RS11350
+1.2
2.3
ribonuclease N
compare
RPSI07
_RS08700
+1.2
1.2
hypothetical protein
compare
RPSI07
_RS11955
+1.2
1.3
nucleoside diphosphate kinase regulator
compare
RPSI07
_RS12025
+1.2
1.0
hypothetical protein
compare
RPSI07
_RS17650
+1.2
2.3
RND transporter
compare
RPSI07
_RS00460
+1.2
1.6
hypothetical protein
compare
RPSI07
_RS24535
+1.2
4.5
hypothetical protein
compare
RPSI07
_RS17640
+1.1
1.5
translational GTPase TypA
compare
RPSI07
_RS12260
+1.1
1.7
hypothetical protein
compare
RPSI07
_RS23860
+1.1
1.3
DUF3617 domain-containing protein
compare
RPSI07
_RS10220
+1.1
2.8
c-type cytochrome biogenesis protein CcsB
compare
RPSI07
_RS19065
+1.1
2.6
S-adenosylmethionine-dependent methyltransferase
compare
RPSI07
_RS10995
+1.1
2.2
peroxiredoxin
compare
RPSI07
_RS07405
+1.1
4.9
helix-turn-helix transcriptional regulator
compare
RPSI07
_RS21565
+1.1
2.2
histidine phosphatase family protein
compare
RPSI07
_RS18405
+1.1
1.7
RNA methyltransferase
compare
RPSI07
_RS14905
+1.1
2.0
baseplate assembly protein
compare
RPSI07
_RS17960
+1.1
3.4
MurR/RpiR family transcriptional regulator
compare
RPSI07
_RS07880
+1.1
2.6
hypothetical protein
compare
RPSI07
_RS17815
+1.1
0.7
nitrogen regulation protein NR(I)
compare
RPSI07
_RS01395
+1.1
2.0
flagellar basal body rod protein FlgC
compare
RPSI07
_RS14605
+1.0
1.8
hypothetical protein
compare
RPSI07
_RS23650
+1.0
1.3
rod shape-determining protein MreC
compare
RPSI07
_RS23450
+1.0
2.1
hypothetical protein
compare
RPSI07
_RS07400
+1.0
1.5
arginase
compare
RPSI07
_RS19480
+1.0
0.6
hypothetical protein
compare
RPSI07
_RS15750
+1.0
1.8
hypothetical protein
compare
RPSI07
_RS16120
+1.0
2.2
trigger factor
compare
RPSI07
_RS20215
+1.0
0.6
DUF883 domain-containing protein
compare
RPSI07
_RS15775
+1.0
2.1
4-hydroxy-2-oxoheptanedioate aldolase
compare
RPSI07
_RS07385
+1.0
1.3
amino acid ABC transporter substrate-binding protein
compare
RPSI07
_RS18115
+1.0
0.7
23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN
compare
RPSI07
_RS04995
+1.0
1.4
antibiotic biosynthesis monooxygenase
compare
RPSI07
_RS05560
+1.0
2.1
GGDEF domain-containing protein
compare
RPSI07
_RS13475
+1.0
1.4
TIGR00730 family Rossman fold protein
compare
RPSI07
_RS13980
+1.0
1.4
hypothetical protein
compare
RPSI07
_RS19625
+1.0
1.5
ABC transporter permease
compare
RPSI07
_RS22720
+1.0
3.9
DNA-binding response regulator
compare
RPSI07
_RS21320
+1.0
1.4
serine/threonine protein kinase
compare
RPSI07
_RS00995
+1.0
1.4
PadR family transcriptional regulator
compare
RPSI07
_RS21370
+1.0
1.2
NAD(P)/FAD-dependent oxidoreductase
compare
RPSI07
_RS17915
+1.0
2.4
rhizopine-binding protein
compare
RPSI07
_RS18890
+1.0
2.3
GlsB/YeaQ/YmgE family stress response membrane protein
compare
RPSI07
_RS16670
+1.0
3.9
peptide biosynthesis thioesterase
compare
RPSI07
_RS08380
+1.0
1.3
LysR family transcriptional regulator
compare
RPSI07
_RS10745
+1.0
1.8
DUF1311 domain-containing protein
compare
RPSI07
_RS08005
+1.0
2.4
cellobiose phosphorylase
compare
RPSI07
_RS16080
+1.0
3.5
DUF1800 domain-containing protein
compare
RPSI07
_RS03855
+1.0
1.6
hypothetical protein
compare
RPSI07
_RS22625
+1.0
0.9
SPOR domain-containing protein
compare
RPSI07
_RS15625
+1.0
2.8
CBS domain-containing protein
compare
RPSI07
_RS03430
+0.9
2.0
TetR family transcriptional regulator
compare
RPSI07
_RS04820
+0.9
0.4
Hpt domain-containing protein
compare
RPSI07
_RS22605
+0.9
2.2
ABC transporter ATP-binding protein
compare
RPSI07
_RS21120
+0.9
2.3
GDSL family lipase
compare
RPSI07
_RS10615
+0.9
1.9
hypothetical protein
compare
RPSI07
_RS00075
+0.9
2.3
branched-chain amino acid ABC transporter permease
compare
RPSI07
_RS22215
+0.9
2.1
DUF4124 domain-containing protein
compare
RPSI07
_RS11265
+0.9
1.2
TlpA family protein disulfide reductase
compare
RPSI07
_RS19735
+0.9
1.6
glycine zipper 2TM domain-containing protein
compare
RPSI07
_RS02745
+0.9
0.5
aspartate dehydrogenase
compare
RPSI07
_RS02030
+0.9
3.6
TolC family protein
compare
RPSI07
_RS13405
+0.9
1.7
ABC transporter ATP-binding protein
compare
RPSI07
_RS06200
+0.9
1.4
type II 3-dehydroquinate dehydratase
compare
RPSI07
_RS14520
+0.9
1.5
isoprenylcysteine carboxylmethyltransferase family protein
compare
RPSI07
_RS10555
+0.9
0.7
FecR family protein
compare
RPSI07
_RS18040
+0.9
1.4
phosphoribosyltransferase
compare
RPSI07
_RS19485
+0.9
1.1
membrane protein
compare
RPSI07
_RS15225
+0.9
2.1
SAM-dependent methyltransferase
compare
RPSI07
_RS10570
+0.9
1.9
cytochrome o ubiquinol oxidase subunit I
compare
RPSI07
_RS01040
+0.9
3.9
N-acetyltransferase
compare
RPSI07
_RS06505
+0.9
1.9
hypothetical protein
compare
RPSI07
_RS13715
+0.9
3.6
quinone oxidoreductase
compare
RPSI07
_RS21050
+0.9
3.2
MarR family transcriptional regulator
compare
RPSI07
_RS00540
+0.9
1.5
type VI secretion protein
compare
RPSI07
_RS00985
+0.9
2.6
hypothetical protein
compare
RPSI07
_RS21290
+0.9
0.9
hypothetical protein
compare
RPSI07
_RS05080
+0.9
2.2
membrane protein
compare
RPSI07
_RS13445
+0.9
0.7
UTP--glucose-1-phosphate uridylyltransferase
compare
RPSI07
_RS01660
+0.9
2.0
transcriptional regulator
compare
RPSI07
_RS13085
+0.9
1.0
membrane protein
compare
RPSI07
_RS17850
+0.9
1.0
sterol desaturase family protein
compare
RPSI07
_RS00380
+0.9
1.5
hypothetical protein
compare
RPSI07
_RS24025
+0.9
3.5
hypothetical protein
compare
RPSI07
_RS15970
+0.9
1.4
RluA family pseudouridine synthase
compare
RPSI07
_RS24825
+0.9
1.4
hypothetical protein
compare
RPSI07
_RS14305
+0.9
0.5
polyribonucleotide nucleotidyltransferase
compare
RPSI07
_RS01420
+0.9
1.0
flagellar L-ring protein FlgH
compare
RPSI07
_RS11490
+0.9
2.4
response regulator
compare
RPSI07
_RS20875
+0.8
3.2
nitrile hydratase subunit beta
compare
RPSI07
_RS23225
+0.8
3.3
hypothetical protein
compare
RPSI07
_RS10920
+0.8
0.7
division/cell wall cluster transcriptional repressor MraZ
compare
RPSI07
_RS01310
+0.8
1.3
Cd(II)/Pb(II)-responsive transcriptional regulator
compare
RPSI07
_RS09140
+0.8
2.1
DUF1484 domain-containing protein
compare
RPSI07
_RS20435
+0.8
2.7
NAD-dependent succinate-semialdehyde dehydrogenase
compare
RPSI07
_RS19270
+0.8
1.7
malonic semialdehyde reductase
compare
RPSI07
_RS19335
+0.8
2.2
DNA-deoxyinosine glycosylase
compare
RPSI07
_RS07100
+0.8
3.2
virulence factor family protein
compare
RPSI07
_RS03550
+0.8
1.9
transcriptional regulator
compare
RPSI07
_RS15190
+0.8
0.7
DUF1488 domain-containing protein
compare
RPSI07
_RS19405
+0.8
1.5
chromate transporter
compare
RPSI07
_RS17225
+0.8
2.7
glutathione ABC transporter permease GsiD
compare
RPSI07
_RS17660
+0.8
2.4
MFS transporter
compare
RPSI07
_RS21360
+0.8
2.0
DUF1571 domain-containing protein
compare
RPSI07
_RS24940
+0.8
1.3
hypothetical protein
compare
RPSI07
_RS18885
+0.8
2.9
FadR family transcriptional regulator
compare
RPSI07
_RS19350
+0.8
0.8
alanyl-tRNA editing protein
compare
RPSI07
_RS22865
+0.8
1.4
type II toxin-antitoxin system Phd/YefM family antitoxin
compare
RPSI07
_RS11130
+0.8
1.6
hypoxanthine-guanine phosphoribosyltransferase
compare
RPSI07
_RS08205
+0.8
2.3
23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ
compare
RPSI07
_RS12460
+0.8
2.6
hypothetical protein
compare
RPSI07
_RS00470
+0.8
3.9
GNAT family N-acetyltransferase
compare
RPSI07
_RS16935
+0.8
0.5
LysR family transcriptional regulator
compare
RPSI07
_RS10700
+0.8
3.3
PDZ domain-containing protein
compare
RPSI07
_RS17440
+0.8
1.3
FMN reductase (NADPH)
compare
RPSI07
_RS11980
+0.8
0.6
ABC transporter permease
compare
RPSI07
_RS01335
+0.8
0.6
organic hydroperoxide resistance protein
compare
RPSI07
_RS08950
+0.8
1.9
hypothetical protein
compare
RPSI07
_RS01460
+0.8
2.2
flagellar biosynthetic protein FliP
compare
RPSI07
_RS16290
+0.8
1.8
peptide-methionine (R)-S-oxide reductase
compare
RPSI07
_RS16215
+0.8
1.7
LysR family transcriptional regulator
compare
RPSI07
_RS14250
+0.8
1.3
RNA polymerase sigma factor
compare
RPSI07
_RS22370
+0.8
2.3
DUF2244 domain-containing protein
compare
RPSI07
_RS05900
+0.8
2.4
class II fumarate hydratase
compare
RPSI07
_RS15305
+0.8
2.4
phosphate ABC transporter, permease protein PstA
compare
Specific Phenotypes
For 6 genes in this experiment