Experiment set39IT050 for Pseudomonas putida KT2440

Compare to:

2-Methylbutanoic acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1650 +3.0 25.6 Sensor protein GacS compare
PP_1623 +3.0 13.4 RNA polymerase, sigma S (sigma 38) factor compare
PP_4099 +3.0 24.3 two-componenent system BarA/UvrY - regulatory subunit compare
PP_5145 +2.6 21.1 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0948 +2.4 9.8 Phosphocarrier protein HPr compare
PP_0232 +2.1 2.5 ATP-binding taurine transporter subunit compare
PP_0960 +1.7 7.9 phospholipid ABC transporter binding protein compare
PP_0345 +1.5 5.9 putative Heptose kinase WapP compare
PP_2889 +1.5 3.9 putative Transmembrane regulator PrtR compare
PP_4171 +1.4 8.8 conserved exported protein of unknown function compare
PP_0630 +1.4 1.8 DNA gyrase inhibitor YacG compare
PP_2403 +1.4 1.9 Chemotaxis protein CheY compare
PP_2633 +1.3 2.2 conserved protein of unknown function compare
PP_4271 +1.3 1.4 conserved protein of unknown function compare
PP_2163 +1.3 7.5 VacJ lipoprotein compare
PP_4937 +1.3 6.3 toluene tolerance protein compare
PP_5483 +1.2 1.2 conserved protein of unknown function compare
PP_0962 +1.2 3.8 toluene-tolerance protein compare
PP_4994 +1.2 3.7 conserved protein of unknown function compare
PP_1038 +1.2 1.2 conserved protein of unknown function compare
PP_3043 +1.1 1.9 conserved protein of unknown function compare
PP_0959 +1.1 3.6 phospholipid ABC transporter compare
PP_4373 +1.1 7.7 Transcriptional regulator FleQ compare
PP_4997 +1.1 1.6 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_4528 +1.1 1.2 conserved protein of unknown function compare
PP_0958 +1.1 6.1 phospholipid ABC transporter ATP-binding subunit compare
PP_0805 +1.1 7.0 Outer membrane efflux protein compare
PP_0961 +1.1 6.1 toluene tolerance protein compare
PP_0574 +1.0 7.2 DNA-binding response regulator, LuxR family compare
PP_4593 +1.0 1.1 conserved protein of unknown function compare
PP_3365 +1.0 1.1 Acetolactate synthase compare
PP_0806 +1.0 8.8 putative Surface adhesion protein compare
PP_5558 +0.9 3.1 putative transcriptional xre family of phage origin compare
PP_2330 +0.9 5.0 conserved protein of unknown function compare
PP_5248 +0.9 0.8 putative hydrolase compare
PP_1428 +0.9 2.9 Sigma factor AlgU negative regulatory protein compare
PP_3651 +0.9 6.5 Sensor histidine kinase/response regulator compare
PP_0803 +0.9 6.0 Protein secretion ABC efflux system, membrane fusion protein compare
PP_4789 +0.9 1.9 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_2700 +0.9 1.3 AhpC/TSA family protein compare
PP_0167 +0.9 8.1 Toxin secretion ATP-binding protein compare
PP_4262 +0.9 2.4 Cytochrome oxidase maturation protein, cbb3-type compare
PP_1781 +0.9 7.5 putative O-acyltransferase compare
PP_0852 +0.9 1.4 Transcriptional regulator, Cro/CI family compare
PP_4845 +0.9 2.0 putative Urea ABC transporter, ATP-binding protein compare
PP_2360 +0.8 2.0 putative type 1 pili subunit CsuA/B protein compare
PP_t29 +0.8 0.9 tRNA-Ala compare
PP_2550 +0.8 1.5 putative transcriptional regulatory protein compare
PP_1322 +0.8 1.2 putative Lipoprotein compare
PP_4065 +0.8 4.1 methylcrotonyl-CoA carboxylase biotin-containing subunit beta compare
PP_5093 +0.8 0.5 twitching motility protein compare
PP_3840 +0.8 1.7 conserved protein of unknown function compare
PP_0166 +0.8 6.2 HlyD family secretion protein compare
PP_0963 +0.8 1.3 putative BolA family protein compare
PP_1055 +0.8 0.7 Type II secretion pathway protein GspN compare
PP_1113 +0.8 5.7 Pyridoxal-phosphate dependent enzyme family protein compare
PP_5441 +0.8 2.0 protein of unknown function compare
PP_4519 +0.8 6.1 Agglutination protein compare
PP_0168 +0.8 7.1 putative surface adhesion protein compare
PP_2785 +0.8 2.3 conserved exported protein of unknown function compare
PP_4581 +0.8 1.5 putative amidotransferase compare
PP_0804 +0.8 3.9 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_5546 +0.8 1.1 conserved protein of unknown function compare
PP_0839 +0.8 1.9 tRNA Cm32/Um32 methyltransferase compare
PP_2127 +0.8 2.6 Sensor histidine kinase compare
PP_1137 +0.8 3.4 high-affinity branched-chain amino acid transporter, ATP binding compare
PP_0834 +0.8 1.4 Sec translocation complex subunit YajC compare
PP_1733 +0.8 1.5 membrane ATPase of the MinC-MinD-MinE system compare
PP_2640 +0.8 2.0 Acetyltransferase, GNAT family compare
PP_4156 +0.8 1.1 Transcriptional regulator, LysR family compare
PP_5628 +0.8 2.6 conserved protein of unknown function compare
PP_0781 +0.8 1.2 conserved protein of unknown function compare
PP_0001 +0.8 1.0 probable chromosome-partitioning protein compare
PP_2379 +0.8 4.2 putative cytochrome oxidase biogenesis protein compare
PP_2309 +0.8 0.8 conserved protein of unknown function compare
PP_0666 +0.8 1.7 conserved protein of unknown function compare
PP_2650 +0.8 1.4 putative 4-hydroxybutyrate dehydrogenase compare
PP_3825 +0.7 1.9 conserved protein of unknown function compare
PP_2229 +0.7 2.4 putative K(+)/H(+) antiporter subunit C compare
PP_5241 +0.7 1.3 DNA-binding response regulator, LuxR family compare
PP_4710 +0.7 4.9 tRNA pseudouridine 55 synthase compare
PP_2331 +0.7 3.7 conserved membrane protein of unknown function compare
PP_4340 +0.7 1.8 response regulator for chemotactic signal transduction compare
PP_0058 +0.7 6.3 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
PP_1662 +0.7 2.8 conserved protein of unknown function compare
PP_1325 +0.7 3.3 putative lipoprotein compare
PP_3048 +0.7 1.0 conserved protein of unknown function compare
PP_5557 +0.7 1.9 protein of unknown function compare
PP_5471 +0.7 0.9 putative response regulator receiver protein compare
PP_4199 +0.7 0.8 putative Lipoprotein compare
PP_1876 +0.7 1.1 putative ATP/GTP-binding protein of the AAA+ family compare
PP_0513 +0.7 0.7 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP compare
PP_4273 +0.7 0.6 Transcriptional regulator, MerR family compare
PP_2122 +0.7 1.8 molybdenum cofactor biosynthesis protein B compare
PP_1482 +0.7 1.6 polyamine ABC transporter, permease protein compare
PP_2900 +0.7 1.2 conserved protein of unknown function compare
PP_4629 +0.6 3.0 Sensory box protein compare
PP_4268 +0.6 0.9 nucleoid-associated broad specificity regulator compare
PP_4196 +0.6 0.9 conserved exported protein of unknown function compare
PP_1840 +0.6 3.4 conserved protein of unknown function compare
PP_5475 +0.6 1.0 conserved protein of unknown function compare
PP_2726 +0.6 1.7 conserved membrane protein of unknown function compare
PP_5008 +0.6 0.6 Poly granule-associated protein compare
PP_2075 +0.6 2.9 conserved membrane protein of unknown function compare
PP_0760 +0.6 2.0 conserved membrane protein of unknown function compare
PP_3392 +0.6 0.4 conserved protein of unknown function compare
PP_3245 +0.6 0.6 conserved protein of unknown function compare
PP_3400 +0.6 2.1 alpha-ketoglutarate- and Fe(II)-dependent dioxygenase compare
PP_2526 +0.6 1.9 conserved membrane protein of unknown function compare
PP_2105 +0.6 2.0 conserved protein of unknown function compare
PP_2318 +0.6 2.8 acyl-CoA thioesterase I/protease I/lysophospholipase L1 compare
PP_3908 +0.6 1.4 conserved protein of unknown function compare
PP_5429 +0.6 3.8 protein of unknown function compare
PP_3831 +0.6 2.4 conserved protein of unknown function compare
PP_3625 +0.6 2.2 Transporter, LysE family compare
PP_3512 +0.6 1.6 conserved membrane protein of unknown function compare
PP_5191 +0.6 1.4 conserved exported protein of unknown function compare
PP_0936 +0.6 3.2 septum formation protein compare
PP_5569 +0.6 1.9 protein of unknown function of phage origin compare
PP_4844 +0.6 1.2 putative Urea ABC transporter, ATP-binding protein compare
PP_4173 +0.6 3.5 Sensor histidine kinase/response regulator compare
PP_4419 +0.6 1.8 transposase compare
PP_5730 +0.6 1.9 conserved protein of unknown function compare
PP_1692 +0.6 1.3 conserved protein of unknown function compare
PP_2857 +0.6 1.3 conserved exported protein of unknown function compare
PP_2883 +0.6 0.6 conserved protein of unknown function compare
PP_0628 +0.6 2.0 conserved protein of unknown function compare
PP_2882 +0.6 1.3 putative 2-hydroxychromene-2-carboxylate isomerase compare
PP_1265 +0.5 1.8 conserved protein of unknown function compare
PP_4301 +0.5 1.5 Pyruvate kinase compare
PP_5055 +0.5 2.1 Sulfurtransferase compare
PP_4200 +0.5 3.3 conserved exported protein of unknown function compare
PP_1521 +0.5 2.1 conserved protein of unknown function compare
PP_1829 +0.5 0.8 Hydrolase, alpha/beta fold family compare
PP_1556 +0.5 0.9 conserved protein of unknown function compare
PP_0758 +0.5 1.9 conserved protein of unknown function compare
PP_2409 +0.5 1.4 cobalt-zinc-cadmium resistance protein compare
PP_0591 +0.5 2.0 Adenine deaminase compare
PP_1632 +0.5 0.7 conserved protein of unknown function compare
PP_1513 +0.5 1.2 Ribosomal RNA small subunit methyltransferase J compare
PP_3942 +0.5 2.1 maleate isomerase compare
PP_3294 +0.5 1.3 Universal stress protein family compare
PP_2387 +0.5 0.7 conserved protein of unknown function compare
PP_4331 +0.5 3.2 conserved protein of unknown function compare
PP_3650 +0.5 3.0 NUDIX hydrolase compare
PP_3098 +0.5 0.9 conserved protein of unknown function compare
PP_0411 +0.5 1.6 Polyamine ABC transporter, ATP-binding protein compare
PP_2672 +0.5 1.8 Transcriptional activator protein ExaE compare
PP_0755 +0.5 1.6 conserved protein of unknown function compare
PP_5582 +0.5 0.5 conserved protein of unknown function compare
PP_2291 +0.5 1.1 conserved protein of unknown function compare
PP_1605 +0.5 1.4 Ribonuclease HII compare
PP_0063 +0.5 1.7 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_4870 +0.5 1.1 Azurin compare
PP_5265 +0.5 2.1 Xanthine phosphoribosyltransferase compare
PP_1935 +0.5 1.3 Transcriptional regulator, Cro/CI family compare
PP_1236 +0.5 1.9 putative Glycine cleavage system transcriptional repressor compare
PP_1318 +0.5 2.5 Cytochrome b compare
PP_1998 +0.5 2.4 putative cell division protein compare
PP_2457 +0.5 1.9 DNA-binding transcriptional repressor compare
PP_3841 +0.5 2.5 Transcriptional regulator, MerR family compare
PP_4825 +0.5 2.5 Membrane protein, MarC family compare
PP_2878 +0.5 0.5 conserved protein of unknown function compare
PP_0214 +0.5 2.3 4-aminobutyrate aminotransferase compare
PP_3880 +0.5 0.6 conserved exported protein of unknown function compare
PP_1598 +0.5 1.4 regulatory intramembrane protein RIP zinc protease compare
PP_2847 +0.5 0.6 Urease accessory protein UreJ compare
PP_4254 +0.5 0.3 conserved protein of unknown function compare
PP_1630 +0.5 2.0 Regulatory protein RecX compare
PP_4981 +0.5 1.4 polyisoprene-binding protein, acidic stress response factor compare
PP_2305 +0.5 2.2 conserved protein of unknown function compare
PP_5689 +0.5 1.3 conserved protein of unknown function compare
PP_5486 +0.5 1.5 conserved protein of unknown function compare
PP_0575 +0.5 1.6 conserved membrane protein of unknown function compare
PP_1185 +0.5 1.9 Outer membrane protein H1 compare
PP_4760 +0.5 1.7 Alcohol dehydrogenase, zinc-containing compare
PP_4100 +0.5 2.0 Transcriptional regulator, Cro/CI family compare
PP_1757 +0.5 1.2 DNA-binding transcriptional dual regulator compare
PP_0133 +0.5 3.2 Alginate biosynthesis transcriptional regulatory protein AlgB compare
PP_1898 +0.5 0.9 MotA/TolQ/ExbB proton channel family protein compare
PP_5322 +0.5 1.9 putative metal ion transporter compare
PP_5686 +0.5 0.9 protein of unknown function compare
PP_3488 +0.5 1.9 Sco1/SenC family protein compare
PP_4892 +0.5 2.5 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_3923 +0.5 1.6 Phosphoglycerate mutase compare
PP_3206 +0.5 2.1 conserved protein of unknown function compare
PP_0304 +0.5 2.0 Carnitine uptake ABC transporter, periplasmic component compare
PP_0246 +0.5 1.0 two-component system DNA-binding response transcriptional dual regulator compare
PP_3874 +0.5 0.9 conserved protein of unknown function compare
PP_2363 +0.5 3.3 conserved protein of unknown function compare
PP_5635 +0.5 2.1 conserved protein of unknown function compare
PP_5667 +0.5 1.3 putative microcin B17-like-processing protein, McbC family compare
PP_5603 +0.5 1.7 putative FAD dependent oxidoreductase compare
PP_2866 +0.5 1.3 FMN-dependent NADH-azoreductase 1 compare
PP_2846 +0.4 1.4 urease accessory protein compare
PP_2611 +0.4 1.8 membrane protein of unknown function compare
PP_2777 +0.4 1.7 putative Acyl carrier protein compare
PP_5063 +0.4 1.6 betaine aldehyde dehydrogenase, NAD-dependent compare
PP_1396 +0.4 1.4 conserved protein of unknown function compare
PP_2503 +0.4 1.3 putative 3-oxoacyl-(Acyl-carrier-protein) reductase compare


Specific Phenotypes

For 10 genes in this experiment

For carbon source 2-Methylbutanoic acid in Pseudomonas putida KT2440

For carbon source 2-Methylbutanoic acid across organisms