Experiment set39IT049 for Pseudomonas putida KT2440

Compare to:

2-Methylbutanoic acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1650 +3.4 29.6 Sensor protein GacS compare
PP_4099 +3.4 29.4 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1623 +2.9 16.1 RNA polymerase, sigma S (sigma 38) factor compare
PP_5145 +2.7 22.5 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0948 +2.7 11.5 Phosphocarrier protein HPr compare
PP_2889 +2.1 4.9 putative Transmembrane regulator PrtR compare
PP_t12 +1.6 1.2 tRNA-Thr compare
PP_0959 +1.6 5.7 phospholipid ABC transporter compare
PP_4171 +1.5 9.0 conserved exported protein of unknown function compare
PP_0960 +1.5 8.8 phospholipid ABC transporter binding protein compare
PP_4994 +1.4 4.8 conserved protein of unknown function compare
PP_0345 +1.4 4.1 putative Heptose kinase WapP compare
PP_0962 +1.4 5.1 toluene-tolerance protein compare
PP_0804 +1.3 6.8 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_5093 +1.3 0.8 twitching motility protein compare
PP_4937 +1.3 8.9 toluene tolerance protein compare
PP_2163 +1.2 7.5 VacJ lipoprotein compare
PP_0961 +1.2 7.4 toluene tolerance protein compare
PP_0806 +1.2 10.7 putative Surface adhesion protein compare
PP_0574 +1.2 8.5 DNA-binding response regulator, LuxR family compare
PP_1729 +1.1 2.8 conserved protein of unknown function compare
PP_4373 +1.1 7.7 Transcriptional regulator FleQ compare
PP_3935 +1.1 2.9 conserved protein of unknown function compare
PP_5140 +1.0 2.4 Transcriptional regulator, MerR family compare
PP_4528 +1.0 0.8 conserved protein of unknown function compare
PP_0958 +1.0 6.0 phospholipid ABC transporter ATP-binding subunit compare
PP_2330 +1.0 4.9 conserved protein of unknown function compare
PP_0805 +1.0 5.8 Outer membrane efflux protein compare
PP_5441 +1.0 1.9 protein of unknown function compare
PP_1513 +1.0 2.3 Ribosomal RNA small subunit methyltransferase J compare
PP_1781 +1.0 7.9 putative O-acyltransferase compare
PP_0640 +1.0 2.3 conserved protein of unknown function compare
PP_5248 +1.0 0.6 putative hydrolase compare
PP_0167 +0.9 8.1 Toxin secretion ATP-binding protein compare
PP_2210 +0.9 2.5 LysR family transcriptional regulator compare
PP_0803 +0.9 4.8 Protein secretion ABC efflux system, membrane fusion protein compare
PP_0166 +0.9 7.0 HlyD family secretion protein compare
PP_5200 +0.9 5.5 proline aminopeptidase P II compare
PP_1912 +0.9 3.0 Phosphate acyltransferase compare
PP_5202 +0.9 1.2 putative cell division protein compare
PP_5475 +0.9 2.0 conserved protein of unknown function compare
PP_2568 +0.9 1.0 Ring-cleaving dioxygenase compare
PP_2581 +0.9 1.3 conserved protein of unknown function compare
PP_3043 +0.9 1.1 conserved protein of unknown function compare
PP_3541 +0.9 2.1 Transporter, MgtC family compare
PP_2379 +0.9 3.6 putative cytochrome oxidase biogenesis protein compare
PP_0891 +0.9 2.3 conserved exported protein of unknown function compare
PP_1113 +0.9 4.6 Pyridoxal-phosphate dependent enzyme family protein compare
PP_2331 +0.8 3.9 conserved membrane protein of unknown function compare
PP_5253 +0.8 2.1 Arylesterase compare
PP_1938 +0.8 1.7 conserved protein of unknown function compare
PP_4136 +0.8 0.6 Transcriptional regulator, LuxR family compare
PP_0852 +0.8 2.3 Transcriptional regulator, Cro/CI family compare
PP_4519 +0.8 6.5 Agglutination protein compare
PP_2053 +0.8 2.9 conserved protein of unknown function compare
PP_0616 +0.8 2.9 Branched-chain amino acid ABC transporter, ATP binding protein compare
PP_0168 +0.8 7.3 putative surface adhesion protein compare
PP_5055 +0.8 2.4 Sulfurtransferase compare
PP_2231 +0.8 2.0 putative permease of the drug/metabolite transporter (DMT) superfamily compare
PP_4817 +0.8 2.6 MaoC domain protein compare
PP_5274 +0.8 1.3 conserved protein of unknown function compare
PP_1646 +0.8 3.9 putative Thioredoxin compare
PP_4470 +0.8 1.7 putative transcriptional regulator (Arc domain-containing) compare
PP_2142 +0.8 1.8 Cell division inhibitor SulA compare
PP_1381 +0.8 1.6 4-carboxymuconolactone decarboxylase compare
PP_2229 +0.8 1.8 putative K(+)/H(+) antiporter subunit C compare
PP_4262 +0.8 1.7 Cytochrome oxidase maturation protein, cbb3-type compare
PP_3048 +0.7 0.9 conserved protein of unknown function compare
PP_0925 +0.7 2.7 conserved protein of unknown function compare
PP_5225 +0.7 0.8 frataxin compare
PP_2726 +0.7 2.4 conserved membrane protein of unknown function compare
PP_3012 +0.7 4.2 conserved protein of unknown function compare
PP_2880 +0.7 2.5 Transcriptional regulator, TetR family compare
PP_0058 +0.7 6.4 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
PP_3651 +0.7 5.3 Sensor histidine kinase/response regulator compare
PP_2373 +0.7 1.2 conserved protein of unknown function compare
PP_0973 +0.7 2.7 Nucleoid-associated protein PP_0973 compare
PP_5162 +0.7 2.9 conserved exported protein of unknown function compare
PP_5514 +0.7 2.7 conserved protein of unknown function compare
PP_4066 +0.7 1.8 methylglutaconyl-CoA hydratase compare
PP_2756 +0.7 2.2 conserved protein of unknown function compare
PP_1736 +0.7 2.4 conserved protein of unknown function compare
PP_5558 +0.7 1.4 putative transcriptional xre family of phage origin compare
PP_4556 +0.7 1.5 conserved protein of unknown function compare
PP_5448 +0.7 2.9 conserved protein of unknown function compare
PP_3831 +0.7 2.7 conserved protein of unknown function compare
PP_1808 +0.7 1.7 glucose-6-phosphate isomerase compare
PP_5546 +0.7 1.1 conserved protein of unknown function compare
PP_0536 +0.7 2.7 conserved protein of unknown function compare
PP_0007 +0.7 1.6 conserved hypothetical protein compare
PP_1396 +0.7 1.7 conserved protein of unknown function compare
PP_0643 +0.7 1.2 protein of unknown function compare
PP_5170 +0.7 2.6 sulfate ABC transporter, inner membrane subunit CysT compare
PP_5686 +0.6 2.6 protein of unknown function compare
PP_2878 +0.6 0.5 conserved protein of unknown function compare
PP_0165 +0.6 5.3 GGDEF domain protein compare
PP_4581 +0.6 1.2 putative amidotransferase compare
PP_4837 +0.6 1.5 conserved protein of unknown function compare
PP_2444 +0.6 2.8 Transcriptional regulator, LysR family compare
PP_0868 +0.6 2.4 ABC transporter ATP-binding subunit compare
PP_2144 +0.6 2.0 Transcriptional regulator, TetR family compare
PP_3835 +0.6 3.1 Sensory box histidine kinase compare
PP_2454 +0.6 2.8 ribose ABC transporter, periplasmic ribose-binding subunit compare
PP_4647 +0.6 2.3 transcriptional regulator, LuxR family compare
PP_5505 +0.6 1.0 conserved transmembrane protein of unknown function compare
PP_3638 +0.6 2.4 putative Acyl-CoA dehydrogenase compare
PP_5146 +0.6 2.8 RNA pyrophosphohydrolase compare
PP_1898 +0.6 1.4 MotA/TolQ/ExbB proton channel family protein compare
PP_4710 +0.6 4.0 tRNA pseudouridine 55 synthase compare
PP_5714 +0.6 2.0 conserved protein of unknown function compare
PP_4396 +0.6 1.6 conserved protein of unknown function compare
PP_3883 +0.6 0.8 putative Phage holin compare
PP_2309 +0.6 0.6 conserved protein of unknown function compare
PP_5293 +0.6 1.7 conserved protein of unknown function compare
PP_4786 +0.6 2.0 conserved protein of unknown function compare
PP_4094 +0.6 1.2 conserved protein of unknown function compare
PP_3368 +0.6 2.7 Major facilitator family transporter compare
PP_3546 +0.6 3.5 Sensory box histidine kinase/response regulator compare
PP_3773 +0.6 1.7 conserved protein of unknown function compare
PP_2341 +0.6 1.1 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_0228 +0.6 2.8 putative serine acetyltransferase compare
PP_0346 +0.6 3.2 putative Heptose kinase WapQ compare
PP_3531 +0.6 2.0 conserved exported protein of unknown function compare
PP_1404 +0.6 1.2 conserved protein of unknown function compare
PP_0505 +0.6 1.9 conserved protein of unknown function compare
PP_3018 +0.6 2.8 conserved protein of unknown function compare
PP_5059 +0.6 2.0 conserved exported protein of unknown function compare
PP_5735 +0.6 1.1 conserved hypothetical protein compare
PP_4551 +0.5 3.7 Hydrolase, alpha/beta fold family compare
PP_2455 +0.5 2.2 ribose ABC transporter - ATP-binding subunit compare
PP_4916 +0.5 1.3 putative esterase compare
PP_3339 +0.5 1.8 conserved exported protein of unknown function compare
PP_2023 +0.5 1.6 Glutathione S-transferase family protein compare
PP_0826 +0.5 2.4 phosphonate ABC transporter, permease protein compare
PP_5561 +0.5 1.8 conserved protein of unknown function compare
PP_t13 +0.5 0.7 tRNA-Lys compare
PP_5512 +0.5 2.3 protein of unknown function compare
PP_4570 +0.5 3.7 conserved protein of unknown function compare
PP_2457 +0.5 2.6 DNA-binding transcriptional repressor compare
PP_3519 +0.5 0.4 putative Lipoprotein compare
PP_1307 +0.5 2.8 AsnC family transcriptional regulator compare
PP_3307 +0.5 0.8 conserved protein of unknown function compare
PP_4285 +0.5 1.7 5-hydroxyisourate hydrolase compare
PP_2362 +0.5 3.9 putative usher protein compare
PP_1840 +0.5 2.7 conserved protein of unknown function compare
PP_3923 +0.5 2.2 Phosphoglycerate mutase compare
PP_5161 +0.5 1.8 putative lysophospholipase compare
PP_2511 +0.5 0.9 conserved protein of unknown function compare
PP_1652 +0.5 2.7 histidine kinase compare
PP_0126 +0.5 1.1 Cytochrome c4 compare
PP_1071 +0.5 1.9 glutamate / aspartate ABC transporter - periplasmic binding protein compare
PP_1439 +0.5 0.7 conserved exported protein of unknown function compare
PP_0330 +0.5 1.7 hypothetical protein compare
PP_1662 +0.5 1.7 conserved protein of unknown function compare
PP_3594 +0.5 2.0 L-lysine and D-lysine ABC transporter, permease component 1 (from data) compare
PP_4997 +0.5 0.6 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_4340 +0.5 1.6 response regulator for chemotactic signal transduction compare
PP_4018 +0.5 1.5 Acetyltransferase, GNAT family compare
PP_1112 +0.5 2.8 conserved membrane protein of unknown function compare
PP_1456 +0.5 2.0 conserved membrane protein of unknown function compare
PP_4409 +0.5 1.6 Site-specific recombinase, phage integrase family compare
PP_5025 +0.5 3.0 Glucans biosynthesis glucosyltransferase H compare
PP_2409 +0.5 1.5 cobalt-zinc-cadmium resistance protein compare
PP_2739 +0.5 3.1 putative Sensory box protein compare
PP_1640 +0.5 2.6 putative inner membrane protein of unknown function compare
PP_4828 +0.5 0.7 Precorrin-8X methylmutase compare
PP_4757 +0.5 3.0 D-glucarate dehydratase / L-idarate epimerase compare
PP_4789 +0.5 2.2 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_2361 +0.5 2.3 putative chaperone protein compare
PP_4180 +0.5 1.7 conserved protein of unknown function compare
PP_4892 +0.5 2.2 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex compare
PP_0594 +0.5 2.8 Transcriptional regulator, TetR family compare
PP_1111 +0.5 2.7 putative Synthetase compare
PP_2247 +0.5 1.7 putative Endoribonuclease compare
PP_4689 +0.5 1.5 Heme/hemin ABC transporter, periplasmic heme/hemin-binding protein compare
PP_0575 +0.5 1.9 conserved membrane protein of unknown function compare
PP_0703 +0.5 0.9 putative Transmembrane sensor compare
PP_2050 +0.5 2.0 conserved protein of unknown function compare
PP_3496 +0.5 2.0 Endoribonuclease L-PSP compare
PP_3924 +0.5 1.2 conserved protein of unknown function compare
PP_2577 +0.5 2.2 putative paraquat-inducible protein B (pqiB like) compare
PP_2363 +0.5 3.3 conserved protein of unknown function compare
PP_5500 +0.5 1.5 protein of unknown function compare
PP_0157 +0.5 2.8 transcriptional activator of gcdH, LysR family compare
PP_0632 +0.5 2.3 leader peptidase/N-methyltransferase compare
PP_4705 +0.5 1.7 Glyoxalase compare
PP_2836 +0.5 1.6 putative 2-keto-3-deoxyxylonate dehydratase compare
PP_1317 +0.5 1.7 Ubiquinol-cytochrome c reductase iron-sulfur subunit compare
PP_3019 +0.5 2.0 Carbon-nitrogen hydrolase family protein compare
PP_2526 +0.5 1.2 conserved membrane protein of unknown function compare
PP_0540 +0.5 2.0 conserved inner membrane protein compare
PP_0922 +0.5 1.9 conserved protein of unknown function compare
PP_4569 +0.5 1.2 conserved protein of unknown function compare
PP_5617 +0.5 1.5 conserved protein of unknown function compare
PP_1687 +0.5 2.4 conserved exported protein of unknown function compare
PP_2422 +0.5 1.2 conserved protein of unknown function compare
PP_4073 +0.5 0.7 conserved exported protein of unknown function compare
PP_5265 +0.5 1.5 Xanthine phosphoribosyltransferase compare
PP_4657 +0.5 1.4 zinc metalloprotease compare
PP_5365 +0.5 2.9 putative fatty acid methyltransferase compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source 2-Methylbutanoic acid in Pseudomonas putida KT2440

For carbon source 2-Methylbutanoic acid across organisms