Experiment set39IT048 for Pseudomonas putida KT2440

Compare to:

1,3-Hexanediol carbon source

200 most important genes:

  gene name fitness t score description  
PP_4723 -9.4 -26.9 Carbamoyl-phosphate synthase large chain compare
PP_4724 -9.2 -13.7 Carbamoyl-phosphate synthase small chain compare
PP_0691 -7.7 -12.3 Glutamate 5-kinase compare
PP_0293 -7.0 -4.5 Imidazole glycerol phosphate synthase subunit HisF compare
PP_4999 -6.3 -4.4 dihydroorotase-like protein compare
PP_3511 -6.3 -4.3 Branched-chain-amino-acid aminotransferase compare
PP_0967 -5.9 -5.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0787 -5.9 -4.1 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_4116 -5.9 -5.7 isocitrate lyase compare
PP_0422 -5.8 -4.0 Indole-3-glycerol phosphate synthase compare
PP_1995 -5.8 -4.0 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_3821 -5.8 -13.0 UTP-glucose-1-phosphate uridylyltransferase compare
PP_4565 -5.8 -8.9 Isocitrate dehydrogenase kinase/phosphatase compare
PP_1985 -5.8 -4.0 3-isopropylmalate dehydratase large subunit compare
PP_1088 -5.7 -5.6 Argininosuccinate synthase compare
PP_1988 -5.7 -3.9 3-isopropylmalate dehydrogenase compare
PP_0966 -5.7 -5.5 Histidinol dehydrogenase compare
PP_2327 -5.5 -6.6 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0356 -5.5 -3.8 malate synthase G compare
PP_4678 -5.5 -6.5 Ketol-acid reductoisomerase compare
PP_2001 -5.5 -7.5 O-succinylhomoserine sulfhydrylase compare
PP_0417 -5.2 -12.7 Anthranilate synthase component 1 compare
PP_4680 -5.2 -3.6 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5098 -5.2 -3.6 methionine biosynthesis protein MetW compare
PP_0763 -5.2 -13.5 Medium-chain-fatty-acid CoA ligase compare
PP_5097 -5.2 -9.3 homoserine O-acetyltransferase compare
PP_5659 -5.2 -3.5 protein of unknown function compare
PP_4890 -5.1 -3.5 ATP phosphoribosyltransferase regulatory subunit compare
PP_4364 -5.1 -6.1 putative Anti-sigma F factor antagonist compare
PP_4994 -5.0 -6.8 conserved protein of unknown function compare
PP_4700 -4.9 -3.4 pantothenate synthetase compare
PP_0767 -4.9 -14.4 Transcriptional regulator, LuxR family compare
PP_4909 -4.9 -8.8 phosphoserine phosphatase compare
PP_0965 -4.8 -9.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_0378 -4.8 -9.7 Pyrroloquinoline-quinone synthase compare
PP_5289 -4.7 -3.3 Acetylglutamate kinase compare
PP_2433 -4.7 -3.0 conserved protein of unknown function compare
PP_2903 -4.6 -3.0 peptidyl-prolyl cis-trans isomerase B (rotamase B) compare
PP_1079 -4.6 -6.8 Ornithine carbamoyltransferase compare
PP_4679 -4.5 -3.1 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_0289 -4.5 -8.1 Imidazoleglycerol-phosphate dehydratase compare
PP_5185 -4.5 -4.3 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_1986 -4.5 -3.1 3-isopropylmalate dehydratase small subunit compare
PP_0376 -4.3 -11.8 Coenzyme PQQ synthesis protein E compare
PP_5095 -4.3 -8.3 pyrroline-5-carboxylate reductase compare
PP_1778 -4.2 -4.1 Lipopolysaccharide ABC export system, permease protein compare
PP_1233 -4.2 -9.0 sulfurtransferase compare
PP_4058 -4.2 -11.4 1,4-alpha-glucan branching enzyme compare
PP_0421 -4.1 -7.7 Anthranilate phosphoribosyltransferase compare
PP_0381 -4.1 -7.9 Coenzyme PQQ synthesis protein F compare
PP_5104 -4.1 -10.3 thiazole synthase compare
PP_2371 -4.1 -4.0 Sulphite reductase hemoprotein, beta subunit compare
PP_2665 -4.1 -4.4 Glycerol metabolism activator compare
PP_1110 -4.0 -3.6 serine acetyltransferase compare
PP_0184 -3.9 -2.7 Argininosuccinate lyase compare
PP_3999 -3.9 -5.4 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_4940 -3.9 -4.7 Putative glycosyltransferase compare
PP_4699 -3.9 -3.8 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_4696 -3.8 -3.7 Nitrogen regulation protein NR(I) compare
PP_5155 -3.7 -6.1 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_1231 -3.7 -6.7 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_5717 -3.7 -3.2 conserved protein of unknown function compare
PP_0292 -3.7 -2.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_2137 -3.7 -4.0 beta-ketoadipyl CoA thiolase, beta component compare
PP_0368 -3.6 -9.9 putative Acyl-CoA dehydrogenase compare
PP_0082 -3.6 -2.5 tryptophan synthase alpha chain compare
PP_2675 -3.6 -5.8 Cytochrome c-type protein compare
PP_0083 -3.5 -2.4 tryptophan synthase beta chain compare
PP_0420 -3.5 -11.6 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_1493 -3.5 -4.1 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_1025 -3.4 -11.5 2-isopropylmalate synthase compare
PP_5128 -3.3 -5.5 Dihydroxy-acid dehydratase compare
PP_0377 -3.3 -1.7 coenzyme PQQ synthesis protein D compare
PP_4923 -3.3 -10.1 Outer membrane efflux protein compare
PP_1111 -3.3 -7.0 putative Synthetase compare
PP_4782 -3.3 -6.1 Phosphomethylpyrimidine kinase compare
PP_0379 -3.2 -9.3 Coenzyme PQQ synthesis protein B compare
PP_5015 -3.2 -5.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_1269 -3.2 -1.2 Universal stress protein family compare
PP_0290 -3.2 -7.8 Imidazole glycerol phosphate synthase subunit HisH compare
PP_1779 -3.2 -3.1 Lipopolysaccharide ABC export system, ATP-binding protein compare
PP_1109 -3.2 -10.2 Transcriptional regulator, GntR family compare
PP_2328 -3.1 -6.0 Phosphoadenosine phosphosulfate reductase compare
PP_2168 -3.1 -12.7 Transaldolase compare
PP_0735 -3.1 -1.7 molybdopterin-synthase adenylyltransferase compare
PP_5347 -3.0 -14.3 pyruvate carboxylase subunit A compare
PP_5748 -3.0 -2.5 cytochrome c heme lyase subunit compare
PP_1898 -3.0 -4.5 MotA/TolQ/ExbB proton channel family protein compare
PP_5014 -3.0 -2.0 Phosphoribosyl-AMP cyclohydrolase compare
PP_2136 -2.9 -4.5 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_5085 -2.9 -7.8 malic enzyme B compare
PP_0164 -2.9 -9.5 conserved protein of unknown function compare
PP_2217 -2.9 -5.8 enoyl-CoA hydratase compare
PP_1328 -2.9 -2.4 Protein MraZ compare
PP_5346 -2.8 -13.1 pyruvate carboxylase subunit B compare
PP_4342 -2.7 -1.9 flagellar synthesis regulator, putative ATPase compare
PP_2414 -2.7 -2.7 conserved exported protein of unknown function compare
PP_2000 -2.4 -2.3 amidophosphoribosyl transferase compare
PP_t12 -2.4 -0.9 tRNA-Thr compare
PP_2820 -2.4 -4.7 HTH-type transcriptional regulator nfxB compare
PP_5203 -2.3 -8.5 5-formyltetrahydrofolate cyclo-ligase compare
PP_5227 -2.3 -7.9 diaminopimelate decarboxylase compare
PP_3755 -2.2 -8.3 3-hydroxybutyryl-CoA dehydrogenase compare
PP_5348 -2.1 -9.5 Transcriptional regulator, LysR family compare
PP_0291 -2.1 -3.4 conserved protein of unknown function compare
PP_3484 -2.1 -3.5 Response regulator receiver protein compare
PP_5313 -2.1 -2.0 DNA-binding protein HU-alpha compare
PP_2302 -2.1 -5.4 DNA-binding, ATP-dependent protease compare
PP_1310 -2.1 -2.7 conserved hypothetical protein compare
PP_4122 -2.0 -1.4 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_1941 -2.0 -5.6 conserved protein of unknown function compare
PP_1654 -2.0 -1.4 cysteine synthase B compare
PP_0087 -2.0 -2.0 conserved exported protein of unknown function compare
PP_0362 -2.0 -10.0 Biotin synthase compare
PP_4004 -1.9 -4.0 DNA translocase FtsK compare
PP_4870 -1.9 -2.9 Azurin compare
PP_4938 -1.9 -9.1 putative Glycosyl transferase compare
PP_5008 -1.9 -1.3 Poly granule-associated protein compare
PP_1387 -1.9 -4.4 Probable HTH-type transcriptional regulator TtgR compare
PP_4922 -1.9 -7.5 Phosphomethylpyrimidine synthase compare
PP_2326 -1.8 -4.9 Universal stress protein compare
PP_1428 -1.8 -2.6 Sigma factor AlgU negative regulatory protein compare
PP_0248 -1.8 -11.1 Probable alpha-L-glutamate ligase compare
PP_1800 -1.8 -11.7 Oxidoreductase Rmd compare
PP_2029 -1.8 -2.0 von Willebrand factor type A domain protein compare
PP_4143 -1.8 -6.3 conserved protein of unknown function compare
PP_4695 -1.7 -6.8 Sensory box histidine kinase compare
PP_3241 -1.7 -0.9 conserved exported protein of unknown function compare
PP_4130 -1.7 -2.5 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_1217 -1.7 -1.1 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_1468 -1.6 -2.6 Tyrosine recombinase XerD compare
PP_4726 -1.6 -2.5 Chaperone protein DnaJ compare
PP_3359 -1.6 -1.9 putative Hydroxycinnamic acid degradation regulator compare
PP_1804 -1.6 -10.3 Glycosyl transferase WbpL compare
PP_1568 -1.6 -1.0 conserved protein of unknown function compare
PP_4320 -1.6 -4.5 cytochrome c-type biogenesis protein compare
PP_4943 -1.5 -1.1 putative Glycosyl transferase compare
PP_1303 -1.5 -7.3 Sulfate adenylyltransferase subunit 2 compare
PP_4363 -1.5 -6.7 Sensor histidine kinase/response regulator compare
PP_2087 -1.5 -2.0 CmpX protein compare
PP_1664 -1.5 -5.1 phosphoribosylglycinamide formyltransferase 1 compare
PP_2370 -1.5 -1.8 conserved protein of unknown function compare
PP_1742 -1.5 -1.9 conserved inner membrane protein of unknown function compare
PP_1801 -1.5 -10.8 Glycosyl transferase WbpY compare
PP_1430 -1.5 -7.8 putative periplasmic serine endoprotease DegP-like compare
PP_4793 -1.4 -2.4 conserved protein of unknown function compare
PP_0048 -1.4 -0.9 conserved protein of unknown function compare
PP_5456 -1.4 -0.7 conserved protein of unknown function compare
PP_0127 -1.4 -7.2 Thiol:disulfide interchange protein compare
PP_0914 -1.4 -7.6 GGDEF domain protein compare
PP_1802 -1.4 -10.9 glycosyl transferase compare
PP_4936 -1.4 -6.7 O-antigen polymerase compare
PP_0959 -1.4 -3.2 phospholipid ABC transporter compare
PP_1198 -1.4 -1.8 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_3105 -1.3 -1.8 conserved membrane protein of unknown function compare
PP_0961 -1.3 -7.2 toluene tolerance protein compare
PP_3481 -1.3 -1.8 conserved exported protein of unknown function compare
PP_5035 -1.3 -5.0 Histidine utilization repressor compare
PP_4895 -1.3 -2.3 tRNA dimethylallyltransferase compare
PP_1237 -1.3 -0.8 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_4136 -1.3 -0.7 Transcriptional regulator, LuxR family compare
PP_4247 -1.3 -0.9 Exonuclease compare
PP_3035 -1.3 -1.9 conserved protein of unknown function compare
PP_1719 -1.3 -7.9 Tail-specific protease prc compare
PP_0428 -1.3 -6.9 aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase compare
PP_5145 -1.3 -10.1 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_3731 -1.3 -6.4 Transcriptional regulator, TetR family compare
PP_1655 -1.2 -2.5 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_4505 -1.2 -4.3 Sensor histidine kinase compare
PP_1355 -1.2 -11.1 Muropeptide permease AmpG compare
PP_5146 -1.2 -6.9 RNA pyrophosphohydrolase compare
PP_0435 -1.2 -9.5 Peptidase, M23/M37 family compare
PP_0250 -1.2 -1.6 heat shock protein Hsp15 involved in ribosome recycling compare
PP_2513 -1.2 -2.8 4-oxalomesaconate tautomerase compare
PP_2145 -1.2 -7.8 beta-N-acetylglucosaminidase compare
PP_0126 -1.2 -2.8 Cytochrome c4 compare
PP_1319 -1.2 -5.8 Ubiquinol--cytochrome c reductase, cytochrome c1 compare
PP_0434 -1.2 -9.1 Anhydro-N-acetylmuramic acid kinase compare
PP_1780 -1.2 -10.2 putative mannosyltransferase compare
PP_2107 -1.2 -1.9 conserved protein of unknown function compare
PP_4824 -1.2 -4.0 Sensor histidine kinase/response regulator compare
PP_0001 -1.2 -0.8 probable chromosome-partitioning protein compare
PP_5508 -1.2 -0.7 conserved protein of unknown function compare
PP_1317 -1.2 -4.3 Ubiquinol-cytochrome c reductase iron-sulfur subunit compare
PP_3539 -1.2 -1.9 putative Transcriptional regulator compare
PP_0833 -1.2 -1.8 queuine tRNA-ribosyltransferase compare
PP_4150 -1.2 -3.5 microcin C transporter - ATP binding subunit compare
PP_4835 -1.2 -1.9 conserved exported protein of unknown function compare
PP_5230 -1.2 -1.6 Tyrosine recombinase XerC compare
PP_4977 -1.2 -6.8 5,10-methylenetetrahydrofolate reductase compare
PP_1776 -1.1 -9.6 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase compare
PP_0958 -1.1 -6.0 phospholipid ABC transporter ATP-binding subunit compare
PP_3637 -1.1 -2.8 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_2163 -1.1 -5.3 VacJ lipoprotein compare
PP_1679 -1.1 -2.6 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_1862 -1.1 -2.5 conserved membrane protein of unknown function compare
PP_4131 -1.1 -2.0 NADH-quinone oxidoreductase subunit N compare
PP_1860 -1.1 -3.7 Organic hydroperoxide resistance transcriptional regulator compare
PP_5491 -1.1 -1.3 conserved protein of unknown function with SEC-C motif domain compare
PP_2356 -1.1 -5.4 putative Phytochrome family protein compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source 1,3-Hexanediol in Pseudomonas putida KT2440

For carbon source 1,3-Hexanediol across organisms