Experiment set39IT039 for Pseudomonas putida KT2440

Compare to:

MOPS minimal media_Glucose20mM with Lithium chloride 200 mM

200 most detrimental genes:

  gene name fitness t score description  
PP_5145 +3.4 28.7 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0948 +3.4 18.1 Phosphocarrier protein HPr compare
PP_5093 +2.0 1.7 twitching motility protein compare
PP_0340 +1.8 14.0 Glutamate-ammonia-ligase adenylyltransferase compare
PP_5038 +1.4 3.2 conserved lipoprotein of unknown function compare
PP_1237 +1.3 1.5 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_0719 +1.3 2.3 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_4593 +1.2 1.4 conserved protein of unknown function compare
PP_5048 +1.2 4.9 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG compare
PP_4942 +1.2 3.4 conserved protein of unknown function compare
PP_5146 +1.1 3.9 RNA pyrophosphohydrolase compare
PP_1938 +1.1 1.6 conserved protein of unknown function compare
PP_3902 +1.0 2.9 conserved protein of unknown function compare
PP_1650 +1.0 9.5 Sensor protein GacS compare
PP_2378 +1.0 4.0 Fe/S biogenesis protein NfuA compare
PP_2387 +1.0 2.6 conserved protein of unknown function compare
PP_t11 +1.0 2.0 tRNA-Lys compare
PP_0191 +1.0 2.2 Transcriptional regulatory protein AlgQ compare
PP_t49 +1.0 4.0 tRNA-Met compare
PP_1623 +0.9 6.6 RNA polymerase, sigma S (sigma 38) factor compare
PP_0607 +0.9 3.3 putative Type IV pili biogenesis protein FimT compare
PP_2101 +0.9 2.6 DNA-binding response regulator in two-component regulatory system with EvgS compare
PP_3239 +0.9 1.8 putative cointegrate resolution protein T Tn4652 compare
PP_0246 +0.9 3.0 two-component system DNA-binding response transcriptional dual regulator compare
PP_5042 +0.9 3.3 conserved protein of unknown function compare
PP_2510 +0.9 2.1 conserved protein of unknown function compare
PP_2640 +0.8 2.9 Acetyltransferase, GNAT family compare
PP_0232 +0.8 0.9 ATP-binding taurine transporter subunit compare
PP_2474 +0.8 1.6 Glutathione S-transferase family protein compare
PP_1473 +0.8 2.4 conserved protein of unknown function compare
PP_4171 +0.8 6.9 conserved exported protein of unknown function compare
PP_1544 +0.8 2.5 conserved protein of unknown function compare
PP_3245 +0.8 1.2 conserved protein of unknown function compare
PP_0574 +0.8 6.0 DNA-binding response regulator, LuxR family compare
PP_2417 +0.8 2.3 putative Iron ABC transporter, permease protein compare
PP_4099 +0.8 7.6 two-componenent system BarA/UvrY - regulatory subunit compare
PP_3417 +0.8 2.7 D-gluconate transporter compare
PP_4944 +0.8 4.7 Carbamoyltransferase compare
PP_3098 +0.8 1.7 conserved protein of unknown function compare
PP_0805 +0.8 5.5 Outer membrane efflux protein compare
PP_t10 +0.8 1.4 tRNA-Pro compare
PP_0806 +0.7 6.9 putative Surface adhesion protein compare
PP_t12 +0.7 0.6 tRNA-Thr compare
PP_0306 +0.7 2.2 conserved protein of unknown function compare
PP_1020 +0.7 1.8 putative glucose-6-phosphate 1-epimerase compare
PP_4941 +0.7 5.4 conserved exported protein of unknown function compare
PP_3043 +0.7 1.7 conserved protein of unknown function compare
PP_4517 +0.7 1.2 conserved protein of unknown function compare
PP_4238 +0.7 1.7 conserved protein of unknown function compare
PP_5329 +0.7 4.4 putative phosphate ABC transporter, periplasmic phosphate-binding protein compare
PP_5337 +0.7 2.5 LysR family transcriptional regulator compare
PP_2031 +0.7 0.7 conserved protein of unknown function compare
PP_5140 +0.7 1.7 Transcriptional regulator, MerR family compare
PP_1016 +0.7 4.4 mannose/glucose ABC transporter, permease protein compare
PP_1862 +0.7 2.6 conserved membrane protein of unknown function compare
PP_3036 +0.7 2.1 conserved protein of unknown function compare
PP_1018 +0.7 3.6 mannose/glucose ABC transporter - ATP binding subunit compare
PP_2511 +0.7 1.2 conserved protein of unknown function compare
PP_1363 +0.7 2.5 conserved protein of unknown function compare
PP_0429 +0.7 3.7 Oxidoreductase, short chain dehydrogenase/reductase family compare
PP_5552 +0.6 2.5 conserved protein of unknown function compare
PP_5008 +0.6 0.9 Poly granule-associated protein compare
PP_3392 +0.6 0.5 conserved protein of unknown function compare
PP_4254 +0.6 0.7 conserved protein of unknown function compare
PP_1632 +0.6 1.3 conserved protein of unknown function compare
PP_5705 +0.6 1.3 protein of unknown function compare
PP_4874 +0.6 0.7 50S ribosomal protein L9 compare
PP_0628 +0.6 2.9 conserved protein of unknown function compare
PP_1808 +0.6 2.0 glucose-6-phosphate isomerase compare
PP_0509 +0.6 1.4 conserved protein of unknown function compare
PP_5053 +0.6 3.1 Protein-export protein SecB compare
PP_1812 +0.6 1.2 conserved protein of unknown function compare
PP_0003 +0.6 2.1 16S RNA methyltransferase compare
PP_1113 +0.6 4.2 Pyridoxal-phosphate dependent enzyme family protein compare
PP_t29 +0.6 0.7 tRNA-Ala compare
PP_5628 +0.6 1.8 conserved protein of unknown function compare
PP_0610 +0.6 2.3 conserved exported protein of unknown function compare
PP_1012 +0.6 2.2 DNA-binding response regulator compare
PP_5127 +0.6 3.4 ribosomal RNA large subunit methyltransferase I compare
PP_4581 +0.6 1.2 putative amidotransferase compare
PP_1445 +0.6 4.1 carbohydrate-selective porin compare
PP_3837 +0.5 1.7 inner membrane protein of unknown function compare
PP_5017 +0.5 0.8 Sec-independent protein translocase protein TatB compare
PP_0058 +0.5 5.0 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
PP_3825 +0.5 1.7 conserved protein of unknown function compare
PP_1646 +0.5 2.7 putative Thioredoxin compare
PP_4837 +0.5 1.4 conserved protein of unknown function compare
PP_4792 +0.5 2.2 conserved exported protein of unknown function compare
PP_5328 +0.5 3.7 putative phosphate transport system permease protein compare
PP_5441 +0.5 1.1 protein of unknown function compare
PP_2816 +0.5 1.6 putative Transcriptional regulator NfxB compare
PP_0547 +0.5 2.9 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_3519 +0.5 0.5 putative Lipoprotein compare
PP_0128 +0.5 3.5 conserved protein of unknown function compare
PP_1504 +0.5 2.9 conserved protein of unknown function compare
PP_1757 +0.5 1.8 DNA-binding transcriptional dual regulator compare
PP_0666 +0.5 1.5 conserved protein of unknown function compare
PP_1138 +0.5 1.7 branched chain amino acid transporter - ATP binding subunit compare
PP_1067 +0.5 4.0 Sensor histidine kinase compare
PP_2568 +0.5 0.7 Ring-cleaving dioxygenase compare
PP_0137 +0.5 3.4 glutamate/aspartate-proton DAACS transporter compare
PP_2738 +0.5 1.6 putative Transcriptional regulator compare
PP_5609 +0.5 1.1 conserved protein of unknown function compare
PP_5483 +0.5 0.8 conserved protein of unknown function compare
PP_0905 +0.5 0.9 conserved exported protein of unknown function compare
PP_4846 +0.5 2.5 L-amino acid N-acyltransferase compare
PP_4778 +0.5 1.3 23S rRNA pseudouridine 2457 synthase compare
PP_2054 +0.5 1.5 putative DNA-binding transcriptional regulator compare
PP_4332 +0.5 1.6 Chemotaxis protein CheW compare
PP_2060 +0.5 1.3 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_1017 +0.5 2.5 mannose/glucose ABC transporter, permease protein compare
PP_5652 +0.5 1.0 conserved protein of unknown function, phage origin compare
PP_0804 +0.5 2.9 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_0674 +0.5 3.3 ADP/ATP ratio sensor and inhibitor of translation compare
PP_4268 +0.5 0.7 nucleoid-associated broad specificity regulator compare
PP_5007 +0.5 1.2 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_0048 +0.5 0.6 conserved protein of unknown function compare
PP_0181 +0.5 1.5 conserved protein of unknown function compare
PP_4285 +0.5 1.6 5-hydroxyisourate hydrolase compare
PP_0803 +0.5 3.5 Protein secretion ABC efflux system, membrane fusion protein compare
PP_1979 +0.5 1.7 putative Hydrolase compare
PP_2960 +0.5 2.2 transcriptional regulator, AraC family compare
PP_0794 +0.5 1.0 1-phosphofructokinase monomer compare
PP_1385 +0.5 4.3 Probable efflux pump membrane transporter TtgB compare
PP_1071 +0.5 2.9 glutamate / aspartate ABC transporter - periplasmic binding protein compare
PP_4493 +0.5 3.5 D-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
PP_2360 +0.5 2.2 putative type 1 pili subunit CsuA/B protein compare
PP_3643 +0.5 1.8 putative Oxidoreductase compare
PP_3228 +0.5 2.5 putative Periplasmic aliphatic sulfonate-binding protein compare
PP_0504 +0.5 2.2 Outer membrane protein OprG compare
PP_1015 +0.5 2.2 mannose/glucose ABC transporter, glucose-binding periplasmic protein compare
PP_4768 +0.5 2.1 Exonuclease compare
PP_0156 +0.5 2.8 pyridine nucleotide transhydrogenase subunit alpha compare
PP_5359 +0.5 1.0 CobW/P47K family protein compare
PP_4844 +0.5 1.2 putative Urea ABC transporter, ATP-binding protein compare
PP_0151 +0.5 1.1 conserved exported protein of unknown function compare
PP_2866 +0.5 1.8 FMN-dependent NADH-azoreductase 1 compare
PP_3835 +0.5 2.1 Sensory box histidine kinase compare
PP_4835 +0.5 1.1 conserved exported protein of unknown function compare
PP_4184 +0.4 3.0 branched chain amino acid transporter compare
PP_2927 +0.4 2.1 conserved protein of unknown function compare
PP_4601 +0.4 2.2 Transcriptional regulator, LysR family compare
PP_4789 +0.4 1.6 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_0620 +0.4 1.8 GntR family transcriptional regulator compare
PP_2970 +0.4 1.4 conserved exported protein of unknown function compare
PP_4836 +0.4 1.4 conserved exported protein of unknown function compare
PP_1193 +0.4 1.3 conserved membrane protein of unknown function compare
PP_5582 +0.4 0.6 conserved protein of unknown function compare
PP_4132 +0.4 2.0 conserved protein of unknown function compare
PP_1645 +0.4 1.6 putative enzyme compare
PP_2319 +0.4 1.2 conserved protein of unknown function compare
PP_4916 +0.4 1.3 putative esterase compare
PP_4504 +0.4 0.8 conserved exported protein of unknown function compare
PP_2880 +0.4 0.9 Transcriptional regulator, TetR family compare
PP_1548 +0.4 0.8 conserved protein of unknown function compare
PP_2138 +0.4 2.0 conserved protein of unknown function compare
PP_3774 +0.4 1.6 conserved protein of unknown function compare
PP_1692 +0.4 0.8 conserved protein of unknown function compare
PP_3582 +0.4 2.9 RND efflux transporter, outer membrane protein compare
PP_1386 +0.4 2.6 Probable efflux pump periplasmic linker TtgA compare
PP_0827 +0.4 1.2 putative phosphonate transport system permease protein PtxC compare
PP_2958 +0.4 1.1 Glutaredoxin compare
PP_2018 +0.4 1.6 adhesin-associated BNR repeat protein (from data) compare
PP_2745 +0.4 1.7 Universal stress protein family compare
PP_1396 +0.4 1.6 conserved protein of unknown function compare
PP_4930 +0.4 1.2 putative small multidrug resistance protein compare
PP_3280 +0.4 1.0 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase compare
PP_1820 +0.4 2.2 Benzoate transport protein compare
PP_4779 +0.4 3.3 AMP nucleosidase compare
PP_1502 +0.4 1.5 OmpA family protein compare
PP_5327 +0.4 2.7 putative phosphate ABC transporter, permease subunit compare
PP_0826 +0.4 2.0 phosphonate ABC transporter, permease protein compare
PP_1384 +0.4 3.0 Probable efflux pump outer membrane protein TtgC compare
PP_2678 +0.4 2.0 putative Hydrolase compare
PP_2733 +0.4 2.4 conserved membrane protein of unknown function compare
PP_1576 +0.4 1.9 putative Immunity protein compare
PP_4558 +0.4 1.5 Acetyltransferase, GNAT family compare
PP_4793 +0.4 0.8 conserved protein of unknown function compare
PP_0543 +0.4 2.2 ethanolamine ammonia-lyase, alpha-subunit compare
PP_5167 +0.4 1.1 conserved hypothetical protein compare
PP_0782 +0.4 1.2 conserved protein of unknown function compare
PP_0962 +0.4 1.2 toluene-tolerance protein compare
PP_2502 +0.4 2.5 Transcriptional regulator, LysR family compare
PP_3876 +0.4 0.4 conserved protein of unknown function compare
PP_1062 +0.4 0.9 MutT/nudix family protein compare
PP_3320 +0.4 1.2 conserved protein of unknown function compare
PP_4771 +0.4 1.6 conserved membrane protein of unknown function compare
PP_2777 +0.4 1.6 putative Acyl carrier protein compare
PP_5110 +0.4 0.6 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_1589 +0.4 2.6 uridylyltransferase compare
PP_2396 +0.4 1.0 conserved exported protein of unknown function compare
PP_3058 +0.4 1.8 conserved protein of unknown function compare
PP_4629 +0.4 1.3 Sensory box protein compare
PP_1663 +0.4 2.4 conserved exported protein of unknown function compare
PP_4151 +0.4 1.4 Excisionase domain protein compare
PP_1320 +0.4 1.8 stringent starvation protein A compare
PP_0213 +0.4 1.5 succinate-semialdehyde dehydrogenase (NADP+) compare
PP_3597 +0.4 1.8 L-lysine and D-lysine ABC transporter, ATPase component (from data) compare
PP_2939 +0.4 1.3 toxin of the YefM-YoeB antitoxin/toxin complex and DNA-binding transcriptional repressor compare
PP_2345 +0.4 1.0 conserved exported protein of unknown function compare


Specific Phenotypes

For 2 genes in this experiment

For stress Lithium chloride in Pseudomonas putida KT2440

For stress Lithium chloride across organisms