Experiment set38IT032 for Pseudomonas putida KT2440

Compare to:

R2A with Polymyxin B sulfate 0.002 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PP_4355 +2.0 5.0 flagellar export apparatus subunit compare
PP_0959 +1.9 2.7 phospholipid ABC transporter compare
PP_3926 +1.8 2.0 short-chain dehydrogenase compare
PP_0022 +1.5 1.8 hypothetical protein compare
PP_3051 +1.4 2.7 Pyocin R2_PP, tail spike protein compare
PP_0916 +1.3 3.0 Amino acid transporter LysE compare
PP_3328 +1.3 2.5 putative Ring-cleaving dioxygenase compare
PP_1428 +1.3 2.1 Sigma factor AlgU negative regulatory protein compare
PP_0978 +1.2 1.8 conserved protein of unknown function compare
PP_5583 +1.2 1.7 conserved protein of unknown function compare
PP_2681 +1.2 1.8 coenzyme PQQ synthesis protein D compare
PP_3480 +1.2 2.3 conserved protein of unknown function compare
PP_1410 +1.2 1.2 conserved protein of unknown function compare
PP_3447 +1.2 1.4 conserved membrane protein of unknown function compare
PP_5295 +1.2 1.6 conserved protein of unknown function compare
PP_1038 +1.2 2.4 conserved protein of unknown function compare
PP_5423 +1.2 0.9 conserved membrane protein of unknown function compare
PP_3164 +1.1 1.7 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
PP_4396 +1.1 2.5 conserved protein of unknown function compare
PP_2747 +1.1 0.9 conserved protein of unknown function compare
PP_4631 +1.1 3.1 conserved protein of unknown function compare
PP_2510 +1.1 1.8 conserved protein of unknown function compare
PP_2145 +1.1 1.7 beta-N-acetylglucosaminidase compare
PP_2740 +1.1 1.5 Transcriptional regulator, MerR family compare
PP_1825 +1.1 3.9 conserved exported protein of unknown function compare
PP_2655 +1.1 2.2 conserved protein of unknown function compare
PP_0846 +1.1 1.2 DnaK-like molecular chaperone specific for IscU compare
PP_1697 +1.1 1.7 transcriptional regulator, GntR family compare
PP_2029 +1.1 2.2 von Willebrand factor type A domain protein compare
PP_2773 +1.1 1.7 conserved protein of unknown function compare
PP_3357 +1.1 3.2 p-hydroxybenzaldehyde dehydrogenase vdh (EC 1.2.1.64) (from data) compare
PP_1862 +1.1 1.3 conserved membrane protein of unknown function compare
PP_3861 +1.0 2.5 Phage FluMu protein gp46 compare
PP_3808 +1.0 1.6 Antibiotic synthesis protein MbtH compare
PP_1366 +1.0 1.2 Transcriptional regulator MvaT, P16 subunit compare
PP_2509 +1.0 2.1 conserved protein of unknown function compare
PP_0125 +1.0 2.5 putative cytochrome c-type protein compare
PP_2907 +1.0 1.5 DNA-binding response regulator compare
PP_2137 +1.0 1.3 beta-ketoadipyl CoA thiolase, beta component compare
PP_1062 +1.0 2.2 MutT/nudix family protein compare
PP_0425 +1.0 2.5 conserved protein of unknown function compare
PP_5216 +1.0 1.5 exopolyphosphatase compare
PP_2429 +1.0 1.6 putative Membrane protein compare
PP_2055 +1.0 2.1 putative isomerase compare
PP_1892 +1.0 1.2 conserved protein of unknown function compare
PP_4251 +0.9 1.7 cytochrome c oxidase subunit, cbb3-type compare
PP_1142 +0.9 1.0 conserved protein of unknown function compare
PP_4104 +0.9 3.0 Glutathione S-transferase family protein compare
PP_2815 +0.9 2.6 conserved protein of unknown function compare
PP_3136 +0.9 2.0 putative O-acetyltransferase compare
PP_4370 +0.9 1.8 Flagellar hook-basal body complex protein FliE compare
PP_4848 +0.9 1.2 Curved DNA-binding protein compare
PP_3891 +0.9 1.2 conserved protein of unknown function compare
PP_4531 +0.9 2.7 conserved exported protein of unknown function compare
PP_2074 +0.9 2.3 Transcriptional regulator, LysR family compare
PP_3248 +0.9 3.0 Dyp-type peroxidase family protein compare
PP_0574 +0.9 5.5 DNA-binding response regulator, LuxR family compare
PP_4196 +0.9 1.3 conserved exported protein of unknown function compare
PP_1709 +0.9 1.5 Fumarylacetoacetate hydrolase family protein compare
PP_5157 +0.9 3.0 conserved exported protein of unknown function compare
PP_1982 +0.9 2.2 small heat shock protein IbpA compare
PP_4139 +0.9 2.4 conserved protein of unknown function compare
PP_1833 +0.9 2.3 conserved protein of unknown function compare
PP_2661 +0.9 3.0 conserved protein of unknown function compare
PP_1042 +0.9 1.8 Type II secretion system protein K compare
PP_5541 +0.8 1.8 conserved protein of unknown function compare
PP_2280 +0.8 1.6 conserved protein of unknown function compare
PP_3481 +0.8 1.0 conserved exported protein of unknown function compare
PP_0685 +0.8 1.1 conserved protein of unknown function compare
PP_0874 +0.8 1.1 conserved protein of unknown function compare
PP_5093 +0.8 0.9 twitching motility protein compare
PP_3048 +0.8 1.5 conserved protein of unknown function compare
PP_4837 +0.8 1.8 conserved protein of unknown function compare
PP_5619 +0.8 1.1 protein of unknown function compare
PP_5705 +0.8 1.0 protein of unknown function compare
PP_4367 +0.8 2.2 Flagellar assembly protein FliH compare
PP_2342 +0.8 2.5 conserved protein of unknown function compare
PP_1368 +0.8 1.8 putative membrane protein containing a glycosyltransferase domain compare
PP_0735 +0.8 1.4 molybdopterin-synthase adenylyltransferase compare
PP_2373 +0.8 1.2 conserved protein of unknown function compare
PP_2327 +0.8 2.0 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_0377 +0.8 1.1 coenzyme PQQ synthesis protein D compare
PP_3323 +0.8 1.8 CobW/P47K family protein compare
PP_3637 +0.8 0.9 putative Sulfonate ABC transporter, ATP-binding protein compare
PP_0536 +0.8 2.4 conserved protein of unknown function compare
PP_5659 +0.8 1.4 protein of unknown function compare
PP_3412 +0.8 2.7 DNA-binding response regulator, LuxR family compare
PP_4313 +0.8 2.3 putative peptidylprolyl isomerase compare
PP_0805 +0.8 3.8 Outer membrane efflux protein compare
PP_0775 +0.8 0.8 conserved protein of unknown function compare
PP_0961 +0.8 2.8 toluene tolerance protein compare
PP_4162 +0.8 1.7 conserved membrane protein of unknown function compare
PP_2550 +0.8 0.8 putative transcriptional regulatory protein compare
PP_2345 +0.8 1.9 conserved exported protein of unknown function compare
PP_1550 +0.8 2.0 Transcriptional regulator, Cro/CI family compare
PP_2990 +0.8 2.0 Transcriptional regulator, MerR family compare
PP_3539 +0.8 1.3 putative Transcriptional regulator compare
PP_3484 +0.8 2.2 Response regulator receiver protein compare
PP_4911 +0.8 2.7 conserved protein of unknown function compare
PP_2078 +0.8 1.2 transcriptional activator protein LysR compare
PP_2745 +0.8 1.4 Universal stress protein family compare
PP_3824 +0.8 2.2 conserved exported protein of unknown function compare
PP_2615 +0.8 1.8 hemolysin-coregulated protein compare
PP_4385 +0.8 3.5 flagellar basal-body rod protein FlgG compare
PP_5520 +0.8 1.5 conserved protein of unknown function compare
PP_2358 +0.8 2.8 putative Type 1 pili subunit CsuA/B protein compare
PP_2171 +0.8 1.3 Transporter, LysE family compare
PP_3798 +0.8 1.7 conserved protein of unknown function compare
PP_4534 +0.8 1.9 conserved protein of unknown function compare
PP_2814 +0.7 1.8 conserved protein of unknown function compare
PP_3198 +0.7 1.5 Ferredoxin, 2Fe-2S compare
PP_3235 +0.7 2.2 conserved protein of unknown function compare
PP_2898 +0.7 1.1 conserved exported protein of unknown function compare
PP_4368 +0.7 1.8 flagellar motor switch protein compare
PP_5495 +0.7 0.9 protein of unknown function compare
PP_1477 +0.7 1.9 ssDNA-specific exonuclease RecJ compare
PP_5023 +0.7 2.3 Amino acid ABC transporter, permease protein compare
PP_2169 +0.7 1.9 tRNA-dihydrouridine synthase A compare
PP_2900 +0.7 1.1 conserved protein of unknown function compare
PP_2532 +0.7 2.7 conserved protein of unknown function compare
PP_1864 +0.7 1.9 conserved protein of unknown function compare
PP_4904 +0.7 3.5 Flagellar motor rotation protein compare
PP_2717 +0.7 1.8 arsenite/antimonite transporter compare
PP_5SB +0.7 2.1 5S ribosomal RNA compare
PP_0276 +0.7 0.8 Transcriptional regulator, Cro/CI family compare
PP_4231 +0.7 1.9 putative Xanthine dehydrogenase accessory factor compare
PP_1999 +0.7 1.3 membrane protein required for colicin V production compare
PP_4314 +0.7 1.5 conserved protein of unknown function compare
PP_0848 +0.7 1.1 donor of Fe2+ and regulator of cysteine desulfurase activity compare
PP_3893 +0.7 2.6 putative Phage DNA helicase compare
PP_0850 +0.7 2.1 Dual-specificity RNA methyltransferase RlmN compare
PP_2530 +0.7 1.0 conserved protein of unknown function compare
PP_4681 +0.7 0.8 conserved protein of unknown function compare
PP_0784 +0.7 2.3 conserved protein of unknown function compare
PP_t64 +0.7 1.7 tRNA-Gly compare
PP_5499 +0.7 1.2 conserved protein of unknown function compare
PP_5597 +0.7 1.6 conserved protein of unknown function compare
PP_4905 +0.7 2.3 Flagellar motor rotation protein compare
PP_2527 +0.7 1.9 conserved membrane protein of unknown function compare
PP_1527 +0.7 2.1 tRNA threonylcarbamoyladenosine dehydratase (t(6)A37 dehydratase) compare
PP_2441 +0.7 0.6 conserved protein of unknown function compare
PP_2678 +0.7 1.3 putative Hydrolase compare
PP_2941 +0.7 1.9 conserved protein of unknown function compare
PP_4056 +0.7 2.3 putative phosphohydrolase of unknown function compare
PP_5553 +0.7 2.6 conserved protein of unknown function compare
PP_3968 +0.7 3.0 Sensor histidine kinase compare
PP_0634 +0.7 2.1 Fimbrial protein compare
PP_3930 +0.7 1.4 conserved exported protein of unknown function compare
PP_2624 +0.7 2.5 conserved protein of unknown function compare
PP_5696 +0.7 1.8 conserved protein of unknown function compare
PP_1556 +0.7 1.0 conserved protein of unknown function compare
PP_1542 +0.7 2.6 conserved protein of unknown function compare
PP_2983 +0.7 2.5 conserved protein of unknown function compare
PP_4394 +0.7 2.1 flagella basal body P-ring formation protein compare
PP_5267 +0.7 0.9 putative cytochrome c5 compare
PP_0804 +0.7 3.2 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_2668 +0.7 0.7 ABC efflux transporter, ATP-binding protein compare
PP_5621 +0.7 0.9 protein of unknown function compare
PP_4373 +0.7 4.5 Transcriptional regulator FleQ compare
PP_4380 +0.7 4.0 Flagellar hook-associated protein FlgL compare
PP_3013 +0.7 1.2 conserved protein of unknown function compare
PP_4789 +0.7 1.9 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_2401 +0.7 2.4 conserved membrane protein of unknown function compare
PP_0273 +0.7 1.9 conserved protein of unknown function compare
PP_3121 +0.7 1.7 transcriptional regulator, LysR family compare
PP_1763 +0.7 1.3 putative oxidoreductase compare
PP_4384 +0.7 3.5 Flagellar L-ring protein compare
PP_4073 +0.7 0.6 conserved exported protein of unknown function compare
PP_2754 +0.7 2.6 putative OprD family outer membrane porin compare
PP_3288 +0.7 2.2 Universal stress protein family compare
PP_0837 +0.7 2.7 putative regulator of flagellation compare
PP_2014 +0.7 1.8 conserved membrane protein of unknown function compare
PP_4923 +0.7 3.5 Outer membrane efflux protein compare
PP_5664 +0.6 1.5 conserved protein of unknown function compare
PP_3438 +0.6 1.7 conserved membrane protein of unknown function compare
PP_3983 +0.6 3.6 conserved protein of unknown function compare
PP_0206 +0.6 2.4 Ferredoxin, 4Fe-4S compare
PP_1626 +0.6 2.6 DNA mismatch repair protein MutS compare
PP_3145 +0.6 2.2 conserved protein of unknown function compare
PP_2726 +0.6 2.4 conserved membrane protein of unknown function compare
PP_0989 +0.6 1.7 glycine cleavage system H protein 1 compare
PP_1352 +0.6 1.2 UPF0234 protein PP_1352 compare
PP_0806 +0.6 5.4 putative Surface adhesion protein compare
PP_0086 +0.6 1.2 conserved protein of unknown function compare
PP_1518 +0.6 1.8 conserved exported protein of unknown function compare
PP_2254 +0.6 1.2 Transcriptional regulator, GntR family compare
PP_0126 +0.6 0.9 Cytochrome c4 compare
PP_2568 +0.6 0.7 Ring-cleaving dioxygenase compare
PP_2836 +0.6 2.3 putative 2-keto-3-deoxyxylonate dehydratase compare
PP_3301 +0.6 2.5 RND efflux membrane fusion protein compare
PP_4386 +0.6 1.9 flagellar basal-body rod protein FlgF compare
PP_5530 +0.6 2.1 protein of unknown function compare
PP_4645 +0.6 1.5 Large-conductance mechanosensitive channel compare
PP_3699 +0.6 3.5 conserved protein of unknown function compare
PP_2016 +0.6 1.1 conserved protein of unknown function compare
PP_5155 +0.6 1.4 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_3290 +0.6 2.1 Universal stress protein family compare
PP_4734 +0.6 2.4 DNA-binding transcriptional dual regulator, LldR-L-lactate compare
PP_3672 +0.6 1.6 conserved protein of unknown function compare
PP_1429 +0.6 2.1 Sigma factor AlgU regulatory protein MucB compare


Specific Phenotypes

None in this experiment

For Pseudomonas putida KT2440 in stress experiments

For stress Polymyxin B sulfate across organisms