Experiment set38IT026 for Pseudomonas putida KT2440

Compare to:

R2A with Polymyxin B sulfate 0.001 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PP_0903 +4.9 11.9 conserved protein of unknown function compare
PP_4058 +4.3 27.5 1,4-alpha-glucan branching enzyme compare
PP_0025 +3.0 7.2 hypothetical protein compare
PP_0904 +2.1 9.2 InaA protein compare
PP_2136 +1.9 6.7 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_2862 +1.9 10.9 Undecaprenyl-diphosphatase compare
PP_3840 +1.8 5.0 conserved protein of unknown function compare
PP_2403 +1.8 1.1 Chemotaxis protein CheY compare
PP_1293 +1.8 2.4 molybdopterin synthase small subunit compare
PP_5453 +1.7 3.4 conserved protein of unknown function compare
PP_2137 +1.6 4.1 beta-ketoadipyl CoA thiolase, beta component compare
PP_3198 +1.5 1.1 Ferredoxin, 2Fe-2S compare
PP_3102 +1.4 3.8 conserved protein of unknown function compare
PP_2773 +1.4 2.4 conserved protein of unknown function compare
PP_0346 +1.3 6.2 putative Heptose kinase WapQ compare
PP_0087 +1.3 3.5 conserved exported protein of unknown function compare
PP_4811 +1.3 2.1 Gamma-glutamyl phosphate reductase compare
PP_1568 +1.3 2.8 conserved protein of unknown function compare
PP_2433 +1.2 3.6 conserved protein of unknown function compare
PP_1862 +1.2 1.5 conserved membrane protein of unknown function compare
PP_5054 +1.2 2.7 glutaredoxin 3 compare
PP_5471 +1.2 2.7 putative response regulator receiver protein compare
PP_4120 +1.2 2.4 NADH-quinone oxidoreductase subunit B compare
PP_1575 +1.1 1.6 conserved protein of unknown function compare
PP_1054 +1.1 1.3 Type II secretion pathway protein XcpZ compare
PP_0801 +1.1 2.5 conserved exported protein of unknown function compare
PP_0905 +1.1 2.3 conserved exported protein of unknown function compare
PP_t64 +1.1 1.7 tRNA-Gly compare
PP_0153 +1.0 2.9 hypothetical protein compare
PP_1109 +1.0 5.7 Transcriptional regulator, GntR family compare
PP_1381 +1.0 1.8 4-carboxymuconolactone decarboxylase compare
PP_0035 +1.0 2.2 putative bactoprenol-linked glycose transferase compare
PP_2756 +1.0 1.2 conserved protein of unknown function compare
PP_2693 +1.0 1.6 putative Dipeptidase compare
PP_4268 +1.0 1.9 nucleoid-associated broad specificity regulator compare
PP_4122 +1.0 1.7 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_0900 +1.0 2.3 PAP2 family protein compare
PP_1729 +1.0 0.8 conserved protein of unknown function compare
PP_3000 +0.9 3.2 MaoC domain protein compare
PP_2715 +0.9 2.1 ArsH protein compare
PP_2396 +0.9 1.8 conserved exported protein of unknown function compare
PP_1655 +0.9 1.7 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_4837 +0.9 3.2 conserved protein of unknown function compare
PP_2969 +0.9 4.1 putative repressor of copper utilisation proteins compare
PP_4988 +0.9 4.4 signal transduction histidine kinase CheA/CheY-like receiver compare
PP_3239 +0.9 1.6 putative cointegrate resolution protein T Tn4652 compare
PP_4549 +0.9 5.7 long-chain-fatty-acid/CoA ligase compare
PP_1142 +0.8 1.3 conserved protein of unknown function compare
PP_1926 +0.8 1.4 putative phosphotyrosine-protein phosphatase compare
PP_4213 +0.8 1.3 putative dipeptidase compare
PP_1111 +0.8 2.9 putative Synthetase compare
PP_2678 +0.8 2.5 putative Hydrolase compare
PP_4355 +0.8 2.2 flagellar export apparatus subunit compare
PP_3447 +0.8 1.3 conserved membrane protein of unknown function compare
PP_1770 +0.8 2.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
PP_3205 +0.8 2.5 Fumarylacetoacetate hydrolase family protein compare
PP_0959 +0.8 1.7 phospholipid ABC transporter compare
PP_2197 +0.8 2.3 conserved exported protein of unknown function compare
PP_1122 +0.8 2.2 OmpA family protein compare
PP_0628 +0.8 3.1 conserved protein of unknown function compare
PP_4143 +0.7 1.8 conserved protein of unknown function compare
PP_2018 +0.7 2.0 adhesin-associated BNR repeat protein (from data) compare
PP_2504 +0.7 1.0 putative tautomerase K2 compare
PP_3726 +0.7 0.7 Enoyl-CoA hydratase/isomerase family protein compare
PP_5177 +0.7 3.8 spermidine/putrescine ABC transporter - permease subunit compare
PP_0574 +0.7 5.5 DNA-binding response regulator, LuxR family compare
PP_3902 +0.7 1.8 conserved protein of unknown function compare
PP_0827 +0.7 1.4 putative phosphonate transport system permease protein PtxC compare
PP_1855 +0.7 0.8 conserved exported protein of unknown function compare
PP_4993 +0.7 3.0 Glutathione synthetase compare
PP_4944 +0.7 1.2 Carbamoyltransferase compare
PP_4066 +0.7 1.4 methylglutaconyl-CoA hydratase compare
PP_5505 +0.7 1.7 conserved transmembrane protein of unknown function compare
PP_1110 +0.7 1.4 serine acetyltransferase compare
PP_3336 +0.7 1.9 conserved protein of unknown function compare
PP_5267 +0.7 1.4 putative cytochrome c5 compare
PP_0865 +0.7 1.9 ECF subfamily RNA polymerase sigma-24 factor compare
PP_3748 +0.7 1.4 conserved hypothetical protein compare
PP_1826 +0.7 1.4 Hydrolase, isochorismatase family compare
PP_2060 +0.7 1.1 DNA-binding transcriptional dual regulator - SoxR-reversible one-electron oxidation of its [2Fe-2S] cluster, NADPH-dependent compare
PP_3919 +0.7 2.5 conserved protein of unknown function compare
PP_2806 +0.7 1.2 Transcriptional regulator, TetR family compare
PP_4513 +0.7 2.1 conserved protein of unknown function compare
PP_4469 +0.7 2.7 ribose 1,5-bisphosphate phosphokinase compare
PP_5495 +0.7 1.1 protein of unknown function compare
PP_2737 +0.7 1.2 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_3767 +0.7 2.6 conserved protein of unknown function compare
PP_5519 +0.7 1.0 conserved protein of unknown function of phage origin compare
PP_3647 +0.6 1.7 putative Oxidoreductase compare
PP_0630 +0.6 0.9 DNA gyrase inhibitor YacG compare
PP_2610 +0.6 1.9 conserved protein of unknown function compare
PP_2379 +0.6 2.0 putative cytochrome oxidase biogenesis protein compare
PP_5276 +0.6 3.8 Phospholipase D family protein compare
PP_2506 +0.6 2.4 conserved membrane protein of unknown function compare
PP_5712 +0.6 1.6 conserved protein of unknown function compare
PP_3481 +0.6 0.9 conserved exported protein of unknown function compare
PP_2110 +0.6 1.5 putative ribosomal large subunit pseudouridine synthase compare
PP_1836 +0.6 1.3 putative metal transporter, ZIP family compare
PP_5473 +0.6 1.7 putative transcriptional regulator, LuxR family compare
PP_5689 +0.6 2.4 conserved protein of unknown function compare
PP_0422 +0.6 1.6 Indole-3-glycerol phosphate synthase compare
PP_4109 +0.6 1.8 conserved protein of unknown function compare
PP_1439 +0.6 0.9 conserved exported protein of unknown function compare
PP_3591 +0.6 1.7 Delta 1-piperideine-2-carboxylate reductase compare
PP_5595 +0.6 1.8 conserved exported protein of unknown function compare
PP_4551 +0.6 2.8 Hydrolase, alpha/beta fold family compare
PP_3041 +0.6 2.0 conserved protein of unknown function compare
PP_5621 +0.6 1.3 protein of unknown function compare
PP_5678 +0.6 1.7 protein of unknown function compare
PP_1731 +0.6 1.7 23S rRNA (746) and tRNA (32) pseudouridine synthase compare
PP_2899 +0.6 1.1 conserved exported protein of unknown function compare
PP_2640 +0.6 0.9 Acetyltransferase, GNAT family compare
PP_5534 +0.6 1.8 protein of unknown function compare
PP_0332 +0.6 2.6 putative Acyltransferase compare
PP_1774 +0.6 1.8 conserved exported protein of unknown function compare
PP_5232 +0.6 1.6 conserved protein of unknown function compare
PP_4444 +0.6 1.3 transposase compare
PP_4797 +0.6 1.0 conserved protein of unknown function compare
PP_4223 +0.6 1.0 diaminobutyrate-2-oxoglutarate transaminase compare
PP_0804 +0.6 3.2 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_1364 +0.6 3.2 conserved exported protein of unknown function compare
PP_3571 +0.6 2.2 putative Acetylornithine deacetylase compare
PP_4787 +0.6 1.7 putative protein with nucleoside triphosphate hydrolase domain compare
PP_3693 +0.6 1.2 putative Transcriptional regulator MvaT, P16 subunit compare
PP_2735 +0.6 2.3 conserved protein of unknown function compare
PP_3035 +0.6 1.4 conserved protein of unknown function compare
PP_5055 +0.5 2.0 Sulfurtransferase compare
PP_4531 +0.5 2.4 conserved exported protein of unknown function compare
PP_2536 +0.5 1.6 Glutathione S-transferase family protein compare
PP_4362 +0.5 0.9 conserved protein of unknown function compare
PP_3729 +0.5 1.8 Periplasmic amino acid-binding protein-related protein compare
PP_0058 +0.5 3.4 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
PP_2525 +0.5 1.1 conserved protein of unknown function compare
PP_5047 +0.5 2.2 two-component system sensory histidine kinase/phosphatase GlnL/GlnG compare
PP_0806 +0.5 4.9 putative Surface adhesion protein compare
PP_0547 +0.5 1.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_3359 +0.5 2.1 putative Hydroxycinnamic acid degradation regulator compare
PP_1788 +0.5 0.8 conserved protein of unknown function compare
PP_4470 +0.5 1.5 putative transcriptional regulator (Arc domain-containing) compare
PP_3301 +0.5 2.2 RND efflux membrane fusion protein compare
PP_0941 +0.5 1.1 putative ribosome associated protein compare
PP_2650 +0.5 0.9 putative 4-hydroxybutyrate dehydrogenase compare
PP_5338 +0.5 1.7 aspartate ammonia-lyase compare
PP_3883 +0.5 1.4 putative Phage holin compare
PP_5174 +0.5 1.7 Efflux membrane fusion protein, RND family compare
PP_1738 +0.5 3.0 conserved exported protein of unknown function compare
PP_0803 +0.5 2.4 Protein secretion ABC efflux system, membrane fusion protein compare
PP_2148 +0.5 3.2 transcription-repair coupling factor compare
PP_4989 +0.5 1.7 Protein PilJ compare
PP_4196 +0.5 1.0 conserved exported protein of unknown function compare
PP_4642 +0.5 0.7 Cyclic diguanosine monophosphate-binding protein compare
PP_5179 +0.5 2.3 spermidine/putrescine ABC transporter - ATP binding subunit compare
PP_3231 +0.5 1.3 conserved protein of unknown function compare
PP_0621 +0.5 1.6 conserved protein of unknown function compare
PP_5529 +0.5 1.0 putative epimerase compare
PP_4365 +0.5 2.4 Flagellar protein FliJ compare
PP_1667 +0.5 2.5 putative Transporter compare
PP_0805 +0.5 2.9 Outer membrane efflux protein compare
PP_0191 +0.5 2.1 Transcriptional regulatory protein AlgQ compare
PP_4820 +0.5 1.8 tRNA-dihydrouridine synthase B compare
PP_1482 +0.5 1.3 polyamine ABC transporter, permease protein compare
PP_3864 +0.5 1.6 putative Phage FluMu DNA circulation protein compare
PP_2768 +0.5 1.7 putative Branched-chain amino acid ABC transporter, permease protein compare
PP_5504 +0.5 0.8 conserved protein of unknown function compare
PP_1907 +0.5 1.8 Hydrolase, haloacid dehalogenase-like family compare
PP_2078 +0.5 1.7 transcriptional activator protein LysR compare
PP_4520 +0.5 1.9 conserved protein of unknown function compare
PP_5295 +0.5 1.3 conserved protein of unknown function compare
PP_3735 +0.5 2.0 ABC transporter ATP-binding protein compare
PP_5092 +0.5 2.4 putative exported NLP/P60 protein compare
PP_1892 +0.5 1.4 conserved protein of unknown function compare
PP_5711 +0.5 1.5 protein of unknown function compare
PP_0989 +0.5 1.2 glycine cleavage system H protein 1 compare
PP_4620 +0.5 2.7 Fumarylacetoacetase compare
PP_1406 +0.5 2.6 conserved protein of unknown function compare
PP_3833 +0.5 1.5 Response regulator compare
PP_1605 +0.5 1.4 Ribonuclease HII compare
PP_2425 +0.5 1.7 putative transcriptional regulator, AraC family compare
PP_5552 +0.5 0.7 conserved protein of unknown function compare
PP_3034 +0.5 0.9 putative Regulator protein compare
PP_5159 +0.5 2.0 conserved protein of unknown function compare
PP_5562 +0.5 1.5 conserved protein of unknown function compare
PP_0152 +0.5 1.4 conserved exported protein of unknown function compare
PP_0286 +0.5 1.8 adenine glycosylase compare
PP_2313 +0.5 0.9 conserved membrane protein of unknown function compare
PP_1737 +0.5 3.2 conserved protein of unknown function compare
PP_2345 +0.5 1.6 conserved exported protein of unknown function compare
PP_0398 +0.5 1.2 Thiosulfate sulfurtransferase GlpE compare
PP_0821 +0.5 1.1 conserved exported protein of unknown function compare
PP_1367 +0.5 1.9 formyltetrahydrofolate hydrolase compare
PP_1736 +0.5 1.5 conserved protein of unknown function compare
PP_2101 +0.5 1.4 DNA-binding response regulator in two-component regulatory system with EvgS compare
PP_3019 +0.5 1.5 Carbon-nitrogen hydrolase family protein compare
PP_2203 +0.5 1.2 conserved protein of unknown function compare
PP_3524 +0.4 1.1 conserved protein of unknown function compare
PP_0283 +0.4 1.2 Arginine/ornithine transport ATP-binding protein AotP compare
PP_3419 +0.4 2.1 Sigma-54 dependent transcriptional regulator/response regulator compare
PP_2779 +0.4 1.4 putative Beta-ketoacyl synthase compare
PP_1806 +0.4 1.4 putative arabinose 5-phosphate isomerase compare
PP_3904 +0.4 1.2 conserved protein of unknown function compare


Specific Phenotypes

For 2 genes in this experiment

For stress Polymyxin B sulfate in Pseudomonas putida KT2440

For stress Polymyxin B sulfate across organisms