Experiment set38IT005 for Escherichia coli BW25113

Compare to:

LB

200 most important genes:

  gene name fitness t score description  
b2285 nuoE -3.6 -4.2 NADH dehydrogenase subunit E (NCBI) compare
b1290 sapF -2.5 -2.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0737 tolQ -2.4 -4.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2567 rnc -2.3 -1.6 ribonuclease III (NCBI) compare
b0232 yafN -1.9 -1.3 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0740 tolB -1.9 -5.4 translocation protein TolB precursor (NCBI) compare
b3613 yibP -1.9 -4.9 putative membrane protein (VIMSS) compare
b0738 tolR -1.8 -3.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2935 tktA -1.8 -2.4 transketolase 1, thiamin-binding (NCBI) compare
b3183 obgE -1.7 -2.2 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1192 ldcA -1.7 -5.7 L,D-carboxypeptidase A (NCBI) compare
b2276 nuoN -1.7 -6.2 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b2280 nuoJ -1.6 -5.9 NADH dehydrogenase subunit J (NCBI) compare
b2168 fruK -1.6 -2.0 1-phosphofructokinase (NCBI) compare
b1860 ruvB -1.6 -1.4 Holliday junction DNA helicase B (NCBI) compare
b2279 nuoK -1.6 -1.7 NADH dehydrogenase subunit K (NCBI) compare
b3021 ygiT -1.6 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b3290 trkA -1.6 -1.5 potassium transporter peripheral membrane component (NCBI) compare
b4647 mokA -1.5 -1.0 no description compare
b2278 nuoL -1.5 -8.3 NADH dehydrogenase subunit L (NCBI) compare
b2283 nuoG -1.5 -6.5 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b4155 yjeA -1.4 -1.0 putative lysyl-tRNA synthetase (VIMSS) compare
b0741 pal -1.4 -3.5 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2284 nuoF -1.4 -4.9 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b3979 thrT -1.4 -0.7 tRNA-Thr (NCBI) compare
b2287 nuoB -1.4 -3.8 NADH dehydrogenase subunit B (NCBI) compare
b2286 nuoC -1.3 -4.6 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b4655 ythA -1.3 -1.7 expressed protein (RefSeq) compare
b0722 sdhD -1.3 -5.0 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b0726 sucA -1.3 -3.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b4603 rseX -1.3 -1.1 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b0683 fur -1.2 -1.7 ferric uptake regulator (NCBI) compare
b0149 mrcB -1.2 -10.0 penicillin-binding protein 1b (NCBI) compare
b2277 nuoM -1.2 -5.3 NADH dehydrogenase subunit M (NCBI) compare
b1709 btuD -1.2 -1.3 vitamin B12-transporter ATPase (NCBI) compare
b1062 pyrC -1.2 -6.2 dihydroorotase (NCBI) compare
b2830 nudH -1.1 -1.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b4202 rpsR -1.1 -1.8 30S ribosomal protein S18 (NCBI) compare
b2281 nuoI -1.1 -2.9 NADH dehydrogenase subunit I (NCBI) compare
b2282 nuoH -1.1 -3.0 NADH dehydrogenase subunit H (NCBI) compare
b3916 pfkA -1.1 -2.4 6-phosphofructokinase (NCBI) compare
b4375 prfC -1.1 -3.4 peptide chain release factor 3 (NCBI) compare
b0724 sdhB -1.1 -4.6 succinate dehydrogenase, FeS subunit (NCBI) compare
b2330 yfcB -1.1 -1.5 putative adenine-specific methylase (VIMSS) compare
b1058 yceO -1.1 -0.7 hypothetical protein (NCBI) compare
b0630 lipB -1.0 -1.1 protein of lipoate biosynthesis (VIMSS) compare
b3806 cyaA -1.0 -4.1 adenylate cyclase (NCBI) compare
b2820 recB -1.0 -0.9 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2576 srmB -1.0 -2.7 ATP-dependent RNA helicase (NCBI) compare
b0200 gmhB -1.0 -1.3 hypothetical protein (NCBI) compare
b0658 ybeX -0.9 -1.2 predicteed ion transport (NCBI) compare
b0890 ftsK -0.9 -3.4 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1160 elbA -0.9 -0.6 hypothetical protein (NCBI) compare
b1281 pyrF -0.9 -3.0 orotidine 5'-phosphate decarboxylase (NCBI) compare
b4701 sokX -0.9 -0.8 sok-related sRNA, function unknown (RefSeq) compare
b2897 ygfY -0.9 -3.2 hypothetical protein (NCBI) compare
b3169 nusA -0.9 -2.7 transcription elongation factor NusA (NCBI) compare
b4042 dgkA -0.9 -1.7 diacylglycerol kinase (NCBI) compare
b2699 recA -0.8 -1.1 recombinase A (NCBI) compare
b4139 aspA -0.8 -6.0 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b0928 aspC -0.8 -5.1 aspartate aminotransferase, PLP-dependent (NCBI) compare
b0080 fruR -0.8 -3.4 DNA-binding transcriptional dual regulator (NCBI) compare
b3842 rfaH -0.8 -4.0 transcriptional activator RfaH (NCBI) compare
b0386 proC -0.8 -3.7 pyrroline-5-carboxylate reductase (NCBI) compare
b4515 ybgT -0.8 -1.8 hypothetical protein (NCBI) compare
b0945 pyrD -0.8 -4.9 dihydroorotate dehydrogenase (NCBI) compare
b4146 yjeK -0.8 -1.6 predicted lysine aminomutase (NCBI) compare
b1084 rne -0.8 -3.9 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b1351 racC -0.8 -0.5 Rac prophage; predicted protein (NCBI) compare
b0720 gltA -0.8 -4.5 citrate synthase (NCBI) compare
b1692 ydiB -0.8 -2.4 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b1951 rcsA -0.8 -1.2 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b3977 tyrU -0.8 -0.8 tRNA-Tyr (NCBI) compare
b0222 lpcA -0.7 -1.8 phosphoheptose isomerase (NCBI) compare
b0723 sdhA -0.7 -5.1 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b1648 b1648 -0.7 -1.6 orf, hypothetical protein (VIMSS) compare
b0523 purE -0.7 -2.3 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b1853 yebK -0.7 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b4695 ykgT -0.7 -1.4 no description compare
b0364 yaiS -0.7 -2.2 orf, hypothetical protein (VIMSS) compare
b1179 ycgL -0.7 -2.1 conserved protein (NCBI) compare
b3636 rpmG -0.7 -1.5 50S ribosomal protein L33 (NCBI) compare
b0721 sdhC -0.7 -3.6 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b0739 tolA -0.7 -1.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0450 glnK -0.7 -2.0 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b1855 lpxM -0.7 -3.7 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b4179 vacB -0.7 -3.5 putative enzyme (VIMSS) compare
b3962 udhA -0.7 -3.5 putative oxidoreductase (VIMSS) compare
b3164 pnp -0.7 -1.4 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1693 aroD -0.7 -3.5 3-dehydroquinate dehydratase (NCBI) compare
b1109 ndh -0.7 -3.0 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b3236 mdh -0.7 -4.0 malate dehydrogenase (NCBI) compare
b0548 ninE -0.7 -2.7 DLP12 prophage; conserved protein (NCBI) compare
b1409 ynbB -0.7 -0.4 predicted CDP-diglyceride synthase (NCBI) compare
b4178 yjeB -0.7 -3.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2110 yehC -0.7 -0.7 predicted periplasmic pilin chaperone (NCBI) compare
b0430 cyoC -0.7 -2.5 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b0728 sucC -0.7 -3.2 succinyl-CoA synthetase subunit beta (NCBI) compare
b1920 fliY -0.6 -1.6 cystine transporter subunit (NCBI) compare
b1691 ydiN -0.6 -2.1 predicted transporter (RefSeq) compare
b0676 nagC -0.6 -3.9 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b3778 rep -0.6 -3.5 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3940 metL -0.6 -4.3 bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) compare
b1429 tehA -0.6 -0.9 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b2288 nuoA -0.6 -1.4 NADH dehydrogenase I chain A (VIMSS) compare
b3860 dsbA -0.6 -4.2 periplasmic protein disulfide isomerase I (NCBI) compare
b3631 rfaG -0.6 -5.2 glucosyltransferase I (NCBI) compare
b1984 asnW -0.6 -1.0 tRNA-Asn (NCBI) compare
b1863 ruvC -0.6 -1.3 Holliday junction resolvase (NCBI) compare
b1235 rssB -0.6 -3.4 response regulator of RpoS (NCBI) compare
b3162 deaD -0.6 -2.5 inducible ATP-independent RNA helicase (VIMSS) compare
b2673 nrdH -0.6 -2.4 glutaredoxin-like protein (NCBI) compare
b0729 sucD -0.6 -1.7 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3500 gor -0.6 -0.9 glutathione reductase (NCBI) compare
b1438 ydcQ -0.6 -1.8 predicted DNA-binding transcriptional regulator (RefSeq) compare
b1361 ydaW -0.6 -0.5 orf, hypothetical protein (VIMSS) compare
b1877 yecT -0.6 -1.3 orf, hypothetical protein (VIMSS) compare
b2906 visC -0.6 -3.4 hypothetical protein (NCBI) compare
b2504 yfgG -0.6 -1.0 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b0564 appY -0.6 -0.6 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b0439 lon -0.6 -2.7 DNA-binding ATP-dependent protease La (NCBI) compare
b3163 nlpI -0.6 -2.9 hypothetical protein (NCBI) compare
b2414 cysK -0.6 -4.1 cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) compare
b3204 ptsN -0.6 -2.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b0550 rusA -0.6 -1.6 DLP12 prophage; endonuclease RUS (NCBI) compare
b3741 gidA -0.6 -2.2 glucose-inhibited division protein A (NCBI) compare
b1185 dsbB -0.6 -1.9 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b0730 mngR -0.6 -0.9 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2259 pmrD -0.5 -0.9 polymyxin resistance protein B (VIMSS) compare
b3935 priA -0.5 -0.9 primosome assembly protein PriA (NCBI) compare
b4370 leuQ -0.5 -1.7 tRNA-Leu (NCBI) compare
b4239 treC -0.5 -0.5 trehalose-6-P hydrolase (NCBI) compare
b1551 b1551 -0.5 -0.3 orf, hypothetical protein (VIMSS) compare
b1291 sapD -0.5 -0.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0088 murD -0.5 -1.3 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b3617 kbl -0.5 -3.3 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b1363 trkG -0.5 -0.3 Rac prophage; potassium transporter subunit (NCBI) compare
b1992 cobS -0.5 -1.6 cobalamin synthase (NCBI) compare
b1533 ydeD -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b1502 ydeQ -0.5 -1.1 predicted fimbrial-like adhesin protein (NCBI) compare
b0957 ompA -0.5 -2.1 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1257 yciE -0.5 -0.3 hypothetical protein (NCBI) compare
b1753 ynjA -0.5 -1.7 hypothetical protein (NCBI) compare
b0161 degP -0.5 -3.4 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b0888 trxB -0.5 -1.8 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b2652 ileY -0.5 -0.3 tRNA-Ile (NCBI) compare
b0033 carB -0.5 -4.0 carbamoyl-phosphate synthase large subunit (NCBI) compare
b0431 cyoB -0.5 -3.8 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b1842 holE -0.5 -1.2 DNA polymerase III, theta subunit (NCBI) compare
b3791 rffA -0.5 -2.7 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b3849 trkH -0.5 -3.7 potassium transporter (NCBI) compare
b3620 rfaF -0.5 -2.4 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2297 pta -0.5 -0.4 phosphate acetyltransferase (NCBI) compare
b3630 rfaP -0.5 -3.4 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b4181 yjfI -0.5 -1.5 hypothetical protein (NCBI) compare
b2937 speB -0.5 -2.9 agmatinase (NCBI) compare
b2814 metZ -0.5 -1.0 tRNA-Met (NCBI) compare
b4481 rffT -0.5 -3.0 4-alpha-L-fucosyltransferase (NCBI) compare
b0627 tatE -0.5 -1.1 twin arginine translocase protein E (NCBI) compare
b3101 yqjF -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b1760 ynjH -0.5 -1.8 hypothetical protein (NCBI) compare
b1689 b1689 -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b3642 pyrE -0.5 -1.5 orotate phosphoribosyltransferase (NCBI) compare
b1613 manA -0.5 -1.0 mannose-6-phosphate isomerase (VIMSS) compare
b4590 ybfK -0.5 -0.4 hypothetical protein (RefSeq) compare
b0934 ycbM -0.5 -1.6 putative transport system permease protein (VIMSS) compare
b1368 ynaA -0.5 -1.3 Rac prophage; predicted tail protein (RefSeq) compare
b2717 hycI -0.5 -3.0 protease involved in processing C-terminal end of HycE (NCBI) compare
b2499 purM -0.5 -2.2 phosphoribosylaminoimidazole synthetase (NCBI) compare
b0798 ybiA -0.5 -1.5 hypothetical protein (NCBI) compare
b3601 mtlR -0.5 -2.6 DNA-binding repressor (NCBI) compare
b3426 glpD -0.5 -1.3 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1286 rnb -0.5 -1.2 exoribonuclease II (NCBI) compare
b3725 pstB -0.5 -0.3 phosphate transporter subunit (NCBI) compare
b1284 yciT -0.5 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1773 ydjI -0.5 -0.9 predicted aldolase (NCBI) compare
b3002 yqhA -0.5 -1.3 hypothetical protein (NCBI) compare
b2017 yefM -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b2055 wcaE -0.4 -0.3 predicted glycosyl transferase (NCBI) compare
b1461 ydcE -0.4 -1.5 4-oxalocrotonate tautomerase (NCBI) compare
b3026 qseC -0.4 -1.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b2929 yggD -0.4 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2912 ygfA -0.4 -1.4 putative ligase (VIMSS) compare
b3629 rfaS -0.4 -1.4 lipopolysaccharide core biosynthesis protein (NCBI) compare
b4194 ulaB -0.4 -2.0 L-ascorbate-specific enzyme IIB component of PTS (NCBI) compare
b2625 yfjI -0.4 -0.5 CP4-57 prophage; predicted protein (NCBI) compare
b1989 asnV -0.4 -1.4 tRNA-Asn (NCBI) compare
b4494 arpB -0.4 -0.9 no description compare
b1108 ycfP -0.4 -1.5 orf, hypothetical protein (VIMSS) compare
b3792 wzxE -0.4 -2.6 O-antigen translocase (NCBI) compare
b1536 ydeI -0.4 -0.4 hypothetical protein (NCBI) compare
b3281 aroE -0.4 -3.7 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b0641 rlpB -0.4 -0.8 minor lipoprotein (NCBI) compare
b2947 gshB -0.4 -1.6 glutathione synthetase (NCBI) compare
b2074 b2074 -0.4 -2.3 putative membrane protein (VIMSS) compare
b3619 rfaD -0.4 -1.5 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1165 ymgA -0.4 -0.2 hypothetical protein (NCBI) compare
b1129 phoQ -0.4 -0.7 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b0499 ylbH -0.4 -1.7 conserved protein, rhs-like (RefSeq) compare
b3726 pstA -0.4 -2.0 phosphate transporter subunit (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments