| | gene | name | fitness | t score | description | |
|---|
| b4053 | alr | -10.2 | -7.1 | alanine racemase (NCBI) | compare |
| b1855 | lpxM | -9.3 | -4.2 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b1192 | ldcA | -9.2 | -4.3 | L,D-carboxypeptidase A (NCBI) | compare |
| b3035 | tolC | -8.2 | -16.2 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b3839 | tatC | -7.7 | -9.2 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0222 | lpcA | -7.6 | -3.2 | phosphoheptose isomerase (NCBI) | compare |
| b3052 | rfaE | -7.5 | -5.2 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b3620 | rfaF | -7.3 | -5.0 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b3621 | rfaC | -7.0 | -4.8 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b0688 | pgm | -6.9 | -4.0 | phosphoglucomutase (NCBI) | compare |
| b3619 | rfaD | -6.9 | -4.8 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b0740 | tolB | -6.7 | -4.6 | translocation protein TolB precursor (NCBI) | compare |
| b3631 | rfaG | -6.6 | -30.1 | glucosyltransferase I (NCBI) | compare |
| b1236 | galU | -6.4 | -4.4 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b2620 | smpB | -6.4 | -1.8 | SsrA-binding protein (NCBI) | compare |
| b3183 | obgE | -6.3 | -1.8 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b0737 | tolQ | -6.3 | -3.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0739 | tolA | -6.0 | -3.8 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b3613 | yibP | -6.0 | -4.1 | putative membrane protein (VIMSS) | compare |
| b1429 | tehA | -5.9 | -1.5 | potassium-tellurite ethidium and proflavin transporter (NCBI) | compare |
| b1863 | ruvC | -5.7 | -2.4 | Holliday junction resolvase (NCBI) | compare |
| b0738 | tolR | -5.5 | -3.3 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2830 | nudH | -5.5 | -1.9 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b1293 | sapB | -5.5 | -2.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1882 | cheY | -5.1 | -0.7 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b0200 | gmhB | -5.1 | -2.0 | hypothetical protein (NCBI) | compare |
| b1850 | eda | -5.0 | -3.3 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b0741 | pal | -4.7 | -5.2 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b1860 | ruvB | -4.5 | -1.4 | Holliday junction DNA helicase B (NCBI) | compare |
| b0683 | fur | -4.5 | -2.1 | ferric uptake regulator (NCBI) | compare |
| b3405 | ompR | -4.4 | -8.3 | osmolarity response regulator (NCBI) | compare |
| b3261 | fis | -4.2 | -2.4 | DNA-binding protein Fis (NCBI) | compare |
| b3628 | rfaB | -4.2 | -17.1 | UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) | compare |
| b1292 | sapC | -4.1 | -3.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3816 | corA | -4.1 | -12.2 | magnesium/nickel/cobalt transporter (NCBI) | compare |
| b1861 | ruvA | -4.1 | -1.3 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b3741 | gidA | -4.1 | -11.6 | glucose-inhibited division protein A (NCBI) | compare |
| b3811 | xerC | -4.0 | -2.4 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b4375 | prfC | -4.0 | -11.7 | peptide chain release factor 3 (NCBI) | compare |
| b0463 | acrA | -3.9 | -9.9 | multidrug efflux system (NCBI) | compare |
| b4503 | yafF | -3.8 | -0.8 | no description | compare |
| b3979 | thrT | -3.7 | -0.5 | tRNA-Thr (NCBI) | compare |
| b1677 | lpp | -3.7 | -2.4 | murein lipoprotein (NCBI) | compare |
| b3838 | tatB | -3.6 | -7.1 | sec-independent translocase (NCBI) | compare |
| b0890 | ftsK | -3.5 | -9.5 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b2330 | yfcB | -3.4 | -2.3 | putative adenine-specific methylase (VIMSS) | compare |
| b2894 | xerD | -3.4 | -1.1 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b0902 | pflA | -3.3 | -7.1 | pyruvate formate lyase activating enzyme 1 (NCBI) | compare |
| b3792 | wzxE | -3.3 | -9.1 | O-antigen translocase (NCBI) | compare |
| b0053 | surA | -3.2 | -7.1 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b2569 | lepA | -3.2 | -5.5 | GTP-binding protein LepA (NCBI) | compare |
| b1176 | minC | -3.2 | -2.9 | septum formation inhibitor (NCBI) | compare |
| b2934 | cmtB | -3.2 | -0.9 | predicted mannitol-specific enzyme IIA component of PTS (NCBI) | compare |
| b2820 | recB | -3.1 | -1.8 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b1334 | fnr | -3.0 | -2.1 | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | compare |
| b1476 | fdnI | -3.0 | -1.0 | formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) | compare |
| b0949 | uup | -3.0 | -9.3 | fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) | compare |
| b4676 | yoaK | -2.9 | -0.6 | expressed protein (RefSeq) | compare |
| b2567 | rnc | -2.9 | -0.9 | ribonuclease III (NCBI) | compare |
| b4202 | rpsR | -2.9 | -2.1 | 30S ribosomal protein S18 (NCBI) | compare |
| b2846 | yqeH | -2.8 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b3164 | pnp | -2.8 | -2.5 | polynucleotide phosphorylase/polyadenylase (RefSeq) | compare |
| b0145 | dksA | -2.8 | -4.2 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0903 | pflB | -2.8 | -11.3 | pyruvate formate lyase I (NCBI) | compare |
| b4177 | purA | -2.7 | -1.8 | adenylosuccinate synthetase (NCBI) | compare |
| b4042 | dgkA | -2.7 | -3.8 | diacylglycerol kinase (NCBI) | compare |
| b4171 | miaA | -2.7 | -5.1 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b3706 | trmE | -2.7 | -6.0 | tRNA modification GTPase (NCBI) | compare |
| b1175 | minD | -2.7 | -3.4 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b4172 | hfq | -2.6 | -0.9 | RNA-binding protein Hfq (NCBI) | compare |
| b3290 | trkA | -2.6 | -4.7 | potassium transporter peripheral membrane component (NCBI) | compare |
| b2158 | yeiH | -2.6 | -9.8 | conserved inner membrane protein (NCBI) | compare |
| b2297 | pta | -2.5 | -1.0 | phosphate acetyltransferase (NCBI) | compare |
| b3778 | rep | -2.5 | -8.5 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b3386 | rpe | -2.5 | -1.3 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b3627 | rfaI | -2.4 | -9.8 | UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) | compare |
| b1258 | yciF | -2.4 | -0.9 | hypothetical protein (NCBI) | compare |
| b2188 | yejM | -2.4 | -7.2 | predicted hydrolase, inner membrane (NCBI) | compare |
| b1130 | phoP | -2.4 | -2.5 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b3961 | oxyR | -2.4 | -9.2 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1241 | adhE | -2.4 | -9.7 | fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) | compare |
| b3916 | pfkA | -2.3 | -3.5 | 6-phosphofructokinase (NCBI) | compare |
| b2285 | nuoE | -2.3 | -2.2 | NADH dehydrogenase subunit E (NCBI) | compare |
| b3836 | b3836 | -2.3 | -2.5 | orf, hypothetical protein (VIMSS) | compare |
| b4155 | yjeA | -2.3 | -1.0 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b4701 | sokX | -2.2 | -1.2 | sok-related sRNA, function unknown (RefSeq) | compare |
| b3933 | ftsN | -2.2 | -7.5 | essential cell division protein (NCBI) | compare |
| b4203 | rplI | -2.2 | -3.9 | 50S ribosomal protein L9 (NCBI) | compare |
| b2288 | nuoA | -2.2 | -3.2 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b2822 | recC | -2.2 | -6.6 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b0658 | ybeX | -2.1 | -1.4 | predicteed ion transport (NCBI) | compare |
| b2279 | nuoK | -2.1 | -1.4 | NADH dehydrogenase subunit K (NCBI) | compare |
| b2318 | truA | -2.1 | -2.7 | tRNA pseudouridine synthase A (NCBI) | compare |
| b3867 | hemN | -2.1 | -11.6 | O2-independent coproporphyrinogen III oxidase (VIMSS) | compare |
| b2699 | recA | -2.0 | -1.9 | recombinase A (NCBI) | compare |
| b3623 | rfaK | -2.0 | -3.6 | lipopolysaccharide core biosynthesis (NCBI) | compare |
| b0462 | acrB | -2.0 | -12.3 | multidrug efflux system protein (NCBI) | compare |
| b2329 | aroC | -2.0 | -5.7 | chorismate synthase (NCBI) | compare |
| b1536 | ydeI | -2.0 | -1.0 | hypothetical protein (NCBI) | compare |
| b3935 | priA | -2.0 | -2.7 | primosome assembly protein PriA (NCBI) | compare |
| b1161 | ycgX | -2.0 | -0.5 | hypothetical protein (NCBI) | compare |
| b2476 | purC | -2.0 | -2.2 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0439 | lon | -1.9 | -4.5 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0014 | dnaK | -1.9 | -1.9 | molecular chaperone DnaK (NCBI) | compare |
| b4593 | ymgI | -1.9 | -1.0 | hypothetical protein (RefSeq) | compare |
| b4201 | priB | -1.9 | -1.8 | primosomal replication protein N (NCBI) | compare |
| b3842 | rfaH | -1.9 | -5.4 | transcriptional activator RfaH (NCBI) | compare |
| b4179 | vacB | -1.8 | -6.5 | putative enzyme (VIMSS) | compare |
| b3725 | pstB | -1.8 | -2.5 | phosphate transporter subunit (NCBI) | compare |
| b4146 | yjeK | -1.8 | -2.6 | predicted lysine aminomutase (NCBI) | compare |
| b3728 | pstS | -1.8 | -4.2 | phosphate transporter subunit (NCBI) | compare |
| b1279 | yciS | -1.8 | -1.0 | conserved inner membrane protein (NCBI) | compare |
| b1159 | mcrA | -1.8 | -0.7 | e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) | compare |
| b3636 | rpmG | -1.7 | -2.0 | 50S ribosomal protein L33 (NCBI) | compare |
| b0161 | degP | -1.7 | -4.9 | serine endoprotease (protease Do), membrane-associated (NCBI) | compare |
| b0114 | aceE | -1.7 | -2.7 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b3658 | selC | -1.7 | -3.4 | tRNA-Sec (NCBI) | compare |
| b3652 | recG | -1.7 | -7.3 | ATP-dependent DNA helicase (NCBI) | compare |
| b4025 | pgi | -1.7 | -6.2 | glucose-6-phosphate isomerase (NCBI) | compare |
| b3629 | rfaS | -1.7 | -4.6 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b1818 | manY | -1.7 | -1.7 | mannose-specific enzyme IIC component of PTS (NCBI) | compare |
| b3624 | rfaZ | -1.6 | -3.8 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b0386 | proC | -1.6 | -4.0 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b0401 | brnQ | -1.6 | -8.7 | predicted branched chain amino acid transporter (LIV-II) (NCBI) | compare |
| b3863 | polA | -1.6 | -1.3 | DNA polymerase I (NCBI) | compare |
| b4402 | yjjY | -1.6 | -0.9 | hypothetical protein (NCBI) | compare |
| b0019 | nhaA | -1.6 | -7.8 | pH-dependent sodium/proton antiporter (NCBI) | compare |
| b2576 | srmB | -1.6 | -2.6 | ATP-dependent RNA helicase (NCBI) | compare |
| b3032 | cpdA | -1.6 | -6.2 | cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) | compare |
| b0088 | murD | -1.6 | -1.4 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b2040 | rfbD | -1.6 | -7.9 | dTDP-4-dehydrorhamnose reductase subunit, NAD(P)-binding, of dTDP-L-rhamnose synthase (NCBI) | compare |
| b1278 | pgpB | -1.6 | -1.8 | phosphatidylglycerophosphatase B (NCBI) | compare |
| b4243 | yjgF | -1.6 | -4.7 | orf, hypothetical protein (VIMSS) | compare |
| b3462 | ftsX | -1.6 | -8.6 | predicted transporter subunit: membrane component of ABC superfamily (NCBI) | compare |
| b2935 | tktA | -1.6 | -2.7 | transketolase 1, thiamin-binding (NCBI) | compare |
| b2501 | ppk | -1.6 | -6.6 | polyphosphate kinase (NCBI) | compare |
| b4655 | ythA | -1.5 | -1.0 | expressed protein (RefSeq) | compare |
| b1545 | pinQ | -1.5 | -0.2 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b3404 | envZ | -1.5 | -6.5 | osmolarity sensor protein (NCBI) | compare |
| b0677 | nagA | -1.5 | -4.5 | N-acetylglucosamine-6-phosphate deacetylase (NCBI) | compare |
| b2808 | gcvA | -1.5 | -2.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3210 | arcB | -1.5 | -5.3 | hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) | compare |
| b0678 | nagB | -1.5 | -3.1 | glucosamine-6-phosphate deaminase (NCBI) | compare |
| b3612 | gpmI | -1.5 | -10.5 | phosphoglyceromutase (NCBI) | compare |
| b3726 | pstA | -1.5 | -4.4 | phosphate transporter subunit (NCBI) | compare |
| b1286 | rnb | -1.5 | -1.6 | exoribonuclease II (NCBI) | compare |
| b0523 | purE | -1.5 | -3.6 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b0406 | tgt | -1.5 | -5.0 | queuine tRNA-ribosyltransferase (NCBI) | compare |
| b1773 | ydjI | -1.5 | -3.3 | predicted aldolase (NCBI) | compare |
| b0746 | valZ | -1.5 | -2.2 | tRNA-Val (NCBI) | compare |
| b0784 | moaD | -1.4 | -2.6 | molybdopterin synthase, small subunit (NCBI) | compare |
| b0015 | dnaJ | -1.4 | -5.2 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b0908 | aroA | -1.4 | -6.0 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2038 | rfbC | -1.4 | -6.2 | dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) | compare |
| b4477 | dgoA | -1.4 | -2.3 | 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (NCBI) | compare |
| b4178 | yjeB | -1.4 | -5.4 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b4651 | yibW | -1.4 | -0.4 | no description | compare |
| b1600 | mdtJ | -1.4 | -1.9 | multidrug efflux system transporter (NCBI) | compare |
| b2284 | nuoF | -1.4 | -3.9 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b0759 | galE | -1.4 | -4.0 | UDP-galactose-4-epimerase (VIMSS) | compare |
| b1506 | yneL | -1.4 | -1.4 | predicted transcriptional regulator (NCBI) | compare |
| b0143 | pcnB | -1.4 | -4.3 | poly(A) polymerase I (VIMSS) | compare |
| b3341 | rpsG | -1.4 | -0.8 | 30S ribosomal protein S7 (NCBI) | compare |
| b4048 | yjbM | -1.4 | -1.7 | hypothetical protein (NCBI) | compare |
| b4066 | yjcF | -1.4 | -0.4 | hypothetical protein (NCBI) | compare |
| b4481 | rffT | -1.3 | -5.3 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3120 | yhaB | -1.3 | -1.4 | orf, hypothetical protein (VIMSS) | compare |
| b4502 | yeiW | -1.3 | -2.5 | hypothetical protein (NCBI) | compare |
| b0296 | ykgM | -1.3 | -1.4 | 50S ribosomal protein L31 (NCBI) | compare |
| b2209 | eco | -1.3 | -1.4 | ecotin precursor (NCBI) | compare |
| b1251 | yciI | -1.3 | -2.6 | orf, hypothetical protein (VIMSS) | compare |
| b1074 | flgC | -1.3 | -1.9 | flagellar basal-body rod protein C (NCBI) | compare |
| b1095 | fabF | -1.3 | -4.6 | 3-oxoacyl-(acyl carrier protein) synthase (NCBI) | compare |
| b1196 | ycgY | -1.3 | -2.0 | hypothetical protein (NCBI) | compare |
| b0623 | cspE | -1.3 | -1.7 | cold shock protein E (NCBI) | compare |
| b4191 | ulaR | -1.3 | -3.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0706 | ybfD | -1.3 | -2.1 | hypothetical protein (NCBI) | compare |
| b2313 | cvpA | -1.3 | -3.5 | membrane protein required for colicin V production (NCBI) | compare |
| b3600 | mtlD | -1.3 | -5.3 | mannitol-1-phosphate 5-dehydrogenase (NCBI) | compare |
| b1125 | potB | -1.3 | -2.7 | spermidine/putrescine ABC transporter membrane protein (NCBI) | compare |
| b3082 | ygjM | -1.3 | -1.2 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3463 | ftsE | -1.3 | -0.9 | predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) | compare |
| b3162 | deaD | -1.3 | -3.2 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b3609 | secB | -1.2 | -3.6 | export protein SecB (NCBI) | compare |
| b0239 | frsA | -1.2 | -5.5 | fermentation/respiration switch protein (NCBI) | compare |
| b2064 | asmA | -1.2 | -4.7 | predicted assembly protein (NCBI) | compare |
| b2564 | pdxJ | -1.2 | -1.8 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b3229 | sspA | -1.2 | -2.5 | stringent starvation protein A (NCBI) | compare |
| b0149 | mrcB | -1.2 | -6.7 | penicillin-binding protein 1b (NCBI) | compare |
| b0763 | modA | -1.2 | -3.6 | molybdate transporter subunit (NCBI) | compare |
| b4407 | thiS | -1.2 | -1.4 | sulfur carrier protein ThiS (NCBI) | compare |
| b2081 | yegQ | -1.2 | -5.8 | predicted peptidase (NCBI) | compare |
| b0904 | focA | -1.2 | -3.3 | formate transporter (NCBI) | compare |
| b1213 | ychQ | -1.2 | -3.0 | predicted transcriptional regulator (NCBI) | compare |
| b4547 | ypfN | -1.2 | -1.2 | hypothetical protein (NCBI) | compare |
| b2248 | yfaX | -1.2 | -1.3 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1830 | prc | -1.2 | -4.0 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b0472 | recR | -1.2 | -4.7 | recombination protein RecR (NCBI) | compare |
| b1025 | ycdT | -1.2 | -1.6 | predicted diguanylate cyclase (NCBI) | compare |
| b3649 | rpoZ | -1.2 | -2.7 | DNA-directed RNA polymerase subunit omega (NCBI) | compare |