Experiment set33IT065 for Escherichia coli BW25113

Compare to:

20 hr rep1_No_BD100_grewON

200 most important genes:

  gene name fitness t score description  
b3961 oxyR -8.4 -11.6 DNA-binding transcriptional dual regulator (NCBI) compare
b2620 smpB -5.1 -2.5 SsrA-binding protein (NCBI) compare
b3183 obgE -4.5 -2.2 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2567 rnc -3.0 -1.6 ribonuclease III (NCBI) compare
b2912 ygfA -3.0 -6.1 putative ligase (VIMSS) compare
b0200 gmhB -3.0 -2.8 hypothetical protein (NCBI) compare
b0222 lpcA -3.0 -5.2 phosphoheptose isomerase (NCBI) compare
b0439 lon -2.8 -8.6 DNA-binding ATP-dependent protease La (NCBI) compare
b1192 ldcA -2.8 -5.2 L,D-carboxypeptidase A (NCBI) compare
b3341 rpsG -2.6 -1.7 30S ribosomal protein S7 (NCBI) compare
b3621 rfaC -2.6 -9.1 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0049 apaH -2.6 -5.9 diadenosinetetraphosphatase (NCBI) compare
b0142 folK -2.5 -0.8 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b3162 deaD -2.4 -8.2 inducible ATP-independent RNA helicase (VIMSS) compare
b1860 ruvB -2.3 -1.9 Holliday junction DNA helicase B (NCBI) compare
b3052 rfaE -2.1 -6.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0738 tolR -2.1 -4.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2330 yfcB -2.1 -2.5 putative adenine-specific methylase (VIMSS) compare
b1187 fadR -2.1 -4.1 fatty acid metabolism regulator (NCBI) compare
b3761 trpT -2.1 -1.9 tRNA-Trp (NCBI) compare
b4375 prfC -2.1 -7.5 peptide chain release factor 3 (NCBI) compare
b3619 rfaD -2.1 -5.8 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0726 sucA -2.0 -4.7 alpha-ketoglutarate decarboxylase (NCBI) compare
b3390 aroK -2.0 -3.2 shikimate kinase I (NCBI) compare
b3261 fis -2.0 -3.7 DNA-binding protein Fis (NCBI) compare
b1292 sapC -2.0 -2.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2830 nudH -1.9 -2.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b0630 lipB -1.9 -2.8 protein of lipoate biosynthesis (VIMSS) compare
b1236 galU -1.9 -5.9 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1863 ruvC -1.9 -2.5 Holliday junction resolvase (NCBI) compare
b2297 pta -1.9 -2.0 phosphate acetyltransferase (NCBI) compare
b0890 ftsK -1.9 -8.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1575 dicB -1.8 -2.1 Qin prophage; cell division inhibition protein (NCBI) compare
b2518 ndk -1.8 -3.8 nucleoside diphosphate kinase (NCBI) compare
b1252 tonB -1.8 -3.1 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b0688 pgm -1.8 -4.6 phosphoglucomutase (NCBI) compare
b1551 b1551 -1.8 -0.8 orf, hypothetical protein (VIMSS) compare
b4042 dgkA -1.7 -3.5 diacylglycerol kinase (NCBI) compare
b2168 fruK -1.7 -1.8 1-phosphofructokinase (NCBI) compare
b1712 ihfA -1.7 -2.6 integration host factor subunit alpha (NCBI) compare
b1865 nudB -1.6 -1.8 dATP pyrophosphohydrolase (NCBI) compare
b1850 eda -1.6 -1.8 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b1058 yceO -1.6 -0.5 hypothetical protein (NCBI) compare
b2820 recB -1.5 -2.6 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3620 rfaF -1.5 -5.0 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b4647 mokA -1.5 -1.0 no description compare
b3631 rfaG -1.5 -11.6 glucosyltransferase I (NCBI) compare
b1165 ymgA -1.5 -0.9 hypothetical protein (NCBI) compare
b0990 cspG -1.5 -1.5 DNA-binding transcriptional regulator (NCBI) compare
b0888 trxB -1.5 -4.5 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3778 rep -1.5 -8.0 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2937 speB -1.5 -7.0 agmatinase (NCBI) compare
b3198 kdsC -1.5 -3.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3630 rfaP -1.5 -10.1 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b4163 glyV -1.4 -1.5 tRNA-Gly (NCBI) compare
b3237 argR -1.4 -4.4 arginine repressor (NCBI) compare
b2822 recC -1.4 -5.8 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b3500 gor -1.4 -2.1 glutathione reductase (NCBI) compare
b2894 xerD -1.4 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b0232 yafN -1.4 -0.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3414 gntY -1.4 -5.2 predicted gluconate transport associated protein (NCBI) compare
b3741 gidA -1.4 -6.3 glucose-inhibited division protein A (NCBI) compare
b0683 fur -1.4 -1.2 ferric uptake regulator (NCBI) compare
b2576 srmB -1.3 -3.1 ATP-dependent RNA helicase (NCBI) compare
b0843 ybjH -1.3 -3.0 hypothetical protein (NCBI) compare
b2479 gcvR -1.3 -5.4 transcriptional regulation of gcv operon (VIMSS) compare
b0101 yacG -1.3 -3.7 zinc-binding protein (NCBI) compare
b3229 sspA -1.3 -3.6 stringent starvation protein A (NCBI) compare
b2498 upp -1.3 -3.6 uracil phosphoribosyltransferase (VIMSS) compare
b3405 ompR -1.3 -4.2 osmolarity response regulator (NCBI) compare
b4702 mgtL -1.3 -2.1 regulatory leader peptide for mgtA (NCBI) compare
b0739 tolA -1.3 -3.6 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3842 rfaH -1.3 -5.0 transcriptional activator RfaH (NCBI) compare
b2699 recA -1.3 -1.8 recombinase A (NCBI) compare
b0605 ahpC -1.3 -2.7 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1676 pykF -1.3 -3.1 pyruvate kinase (NCBI) compare
b3493 pitA -1.3 -7.1 phosphate transporter, low-affinity (NCBI) compare
b4414 tff -1.2 -1.4 unknown RNA (NCBI) compare
b3002 yqhA -1.2 -0.8 hypothetical protein (NCBI) compare
b1363 trkG -1.2 -0.8 Rac prophage; potassium transporter subunit (NCBI) compare
b4571 wbbL -1.2 -3.3 no description compare
b4146 yjeK -1.2 -3.1 predicted lysine aminomutase (NCBI) compare
b1001 yccE -1.2 -0.6 hypothetical protein (NCBI) compare
b1048 mdoG -1.2 -4.9 glucan biosynthesis protein, periplasmic (NCBI) compare
b0178 hlpA -1.2 -2.5 periplasmic chaperone (NCBI) compare
b3728 pstS -1.1 -3.2 phosphate transporter subunit (NCBI) compare
b1499 ydeO -1.1 -0.6 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1724 ydiZ -1.1 -1.6 hypothetical protein (NCBI) compare
b3811 xerC -1.1 -2.1 site-specific tyrosine recombinase XerC (NCBI) compare
b2569 lepA -1.1 -4.5 GTP-binding protein LepA (NCBI) compare
b1257 yciE -1.1 -0.5 hypothetical protein (NCBI) compare
b3706 trmE -1.1 -4.4 tRNA modification GTPase (NCBI) compare
b1600 mdtJ -1.1 -2.3 multidrug efflux system transporter (NCBI) compare
b4535 yniD -1.1 -1.3 predicted protein (RefSeq) compare
b3609 secB -1.1 -3.3 export protein SecB (NCBI) compare
b4697 yrdF -1.1 -2.9 no description compare
b4155 yjeA -1.1 -0.7 putative lysyl-tRNA synthetase (VIMSS) compare
b3870 glnA -1.1 -2.5 glutamine synthetase (NCBI) compare
b0099 mutT -1.1 -2.8 nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP (NCBI) compare
b3169 nusA -1.1 -2.0 transcription elongation factor NusA (NCBI) compare
b4685 yrbN -1.1 -1.9 expressed protein (RefSeq) compare
b0767 ybhE -1.1 -3.3 6-phosphogluconolactonase (NCBI) compare
b0737 tolQ -1.1 -2.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1291 sapD -1.1 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4184 yjfL -1.1 -4.3 conserved inner membrane protein (NCBI) compare
b1708 nlpC -1.1 -2.2 predicted lipoprotein (NCBI) compare
b2808 gcvA -1.1 -3.7 DNA-binding transcriptional dual regulator (NCBI) compare
b2935 tktA -1.1 -2.4 transketolase 1, thiamin-binding (NCBI) compare
b0114 aceE -1.1 -1.8 pyruvate dehydrogenase subunit E1 (NCBI) compare
b3600 mtlD -1.1 -5.0 mannitol-1-phosphate 5-dehydrogenase (NCBI) compare
b0658 ybeX -1.1 -0.7 predicteed ion transport (NCBI) compare
b1635 gst -1.1 -2.7 glutathionine S-transferase (NCBI) compare
b0741 pal -1.1 -3.6 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2058 wcaB -1.0 -1.0 predicted acyl transferase (NCBI) compare
b1963 b1963 -1.0 -2.7 orf, hypothetical protein (VIMSS) compare
b1182 hlyE -1.0 -0.6 hemolysin E (VIMSS) compare
b3164 pnp -1.0 -2.4 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2456 cchB -1.0 -3.8 predicted carboxysome structural protein, ethanolamine utilization protein (NCBI) compare
b0827 moeA -1.0 -3.5 molybdopterin biosynthesis protein (NCBI) compare
b0438 clpX -1.0 -5.2 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1025 ycdT -1.0 -1.5 predicted diguanylate cyclase (NCBI) compare
b1290 sapF -1.0 -1.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0740 tolB -1.0 -3.2 translocation protein TolB precursor (NCBI) compare
b0729 sucD -1.0 -2.2 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3463 ftsE -1.0 -1.4 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4045 yjbJ -1.0 -2.2 predicted stress response protein (NCBI) compare
b2528 iscA -1.0 -1.0 iron-sulfur cluster assembly protein (NCBI) compare
b3781 trxA -1.0 -2.6 thioredoxin 1 (VIMSS) compare
b2276 nuoN -1.0 -3.8 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b1084 rne -1.0 -4.8 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b4441 glmY -0.9 -1.3 sRNA activator of glmS mRNA (RefSeq) compare
b3979 thrT -0.9 -0.3 tRNA-Thr (NCBI) compare
b3871 bipA -0.9 -6.3 GTP-binding protein (NCBI) compare
b0720 gltA -0.9 -3.7 citrate synthase (NCBI) compare
b2318 truA -0.9 -2.7 tRNA pseudouridine synthase A (NCBI) compare
b1183 umuD -0.9 -1.5 DNA polymerase V, subunit D (NCBI) compare
b2017 yefM -0.9 -1.2 orf, hypothetical protein (VIMSS) compare
b1576 ydfD -0.9 -0.4 Qin prophage; predicted protein (NCBI) compare
b4640 yoeG -0.9 -3.3 no description compare
b1361 ydaW -0.9 -0.4 orf, hypothetical protein (VIMSS) compare
b4172 hfq -0.9 -0.7 RNA-binding protein Hfq (NCBI) compare
b0082 mraW -0.9 -3.1 S-adenosyl-methyltransferase (NCBI) compare
b3636 rpmG -0.9 -1.2 50S ribosomal protein L33 (NCBI) compare
b3204 ptsN -0.9 -3.4 sugar-specific enzyme IIA component of PTS (NCBI) compare
b4407 thiS -0.9 -1.5 sulfur carrier protein ThiS (NCBI) compare
b1855 lpxM -0.9 -2.9 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3650 spoT -0.9 -3.9 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b3290 trkA -0.9 -2.1 potassium transporter peripheral membrane component (NCBI) compare
b1138 ymfE -0.9 -1.1 e14 prophage; predicted inner membrane protein (NCBI) compare
b0145 dksA -0.9 -2.3 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0471 ybaB -0.9 -1.8 hypothetical protein (NCBI) compare
b2282 nuoH -0.9 -2.2 NADH dehydrogenase subunit H (NCBI) compare
b1497 b1497 -0.9 -0.7 putative enzyme (VIMSS) compare
b1664 ydhQ -0.9 -2.8 hypothetical protein (NCBI) compare
b2277 nuoM -0.9 -3.9 NADH dehydrogenase subunit M (NCBI) compare
b1804 rnd -0.9 -3.7 ribonuclease D (NCBI) compare
b3725 pstB -0.9 -1.0 phosphate transporter subunit (NCBI) compare
b0437 clpP -0.9 -3.4 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b1936 intG -0.8 -0.8 predicted defective phage integrase (pseudogene) (RefSeq) compare
b2564 pdxJ -0.8 -2.4 pyridoxal phosphate biosynthetic protein (NCBI) compare
b1179 ycgL -0.8 -1.9 conserved protein (NCBI) compare
b3916 pfkA -0.8 -2.3 6-phosphofructokinase (NCBI) compare
b2071 yegJ -0.8 -1.5 hypothetical protein (NCBI) compare
b1423 ydcJ -0.8 -2.3 hypothetical protein (NCBI) compare
b1536 ydeI -0.8 -1.4 hypothetical protein (NCBI) compare
b3035 tolC -0.8 -4.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b1730 ydjO -0.8 -0.9 predicted protein (RefSeq) compare
b3613 yibP -0.8 -3.0 putative membrane protein (VIMSS) compare
b1545 pinQ -0.8 -0.1 Qin prophage; predicted site-specific recombinase (NCBI) compare
b2688 gshA -0.8 -4.5 glutamate--cysteine ligase (NCBI) compare
b1908 yecA -0.8 -2.4 conserved metal-binding protein (NCBI) compare
b2424 cysU -0.8 -1.9 sulfate/thiosulfate transporter subunit (NCBI) compare
b2113 mrp -0.8 -2.9 putative ATPase (VIMSS) compare
b2698 recX -0.8 -1.8 RecA regulator RecX (NCBI) compare
b0051 ksgA -0.8 -3.3 dimethyladenosine transferase (NCBI) compare
b2288 nuoA -0.8 -1.9 NADH dehydrogenase I chain A (VIMSS) compare
b0585 fes -0.8 -3.9 enterobactin/ferric enterobactin esterase (NCBI) compare
b2207 napD -0.8 -1.8 assembly protein for periplasmic nitrate reductase (NCBI) compare
b1444 ydcW -0.8 -2.7 medium chain aldehyde dehydrogenase (NCBI) compare
b4648 ysaC -0.8 -1.6 no description compare
b1984 asnW -0.8 -0.8 tRNA-Asn (NCBI) compare
b1258 yciF -0.8 -1.0 hypothetical protein (NCBI) compare
b2198 ccmD -0.8 -1.4 cytochrome c biogenesis protein (NCBI) compare
b1999 yeeP -0.8 -2.6 putative histone (VIMSS) compare
b4012 yjaB -0.8 -1.3 predicted acetyltransferase (NCBI) compare
b2150 mglB -0.8 -2.7 methyl-galactoside transporter subunit (NCBI) compare
b4171 miaA -0.8 -2.2 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3210 arcB -0.8 -4.7 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b3623 rfaK -0.8 -2.2 lipopolysaccharide core biosynthesis (NCBI) compare
b1709 btuD -0.8 -0.8 vitamin B12-transporter ATPase (NCBI) compare
b4503 yafF -0.8 -0.5 no description compare
b2286 nuoC -0.8 -2.3 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0721 sdhC -0.8 -1.9 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b2501 ppk -0.8 -4.5 polyphosphate kinase (NCBI) compare
b1196 ycgY -0.8 -2.4 hypothetical protein (NCBI) compare
b2281 nuoI -0.8 -1.5 NADH dehydrogenase subunit I (NCBI) compare
b3726 pstA -0.7 -3.0 phosphate transporter subunit (NCBI) compare
b0722 sdhD -0.7 -2.4 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b2625 yfjI -0.7 -1.5 CP4-57 prophage; predicted protein (NCBI) compare
b3617 kbl -0.7 -3.9 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in control experiments