Experiment set33IT044 for Escherichia coli BW25113

Compare to:

3 hr rep2_HD100_10fold_dilution_grewON

200 most detrimental genes:

  gene name fitness t score description  
b1400 paaY +1.0 4.3 predicted hexapeptide repeat acetyltransferase (NCBI) compare
b1550 b1550 +1.0 2.2 orf, hypothetical protein (VIMSS) compare
b4545 ypdJ +0.9 2.7 no description compare
b1942 fliJ +0.8 1.9 flagellar biosynthesis chaperone (NCBI) compare
b1382 ynbE +0.7 1.7 predicted lipoprotein (NCBI) compare
b4418 sraB +0.7 2.0 unknown RNA (NCBI) compare
b1789 yeaL +0.6 2.9 conserved inner membrane protein (NCBI) compare
b1593 b1593 +0.6 2.2 orf, hypothetical protein (VIMSS) compare
b0998 torD +0.6 1.2 chaperone protein TorD (NCBI) compare
b2934 cmtB +0.6 0.8 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b1609 rstB +0.6 2.4 sensory histidine kinase in two-component regulatory system with RstA (NCBI) compare
b0142 folK +0.6 0.7 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1370 insH-5 +0.6 2.0 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b0564 appY +0.6 0.8 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1434 ydcN +0.6 1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1591 b1591 +0.6 1.8 putative oxidoreductase component (VIMSS) compare
b0989 cspH +0.6 2.0 stress protein, member of the CspA-family (NCBI) compare
b1418 cybB +0.5 1.8 cytochrome b(561) (VIMSS) compare
b1949 fliQ +0.5 1.9 flagellar biosynthesis protein Q (NCBI) compare
b4181 yjfI +0.5 1.9 hypothetical protein (NCBI) compare
b1520 b1520 +0.5 2.0 orf, hypothetical protein (VIMSS) compare
b2096 gatY +0.5 2.8 tagatose-bisphosphate aldolase 1 (VIMSS) compare
b0707 ybgA +0.5 2.2 hypothetical protein (NCBI) compare
b1642 slyA +0.5 1.7 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b0210 yafE +0.5 2.6 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b2450 yffS +0.5 1.8 CPZ-55 prophage; predicted protein (RefSeq) compare
b1070 flgN +0.5 1.0 export chaperone for FlgK and FlgL (NCBI) compare
b2448 yffQ +0.5 1.8 CPZ-55 prophage; predicted protein (RefSeq) compare
b0682 ybfN +0.5 1.9 predicted lipoprotein (NCBI) compare
b1560 ydfU +0.5 1.7 Qin prophage; predicted protein (RefSeq) compare
b0843 ybjH +0.5 1.7 hypothetical protein (NCBI) compare
b1358 ydaT +0.5 1.0 Rac prophage; predicted protein (NCBI) compare
b4041 plsB +0.5 1.5 glycerol-3-phosphate acyltransferase (VIMSS) compare
b4011 yjaA +0.5 1.6 hypothetical protein (NCBI) compare
b2659 b2659 +0.5 1.9 orf, hypothetical protein (VIMSS) compare
b2410 yfeH +0.5 2.4 predicted inner membrane protein (NCBI) compare
b1348 lar +0.5 1.6 Rac prophage; restriction alleviation protein (NCBI) compare
b4642 yoeD +0.5 1.4 no description compare
b2783 chpR +0.5 1.9 antitoxin of the ChpA-ChpR toxin-antitoxin system (NCBI) compare
b1523 yneG +0.4 1.4 hypothetical protein (NCBI) compare
b4552 yrhC +0.4 0.7 no description compare
b4578 insP +0.4 1.6 no description compare
b1953 b1953 +0.4 2.1 orf, hypothetical protein (VIMSS) compare
b4529 ydbJ +0.4 0.7 hypothetical protein (NCBI) compare
b4551 yheV +0.4 1.9 hypothetical protein (NCBI) compare
b1540 ydfH +0.4 1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1429 tehA +0.4 0.4 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1765 ydjA +0.4 0.6 predicted oxidoreductase (NCBI) compare
b3545 proK +0.4 1.6 tRNA-Pro (NCBI) compare
b1819 manZ +0.4 1.9 mannose-specific enzyme IID component of PTS (NCBI) compare
b1476 fdnI +0.4 0.7 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b1219 ychN +0.4 2.5 hypothetical protein (NCBI) compare
b4582 yoeA +0.4 2.4 no description compare
b0934 ycbM +0.4 1.7 putative transport system permease protein (VIMSS) compare
b2195 ccmG +0.4 1.6 periplasmic thioredoxin of cytochrome c-type biogenesis (NCBI) compare
b0870 ltaE +0.4 2.9 L-allo-threonine aldolase, PLP-dependent (NCBI) compare
b2083 yegZ +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b1640 ydhH +0.4 2.2 anhydro-N-acetylmuramic acid kinase (NCBI) compare
b1595 ynfL +0.4 1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1119 nagK +0.4 1.7 N-acetyl-D-glucosamine kinase (NCBI) compare
b4698 mgrR +0.4 2.0 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b2642 yfjW +0.4 0.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b0001 thrL +0.4 0.9 thr operon leader peptide (NCBI) compare
b4568 ytjA +0.4 1.3 predicted protein (RefSeq) compare
b0706 ybfD +0.4 1.4 hypothetical protein (NCBI) compare
b1778 yeaA +0.4 1.6 methionine sulfoxide reductase B (NCBI) compare
b1853 yebK +0.4 1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b2171 yeiP +0.4 1.7 putative elongation factor (VIMSS) compare
b0822 ybiV +0.4 2.2 predicted hydrolase (NCBI) compare
b3074 ygjH +0.4 1.9 hypothetical protein (NCBI) compare
b0929 ompF +0.4 2.2 outer membrane porin 1a (Ia;b;F) (NCBI) compare
b1108 ycfP +0.4 1.3 orf, hypothetical protein (VIMSS) compare
b0487 cueR +0.4 2.0 DNA-binding transcriptional activator of copper-responsive regulon genes (NCBI) compare
b4406 yaeP +0.4 1.2 hypothetical protein (NCBI) compare
b3354 yheU +0.4 2.2 hypothetical protein (NCBI) compare
b4566 yjhX +0.4 2.1 hypothetical protein (NCBI) compare
b1672 ydhW +0.4 2.2 hypothetical protein (NCBI) compare
b1758 b1758 +0.4 0.7 putative cytochrome oxidase (VIMSS) compare
b1753 ynjA +0.4 0.9 hypothetical protein (NCBI) compare
b0852 rimK +0.4 2.6 ribosomal protein S6 modification protein (NCBI) compare
b3484 yhhI +0.4 1.4 predicted transposase (NCBI) compare
b3059 ygiH +0.4 2.1 hypothetical protein (NCBI) compare
b1025 ycdT +0.4 0.9 predicted diguanylate cyclase (NCBI) compare
b2939 yqgB +0.4 1.0 predicted protein (RefSeq) compare
b1448 yncA +0.4 1.4 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b4646 yrdE +0.4 2.1 no description compare
b1829 htpX +0.4 2.2 heat shock protein HtpX (NCBI) compare
b2038 rfbC +0.4 2.5 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b1617 uidA +0.3 1.9 beta-D-glucuronidase (NCBI) compare
b1333 uspE +0.3 1.3 stress-induced protein (NCBI) compare
b1253 yciA +0.3 1.1 predicted hydrolase (NCBI) compare
b1153 ymfQ +0.3 1.5 e14 prophage; conserved protein (NCBI) compare
b4704 arrS +0.3 0.1 Antisense sRNA ArrS, function unknown (NCBI) compare
b1742 b1742 +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b2504 yfgG +0.3 0.7 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b0263 afuB +0.3 1.5 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b1892 flhD +0.3 1.8 DNA-binding transcriptional dual regulator with FlhC (RefSeq) compare
b1134 ymfB +0.3 0.9 bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase (NCBI) compare
b4477 dgoA +0.3 1.8 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (NCBI) compare
b4416 rybA +0.3 0.8 unknown RNA (NCBI) compare
b0579 ybdF +0.3 1.7 hypothetical protein (NCBI) compare
b4522 yciX_1 +0.3 1.4 hypothetical protein (NCBI) compare
b1948 fliP +0.3 1.9 flagellar biosynthesis protein P (NCBI) compare
b1519 tam +0.3 1.5 trans-aconitate 2-methyltransferase (NCBI) compare
b0122 yacC +0.3 2.3 orf, hypothetical protein (VIMSS) compare
b1332 ynaJ +0.3 0.3 predicted inner membrane protein (NCBI) compare
b4128 yjdK +0.3 0.5 hypothetical protein (NCBI) compare
b3483 yhhH +0.3 0.1 orf, hypothetical protein (VIMSS) compare
b1618 uidR +0.3 0.8 DNA-binding transcriptional repressor (NCBI) compare
b1226 narJ +0.3 2.1 molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 (NCBI) compare
b1105 ycfM +0.3 1.2 predicted outer membrane lipoprotein (NCBI) compare
b0897 ycaC +0.3 1.8 predicted hydrolase (NCBI) compare
b1818 manY +0.3 0.9 mannose-specific enzyme IIC component of PTS (NCBI) compare
b3280 yrdB +0.3 1.7 hypothetical protein (NCBI) compare
b1922 fliA +0.3 1.9 flagellar biosynthesis; alternative sigma factor 28; regulation of flagellar operons (VIMSS) compare
b1960 vsr +0.3 2.0 DNA mismatch endonuclease of very short patch repair (NCBI) compare
b1282 yciH +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b1141 ymfG +0.3 1.4 e14 prophage; predicted excisionase (NCBI) compare
b4519 icdC +0.3 2.0 no description compare
b0164 yaeI +0.3 1.9 orf, hypothetical protein (VIMSS) compare
b0381 ddlA +0.3 2.1 D-alanylalanine synthetase (NCBI) compare
b4438 cyaR +0.3 1.3 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b1698 ydiR +0.3 1.2 predicted electron transfer flavoprotein, FAD-binding (NCBI) compare
b3644 yicC +0.3 1.9 hypothetical protein (NCBI) compare
b1822 rrmA +0.3 1.0 23S rRNA m1G745 methyltransferase (NCBI) compare
b0655 gltI +0.3 1.4 glutamate and aspartate transporter subunit (NCBI) compare
b4453 ldrD +0.3 1.0 toxic polypeptide, small (NCBI) compare
b1189 dadA +0.3 2.0 D-amino acid dehydrogenase (quinone) DadA (EC 1.4.5.1) (from data) compare
b2309 hisJ +0.3 1.2 histidine/lysine/arginine/ornithine transporter subunit (NCBI) compare
b0249 ykfF +0.3 1.2 CP4-6 prophage; predicted protein (NCBI) compare
b1843 yobB +0.3 1.1 hypothetical protein (NCBI) compare
b3029 ygiN +0.3 1.1 quinol monooxygenase (NCBI) compare
b1035 ycdY +0.3 2.4 hypothetical protein (NCBI) compare
b1296 ycjJ +0.3 1.4 putative amino acid/amine transport protein (VIMSS) compare
b4215 ytfI +0.3 0.8 hypothetical protein (NCBI) compare
b0909 ycaL +0.3 1.6 putative heat shock protein (VIMSS) compare
b4345 mcrC +0.3 0.5 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI) compare
b1558 cspF +0.3 0.9 Qin prophage; cold shock protein (NCBI) compare
b2317 dedA +0.3 1.5 conserved inner membrane protein (NCBI) compare
b1572 ydfB +0.3 0.7 orf, hypothetical protein (VIMSS) compare
b0515 ylbA +0.3 2.6 hypothetical protein (NCBI) compare
b2706 gutM +0.3 1.5 DNA-binding transcriptional activator of glucitol operon (NCBI) compare
b4603 rseX +0.3 0.4 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1343 dbpA +0.3 1.8 ATP-dependent RNA helicase, specific for 23S rRNA (NCBI) compare
b4363 yjjB +0.3 1.9 conserved inner membrane protein (RefSeq) compare
b2603 yfiR +0.3 2.2 hypothetical protein (NCBI) compare
b1419 ydcA +0.3 1.1 hypothetical protein (NCBI) compare
b2809 b2809 +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b0790 ybhP +0.3 1.5 predicted DNase (NCBI) compare
b1462 b1462 +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b1127 pepT +0.3 2.0 peptidase T (NCBI) compare
b2002 yeeS +0.3 2.1 CP4-44 prophage; predicted DNA repair protein (NCBI) compare
b1299 puuR +0.3 1.8 DNA-binding transcriptional repressor (NCBI) compare
b2143 cdd +0.3 1.2 cytidine deaminase (NCBI) compare
b2334 yfcQ +0.3 2.0 predicted fimbrial-like adhesin protein (NCBI) compare
b3382 yhfY +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b1682 sufC +0.3 1.6 cysteine desulfurase ATPase component (NCBI) compare
b1320 ycjW +0.3 1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b2992 hybE +0.3 2.0 hydrogenase 2-specific chaperone (NCBI) compare
b0454 ybaZ +0.3 1.8 predicted methyltransferase (NCBI) compare
b3378 yhfU +0.3 1.4 orf, hypothetical protein (VIMSS) compare
b2959 yggL +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b4631 ykgQ +0.3 0.9 no description compare
b2378 ddg +0.3 1.3 putative heat shock protein (VIMSS) compare
b0267 yagA +0.3 2.2 CP4-6 prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b3909 kdgT +0.3 1.8 2-keto-3-deoxy-D-gluconate transport system (VIMSS) compare
b3646 yicG +0.3 2.0 orf, hypothetical protein (VIMSS) compare
b3098 yqjD +0.3 1.7 hypothetical protein (NCBI) compare
b1760 ynjH +0.3 1.4 hypothetical protein (NCBI) compare
b1743 spy +0.3 1.2 envelope stress induced periplasmic protein (NCBI) compare
b4360 yjjA +0.3 1.8 putative glycoprotein/receptor (VIMSS) compare
b0189 yaeO +0.3 1.5 orf, hypothetical protein (VIMSS) compare
b4030 yjbA +0.3 1.5 phosphate-starvation-inducible protein PsiE (NCBI) compare
b3208 mtgA +0.3 1.9 monofunctional biosynthetic peptidoglycan transglycosylase (NCBI) compare
b1412 azoR +0.3 1.4 acyl carrier protein phosphodiesterase (NCBI) compare
b1321 ycjX +0.3 1.6 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b3658 selC +0.3 0.9 tRNA-Sec (NCBI) compare
b0872 hcr +0.3 1.0 HCP oxidoreductase, NADH-dependent (NCBI) compare
b2717 hycI +0.3 2.2 protease involved in processing C-terminal end of HycE (NCBI) compare
b4565 sgcB +0.3 1.8 predicted enzyme IIB component of PTS (NCBI) compare
b1148 ymfM +0.3 1.0 e14 prophage; predicted protein (NCBI) compare
b2050 wcaI +0.3 1.2 predicted glycosyl transferase (NCBI) compare
b3002 yqhA +0.3 0.8 hypothetical protein (NCBI) compare
b0987 ymcD +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b1958 yedI +0.3 1.5 conserved inner membrane protein (NCBI) compare
b2922 yggE +0.3 1.9 hypothetical protein (NCBI) compare
b1450 b1450 +0.3 1.5 orf, hypothetical protein (VIMSS) compare
b1263 trpD +0.3 1.3 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b0775 bioB +0.3 1.4 biotin synthase (NCBI) compare
b1752 ydjZ +0.3 1.3 conserved inner membrane protein (NCBI) compare
b1833 yebS +0.3 1.5 conserved inner membrane protein (NCBI) compare
b1328 ycjZ +0.3 1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b4456 ryiA +0.3 1.8 regulatory sRNA (NCBI) compare
b0995 torR +0.3 1.3 DNA-binding response regulator in two-component regulatory system with TorS (NCBI) compare
b4057 yjbR +0.3 1.3 hypothetical protein (NCBI) compare
b1686 ydiI +0.3 0.5 hypothetical protein (NCBI) compare
b1057 yceJ +0.3 1.8 predicted cytochrome b561 (NCBI) compare
b4559 yjdO +0.3 1.2 hypothetical protein (NCBI) compare
b1349 recT +0.3 1.8 Rac prophage; recombination and repair protein (NCBI) compare
b0809 glnQ +0.3 1.2 glutamine ABC transporter ATP-binding protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in predation experiments

For predation HD100_bdellovibrio across organisms