| | gene | name | fitness | t score | description | |
|---|
| b4006 | purH | -3.5 | -16.0 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0142 | folK | -3.4 | -1.2 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b2499 | purM | -3.3 | -8.0 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b2312 | purF | -3.3 | -12.0 | amidophosphoribosyltransferase (NCBI) | compare |
| b2557 | purL | -3.3 | -15.9 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b0523 | purE | -3.3 | -8.3 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b1863 | ruvC | -3.1 | -3.0 | Holliday junction resolvase (NCBI) | compare |
| b4005 | purD | -3.1 | -13.5 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b1861 | ruvA | -2.8 | -1.9 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b2476 | purC | -2.6 | -3.4 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b3619 | rfaD | -2.4 | -6.2 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b2830 | nudH | -2.4 | -1.6 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b3052 | rfaE | -2.3 | -8.2 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b3621 | rfaC | -2.2 | -9.1 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b3642 | pyrE | -2.1 | -7.3 | orotate phosphoribosyltransferase (NCBI) | compare |
| b3261 | fis | -2.1 | -3.7 | DNA-binding protein Fis (NCBI) | compare |
| b0522 | purK | -2.1 | -10.9 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b4388 | serB | -2.1 | -10.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b3977 | tyrU | -2.0 | -1.4 | tRNA-Tyr (NCBI) | compare |
| b2784 | relA | -2.0 | -11.7 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b2913 | serA | -2.0 | -9.9 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b0033 | carB | -1.9 | -15.2 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b1281 | pyrF | -1.9 | -5.7 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b0032 | carA | -1.9 | -8.3 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b1062 | pyrC | -1.9 | -8.6 | dihydroorotase (NCBI) | compare |
| b0738 | tolR | -1.9 | -3.7 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b1291 | sapD | -1.9 | -2.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0889 | lrp | -1.8 | -3.3 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b0907 | serC | -1.8 | -6.5 | phosphoserine aminotransferase (NCBI) | compare |
| b4245 | pyrB | -1.8 | -10.1 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b0053 | surA | -1.8 | -6.8 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b2318 | truA | -1.7 | -4.0 | tRNA pseudouridine synthase A (NCBI) | compare |
| b1361 | ydaW | -1.6 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b0945 | pyrD | -1.6 | -9.9 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0739 | tolA | -1.6 | -3.7 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b3613 | yibP | -1.6 | -5.0 | putative membrane protein (VIMSS) | compare |
| b1290 | sapF | -1.5 | -2.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0222 | lpcA | -1.5 | -2.4 | phosphoheptose isomerase (NCBI) | compare |
| b2168 | fruK | -1.5 | -1.4 | 1-phosphofructokinase (NCBI) | compare |
| b1176 | minC | -1.4 | -4.2 | septum formation inhibitor (NCBI) | compare |
| b0688 | pgm | -1.4 | -3.2 | phosphoglucomutase (NCBI) | compare |
| b3620 | rfaF | -1.4 | -5.2 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b1865 | nudB | -1.4 | -1.4 | dATP pyrophosphohydrolase (NCBI) | compare |
| b2501 | ppk | -1.4 | -7.7 | polyphosphate kinase (NCBI) | compare |
| b3863 | polA | -1.4 | -1.5 | DNA polymerase I (NCBI) | compare |
| b0145 | dksA | -1.3 | -3.5 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0049 | apaH | -1.3 | -2.8 | diadenosinetetraphosphatase (NCBI) | compare |
| b4171 | miaA | -1.3 | -3.8 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b3790 | rffC | -1.3 | -6.1 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b3916 | pfkA | -1.3 | -3.5 | 6-phosphofructokinase (NCBI) | compare |
| b4676 | yoaK | -1.3 | -0.9 | expressed protein (RefSeq) | compare |
| b4699 | fnrS | -1.2 | -1.3 | FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) | compare |
| b0439 | lon | -1.2 | -4.0 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b3839 | tatC | -1.2 | -5.8 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0401 | brnQ | -1.2 | -8.3 | predicted branched chain amino acid transporter (LIV-II) (NCBI) | compare |
| b3741 | gidA | -1.2 | -4.3 | glucose-inhibited division protein A (NCBI) | compare |
| b2912 | ygfA | -1.2 | -3.1 | putative ligase (VIMSS) | compare |
| b3026 | qseC | -1.1 | -3.9 | sensory histidine kinase in two-component regulatory system with QseB (NCBI) | compare |
| b4246 | pyrL | -1.1 | -2.6 | pyrBI operon leader peptide (NCBI) | compare |
| b2313 | cvpA | -1.1 | -2.0 | membrane protein required for colicin V production (NCBI) | compare |
| b4552 | yrhC | -1.1 | -1.1 | no description | compare |
| b0683 | fur | -1.1 | -1.0 | ferric uptake regulator (NCBI) | compare |
| b3786 | rffE | -1.1 | -8.7 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b3387 | dam | -1.0 | -8.1 | DNA adenine methylase (NCBI) | compare |
| b3838 | tatB | -1.0 | -4.8 | sec-independent translocase (NCBI) | compare |
| b4155 | yjeA | -1.0 | -0.6 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b1712 | ihfA | -1.0 | -1.8 | integration host factor subunit alpha (NCBI) | compare |
| b0737 | tolQ | -1.0 | -1.6 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3791 | rffA | -0.9 | -5.8 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b3631 | rfaG | -0.9 | -7.8 | glucosyltransferase I (NCBI) | compare |
| b0890 | ftsK | -0.9 | -2.8 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b3794 | rffM | -0.9 | -5.7 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b1293 | sapB | -0.9 | -1.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0949 | uup | -0.9 | -5.8 | fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) | compare |
| b2350 | yfdG | -0.9 | -4.7 | CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) | compare |
| b3609 | secB | -0.9 | -3.5 | export protein SecB (NCBI) | compare |
| b3787 | rffD | -0.9 | -6.6 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b1642 | slyA | -0.9 | -1.4 | transcriptional regulator for cryptic hemolysin (VIMSS) | compare |
| b2188 | yejM | -0.8 | -5.6 | predicted hydrolase, inner membrane (NCBI) | compare |
| b1103 | ycfF | -0.8 | -1.6 | orf, hypothetical protein (VIMSS) | compare |
| b1524 | yneH | -0.8 | -0.9 | predicted glutaminase (NCBI) | compare |
| b1175 | minD | -0.8 | -4.0 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b2330 | yfcB | -0.8 | -1.3 | putative adenine-specific methylase (VIMSS) | compare |
| b0741 | pal | -0.8 | -2.3 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b3405 | ompR | -0.8 | -3.1 | osmolarity response regulator (NCBI) | compare |
| b3792 | wzxE | -0.8 | -4.9 | O-antigen translocase (NCBI) | compare |
| b3198 | kdsC | -0.8 | -2.1 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) | compare |
| b1506 | yneL | -0.8 | -1.1 | predicted transcriptional regulator (NCBI) | compare |
| b4215 | ytfI | -0.8 | -1.6 | hypothetical protein (NCBI) | compare |
| b2329 | aroC | -0.8 | -3.0 | chorismate synthase (NCBI) | compare |
| b1686 | ydiI | -0.8 | -1.9 | hypothetical protein (NCBI) | compare |
| b3778 | rep | -0.7 | -4.0 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b0014 | dnaK | -0.7 | -1.2 | molecular chaperone DnaK (NCBI) | compare |
| b2699 | recA | -0.7 | -1.1 | recombinase A (NCBI) | compare |
| b3842 | rfaH | -0.7 | -3.7 | transcriptional activator RfaH (NCBI) | compare |
| b0357 | yaiN | -0.7 | -1.6 | putative alpha helix chain (VIMSS) | compare |
| b4585 | sroB | -0.7 | -1.2 | Novel sRNA, function unknown (RefSeq) | compare |
| b2175 | spr | -0.7 | -2.9 | predicted peptidase, outer membrane lipoprotein (NCBI) | compare |
| b2569 | lepA | -0.7 | -2.7 | GTP-binding protein LepA (NCBI) | compare |
| b1257 | yciE | -0.7 | -0.4 | hypothetical protein (NCBI) | compare |
| b4431 | rprA | -0.7 | -1.8 | Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) | compare |
| b4481 | rffT | -0.7 | -3.6 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b2698 | recX | -0.7 | -1.7 | RecA regulator RecX (NCBI) | compare |
| b4239 | treC | -0.7 | -1.7 | trehalose-6-P hydrolase (NCBI) | compare |
| b3630 | rfaP | -0.7 | -5.1 | kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) | compare |
| b1344 | ydaO | -0.7 | -2.1 | predicted C32 tRNA thiolase (NCBI) | compare |
| b4642 | yoeD | -0.7 | -1.5 | no description | compare |
| b2259 | pmrD | -0.7 | -1.0 | polymyxin resistance protein B (VIMSS) | compare |
| b1540 | ydfH | -0.6 | -1.1 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0218 | yafU | -0.6 | -1.9 | predicted inner membrane protein (RefSeq) | compare |
| b0588 | fepC | -0.6 | -4.3 | iron-enterobactin transporter subunit (NCBI) | compare |
| b1567 | intK | -0.6 | -1.0 | Qin prophage; predicted protein (RefSeq) | compare |
| b3389 | aroB | -0.6 | -4.7 | 3-dehydroquinate synthase (NCBI) | compare |
| b1363 | trkG | -0.6 | -0.4 | Rac prophage; potassium transporter subunit (NCBI) | compare |
| b1160 | elbA | -0.6 | -1.0 | hypothetical protein (NCBI) | compare |
| b3784 | rfe | -0.6 | -5.2 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b1850 | eda | -0.6 | -2.1 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b1984 | asnW | -0.6 | -0.8 | tRNA-Asn (NCBI) | compare |
| b1286 | rnb | -0.6 | -1.6 | exoribonuclease II (NCBI) | compare |
| b4513 | kdpF | -0.6 | -1.2 | potassium ion accessory transporter subunit (NCBI) | compare |
| b4593 | ymgI | -0.6 | -0.7 | hypothetical protein (RefSeq) | compare |
| b4653 | yicT | -0.6 | -0.9 | no description | compare |
| b0632 | dacA | -0.6 | -3.8 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) | compare |
| b3169 | nusA | -0.6 | -2.0 | transcription elongation factor NusA (NCBI) | compare |
| b1075 | flgD | -0.6 | -1.9 | flagellar basal body rod modification protein D (NCBI) | compare |
| b1563 | relE | -0.6 | -1.6 | Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) | compare |
| b3979 | thrT | -0.6 | -0.3 | tRNA-Thr (NCBI) | compare |
| b4179 | vacB | -0.6 | -3.2 | putative enzyme (VIMSS) | compare |
| b0585 | fes | -0.6 | -2.9 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b1351 | racC | -0.6 | -0.5 | Rac prophage; predicted protein (NCBI) | compare |
| b4203 | rplI | -0.6 | -2.8 | 50S ribosomal protein L9 (NCBI) | compare |
| b4177 | purA | -0.6 | -0.4 | adenylosuccinate synthetase (NCBI) | compare |
| b2215 | ompC | -0.6 | -3.2 | outer membrane porin protein C (NCBI) | compare |
| b1977 | asnT | -0.6 | -1.1 | tRNA-Asn (NCBI) | compare |
| b1589 | ynfG | -0.6 | -2.5 | oxidoreductase, Fe-S subunit (NCBI) | compare |
| b1192 | ldcA | -0.6 | -1.7 | L,D-carboxypeptidase A (NCBI) | compare |
| b2293 | yfbT | -0.6 | -2.1 | putative phosphatase (VIMSS) | compare |
| b1129 | phoQ | -0.6 | -1.4 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b0908 | aroA | -0.6 | -3.3 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b0590 | fepD | -0.6 | -3.4 | iron-enterobactin transporter subunit (NCBI) | compare |
| b1084 | rne | -0.6 | -2.4 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b3761 | trpT | -0.6 | -1.2 | tRNA-Trp (NCBI) | compare |
| b4025 | pgi | -0.6 | -3.8 | glucose-6-phosphate isomerase (NCBI) | compare |
| b3649 | rpoZ | -0.6 | -2.5 | DNA-directed RNA polymerase subunit omega (NCBI) | compare |
| b1426 | ydcH | -0.6 | -1.0 | orf, hypothetical protein (VIMSS) | compare |
| b2742 | nlpD | -0.5 | -3.9 | predicted outer membrane lipoprotein (NCBI) | compare |
| b1452 | yncE | -0.5 | -3.0 | hypothetical protein (NCBI) | compare |
| b2518 | ndk | -0.5 | -1.6 | nucleoside diphosphate kinase (NCBI) | compare |
| b1627 | rsxA | -0.5 | -2.1 | Na(+)-translocating NADH-quinone reductase subunit E (NCBI) | compare |
| b3199 | yrbK | -0.5 | -1.6 | hypothetical protein (NCBI) | compare |
| b3627 | rfaI | -0.5 | -3.9 | UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) | compare |
| b1684 | sufA | -0.5 | -1.2 | iron-sulfur cluster assembly scaffold protein (NCBI) | compare |
| b3706 | trmE | -0.5 | -2.1 | tRNA modification GTPase (NCBI) | compare |
| b1358 | ydaT | -0.5 | -0.8 | Rac prophage; predicted protein (NCBI) | compare |
| b4045 | yjbJ | -0.5 | -1.4 | predicted stress response protein (NCBI) | compare |
| b2125 | yehT | -0.5 | -2.4 | orf, hypothetical protein (VIMSS) | compare |
| b2951 | yggS | -0.5 | -2.6 | predicted enzyme (NCBI) | compare |
| b4451 | ryhB | -0.5 | -1.3 | Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) | compare |
| b1151 | ymfO | -0.5 | -1.3 | e14 prophage; conserved protein (RefSeq) | compare |
| b3024 | ygiW | -0.5 | -1.8 | hypothetical protein (NCBI) | compare |
| b0535 | fimZ | -0.5 | -1.9 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1904 | yecR | -0.5 | -2.5 | hypothetical protein (NCBI) | compare |
| b4279 | yjhB | -0.5 | -0.3 | putative transport protein (VIMSS) | compare |
| b1025 | ycdT | -0.5 | -0.9 | predicted diguanylate cyclase (NCBI) | compare |
| b1855 | lpxM | -0.5 | -1.7 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b1183 | umuD | -0.5 | -1.0 | DNA polymerase V, subunit D (NCBI) | compare |
| b3281 | aroE | -0.5 | -4.2 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b0592 | fepB | -0.5 | -3.3 | iron-enterobactin transporter subunit (NCBI) | compare |
| b2279 | nuoK | -0.5 | -0.8 | NADH dehydrogenase subunit K (NCBI) | compare |
| b2516 | yfgA | -0.5 | -2.7 | hypothetical protein (NCBI) | compare |
| b1696 | ydiP | -0.5 | -1.2 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0740 | tolB | -0.5 | -1.4 | translocation protein TolB precursor (NCBI) | compare |
| b1476 | fdnI | -0.5 | -0.6 | formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) | compare |
| b1960 | vsr | -0.5 | -1.9 | DNA mismatch endonuclease of very short patch repair (NCBI) | compare |
| b2645 | yfjZ | -0.5 | -2.7 | CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) | compare |
| b3017 | sufI | -0.5 | -3.8 | repressor protein for FtsI (NCBI) | compare |
| b1480 | sra | -0.5 | -0.8 | 30S ribosomal subunit protein S22 (NCBI) | compare |
| b2517 | yfgB | -0.5 | -2.7 | predicted enzyme (NCBI) | compare |
| b0584 | fepA | -0.5 | -3.2 | iron-enterobactin outer membrane transporter (NCBI) | compare |
| b1438 | ydcQ | -0.5 | -1.1 | predicted DNA-binding transcriptional regulator (RefSeq) | compare |
| b4012 | yjaB | -0.4 | -1.3 | predicted acetyltransferase (NCBI) | compare |
| b0471 | ybaB | -0.4 | -1.4 | hypothetical protein (NCBI) | compare |
| b1251 | yciI | -0.4 | -1.6 | orf, hypothetical protein (VIMSS) | compare |
| b3404 | envZ | -0.4 | -3.3 | osmolarity sensor protein (NCBI) | compare |
| b0999 | cbpM | -0.4 | -1.7 | modulator of CbpA co-chaperone (NCBI) | compare |
| b2954 | yggV | -0.4 | -2.3 | putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) | compare |
| b1040 | csgD | -0.4 | -1.1 | DNA-binding transcriptional activator in two-component regulatory system (NCBI) | compare |
| b4506 | ykgO | -0.4 | -1.7 | rpmJ (L36) paralog (NCBI) | compare |
| b4104 | phnE | -0.4 | -1.1 | phosphonate/organophosphate ester transporter subunit (NCBI) | compare |
| b0379 | yaiY | -0.4 | -1.6 | predicted inner membrane protein (NCBI) | compare |
| b0015 | dnaJ | -0.4 | -3.3 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b2500 | purN | -0.4 | -2.2 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b3961 | oxyR | -0.4 | -3.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1551 | b1551 | -0.4 | -0.2 | orf, hypothetical protein (VIMSS) | compare |
| b1481 | b1481 | -0.4 | -2.3 | orf, hypothetical protein (VIMSS) | compare |
| b1976 | b1976 | -0.4 | -1.6 | orf, hypothetical protein (VIMSS) | compare |
| b2136 | yohD | -0.4 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b1989 | asnV | -0.4 | -1.4 | tRNA-Asn (NCBI) | compare |
| b3623 | rfaK | -0.4 | -1.4 | lipopolysaccharide core biosynthesis (NCBI) | compare |
| b1269 | rluB | -0.4 | -1.2 | 23S rRNA pseudouridylate synthase (NCBI) | compare |