Experiment set31IT030 for Escherichia coli BW25113

Compare to:

RCH2_defined_1percent_glucose with Sodium Chloride 200 mM and Betaine 100 uM

200 most important genes:

  gene name fitness t score description  
b2312 purF -5.8 -10.0 amidophosphoribosyltransferase (NCBI) compare
b2476 purC -5.2 -4.9 phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) compare
b2557 purL -5.0 -18.5 phosphoribosylformylglycinamidine synthase (NCBI) compare
b1062 pyrC -4.9 -13.5 dihydroorotase (NCBI) compare
b0522 purK -4.9 -14.2 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b1281 pyrF -4.9 -6.7 orotidine 5'-phosphate decarboxylase (NCBI) compare
b2499 purM -4.8 -8.3 phosphoribosylaminoimidazole synthetase (NCBI) compare
b3642 pyrE -4.6 -7.6 orotate phosphoribosyltransferase (NCBI) compare
b4005 purD -4.2 -12.3 phosphoribosylamine--glycine ligase (NCBI) compare
b4006 purH -4.1 -13.9 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b0019 nhaA -3.9 -13.2 pH-dependent sodium/proton antiporter (NCBI) compare
b0033 carB -3.8 -13.8 carbamoyl-phosphate synthase large subunit (NCBI) compare
b0523 purE -3.8 -4.1 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b0145 dksA -3.7 -7.5 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0945 pyrD -3.7 -13.5 dihydroorotate dehydrogenase (NCBI) compare
b4388 serB -3.4 -13.0 3-phosphoserine phosphatase (NCBI) compare
b2414 cysK -3.3 -16.9 cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) compare
b3870 glnA -3.3 -6.3 glutamine synthetase (NCBI) compare
b2913 serA -3.3 -12.6 D-3-phosphoglycerate dehydrogenase (NCBI) compare
b0142 folK -3.2 -1.1 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1693 aroD -3.2 -10.1 3-dehydroquinate dehydratase (NCBI) compare
b4245 pyrB -3.1 -11.7 aspartate carbamoyltransferase catalytic subunit (NCBI) compare
b0386 proC -2.9 -8.2 pyrroline-5-carboxylate reductase (NCBI) compare
b0564 appY -2.8 -1.1 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b0032 carA -2.8 -4.8 carbamoyl-phosphate synthase small subunit (NCBI) compare
b3281 aroE -2.8 -17.8 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1850 eda -2.7 -3.0 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3956 ppc -2.6 -18.6 phosphoenolpyruvate carboxylase (NCBI) compare
b0907 serC -2.6 -12.5 phosphoserine aminotransferase (NCBI) compare
b1506 yneL -2.6 -3.2 predicted transcriptional regulator (NCBI) compare
b0908 aroA -2.6 -10.8 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b3389 aroB -2.5 -12.6 3-dehydroquinate synthase (NCBI) compare
b2329 aroC -2.5 -6.7 chorismate synthase (NCBI) compare
b3916 pfkA -2.4 -5.3 6-phosphofructokinase (NCBI) compare
b0004 thrC -2.4 -10.2 threonine synthase (NCBI) compare
b2750 cysC -2.4 -9.1 adenylylsulfate kinase (NCBI) compare
b2479 gcvR -2.3 -8.8 transcriptional regulation of gcv operon (VIMSS) compare
b2762 cysH -2.2 -9.1 phosphoadenosine phosphosulfate reductase (NCBI) compare
b4214 cysQ -2.2 -14.1 PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) compare
b2318 truA -2.1 -5.9 tRNA pseudouridine synthase A (NCBI) compare
b2763 cysI -2.1 -10.5 sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) compare
b0243 proA -2.1 -11.1 gamma-glutamyl phosphate reductase (NCBI) compare
b2600 tyrA -2.0 -5.3 fused chorismate mutase T/prephenate dehydrogenase (NCBI) compare
b4155 yjeA -2.0 -1.9 putative lysyl-tRNA synthetase (VIMSS) compare
b3941 metF -2.0 -11.0 5,10-methylenetetrahydrofolate reductase (NCBI) compare
b2764 cysJ -1.9 -11.0 sulfite reductase, alpha subunit, flavoprotein (NCBI) compare
b3960 argH -1.9 -11.3 argininosuccinate lyase (NCBI) compare
b0242 proB -1.9 -5.2 gamma-glutamyl kinase (NCBI) compare
b4177 purA -1.9 -1.3 adenylosuccinate synthetase (NCBI) compare
b2894 xerD -1.9 -1.3 site-specific tyrosine recombinase XerD (NCBI) compare
b4647 mokA -1.9 -1.7 no description compare
b4529 ydbJ -1.9 -1.8 hypothetical protein (NCBI) compare
b4025 pgi -1.8 -8.3 glucose-6-phosphate isomerase (NCBI) compare
b0990 cspG -1.8 -1.7 DNA-binding transcriptional regulator (NCBI) compare
b3172 argG -1.8 -10.6 argininosuccinate synthase (NCBI) compare
b0003 thrB -1.7 -9.1 homoserine kinase (NCBI) compare
b3008 metC -1.7 -9.5 cystathionine beta-lyase (NCBI) compare
b2313 cvpA -1.7 -2.9 membrane protein required for colicin V production (NCBI) compare
b4676 yoaK -1.7 -0.8 expressed protein (RefSeq) compare
b0113 pdhR -1.7 -6.3 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b2518 ndk -1.7 -3.7 nucleoside diphosphate kinase (NCBI) compare
b3939 metB -1.7 -9.1 cystathionine gamma-synthase (NCBI) compare
b2023 hisH -1.6 -6.7 imidazole glycerol phosphate synthase subunit HisH (NCBI) compare
b3781 trxA -1.6 -4.7 thioredoxin 1 (VIMSS) compare
b3770 ilvE -1.5 -10.5 branched-chain amino acid aminotransferase (NCBI) compare
b1358 ydaT -1.5 -1.4 Rac prophage; predicted protein (NCBI) compare
b3771 ilvD -1.5 -11.1 dihydroxy-acid dehydratase (NCBI) compare
b2699 recA -1.5 -2.1 recombinase A (NCBI) compare
b0696 kdpC -1.5 -3.6 potassium-transporting ATPase subunit C (NCBI) compare
b3774 ilvC -1.5 -10.6 ketol-acid reductoisomerase (NCBI) compare
b0002 thrA -1.5 -9.8 bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) compare
b2500 purN -1.4 -4.6 phosphoribosylglycinamide formyltransferase (NCBI) compare
b2168 fruK -1.4 -2.2 1-phosphofructokinase (NCBI) compare
b3368 cysG -1.4 -11.2 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) compare
b2601 aroF -1.4 -7.1 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible (NCBI) compare
b4013 metA -1.4 -5.7 homoserine O-succinyltransferase (NCBI) compare
b0890 ftsK -1.3 -5.8 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0589 fepG -1.3 -8.5 iron-enterobactin transporter subunit (NCBI) compare
b2020 hisD -1.3 -7.6 histidinol dehydrogenase (NCBI) compare
b3957 argE -1.3 -9.4 acetylornithine deacetylase (NCBI) compare
b3958 argC -1.3 -9.6 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
b2026 hisI -1.3 -6.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) compare
b1261 trpB -1.3 -4.5 tryptophan synthase subunit beta (NCBI) compare
b2818 argA -1.3 -7.5 N-acetylglutamate synthase (NCBI) compare
b1260 trpA -1.3 -4.7 tryptophan synthase subunit alpha (NCBI) compare
b2025 hisF -1.3 -4.6 imidazole glycerol phosphate synthase subunit HisF (NCBI) compare
b1502 ydeQ -1.3 -3.0 predicted fimbrial-like adhesin protein (NCBI) compare
b4443 gcvB -1.3 -0.7 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b0588 fepC -1.2 -6.8 iron-enterobactin transporter subunit (NCBI) compare
b0889 lrp -1.2 -2.6 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b1332 ynaJ -1.2 -0.9 predicted inner membrane protein (NCBI) compare
b2846 yqeH -1.2 -0.7 orf, hypothetical protein (VIMSS) compare
b3959 argB -1.2 -7.3 acetylglutamate kinase (RefSeq) compare
b1217 chaB -1.2 -1.8 cation transport regulator (NCBI) compare
b2024 hisA -1.2 -3.2 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b2019 hisG -1.2 -4.6 ATP phosphoribosyltransferase (NCBI) compare
b2022 hisB -1.2 -5.6 imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) compare
b3390 aroK -1.2 -1.5 shikimate kinase I (NCBI) compare
b0592 fepB -1.1 -6.6 iron-enterobactin transporter subunit (NCBI) compare
b0590 fepD -1.1 -6.5 iron-enterobactin transporter subunit (NCBI) compare
b2599 pheA -1.1 -5.8 fused chorismate mutase P/prephenate dehydratase (NCBI) compare
b3237 argR -1.1 -4.8 arginine repressor (NCBI) compare
b1232 purU -1.1 -6.3 formyltetrahydrofolate deformylase (NCBI) compare
b4570 lomR -1.1 -2.3 no description compare
b1231 tyrT -1.1 -1.1 tRNA-Tyr (NCBI) compare
b3465 yhhF -1.1 -6.4 predicted methyltransferase (NCBI) compare
b1709 btuD -1.1 -1.1 vitamin B12-transporter ATPase (NCBI) compare
b1863 ruvC -1.1 -1.9 Holliday junction resolvase (NCBI) compare
b1505 ydeT -1.0 -1.1 hypothetical protein (RefSeq) compare
b0437 clpP -1.0 -5.1 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0232 yafN -1.0 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b4066 yjcF -1.0 -0.7 hypothetical protein (NCBI) compare
b4048 yjbM -1.0 -1.3 hypothetical protein (NCBI) compare
b1258 yciF -1.0 -1.1 hypothetical protein (NCBI) compare
b1171 b1171 -1.0 -1.8 orf, hypothetical protein (VIMSS) compare
b4513 kdpF -1.0 -2.6 potassium ion accessory transporter subunit (NCBI) compare
b3649 rpoZ -1.0 -3.6 DNA-directed RNA polymerase subunit omega (NCBI) compare
b0200 gmhB -1.0 -1.8 hypothetical protein (NCBI) compare
b1499 ydeO -1.0 -0.6 predicted DNA-binding transcriptional acfivator (NCBI) compare
b3398 yrfF -1.0 -2.9 predicted inner membrane protein (NCBI) compare
b1765 ydjA -1.0 -1.0 predicted oxidoreductase (NCBI) compare
b3726 pstA -1.0 -3.5 phosphate transporter subunit (NCBI) compare
b0114 aceE -0.9 -1.7 pyruvate dehydrogenase subunit E1 (NCBI) compare
b3204 ptsN -0.9 -3.8 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2501 ppk -0.9 -6.0 polyphosphate kinase (NCBI) compare
b0071 leuD -0.9 -4.8 isopropylmalate isomerase small subunit (NCBI) compare
b4480 hdfR -0.9 -5.2 transcriptional regulator HdfR (NCBI) compare
b1551 b1551 -0.9 -0.5 orf, hypothetical protein (VIMSS) compare
b0073 leuB -0.9 -6.1 3-isopropylmalate dehydrogenase (VIMSS) compare
b3772 ilvA -0.9 -6.8 threonine dehydratase (NCBI) compare
b1857 yebL -0.9 -4.7 putative adhesin (VIMSS) compare
b3725 pstB -0.9 -0.8 phosphate transporter subunit (NCBI) compare
b0088 murD -0.9 -2.2 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b3623 rfaK -0.9 -2.1 lipopolysaccharide core biosynthesis (NCBI) compare
b2055 wcaE -0.9 -0.6 predicted glycosyl transferase (NCBI) compare
b3213 gltD -0.9 -6.0 glutamate synthase, 4Fe-4S protein, small subunit (NCBI) compare
b1101 ptsG -0.9 -6.3 fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) compare
b0697 kdpB -0.9 -5.1 potassium-transporting ATPase subunit B (NCBI) compare
b1286 rnb -0.9 -2.0 exoribonuclease II (NCBI) compare
b1262 trpC -0.9 -3.2 N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) compare
b3212 gltB -0.9 -7.5 glutamate synthase, large subunit (NCBI) compare
b1058 yceO -0.9 -0.4 hypothetical protein (NCBI) compare
b1877 yecT -0.8 -2.8 orf, hypothetical protein (VIMSS) compare
b0698 kdpA -0.8 -5.2 potassium-transporting ATPase subunit A (NCBI) compare
b1576 ydfD -0.8 -0.5 Qin prophage; predicted protein (NCBI) compare
b1351 racC -0.8 -0.8 Rac prophage; predicted protein (NCBI) compare
b2822 recC -0.8 -3.5 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4631 ykgQ -0.8 -1.8 no description compare
b2021 hisC -0.8 -5.3 histidinol-phosphate aminotransferase (NCBI) compare
b1263 trpD -0.8 -2.1 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b2784 relA -0.8 -6.0 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0767 ybhE -0.8 -2.9 6-phosphogluconolactonase (NCBI) compare
b2340 sixA -0.8 -2.7 phosphohistidine phosphatase (NCBI) compare
b3773 ilvY -0.8 -4.8 DNA-binding transcriptional dual regulator (NCBI) compare
b0685 ybfE -0.8 -1.4 orf, hypothetical protein (VIMSS) compare
b2652 ileY -0.8 -0.7 tRNA-Ile (NCBI) compare
b4431 rprA -0.8 -2.3 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b0072 leuC -0.8 -5.9 isopropylmalate isomerase large subunit (NCBI) compare
b1182 hlyE -0.8 -0.5 hemolysin E (VIMSS) compare
b1573 ydfC -0.8 -1.6 Qin prophage; predicted protein (RefSeq) compare
b0438 clpX -0.8 -4.3 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0074 leuA -0.8 -5.5 2-isopropylmalate synthase (NCBI) compare
b1279 yciS -0.8 -1.0 conserved inner membrane protein (NCBI) compare
b0439 lon -0.8 -3.7 DNA-binding ATP-dependent protease La (NCBI) compare
b0535 fimZ -0.8 -3.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b3811 xerC -0.8 -1.6 site-specific tyrosine recombinase XerC (NCBI) compare
b2444 yffM -0.7 -1.7 CPZ-55 prophage; predicted protein (NCBI) compare
b2752 cysD -0.7 -3.8 sulfate adenylyltransferase subunit 2 (NCBI) compare
b0740 tolB -0.7 -2.7 translocation protein TolB precursor (NCBI) compare
b0077 ilvI -0.7 -5.1 acetolactate synthase III large subunit (NCBI) compare
b1363 trkG -0.7 -0.7 Rac prophage; potassium transporter subunit (NCBI) compare
b0880 cspD -0.7 -1.8 cold shock protein homolog (NCBI) compare
b3613 yibP -0.7 -3.0 putative membrane protein (VIMSS) compare
b2293 yfbT -0.7 -2.8 putative phosphatase (VIMSS) compare
b3341 rpsG -0.7 -1.0 30S ribosomal protein S7 (NCBI) compare
b1108 ycfP -0.7 -1.0 orf, hypothetical protein (VIMSS) compare
b1497 b1497 -0.7 -0.3 putative enzyme (VIMSS) compare
b1545 pinQ -0.7 -0.2 Qin prophage; predicted site-specific recombinase (NCBI) compare
b3155 yhbQ -0.7 -2.3 hypothetical protein (NCBI) compare
b0720 gltA -0.7 -2.9 citrate synthase (NCBI) compare
b3868 glnG -0.7 -3.2 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b2774 ygcW -0.7 -2.9 putative oxidoreductase (VIMSS) compare
b1690 ydiM -0.7 -2.3 predicted transporter (NCBI) compare
b2751 cysN -0.7 -3.0 sulfate adenylyltransferase subunit 1 (NCBI) compare
b0683 fur -0.7 -1.4 ferric uptake regulator (NCBI) compare
b4234 yjgA -0.7 -1.7 hypothetical protein (NCBI) compare
b3021 ygiT -0.7 -1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0695 kdpD -0.7 -4.6 fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein (NCBI) compare
b1773 ydjI -0.7 -1.7 predicted aldolase (NCBI) compare
b2029 gnd -0.7 -3.9 6-phosphogluconate dehydrogenase (NCBI) compare
b3741 gidA -0.7 -3.3 glucose-inhibited division protein A (NCBI) compare
b0078 ilvH -0.7 -4.0 acetolactate synthase small subunit (NCBI) compare
b4596 yciZ -0.6 -1.4 hypothetical protein (RefSeq) compare
b3728 pstS -0.6 -2.2 phosphate transporter subunit (NCBI) compare
b1347 ydaC -0.6 -0.3 Rac prophage; predicted protein (NCBI) compare
b4535 yniD -0.6 -1.0 predicted protein (RefSeq) compare
b0694 kdpE -0.6 -3.6 DNA-binding response regulator in two-component regulatory system with KdpD (NCBI) compare
b0331 prpB -0.6 -3.3 2-methylisocitrate lyase (NCBI) compare
b1493 gadB -0.6 -0.7 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1429 tehA -0.6 -0.8 potassium-tellurite ethidium and proflavin transporter (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in stress experiments

For stress Sodium Chloride across organisms