Experiment set2S763 for Escherichia coli ECRC62

Compare to:

Casamino-acids

200 most important genes:

  gene name fitness t score description  
BNILDI_06065 purH -6.3 -17.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
BNILDI_12215 guaA -5.7 -3.2 glutamine-hydrolyzing GMP synthase compare
BNILDI_08770 aceF -5.4 -1.9 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase compare
BNILDI_21485 pgm -5.3 -3.8 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) compare
BNILDI_21310 sucA -5.2 -4.7 2-oxoglutarate dehydrogenase E1 component compare
BNILDI_11945 purL -5.1 -16.8 phosphoribosylformylglycinamidine synthase compare
BNILDI_01630 nusA -5.0 -2.1 Transcription termination/antitermination protein NusA compare
BNILDI_12265 purN -5.0 -9.2 phosphoribosylglycinamide formyltransferase compare
BNILDI_18365 pyrF -4.9 -6.5 orotidine-5'-phosphate decarboxylase compare
BNILDI_21775 lipB -4.9 -0.9 lipoyl(octanoyl) transferase LipB compare
BNILDI_06995 purA -4.9 -2.6 adenylosuccinate synthase compare
BNILDI_07310 fbp -4.6 -12.4 class 1 fructose-bisphosphatase compare
BNILDI_20015 pyrD -4.6 -6.1 quinone-dependent dihydroorotate dehydrogenase compare
BNILDI_08910 panD -4.6 -4.0 aspartate 1-decarboxylase compare
BNILDI_19420 pyrC -4.6 -7.7 dihydroorotase compare
BNILDI_06060 purD -4.5 -9.2 Phosphoribosylamine--glycine ligase compare
BNILDI_12210 guaB -4.5 -6.0 IMP dehydrogenase compare
BNILDI_13415 nuoI -4.2 -1.8 NADH-quinone oxidoreductase subunit NuoI compare
BNILDI_13395 nuoE -4.1 -1.0 NADH-quinone oxidoreductase subunit NuoE compare
BNILDI_05830 sthA -4.1 -3.2 Si-specific NAD(P)(+) transhydrogenase compare
BNILDI_12270 purM -4.0 -5.9 Phosphoribosylformylglycinamidine cyclo-ligase compare
BNILDI_22260 purK -4.0 -7.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BNILDI_21295 sucD -3.9 -7.0 succinate--CoA ligase subunit alpha compare
BNILDI_12400 purC -3.9 -5.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BNILDI_13255 purF -3.9 -9.9 amidophosphoribosyltransferase compare
BNILDI_10365 rppH -3.8 -0.9 RNA pyrophosphohydrolase compare
BNILDI_03535 -3.8 -0.9 hypothetical protein compare
BNILDI_22255 purE -3.7 -2.5 N5-carboxyaminoimidazole ribonucleotide mutase compare
BNILDI_00095 ecpR -3.7 -0.9 ECP biosynthesis operon DNA-binding transcriptional regulator EcpR compare
BNILDI_22670 lon_P403L -3.6 -4.6 Lon protease compare
BNILDI_04035 pyrE -3.5 -6.3 Orotate phosphoribosyltransferase compare
BNILDI_11985 glyA -3.5 -2.3 serine hydroxymethyltransferase compare
BNILDI_22680 clpX -3.3 -4.0 ATP-dependent protease ATP-binding subunit ClpX compare
BNILDI_08765 aceE -3.2 -5.6 pyruvate dehydrogenase (acetyl-transferring), homodimeric type compare
BNILDI_13215 pdxB -3.2 -7.2 4-phosphoerythronate dehydrogenase PdxB compare
BNILDI_18870 ldcA -3.1 -4.2 muramoyltetrapeptide carboxypeptidase compare
BNILDI_13390 nuoC -3.0 -6.5 NADH-quinone oxidoreductase subunit C/D compare
BNILDI_21185 nadA -2.9 -5.2 quinolinate synthase NadA compare
BNILDI_20305 serC -2.9 -6.7 3-phosphoserine/phosphohydroxythreonine transaminase compare
BNILDI_13440 nuoN -2.9 -6.1 NADH-quinone oxidoreductase subunit NuoN compare
BNILDI_08430 pdxA -2.8 -6.4 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BNILDI_15415 yecV -2.8 -1.1 Protein YecV compare
BNILDI_08325 carA -2.8 -3.7 carbamoyl phosphate synthase small subunit compare
BNILDI_12105 hscB -2.7 -1.1 co-chaperone HscB compare
BNILDI_01400 prlF -2.7 -3.0 type II toxin-antitoxin system antitoxin PrlF compare
BNILDI_03970 waaO -2.5 -4.0 lipopolysaccharide 3-alpha-galactosyltransferase compare
BNILDI_00210 -2.5 -0.8 hypothetical protein compare
BNILDI_06875 -2.5 -0.8 Fumarate reductase subunit C compare
BNILDI_07385 pyrB -2.5 -6.6 aspartate carbamoyltransferase compare
BNILDI_21320 sdhA -2.5 -7.2 succinate dehydrogenase flavoprotein subunit compare
BNILDI_05170 trkH -2.4 -4.7 Trk system potassium transporter TrkH compare
BNILDI_21325 sdhD -2.4 -4.6 succinate dehydrogenase membrane anchor subunit compare
BNILDI_13385 nuoB -2.4 -3.0 NADH-quinone oxidoreductase subunit NuoB compare
BNILDI_13250 cvpA -2.4 -3.2 colicin V production protein compare
BNILDI_12290 arsC -2.3 -1.4 arsenate reductase (glutaredoxin) compare
BNILDI_13400 nuoF -2.3 -4.4 NADH-quinone oxidoreductase subunit NuoF compare
BNILDI_08785 acnB -2.3 -2.5 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
BNILDI_10010 sdhE -2.3 -1.3 FAD assembly factor SdhE compare
BNILDI_08415 apaH -2.3 -3.6 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
BNILDI_13420 nuoJ -2.3 -3.3 NADH-quinone oxidoreductase subunit J compare
BNILDI_09960 ubiI -2.3 -2.9 FAD-dependent 2-octaprenylphenol hydroxylase compare
BNILDI_06795 aspA -2.2 -7.6 aspartate ammonia-lyase compare
BNILDI_18470 trpD -2.2 -8.0 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
BNILDI_13430 nuoL -2.2 -3.6 NADH-quinone oxidoreductase subunit L compare
BNILDI_13380 nuoA -2.2 -3.2 NADH-quinone oxidoreductase subunit NuoA compare
BNILDI_03980 rfaG -2.2 -3.7 Lipopolysaccharide core biosynthesis protein RfaG compare
BNILDI_18760 prmC -2.1 -3.2 peptide chain release factor N(5)-glutamine methyltransferase compare
BNILDI_13410 nuoH -2.1 -3.1 NADH-quinone oxidoreductase subunit NuoH compare
BNILDI_04945 cyaA -2.1 -5.6 class I adenylate cyclase compare
BNILDI_08925 panB -2.1 -4.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
BNILDI_08330 carB -2.1 -7.6 carbamoyl-phosphate synthase large subunit compare
BNILDI_21315 sdhB -2.1 -1.8 succinate dehydrogenase iron-sulfur subunit SdhB compare
BNILDI_18480 trpA -2.1 -7.2 tryptophan synthase subunit alpha compare
BNILDI_21300 sucC -2.1 -2.5 ADP-forming succinate--CoA ligase subunit beta compare
BNILDI_13405 nuoG -2.0 -4.2 NADH-quinone oxidoreductase subunit NuoG compare
BNILDI_08580 cra -2.0 -3.3 catabolite repressor/activator compare
BNILDI_09730 rsmE -2.0 -1.0 16S rRNA (uracil(1498)-N(3))-methyltransferase compare
BNILDI_21235 tolB -1.9 -4.0 Tol-Pal system protein TolB compare
BNILDI_02975 panM -1.9 -2.7 aspartate 1-decarboxylase autocleavage activator PanM compare
BNILDI_13435 nuoM -1.9 -3.0 NADH-quinone oxidoreductase subunit M compare
BNILDI_05125 tatC -1.9 -5.2 Sec-independent protein translocase subunit TatC compare
BNILDI_17095 ynfA -1.8 -1.5 YnfA family protein compare
BNILDI_05145 fre -1.8 -4.1 NAD(P)H-flavin reductase compare
BNILDI_11275 yqaE -1.8 -2.2 UPF0057 membrane protein YqaE compare
BNILDI_02165 aroE -1.8 -3.4 shikimate dehydrogenase compare
BNILDI_15505 -1.8 -2.6 YebB family permuted papain-like enzyme compare
BNILDI_08735 nadC -1.8 -3.0 carboxylating nicotinate-nucleotide diphosphorylase compare
BNILDI_18475 trpB -1.7 -8.1 tryptophan synthase subunit beta compare
BNILDI_09945 ygfB -1.7 -3.2 UPF0149 family protein YgfB compare
BNILDI_18465 -1.7 -7.0 hypothetical protein compare
BNILDI_04555 atpC -1.7 -1.8 F0F1 ATP synthase subunit epsilon compare
BNILDI_19070 hflD -1.7 -1.8 high frequency lysogenization protein HflD compare
BNILDI_01940 mdh -1.7 -3.3 malate dehydrogenase compare
BNILDI_18575 -1.7 -0.8 hypothetical protein compare
BNILDI_10415 recB -1.6 -1.1 exodeoxyribonuclease V subunit beta compare
BNILDI_02615 aroB -1.6 -5.0 3-dehydroquinate synthase compare
BNILDI_15150 yedF -1.6 -0.7 sulfurtransferase-like selenium metabolism protein YedF compare
BNILDI_22685 clpP -1.6 -3.3 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
BNILDI_13220 usg -1.6 -1.3 aspartate-semialdehyde dehydrogenase compare
BNILDI_07675 fimC -1.6 -2.0 type 1 fimbria chaperone FimC compare
BNILDI_10045 lysS -1.6 -1.7 lysine--tRNA ligase compare
BNILDI_01555 ubiU -1.6 -1.5 Ubiquinone biosynthesis protein UbiU compare
BNILDI_06835 epmB -1.6 -1.7 EF-P beta-lysylation protein EpmB compare
BNILDI_02740 -1.6 -2.7 NfuA family Fe-S biogenesis protein compare
BNILDI_00265 gpt -1.5 -0.9 xanthine phosphoribosyltransferase compare
BNILDI_08920 panC -1.5 -4.0 pantoate--beta-alanine ligase compare
BNILDI_21245 tolR -1.5 -1.2 colicin uptake protein TolR compare
BNILDI_18295 sapA -1.5 -2.4 peptide ABC transporter substrate-binding protein SapA compare
BNILDI_18620 rssB -1.5 -2.7 two-component system response regulator RssB compare
BNILDI_20850 glnQ -1.5 -1.0 glutamine ABC transporter ATP-binding protein GlnQ compare
BNILDI_15485 nudB -1.5 -2.0 dihydroneopterin triphosphate diphosphatase compare
BNILDI_20300 aroA -1.5 -6.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
BNILDI_21040 bioB -1.5 -2.8 biotin synthase BioB compare
BNILDI_05720 metL -1.5 -6.6 bifunctional aspartate kinase/homoserine dehydrogenase II compare
BNILDI_16445 aroH -1.5 -4.6 3-deoxy-7-phosphoheptulonate synthase AroH compare
BNILDI_19545 cgsF -1.5 -1.1 curli production assembly/transport protein CsgF compare
BNILDI_20195 aspC -1.5 -5.3 aspartate transaminase compare
BNILDI_03975 rfaP -1.5 -1.3 lipopolysaccharide core heptose(I) kinase RfaP compare
BNILDI_07595 -1.4 -1.2 hypothetical protein compare
BNILDI_21330 sdhC -1.4 -0.7 succinate dehydrogenase cytochrome b556 subunit compare
BNILDI_18970 minE -1.4 -1.2 cell division topological specificity factor MinE compare
BNILDI_08980 dksA -1.4 -3.6 RNA polymerase-binding protein DksA compare
BNILDI_19310 rne -1.4 -1.4 ribonuclease E compare
BNILDI_20395 ftsK -1.3 -3.2 DNA translocase FtsK compare
BNILDI_15440 torY -1.3 -2.8 Cytochrome c-type protein TorY compare
BNILDI_06185 pgi -1.3 -4.3 glucose-6-phosphate isomerase compare
BNILDI_04510 pstC -1.3 -2.2 phosphate ABC transporter permease PstC compare
BNILDI_15985 yeaO -1.3 -0.8 Uncharacterized protein YeaO compare
BNILDI_08590 rsmH -1.3 -2.7 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH compare
BNILDI_11900 pdxJ -1.3 -0.7 pyridoxine 5'-phosphate synthase compare
BNILDI_13170 aroC -1.3 -2.5 chorismate synthase compare
BNILDI_15660 yebG -1.3 -1.3 DNA damage-inducible protein YebG compare
BNILDI_09765 speB -1.3 -3.0 agmatinase compare
BNILDI_10495 ygdI -1.3 -1.7 Uncharacterized lipoprotein YgdI compare
BNILDI_16180 ynjA -1.3 -0.6 Uncharacterized protein YnjA compare
BNILDI_21240 tolA -1.3 -3.2 cell envelope integrity protein TolA compare
BNILDI_19800 gfcA -1.3 -1.1 Threonine-rich inner membrane protein GfcA compare
BNILDI_16505 aroD -1.3 -1.4 3-dehydroquinate dehydratase compare
BNILDI_13425 nuoK -1.2 -2.1 NADH-quinone oxidoreductase subunit NuoK compare
BNILDI_09440 -1.2 -1.3 IS4-like element ISVsa5 family transposase compare
BNILDI_18900 fadR -1.2 -2.7 fatty acid metabolism transcriptional regulator FadR compare
BNILDI_21590 Met_trna -1.2 -0.6 tRNA-Met(cat) compare
BNILDI_22735 -1.2 -0.6 DUF1778 domain-containing protein compare
BNILDI_10020 fldB -1.2 -2.5 flavodoxin FldB compare
BNILDI_08070 serB -1.2 -2.6 phosphoserine phosphatase compare
BNILDI_22760 panE -1.2 -3.4 2-dehydropantoate 2-reductase compare
BNILDI_18910 dsbB -1.2 -2.6 disulfide bond formation protein DsbB compare
BNILDI_07065 ulaR -1.2 -1.7 HTH-type transcriptional regulator UlaR compare
BNILDI_15740 yebV -1.2 -2.6 Uncharacterized protein YebV compare
BNILDI_18445 rluB -1.2 -1.8 23S rRNA pseudouridine(2605) synthase RluB compare
BNILDI_15555 -1.2 -1.0 glycosyl hydrolase compare
BNILDI_01535 -1.2 -0.9 UPF0306 protein compare
BNILDI_00865 ygiZ -1.2 -0.9 Inner membrane protein YgiZ compare
BNILDI_14405 yegR -1.2 -0.9 Uncharacterized protein YegR compare
BNILDI_19900 yccX -1.2 -0.5 acylphosphatase compare
BNILDI_07415 -1.2 -0.9 DNA-binding protein compare
BNILDI_12615 -1.1 -1.3 Ethanolamine ammonia lyase large subunit compare
BNILDI_05995 thiF -1.1 -4.3 thiazole biosynthesis adenylyltransferase ThiF compare
BNILDI_01585 yrbN -1.1 -1.9 Uncharacterized protein YrbN compare
BNILDI_08960 yadN -1.1 -1.5 Uncharacterized fimbrial-like protein YadN compare
BNILDI_07450 holC -1.1 -1.7 DNA polymerase III subunit chi compare
BNILDI_04505 pstA -1.1 -1.2 phosphate ABC transporter permease PstA compare
BNILDI_12510 eutQ -1.1 -2.2 ethanolamine utilization acetate kinase EutQ compare
BNILDI_13475 menD -1.1 -1.1 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase compare
BNILDI_10070 ygfS -1.1 -1.1 Putative electron transport protein YgfS compare
BNILDI_15065 dsrB -1.1 -1.2 protein DsrB compare
BNILDI_19365 flgB -1.1 -0.5 flagellar basal body rod protein FlgB compare
BNILDI_01740 mlaC -1.1 -1.2 phospholipid-binding protein MlaC compare
BNILDI_01230 yqiM -1.1 -0.5 Protein YqiM compare
BNILDI_11845 nadB -1.1 -6.2 L-aspartate oxidase compare
BNILDI_09160 skp -1.1 -0.5 molecular chaperone Skp compare
BNILDI_04605 mnmG -1.1 -2.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
BNILDI_09755 speA -1.1 -4.6 biosynthetic arginine decarboxylase compare
BNILDI_06890 epmA -1.1 -0.9 elongation factor P--(R)-beta-lysine ligase compare
BNILDI_01595 pnp -1.1 -3.1 polyribonucleotide nucleotidyltransferase compare
BNILDI_09050 yadS -1.0 -1.2 UPF0126 inner membrane protein YadS compare
BNILDI_14185 btsR -1.0 -1.8 two-component system response regulator BtsR compare
BNILDI_07570 insB -1.0 -0.6 Transposase and inactivated derivatives, IS1 family compare
BNILDI_17850 azoR -1.0 -2.1 FMN-dependent NADH-azoreductase compare
BNILDI_22365 -1.0 -1.7 Protein compare
BNILDI_14340 yegW -1.0 -3.0 Uncharacterized HTH-type transcriptional regulator YegW compare
BNILDI_09090 glnD -1.0 -0.7 bifunctional uridylyltransferase/uridylyl-removing protein GlnD compare
BNILDI_02510 -1.0 -1.1 DUF2559 domain-containing protein compare
BNILDI_04720 maoP -1.0 -4.0 macrodomain Ori organization protein MaoP compare
BNILDI_16340 pfkB -1.0 -1.0 6-phosphofructokinase II compare
BNILDI_18225 pspE -1.0 -1.1 thiosulfate sulfurtransferase PspE compare
BNILDI_20520 ybjQ -1.0 -1.8 UPF0145 protein YbjQ compare
BNILDI_21035 bioF -1.0 -5.0 8-amino-7-oxononanoate synthase compare
BNILDI_15160 yedD -1.0 -1.1 lipoprotein compare
BNILDI_11105 recA -1.0 -1.0 recombinase RecA compare
BNILDI_01345 tdcB -1.0 -2.3 bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB compare
BNILDI_04045 rph -1.0 -1.6 ribonuclease PH compare
BNILDI_17120 ydfZ -1.0 -1.2 Putative selenoprotein YdfZ compare
BNILDI_04085 trmH -1.0 -1.8 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BNILDI_11855 rseA -1.0 -1.3 anti-sigma-E factor RseA compare
BNILDI_11080 srlB -0.9 -0.8 PTS glucitol/sorbitol transporter subunit IIA compare
BNILDI_21980 fepG -0.9 -2.4 iron-enterobactin ABC transporter permease compare
BNILDI_17810 yncP -0.9 -0.6 Protein YncP compare
BNILDI_02780 glpR -0.9 -2.3 DeoR/GlpR family transcriptional regulator compare
BNILDI_04515 pstS -0.9 -2.5 phosphate ABC transporter substrate-binding protein PstS compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC62 in carbon source experiments

For carbon source Casamino-acids across organisms