Experiment set2S751 for Escherichia coli ECRC62

Compare to:

Sodium-DL-Lactate

200 most detrimental genes:

  gene name fitness t score description  
BNILDI_15935 dmlR +1.2 1.7 DNA-binding transcriptional regulator DmlR compare
BNILDI_10860 rpoS +1.2 6.1 RNA polymerase sigma factor RpoS compare
BNILDI_07485 Leu_trna +1.1 1.2 tRNA-Leu(caa) compare
BNILDI_17020 asr +1.1 1.0 acid resistance repetitive basic protein Asr compare
BNILDI_00320 dinJ +1.0 2.9 type II toxin-antitoxin system antitoxin DinJ compare
BNILDI_21470 speFL +1.0 1.2 Leader peptide SpeFL compare
BNILDI_19900 yccX +1.0 0.9 acylphosphatase compare
BNILDI_12530 eutN +1.0 1.1 ethanolamine utilization microcompartment protein EutN compare
BNILDI_02530 nirD +0.9 1.7 nitrite reductase small subunit NirD compare
BNILDI_21805 cspE +0.9 2.6 transcription antiterminator/RNA stability regulator CspE compare
BNILDI_04860 wzyE +0.9 5.2 ECA oligosaccharide polymerase compare
BNILDI_19120 +0.9 2.2 DUF3592 domain-containing protein compare
BNILDI_08235 mokC +0.9 3.2 type I toxin-antitoxin system toxin MokC compare
BNILDI_11455 +0.9 1.8 sporadically distributed , TIGR04141 family protein compare
BNILDI_19365 flgB +0.8 0.9 flagellar basal body rod protein FlgB compare
BNILDI_17295 lsrC +0.8 1.3 autoinducer 2 ABC transporter permease LsrC compare
BNILDI_13965 rihB +0.8 1.9 ribosylpyrimidine nucleosidase compare
BNILDI_12525 eutM +0.8 1.9 ethanolamine utilization microcompartment protein EutM compare
BNILDI_21430 ybfB +0.8 1.1 Uncharacterized protein YbfB compare
BNILDI_00210 +0.8 0.9 hypothetical protein compare
BNILDI_21535 +0.8 1.0 hypothetical protein compare
BNILDI_16785 slyA +0.8 0.9 transcriptional regulator SlyA compare
BNILDI_17340 +0.8 1.3 hypothetical protein compare
BNILDI_09355 rnhA +0.7 2.1 ribonuclease HI compare
BNILDI_10955 hypB +0.7 1.3 hydrogenase nickel incorporation protein HypB compare
BNILDI_20715 +0.7 2.1 CHASE9 sensor domain-containing protein compare
BNILDI_01735 ibaG +0.7 1.9 BolA family iron metabolism protein IbaG compare
BNILDI_16490 ydiP +0.7 1.7 Uncharacterized HTH-type transcriptional regulator YdiP compare
BNILDI_00255 crl +0.7 3.4 sigma factor-binding protein Crl compare
BNILDI_19800 gfcA +0.7 1.5 Threonine-rich inner membrane protein GfcA compare
BNILDI_19290 yceD +0.7 1.1 23S rRNA accumulation protein YceD compare
BNILDI_14685 +0.7 1.4 glycosyltransferase family 1 protein compare
BNILDI_17515 sra +0.7 1.9 stationary-phase-induced ribosome-associated protein compare
BNILDI_13360 yfbR +0.7 1.1 5'-deoxynucleotidase compare
BNILDI_00250 phoE +0.7 2.1 phosphoporin PhoE compare
BNILDI_03955 rfaJ +0.7 4.2 UDP-galactose--(galactosyl) LPS alpha1,2-galactosyltransferase compare
BNILDI_13950 psuG +0.7 1.5 pseudouridine-5'-phosphate glycosidase compare
BNILDI_07380 pyrI +0.7 2.3 aspartate carbamoyltransferase regulatory subunit compare
BNILDI_04815 wzzE +0.6 3.4 ECA polysaccharide chain length modulation protein compare
BNILDI_06875 +0.6 0.5 Fumarate reductase subunit C compare
BNILDI_15205 dcyD +0.6 2.1 D-cysteine desulfhydrase compare
BNILDI_17740 insQ +0.6 2.3 Putative RNA-guided DNA endonuclease InsQ compare
BNILDI_07720 yjiC +0.6 1.1 Uncharacterized protein YjiC compare
BNILDI_07560 +0.6 1.9 PfkB family carbohydrate kinase compare
BNILDI_07090 ulaD +0.6 1.7 3-keto-L-gulonate-6-phosphate decarboxylase UlaD compare
BNILDI_22115 +0.6 1.0 DNA-packaging protein compare
BNILDI_05765 pflC +0.6 2.1 [formate-C-acetyltransferase]-activating enzyme compare
BNILDI_16885 add +0.6 1.3 adenosine deaminase compare
BNILDI_12500 eutS +0.6 2.4 Bacterial microcompartment shell protein EutS compare
BNILDI_04050 yicC +0.6 2.2 UPF0701 protein YicC compare
BNILDI_13070 Arg_trna +0.6 0.6 tRNA-Arg(cct) compare
BNILDI_03825 mtlD +0.6 1.0 mannitol-1-phosphate 5-dehydrogenase compare
BNILDI_05650 hslV +0.6 0.5 ATP-dependent protease subunit HslV compare
BNILDI_13765 napB +0.6 0.8 nitrate reductase cytochrome c-type subunit compare
BNILDI_15100 fliM +0.6 1.4 flagellar motor switch protein FliM compare
BNILDI_17385 ydeO +0.6 1.9 acid stress response transcriptional regulator YdeO compare
BNILDI_04665 rbsR +0.6 4.7 ribose operon transcriptional repressor RbsR compare
BNILDI_00545 +0.6 1.1 Type II secretion protein GspC compare
BNILDI_18510 yciB +0.6 0.8 septation protein A compare
BNILDI_05835 fabR +0.6 2.4 HTH-type transcriptional repressor FabR compare
BNILDI_17095 ynfA +0.6 0.6 YnfA family protein compare
BNILDI_02910 yrhB +0.6 1.2 Uncharacterized protein YrhB compare
BNILDI_19915 yccU +0.6 1.5 Uncharacterized protein YccU compare
BNILDI_13300 folX +0.6 1.1 dihydroneopterin triphosphate 2'-epimerase compare
BNILDI_19475 yceK +0.6 2.4 YceK/YidQ family lipoprotein compare
BNILDI_15120 fliI +0.6 1.6 flagellum-specific ATP synthase FliI compare
BNILDI_10855 nlpD +0.6 3.5 murein hydrolase activator NlpD compare
BNILDI_08260 fimD +0.6 1.1 fimbrial assembly protein compare
BNILDI_16090 ydjF +0.6 2.0 Uncharacterized HTH-type transcriptional regulator YdjF compare
BNILDI_09695 yggU +0.6 1.9 DUF167 domain-containing protein compare
BNILDI_10915 pphB +0.6 1.5 protein-serine/threonine phosphatase compare
BNILDI_14100 ubiH +0.6 2.2 3-hydroxybenzoate 6-monooxygenase compare
BNILDI_17945 paaA +0.6 2.1 1,2-phenylacetyl-CoA epoxidase subunit A compare
BNILDI_19325 flgJ +0.6 2.7 flagellar assembly peptidoglycan hydrolase FlgJ compare
BNILDI_06565 phnK +0.5 1.3 phosphonate C-P lyase system protein PhnK compare
BNILDI_15585 +0.5 1.2 maltose ABC transporter substrate-binding protein compare
BNILDI_09090 glnD +0.5 0.5 bifunctional uridylyltransferase/uridylyl-removing protein GlnD compare
BNILDI_00360 yafV +0.5 2.3 2-oxoglutaramate amidase compare
BNILDI_13010 cscB +0.5 2.3 Sucrose permease compare
BNILDI_08890 yadG +0.5 2.3 Uncharacterized ABC transporter ATP-binding protein YadG compare
BNILDI_11495 +0.5 1.2 hypothetical protein compare
BNILDI_13395 nuoE +0.5 0.7 NADH-quinone oxidoreductase subunit NuoE compare
BNILDI_15595 +0.5 0.5 maltose ABC transporter permease compare
BNILDI_21110 modC +0.5 2.5 molybdenum ABC transporter ATP-binding protein ModC compare
BNILDI_00170 +0.5 2.8 hypothetical protein compare
BNILDI_16005 yeaK +0.5 2.1 mischarged aminoacyl-tRNA deacylase compare
BNILDI_01405 yhaV +0.5 1.7 type II toxin-antitoxin system ribonuclease toxin YhaV compare
BNILDI_00460 +0.5 1.6 hypothetical protein compare
BNILDI_10905 ltnD +0.5 2.0 L-threonate dehydrogenase compare
BNILDI_05645 hslU +0.5 2.3 HslU--HslV peptidase ATPase subunit compare
BNILDI_08525 sgrT +0.5 0.8 Putative inhibitor of glucose uptake transporter SgrT compare
BNILDI_03295 gadE +0.5 3.2 acid resistance transcriptional activator GadE compare
BNILDI_17275 lsrG +0.5 1.6 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase compare
BNILDI_17365 ydeR +0.5 1.1 Uncharacterized fimbrial-like protein YdeR compare
BNILDI_18405 yciX +0.5 1.5 YmiA family putative membrane protein compare
BNILDI_17040 bioD +0.5 1.1 dethiobiotin synthase compare
BNILDI_04660 rbsK +0.5 2.7 ribokinase compare
BNILDI_09475 +0.5 2.4 DNA-binding protein compare
BNILDI_01455 agaB +0.5 2.2 PTS galactosamine transporter subunit IIB compare
BNILDI_02545 yhfL +0.5 0.9 Uncharacterized protein YhfL compare
BNILDI_03105 ptsN +0.5 1.5 PTS suar transporter subunit IIA compare
BNILDI_10055 +0.5 1.6 Small putative membrane protein compare
BNILDI_15820 +0.5 1.3 UPF0266 membrane protein YobD compare
BNILDI_12190 bamB +0.5 1.8 outer membrane protein assembly factor BamB compare
BNILDI_13775 ccmA +0.5 1.1 cytochrome c biogenesis heme-transporting ATPase CcmA compare
BNILDI_14845 yeeT +0.5 2.0 Uncharacterized protein YeeT compare
BNILDI_07020 yjfJ +0.5 1.1 Uncharacterized protein YjfJ compare
BNILDI_07715 uxuR +0.5 0.7 Uxu operon transcriptional regulator compare
BNILDI_08405 kefC +0.4 2.7 glutathione-regulated potassium-efflux system protein KefC compare
BNILDI_15600 +0.4 0.4 alpha-glycosidase compare
BNILDI_09415 +0.4 0.8 amino acid-binding protein compare
BNILDI_01265 doxX +0.4 1.6 DoxX family protein compare
BNILDI_01110 ebgR +0.4 2.0 transcriptional regulator EbgR compare
BNILDI_00485 +0.4 1.4 Mutator family transposase compare
BNILDI_14050 yeiS +0.4 0.5 Uncharacterized protein YeiS compare
BNILDI_07935 yjjB +0.4 0.9 threonine/serine exporter compare
BNILDI_17670 ydcY +0.4 0.9 Uncharacterized protein YdcY compare
BNILDI_15220 sdiA +0.4 2.2 transcriptional regulator SdiA compare
BNILDI_19510 +0.4 1.3 Uncharacterized protein YmdA compare
BNILDI_19000 ymgF +0.4 0.6 Inner membrane protein YmgF compare
BNILDI_01870 nanK +0.4 2.0 N-acetylmannosamine kinase compare
BNILDI_02695 ompR_G63V +0.4 2.1 two-component system response regulator OmpR compare
BNILDI_13265 argT +0.4 1.4 lysine/arginine/ornithine ABC transporter substrate-binding protein ArgT compare
BNILDI_00285 yhbS +0.4 1.4 GNAT family N-acetyltransferase compare
BNILDI_08425 rsmA +0.4 0.7 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA compare
BNILDI_19425 dinI +0.4 1.0 DNA damage-inducible protein I compare
BNILDI_15125 fliH +0.4 0.4 flagellar assembly protein FliH compare
BNILDI_02505 fic +0.4 2.2 putative adenosine monophosphate-protein transferase Fic compare
BNILDI_06985 hflC +0.4 1.7 protease modulator HflC compare
BNILDI_15470 yecE +0.4 1.9 UPF0759 protein YecE compare
BNILDI_22970 iraP +0.4 1.5 anti-adapter protein IraP compare
BNILDI_14600 wcaI +0.4 1.2 colanic acid biosynthesis fucosyltransferase WcaI compare
BNILDI_00395 tnp-ISAs1 +0.4 1.2 ISAs1 family transposase compare
BNILDI_03595 cspA +0.4 0.3 Major cold shock protein compare
BNILDI_16465 ydiT +0.4 1.4 Ferredoxin-like protein YdiT compare
BNILDI_20700 +0.4 1.5 EAL domain-containing protein compare
BNILDI_16880 ydgJ +0.4 2.5 Uncharacterized oxidoreductase YdgJ compare
BNILDI_12320 hyfI +0.4 1.0 hydrogenase 4 catalytic subunit HyfI compare
BNILDI_20820 +0.4 1.4 Outer membrane protein X compare
BNILDI_09730 rsmE +0.4 0.4 16S rRNA (uracil(1498)-N(3))-methyltransferase compare
BNILDI_15605 +0.4 0.6 metal-dependent hydrolase compare
BNILDI_13230 +0.4 1.3 DedA family inner membrane protein compare
BNILDI_11470 +0.4 1.0 nuclease compare
BNILDI_04600 rsmG +0.4 2.5 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG compare
BNILDI_11285 csiR +0.4 1.5 DNA-binding transcriptional regulator CsiR compare
BNILDI_17300 lsrA +0.4 1.8 autoinducer 2 ABC transporter ATP-binding protein LsrA compare
BNILDI_01030 plsY +0.4 1.6 glycerol-3-phosphate 1-O-acyltransferase PlsY compare
BNILDI_11830 yfiE +0.4 2.0 Uncharacterized HTH-type transcriptional regulator YfiE compare
BNILDI_21890 +0.4 2.5 Alkyl hydroperoxide reductase subunit F compare
BNILDI_10370 ptsP +0.4 2.7 phosphoenolpyruvate--protein phosphotransferase compare
BNILDI_08875 +0.4 1.6 hypothetical protein compare
BNILDI_06540 phnP +0.4 1.0 phosphonate metabolism protein PhnP compare
BNILDI_22265 arcC +0.4 1.1 carbamate kinase compare
BNILDI_09525 zorB +0.4 1.1 Zorya protein ZorB compare
BNILDI_10535 fucI +0.4 2.0 L-fucose isomerase compare
BNILDI_19985 pqiB +0.4 1.8 intermembrane transport protein PqiB compare
BNILDI_01740 mlaC +0.4 0.7 phospholipid-binding protein MlaC compare
BNILDI_12125 pepB +0.4 1.6 aminopeptidase PepB compare
BNILDI_14295 rcnA +0.4 1.5 nickel/cobalt efflux protein RcnA compare
BNILDI_07725 idlP +0.4 1.6 iraD leader peptide compare
BNILDI_08495 yabI +0.4 1.2 Inner membrane protein YabI compare
BNILDI_15115 fliJ +0.4 0.7 flagella biosynthesis chaperone FliJ compare
BNILDI_02795 glpD +0.4 1.4 glycerol-3-phosphate dehydrogenase compare
BNILDI_22740 +0.4 1.7 N-acetyltransferase compare
BNILDI_12750 cysZ +0.4 2.6 sulfate transporter CysZ compare
BNILDI_12665 yfeX +0.4 1.2 porphyrinogen peroxidase compare
BNILDI_08090 ettA +0.4 1.7 energy-dependent translational throttle protein EttA compare
BNILDI_11730 rluD +0.4 2.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD compare
BNILDI_00585 glcF +0.4 2.4 glycolate oxidase subunit GlcF compare
BNILDI_15075 fliR +0.4 1.5 flagellar type III secretion system protein FliR compare
BNILDI_15800 cspE +0.4 0.8 transcription antiterminator/RNA stability regulator CspE compare
BNILDI_19255 fabF +0.4 1.8 beta-ketoacyl-ACP synthase II compare
BNILDI_18595 insZ +0.4 1.5 IS4 family transposase compare
BNILDI_14110 yohP +0.4 0.4 protein YohP compare
BNILDI_20510 ybjS +0.4 2.1 Uncharacterized protein YbjS compare
BNILDI_13570 glpC +0.4 1.9 anaerobic glycerol-3-phosphate dehydrogenase subunit GlpC compare
BNILDI_09765 speB +0.4 1.5 agmatinase compare
BNILDI_17110 ydfJ +0.4 1.1 MHS family MFS transporter YdfJ compare
BNILDI_09480 +0.4 1.8 hypothetical protein compare
BNILDI_19055 rluE +0.4 2.3 23S rRNA pseudouridine(2457) synthase RluE compare
BNILDI_03300 +0.4 1.6 hypothetical protein compare
BNILDI_12850 ypeC +0.4 1.2 Uncharacterized protein YpeC compare
BNILDI_14275 yehC +0.4 0.4 putative fimbrial chaperone YehC compare
BNILDI_07205 qorB +0.4 1.6 NAD(P)H:quinone oxidoreductase compare
BNILDI_06265 +0.4 1.7 hypothetical protein compare
BNILDI_04385 ysdD +0.4 0.9 Protein YsdD compare
BNILDI_00990 +0.4 0.7 Type I toxin-antitoxin system Ibs family toxin compare
BNILDI_02805 +0.4 1.7 hypothetical protein compare
BNILDI_07000 nsrR +0.4 1.6 nitric oxide-sensing transcriptional repressor NsrR compare
BNILDI_12035 hcaB +0.4 1.5 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase compare
BNILDI_07870 hpcD +0.4 0.3 5-carboxymethyl-2-hydroxymuconate Delta-isomerase compare
BNILDI_01685 yhbY +0.4 1.5 ribosome assembly RNA-binding protein YhbY compare
BNILDI_22305 glxK +0.4 1.7 glycerate 3-kinase compare
BNILDI_13855 rsuA +0.4 1.9 16S rRNA pseudouridine(516) synthase RsuA compare
BNILDI_18290 ymjA +0.4 0.9 Uncharacterized protein YmjA compare
BNILDI_11530 +0.4 0.4 DUF2732 domain-containing protein compare
BNILDI_14760 yeeY +0.4 2.3 Uncharacterized HTH-type transcriptional regulator YeeY compare
BNILDI_19370 flgA +0.4 1.5 flagellar basal body P-ring formation protein FlgA compare
BNILDI_10900 otnK +0.4 1.3 3-oxo-tetronate kinase compare
BNILDI_18980 ymgG +0.4 0.6 UPF0757 protein YmgG compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC62 in carbon source experiments

For carbon source Sodium-DL-Lactate across organisms