Experiment set2S715 for Escherichia coli ECRC62

Compare to:

D-Glucose

200 most important genes:

  gene name fitness t score description  
BNILDI_03980 rfaG -8.5 -4.2 Lipopolysaccharide core biosynthesis protein RfaG compare
BNILDI_08535 leuD -8.1 -6.8 3-isopropylmalate dehydratase small subunit compare
BNILDI_08980 dksA -7.6 -7.4 RNA polymerase-binding protein DksA compare
BNILDI_08170 thrC -7.5 -4.2 threonine synthase compare
BNILDI_21240 tolA -6.9 -4.7 cell envelope integrity protein TolA compare
BNILDI_13170 aroC -6.7 -4.0 chorismate synthase compare
BNILDI_11985 glyA -6.2 -2.8 serine hydroxymethyltransferase compare
BNILDI_04750 ilvD -6.2 -15.3 dihydroxy-acid dehydratase compare
BNILDI_14720 hisA -6.1 -2.8 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase compare
BNILDI_18870 ldcA -5.8 -6.5 muramoyltetrapeptide carboxypeptidase compare
BNILDI_03970 waaO -5.8 -4.4 lipopolysaccharide 3-alpha-galactosyltransferase compare
BNILDI_20300 aroA -5.6 -15.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BNILDI_06060 purD -5.5 -14.7 Phosphoribosylamine--glycine ligase compare
BNILDI_08540 leuC1 -5.5 -12.5 3-isopropylmalate dehydratase large subunit 1 compare
BNILDI_04850 wzxE -5.4 -3.7 lipid III flippase WzxE compare
BNILDI_12215 guaA -5.4 -5.2 glutamine-hydrolyzing GMP synthase compare
BNILDI_02615 aroB -5.4 -9.6 3-dehydroquinate synthase compare
BNILDI_06065 purH -5.3 -14.6 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
BNILDI_16505 aroD -5.2 -5.0 3-dehydroquinate dehydratase compare
BNILDI_04765 ilvC -5.1 -13.2 ketol-acid reductoisomerase compare
BNILDI_12400 purC -5.1 -7.2 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BNILDI_05725 metF -5.1 -14.1 methylenetetrahydrofolate reductase compare
BNILDI_11945 purL -5.0 -17.5 phosphoribosylformylglycinamidine synthase compare
BNILDI_08070 serB -4.9 -8.0 phosphoserine phosphatase compare
BNILDI_08545 leuA -4.9 -8.2 2-isopropylmalate synthase compare
BNILDI_12210 guaB -4.9 -5.8 IMP dehydrogenase compare
BNILDI_06995 purA -4.9 -3.4 adenylosuccinate synthase compare
BNILDI_20305 serC -4.7 -11.8 3-phosphoserine/phosphohydroxythreonine transaminase compare
BNILDI_12270 purM -4.7 -9.0 Phosphoribosylformylglycinamidine cyclo-ligase compare
BNILDI_14725 hisH -4.6 -5.4 imidazole glycerol phosphate synthase subunit HisH compare
BNILDI_08550 -4.5 -11.4 2-isopropylmalate synthase compare
BNILDI_13255 purF -4.5 -12.1 amidophosphoribosyltransferase compare
BNILDI_11900 pdxJ -4.5 -1.5 pyridoxine 5'-phosphate synthase compare
BNILDI_22255 purE -4.3 -3.9 N5-carboxyaminoimidazole ribonucleotide mutase compare
BNILDI_18465 -4.2 -14.3 hypothetical protein compare
BNILDI_14740 hisD -4.2 -9.1 Histidinol dehydrogenase compare
BNILDI_05075 metE -4.2 -18.6 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase compare
BNILDI_18610 hns -4.2 -1.3 DNA-binding transcriptional regulator H-NS compare
BNILDI_21245 tolR -4.1 -1.3 colicin uptake protein TolR compare
BNILDI_18475 trpB -4.1 -8.5 tryptophan synthase subunit beta compare
BNILDI_01645 argG -4.0 -13.3 argininosuccinate synthase compare
BNILDI_21485 pgm -4.0 -3.4 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) compare
BNILDI_04760 ilvY -3.9 -7.8 HTH-type transcriptional activator IlvY compare
BNILDI_18470 trpD -3.9 -13.6 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
BNILDI_08770 aceF -3.9 -2.3 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase compare
BNILDI_08330 carB -3.9 -13.1 carbamoyl-phosphate synthase large subunit compare
BNILDI_21250 tolQ -3.9 -3.7 Tol-Pal system protein TolQ compare
BNILDI_21230 pal -3.9 -7.0 peptidoglycan-associated lipoprotein Pal compare
BNILDI_22950 proC -3.9 -11.8 pyrroline-5-carboxylate reductase compare
BNILDI_21310 sucA -3.9 -7.8 2-oxoglutarate dehydrogenase E1 component compare
BNILDI_21235 tolB -3.9 -8.9 Tol-Pal system protein TolB compare
BNILDI_11705 pheA -3.8 -5.4 bifunctional chorismate mutase/prephenate dehydratase compare
BNILDI_11700 tyrA -3.8 -9.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BNILDI_09905 serA -3.8 -6.7 phosphoglycerate dehydrogenase compare
BNILDI_00245 proB -3.8 -8.9 Glutamate 5-kinase compare
BNILDI_10310 lysA -3.8 -8.9 diaminopimelate decarboxylase compare
BNILDI_14735 hisC -3.8 -8.1 histidinol-phosphate transaminase compare
BNILDI_20015 pyrD -3.7 -7.0 quinone-dependent dihydroorotate dehydrogenase compare
BNILDI_14715 hisF -3.7 -5.4 Imidazole glycerol phosphate synthase subunit HisF compare
BNILDI_08165 thrB -3.7 -8.9 homoserine kinase compare
BNILDI_08325 carA -3.7 -7.0 carbamoyl phosphate synthase small subunit compare
BNILDI_18480 trpA -3.6 -8.1 tryptophan synthase subunit alpha compare
BNILDI_04745 ilvE -3.6 -10.7 branched-chain-amino-acid transaminase compare
BNILDI_02165 aroE -3.5 -5.7 shikimate dehydrogenase compare
BNILDI_05070 metR -3.5 -10.3 HTH-type transcriptional regulator MetR compare
BNILDI_08155 -3.5 -1.0 thr operon leader peptide compare
BNILDI_10745 cysH -3.4 -8.3 phosphoadenosine phosphosulfate reductase compare
BNILDI_18365 pyrF -3.4 -6.2 orotidine-5'-phosphate decarboxylase compare
BNILDI_07425 argF -3.3 -11.5 ornithine carbamoyltransferase compare
BNILDI_00240 proA -3.3 -8.3 glutamate-5-semialdehyde dehydrogenase compare
BNILDI_05805 argH -3.3 -5.8 argininosuccinate lyase compare
BNILDI_00780 metC -3.2 -9.8 cystathionine beta-lyase compare
BNILDI_07225 cysQ -3.1 -9.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BNILDI_14710 hisIE -3.1 -7.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
BNILDI_06965 miaA -3.0 -2.4 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
BNILDI_05795 argC -3.0 -10.3 N-acetyl-gamma-glutamyl-phosphate reductase compare
BNILDI_19420 pyrC -3.0 -8.6 dihydroorotase compare
BNILDI_10735 cysJ -2.9 -13.4 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit compare
BNILDI_08160 thrA -2.8 -11.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BNILDI_15520 ruvB -2.8 -2.2 Holliday junction branch migration DNA helicase RuvB compare
BNILDI_10815 cysC -2.8 -10.7 Adenylyl-sulfate kinase compare
BNILDI_07385 pyrB -2.8 -8.1 aspartate carbamoyltransferase compare
BNILDI_10425 argA -2.8 -7.1 amino-acid N-acetyltransferase compare
BNILDI_14730 hisB -2.8 -5.4 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB compare
BNILDI_04035 pyrE -2.8 -8.9 Orotate phosphoribosyltransferase compare
BNILDI_10740 cysI -2.7 -9.6 assimilatory sulfite reductase (NADPH) hemoprotein subunit compare
BNILDI_06100 metA -2.7 -7.5 homoserine O-succinyltransferase compare
BNILDI_04205 ivbL -2.6 -0.9 ilvB operon leader peptide IvbL compare
BNILDI_12710 cysA -2.6 -1.5 sulfate/thiosulfate ABC transporter ATP-binding protein CysA compare
BNILDI_10305 lysR -2.6 -7.1 DNA-binding transcriptional regulator LysR compare
BNILDI_05785 ppc -2.6 -11.2 phosphoenolpyruvate carboxylase compare
BNILDI_05790 argE -2.6 -10.2 acetylornithine deacetylase compare
BNILDI_15150 yedF -2.6 -1.0 sulfurtransferase-like selenium metabolism protein YedF compare
BNILDI_10365 rppH -2.6 -1.4 RNA pyrophosphohydrolase compare
BNILDI_21340 gltA -2.5 -6.9 citrate synthase compare
BNILDI_05800 -2.5 -8.2 acetylglutamate kinase compare
BNILDI_08555 leuL -2.5 -1.1 leu operon leader peptide compare
BNILDI_10025 xerD -2.5 -2.3 site-specific tyrosine recombinase XerD compare
BNILDI_22260 purK -2.5 -7.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BNILDI_08430 pdxA -2.5 -7.7 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BNILDI_22670 lon_P403L -2.5 -5.0 Lon protease compare
BNILDI_20395 ftsK -2.4 -5.8 DNA translocase FtsK compare
BNILDI_10805 cysD -2.4 -10.0 sulfate adenylyltransferase subunit CysD compare
BNILDI_13215 pdxB -2.4 -8.0 4-phosphoerythronate dehydrogenase PdxB compare
BNILDI_05715 metB -2.3 -9.7 cystathionine gamma-synthase compare
BNILDI_05565 pfkA -2.3 -5.2 6-phosphofructokinase compare
BNILDI_10810 cysN -2.3 -8.3 sulfate adenylyltransferase subunit CysN compare
BNILDI_11265 ygaP -2.3 -1.0 thiosulfate sulfurtransferase YgaP compare
BNILDI_12745 cysK -2.2 -8.2 cysteine synthase A compare
BNILDI_12705 cysW -2.2 -5.9 sulfate/thiosulfate ABC transporter permease CysW compare
BNILDI_04755 ilvA -2.1 -5.8 threonine ammonia-lyase, biosynthetic compare
BNILDI_12700 cysT -2.1 -5.0 sulfate/thiosulfate ABC transporter permease CysT compare
BNILDI_12290 arsC -2.1 -1.8 arsenate reductase (glutaredoxin) compare
BNILDI_08415 apaH -2.1 -5.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
BNILDI_13250 cvpA -2.0 -4.7 colicin V production protein compare
BNILDI_05905 Tyr_trna -2.0 -1.0 tRNA-Tyr(gta) compare
BNILDI_05005 corA -2.0 -2.0 magnesium/cobalt transporter CorA compare
BNILDI_14745 hisG -1.9 -8.3 ATP phosphoribosyltransferase compare
BNILDI_19225 ptsG -1.9 -6.6 PTS glucose transporter subunit IIBC compare
BNILDI_08435 surA -1.9 -5.1 peptidylprolyl isomerase SurA compare
BNILDI_10405 recC -1.9 -3.3 exodeoxyribonuclease V subunit gamma compare
BNILDI_02540 cysG -1.8 -7.6 siroheme synthase CysG compare
BNILDI_10630 relA -1.8 -8.2 GTP diphosphokinase compare
BNILDI_20400 lrp -1.8 -6.6 leucine-responsive transcriptional regulator Lrp compare
BNILDI_12105 hscB -1.8 -1.2 co-chaperone HscB compare
BNILDI_22735 -1.8 -0.9 DUF1778 domain-containing protein compare
BNILDI_15485 nudB -1.8 -2.8 dihydroneopterin triphosphate diphosphatase compare
BNILDI_02205 trkA -1.8 -1.5 Trk system potassium transporter TrkA compare
BNILDI_19070 hflD -1.7 -2.1 high frequency lysogenization protein HflD compare
BNILDI_04505 pstA -1.7 -1.1 phosphate ABC transporter permease PstA compare
BNILDI_08765 aceE -1.6 -4.3 pyruvate dehydrogenase (acetyl-transferring), homodimeric type compare
BNILDI_21775 lipB -1.6 -0.8 lipoyl(octanoyl) transferase LipB compare
BNILDI_06185 pgi -1.6 -7.0 glucose-6-phosphate isomerase compare
BNILDI_21590 Met_trna -1.6 -0.9 tRNA-Met(cat) compare
BNILDI_03260 -1.6 -0.8 YhiS compare
BNILDI_14525 dcd -1.6 -2.8 dCTP deaminase compare
BNILDI_03975 rfaP -1.6 -1.9 lipopolysaccharide core heptose(I) kinase RfaP compare
BNILDI_12695 cysP -1.5 -5.7 thiosulfate/sulfate ABC transporter substrate-binding protein CysP compare
BNILDI_01595 pnp -1.5 -5.1 polyribonucleotide nucleotidyltransferase compare
BNILDI_03945 -1.5 -3.8 O-antigen ligase domain-containing protein compare
BNILDI_04970 yifL -1.5 -3.8 Uncharacterized lipoprotein YifL compare
BNILDI_04605 mnmG -1.5 -2.6 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
BNILDI_00495 tnpB -1.4 -1.0 IS66 family insertion sequence element accessory protein TnpB compare
BNILDI_15125 fliH -1.4 -0.9 flagellar assembly protein FliH compare
BNILDI_21490 seqA -1.4 -1.6 replication initiation negative regulator SeqA compare
BNILDI_11695 aroF -1.4 -4.4 3-deoxy-7-phosphoheptulonate synthase AroF compare
BNILDI_07450 holC -1.4 -4.3 DNA polymerase III subunit chi compare
BNILDI_18445 rluB -1.4 -2.6 23S rRNA pseudouridine(2605) synthase RluB compare
BNILDI_04720 maoP -1.4 -5.4 macrodomain Ori organization protein MaoP compare
BNILDI_12265 purN -1.4 -5.3 phosphoribosylglycinamide formyltransferase compare
BNILDI_04985 xerC -1.4 -1.5 tyrosine recombinase XerC compare
BNILDI_05720 metL -1.3 -6.9 bifunctional aspartate kinase/homoserine dehydrogenase II compare
BNILDI_04795 trxA -1.3 -3.7 thioredoxin TrxA compare
BNILDI_09040 yadW -1.3 -0.8 Protein YadW compare
BNILDI_10345 ygdR -1.3 -1.2 lipoprotein YgdR compare
BNILDI_21075 -1.3 -1.0 hypothetical protein compare
BNILDI_15660 yebG -1.3 -1.4 DNA damage-inducible protein YebG compare
BNILDI_21535 -1.3 -0.9 hypothetical protein compare
BNILDI_05125 tatC -1.2 -5.6 Sec-independent protein translocase subunit TatC compare
BNILDI_08785 acnB -1.2 -2.2 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
BNILDI_15650 kdgA -1.2 -3.6 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase compare
BNILDI_20405 trxB -1.2 -1.9 thioredoxin-disulfide reductase compare
BNILDI_17810 yncP -1.2 -0.9 Protein YncP compare
BNILDI_21985 fepC -1.1 -3.4 ferrienterobactin ABC transporter ATPase compare
BNILDI_01805 ptsN -1.1 -2.6 PTS IIA-like nitrogen regulatory protein PtsN compare
BNILDI_15795 yebO -1.1 -1.1 Uncharacterized protein YebO compare
BNILDI_21100 pgl -1.1 -4.1 6-phosphogluconolactonase compare
BNILDI_01905 sspA -1.1 -3.9 stringent starvation protein A compare
BNILDI_22685 clpP -1.1 -3.5 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
BNILDI_04510 pstC -1.1 -2.2 phosphate ABC transporter permease PstC compare
BNILDI_10415 recB -1.1 -0.8 exodeoxyribonuclease V subunit beta compare
BNILDI_21185 nadA -1.1 -3.5 quinolinate synthase NadA compare
BNILDI_14685 -1.1 -1.4 glycosyltransferase family 1 protein compare
BNILDI_21625 corC -1.1 -1.6 CNNM family magnesium/cobalt transport protein CorC compare
BNILDI_22680 clpX -1.1 -2.3 ATP-dependent protease ATP-binding subunit ClpX compare
BNILDI_03590 yiaG -1.1 -1.2 HTH-type transcriptional regulator compare
BNILDI_12615 -1.1 -1.7 Ethanolamine ammonia lyase large subunit compare
BNILDI_02605 dam -1.0 -3.1 adenine-specific DNA-methyltransferase compare
BNILDI_11405 -1.0 -1.0 Cell wall-binding protein compare
BNILDI_03965 rfaJ -1.0 -1.5 lipopolysaccharide 1,2-glucosyltransferase compare
BNILDI_19705 rutF -1.0 -1.2 malonic semialdehyde reductase compare
BNILDI_21980 fepG -1.0 -2.4 iron-enterobactin ABC transporter permease compare
BNILDI_08920 panC -1.0 -3.8 pantoate--beta-alanine ligase compare
BNILDI_04715 hdfR -1.0 -5.6 HTH-type transcriptional regulator HdfR compare
BNILDI_06320 yjbM -1.0 -0.9 Uncharacterized protein YjbM compare
BNILDI_20075 -1.0 -2.3 capsular biosynthesis protein compare
BNILDI_14285 yehA -1.0 -0.6 putative fimbrial-like adhesin protein compare
BNILDI_01850 gltB -1.0 -7.2 glutamate synthase large subunit compare
BNILDI_15640 zwf -1.0 -3.4 glucose-6-phosphate dehydrogenase compare
BNILDI_15535 znuA -1.0 -2.9 zinc ABC transporter substrate-binding protein ZnuA compare
BNILDI_14330 -1.0 -2.9 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BNILDI_12155 ndk -1.0 -4.8 nucleoside-diphosphate kinase compare
BNILDI_13165 prmB -1.0 -4.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BNILDI_15555 -1.0 -0.9 glycosyl hydrolase compare
BNILDI_11600 smpB -0.9 -1.2 SsrA-binding protein SmpB compare
BNILDI_06360 -0.9 -0.9 hypothetical protein compare
BNILDI_16405 -0.9 -1.1 Integration host factor subunit alpha compare
BNILDI_12510 eutQ -0.9 -2.6 ethanolamine utilization acetate kinase EutQ compare
BNILDI_19750 torD -0.9 -2.0 molecular chaperone TorD compare
BNILDI_04405 -0.9 -2.3 tRNA modification GTPase MnmE compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC62 in carbon source experiments

For carbon source D-Glucose across organisms