Experiment set2S491 for Hydrogenophaga sp. GW460-11-11-14-LB1

Compare to:

Ying_all64 rep C; time point 3

200 most detrimental genes:

  gene name fitness t score description  
GFF4890 +7.3 47.0 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF3587 +5.9 29.8 Formiminoglutamase (EC 3.5.3.8) compare
GFF3842 +5.7 47.7 FIG01199081: hypothetical protein compare
GFF781 +5.6 14.8 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) compare
GFF1972 +5.5 32.9 Transcriptional regulator compare
GFF3773 +5.5 28.2 Transcriptional regulator, MarR family compare
GFF2567 +5.4 19.2 Preprotein translocase subunit YajC (TC 3.A.5.1.1) compare
GFF1225 +5.4 9.3 FIG136845: Rhodanese-related sulfurtransferase compare
GFF779 +5.2 27.2 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) compare
GFF831 +5.1 18.0 Heat-inducible transcription repressor HrcA compare
GFF780 +5.0 15.6 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
GFF4311 +4.8 28.4 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein compare
GFF2038 +4.7 10.9 Gamma-glutamyl-GABA hydrolase (EC 3.5.1.94) compare
GFF4043 +4.5 35.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF2610 +4.2 33.3 Patatin compare
GFF1610 +4.1 6.8 hypothetical protein compare
GFF4521 +4.1 25.6 ATP-dependent Clp protease ATP-binding subunit ClpA compare
GFF1011 +3.8 28.8 Transcriptional regulator, IclR family compare
GFF4277 +3.8 7.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
GFF2738 +3.5 24.9 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare
GFF723 +3.5 25.5 Deacetylases, including yeast histone deacetylase and acetoin utilization protein compare
GFF4042 +3.4 16.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF1294 +3.2 8.8 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
GFF3698 +3.2 7.3 NAD-specific glutamate dehydrogenase (EC 1.4.1.2); NADP-specific glutamate dehydrogenase (EC 1.4.1.4) compare
GFF4257 +3.2 19.6 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) compare
GFF2043 +3.2 25.8 Glycine/D-amino acid oxidase (deaminating) in putrescine utilization cluster compare
GFF4226 +3.2 27.5 Polyphosphate kinase (EC 2.7.4.1) compare
GFF1895 +3.0 13.7 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) compare
GFF518 +2.9 8.1 Transcriptional regulator compare
GFF1389 +2.8 3.3 General secretion pathway protein N compare
GFF2537 +2.8 5.4 Two-component response regulator compare
GFF3309 +2.7 13.7 Uricase (urate oxidase) (EC 1.7.3.3) compare
GFF5027 +2.7 8.4 Sulfate and thiosulfate binding protein CysP compare
GFF3441 +2.7 14.4 Cation transport protein chaC compare
GFF2897 +2.7 10.8 Enoyl-CoA hydratase (EC 4.2.1.17) compare
GFF595 +2.7 9.1 two component, sigma54 specific, transcriptional regulator, Fis family compare
GFF803 +2.7 11.7 PQQ-dependent oxidoreductase, gdhB family compare
GFF651 +2.7 10.0 Aspartate carbamoyltransferase (EC 2.1.3.2) compare
GFF1293 +2.5 8.9 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
GFF4856 +2.5 15.9 HflK protein compare
GFF5759 +2.5 15.5 Glutaryl-CoA dehydrogenase (EC 1.3.99.7) compare
GFF3420 +2.4 12.9 Acetylornithine aminotransferase (EC 2.6.1.11) compare
GFF2931 +2.4 17.4 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
GFF124 +2.4 17.3 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF828 +2.4 7.1 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
GFF4271 +2.3 13.6 NAD synthetase (EC 6.3.1.5) / Glutamine amidotransferase chain of NAD synthetase compare
GFF3060 +2.3 17.5 Lysine 2-monooxygenase (EC 1.13.12.2) compare
GFF5228 +2.2 18.7 Transcriptional regulator, TetR family compare
GFF5431 +2.2 2.7 Vitamin B12 ABC transporter, permease component BtuC compare
GFF5731 +2.2 16.4 3'-to-5' oligoribonuclease (orn) compare
GFF1331 +2.2 16.6 3-dehydroquinate synthase (EC 4.2.3.4) compare
GFF5509 +2.2 9.9 Gluconate utilization system Gnt-I transcriptional repressor compare
GFF1715 +2.2 18.4 Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) compare
GFF2536 +2.2 11.7 two-component hybrid sensor and regulator compare
GFF5025 +2.1 1.7 hypothetical protein compare
GFF2780 +2.1 10.7 Pyruvate kinase (EC 2.7.1.40) compare
GFF5399 +2.1 9.7 autotransporter compare
GFF4926 +2.0 8.8 Alpha/beta hydrolase fold compare
GFF401 +2.0 10.9 Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A compare
GFF4592 +2.0 14.1 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
GFF652 +1.9 3.2 Dihydroorotase (EC 3.5.2.3) compare
GFF1924 +1.9 2.6 MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein compare
GFF2645 +1.9 5.6 Glutamate--cysteine ligase (EC 6.3.2.2), divergent, of Alpha- and Beta-proteobacteria type compare
GFF2715 +1.9 2.4 rRNA small subunit methyltransferase I compare
GFF2896 +1.9 7.4 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
GFF3588 +1.9 4.1 Imidazolonepropionase (EC 3.5.2.7) compare
GFF519 +1.9 4.3 Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4) compare
GFF2035 +1.9 15.9 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
GFF5028 +1.9 2.1 FMN reductase (EC 1.5.1.29) compare
GFF829 +1.8 5.3 DNA repair protein RecN compare
GFF2034 +1.8 13.9 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
GFF2032 +1.8 14.5 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
GFF3170 +1.8 2.0 hypothetical protein compare
GFF4794 +1.8 12.5 TrkA-N:Sodium/hydrogen exchanger compare
GFF4874 +1.8 14.3 ATPase component BioM of energizing module of biotin ECF transporter compare
GFF2469 +1.7 12.5 NADP-dependent malic enzyme (EC 1.1.1.40) compare
GFF1971 +1.7 12.4 Transcriptional regulator, TetR family compare
GFF4180 +1.7 2.3 Conjugative transfer protein TrbJ compare
GFF2033 +1.7 15.4 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare
GFF2244 +1.7 1.7 putative exported protein compare
GFF5072 +1.7 1.9 Taurine transport ATP-binding protein TauB compare
GFF2044 +1.7 5.1 Agmatinase (EC 3.5.3.11) compare
GFF3980 +1.7 3.7 Vitamin B12 ABC transporter, B12-binding component BtuF compare
GFF2040 +1.7 12.4 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
GFF627 +1.7 6.3 N-formylglutamate deformylase (EC 3.5.1.68) compare
GFF1716 +1.7 9.7 Transcriptional regulator, AraC family compare
GFF771 +1.7 7.7 LSU ribosomal protein L33p compare
GFF500 +1.6 1.7 Type III secretion inner membrane protein (YscS,homologous to flagellar export components) compare
GFF1651 +1.6 1.7 Ureidoglycolate hydrolase (EC 3.5.3.19) compare
GFF1204 +1.6 8.2 Regulatory protein of benzoate catabolism compare
GFF3934 +1.6 9.0 Aspartate aminotransferase (EC 2.6.1.1) compare
GFF2463 +1.6 11.7 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases compare
GFF4855 +1.6 9.4 HflC protein compare
GFF1194 +1.6 1.7 Formate dehydrogenase subunit or accessory protein compare
GFF202 +1.6 1.5 Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4) compare
GFF1239 +1.5 6.0 FIG00933538: hypothetical protein compare
GFF5034 +1.5 1.3 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components compare
GFF2566 +1.5 12.9 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits compare
GFF2576 +1.5 1.7 Probable transmembrane protein compare
GFF5493 +1.5 11.4 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
GFF4892 +1.5 12.3 Probable two-component transmembrane sensor histidine kinase transcription regulator protein (EC 2.7.3.-) compare
GFF3738 +1.5 1.1 hypothetical protein compare
GFF119 +1.5 7.3 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) compare
GFF3061 +1.5 4.1 FIG00931323: hypothetical protein compare
GFF1488 +1.5 2.4 Two-component system response regulator compare
GFF3526 +1.5 6.2 Lipid A export ATP-binding/permease protein MsbA compare
GFF1919 +1.5 5.6 Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF compare
GFF4041 +1.5 2.6 hypothetical protein compare
GFF596 +1.5 11.6 Two-component sensor PilS compare
GFF1086 +1.4 2.5 hypothetical protein compare
GFF1250 +1.4 5.7 Transporter compare
GFF4908 +1.4 10.0 Membrane-associated zinc metalloprotease compare
GFF2733 +1.4 7.7 Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD compare
GFF5394 +1.4 5.0 FIG01210906: hypothetical protein compare
GFF3887 +1.4 2.7 hypothetical protein compare
GFF4803 +1.4 3.5 Transcriptional regulator, GntR family compare
GFF5130 +1.4 2.0 Tricarboxylate transport transcriptional regulator TctD compare
GFF3442 +1.4 1.9 Cytochrome c oxidase polypeptide II (EC 1.9.3.1) compare
GFF3141 +1.4 2.7 hypothetical protein compare
GFF131 +1.4 1.7 TRAP dicarboxylate transporter, DctQ subunit, unknown substrate 3 compare
GFF2448 +1.4 2.7 Methionine biosynthesis protein MetW compare
GFF581 +1.4 9.3 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
GFF1913 +1.4 4.0 Permease of the drug/metabolite transporter (DMT) superfamily compare
GFF2654 +1.4 4.4 Na(+) H(+) antiporter subunit F compare
GFF5244 +1.3 1.9 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
GFF1318 +1.3 9.7 ABC-type multidrug transport system, permease component compare
GFF1740 +1.3 7.4 Transcriptional regulator, AsnC family compare
GFF3308 +1.3 4.4 N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) compare
GFF526 +1.3 2.6 Heat shock protease compare
GFF24 +1.3 1.1 Hydroxymethylpyrimidine ABC transporter, transmembrane component compare
GFF1882 +1.3 4.3 Orotate phosphoribosyltransferase (EC 2.4.2.10) compare
GFF207 +1.3 4.5 Nucleoside ABC transporter, permease protein 2 compare
GFF3062 +1.3 4.3 Chromosome initiation inhibitor compare
GFF4851 +1.3 3.8 Xanthine-guanine phosphoribosyltransferase (EC 2.4.2.22) compare
GFF1622 +1.3 1.3 Trehalose-6-phosphate phosphatase (EC 3.1.3.12) compare
GFF4040 +1.3 7.5 Cell division trigger factor (EC 5.2.1.8) compare
GFF3339 +1.3 9.6 RNA polymerase sigma factor RpoE compare
GFF1443 +1.3 2.2 Flagellin protein FlaA compare
GFF1497 +1.3 1.0 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) compare
GFF3449 +1.3 2.5 Conjugative transfer protein TrbJ compare
GFF4815 +1.2 1.4 FOG: EAL domain compare
GFF1741 +1.2 10.5 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) compare
GFF1523 +1.2 1.8 decarboxylase compare
GFF209 +1.2 2.9 Hypothetical protein with Rieske (2Fe-2S) region compare
GFF1973 +1.2 10.6 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
GFF43 +1.2 3.1 Glycosyl transferase, group 1 compare
GFF3527 +1.2 5.5 Cyanophycin synthase (EC 6.3.2.29)(EC 6.3.2.30) compare
GFF1171 +1.2 2.2 hypothetical protein compare
GFF2468 +1.2 3.2 Guanine-specific ribonuclease N1 and T1 precursor compare
GFF5435 +1.2 1.4 ABC-type tungstate transport system, ATP-binding protein compare
GFF4847 +1.2 1.2 Arylesterase precursor (EC 3.1.1.2) compare
GFF2210 +1.2 2.4 Hydrogenase transcriptional regulatory protein HoxA compare
GFF1970 +1.2 8.2 Universal stress family protein compare
GFF1544 +1.2 5.7 Transcriptional regulatory protein compare
GFF484 +1.2 1.4 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2) compare
GFF1088 +1.2 2.5 hypothetical protein compare
GFF5735 +1.2 5.3 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
GFF1976 +1.2 1.7 Transcriptional regulator compare
GFF1319 +1.2 4.5 ABC-type multidrug transport system, ATPase component compare
GFF2299 +1.2 4.4 hypothetical protein compare
GFF1169 +1.2 2.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
GFF1962 +1.2 5.1 Threonine dehydratase (EC 4.3.1.19) compare
GFF4893 +1.2 2.6 Nitrogen regulation protein NR(I) compare
GFF915 +1.2 1.6 Enoyl-CoA hydratase (EC 4.2.1.17) compare
GFF4944 +1.2 9.5 transcriptional regulator, TetR family compare
GFF4599 +1.2 2.6 RNA polymerase sigma-70 factor, ECF subfamily compare
GFF4234 +1.2 4.0 Phosphate transport system regulatory protein PhoU compare
GFF768 +1.2 5.5 Peptide chain release factor 3 compare
GFF4759 +1.2 8.9 Polysaccharide biosynthesis protein compare
GFF5074 +1.2 1.3 hypothetical protein compare
GFF1492 +1.2 3.3 FIG00771309: hypothetical protein compare
GFF114 +1.1 8.4 COG0613, Predicted metal-dependent phosphoesterases (PHP family) compare
GFF3487 +1.1 1.6 hypothetical protein compare
GFF722 +1.1 4.8 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
GFF2926 +1.1 9.6 L-carnitine dehydratase/bile acid-inducible protein F compare
GFF80 +1.1 1.8 MotA/TolQ/ExbB proton channel family protein compare
GFF3998 +1.1 1.4 Cobyric acid synthase (EC 6.3.5.10) compare
GFF1283 +1.1 4.1 FIG002842: hypothetical protein compare
GFF2240 +1.1 1.5 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) compare
GFF1956 +1.1 2.2 Inner membrane protein YqiK compare
GFF2658 +1.1 6.2 Na(+) H(+) antiporter subunit A; Na(+) H(+) antiporter subunit B compare
GFF40 +1.1 1.6 hypothetical protein compare
GFF394 +1.1 3.8 transcriptional regulator, LuxR family compare
GFF3900 +1.1 1.5 hypothetical protein compare
GFF2763 +1.1 2.1 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) compare
GFF1043 +1.1 1.2 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
GFF5320 +1.1 1.3 hypothetical protein compare
GFF5574 +1.1 4.5 TRAP dicarboxylate transporter, DctQ subunit, unknown substrate 6 compare
GFF2899 +1.1 6.0 probable bifunctional hydroxylase/oxidoreductase compare
GFF1613 +1.1 1.6 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
GFF4564 +1.1 5.7 Methionine aminopeptidase (EC 3.4.11.18) compare
GFF5790 +1.1 1.2 tRNA-Leu-TAG compare
GFF5602 +1.1 1.4 Inositol transport system sugar-binding protein compare
GFF482 +1.1 1.5 Enoyl-CoA hydratase (EC 4.2.1.17) compare
GFF199 +1.1 1.1 Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1) compare
GFF550 +1.1 2.0 C4-type zinc finger protein, DksA/TraR family compare
GFF2391 +1.1 1.1 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
GFF5476 +1.1 3.1 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
GFF17 +1.1 1.1 LysR family transcriptional regulator YfeR compare
GFF817 +1.1 4.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare


Specific Phenotypes

For 31 genes in this experiment

For carbon source Ying_all64 in Hydrogenophaga sp. GW460-11-11-14-LB1

For carbon source Ying_all64 across organisms