Experiment set2S238 for Escherichia coli ECRC98

Compare to:

Control_ECRC98_WM

200 most important genes:

  gene name fitness t score description  
JDDGAC_14795 serB -7.2 -5.0 phosphoserine phosphatase compare
JDDGAC_17290 metF -6.8 -11.5 methylenetetrahydrofolate reductase compare
JDDGAC_25755 purM -6.7 -12.1 Phosphoribosylformylglycinamidine cyclo-ligase compare
JDDGAC_24895 -6.7 -1.9 Leader peptide of chorismate mutase-P-prephenate dehydratase compare
JDDGAC_26575 aroC -6.6 -4.5 chorismate synthase compare
JDDGAC_24045 cysH -6.3 -10.3 phosphoadenosine phosphosulfate reductase compare
JDDGAC_28540 rfbE -6.3 -3.1 GDP-perosamine synthase RfbE/PerA compare
JDDGAC_14320 leuC1 -6.2 -17.7 3-isopropylmalate dehydratase large subunit 1 compare
JDDGAC_11490 purK -6.1 -10.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
JDDGAC_17300 metB -6.1 -13.7 cystathionine gamma-synthase compare
JDDGAC_25875 purC -6.1 -7.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
JDDGAC_27740 -6.0 -1.7 regulator compare
JDDGAC_23100 serA -6.0 -13.4 phosphoglycerate dehydrogenase compare
JDDGAC_26675 purF -5.9 -15.4 amidophosphoribosyltransferase compare
JDDGAC_25135 purL -5.7 -21.8 phosphoribosylformylglycinamidine synthase compare
JDDGAC_14315 leuB -5.6 -15.9 3-isopropylmalate dehydrogenase compare
JDDGAC_09100 serC -5.6 -10.0 3-phosphoserine/phosphohydroxythreonine transaminase compare
JDDGAC_25435 guaB -5.6 -3.8 IMP dehydrogenase compare
JDDGAC_10355 acrZ -5.5 -1.6 multidrug efflux pump accessory protein AcrZ compare
JDDGAC_13940 dksA -5.5 -8.8 RNA polymerase-binding protein DksA compare
JDDGAC_16935 purH -5.5 -15.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
JDDGAC_19280 rfaG -5.4 -7.4 Lipopolysaccharide core biosynthesis protein RfaG compare
JDDGAC_20745 aroB -5.4 -5.2 3-dehydroquinate synthase compare
JDDGAC_24035 cysJ -5.3 -12.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit compare
JDDGAC_18265 ilvE -5.0 -13.6 branched-chain-amino-acid transaminase compare
JDDGAC_22595 metC -4.9 -12.1 cystathionine beta-lyase compare
JDDGAC_16900 metA -4.8 -6.2 homoserine O-succinyltransferase compare
JDDGAC_21580 lptC -4.8 -1.6 LPS export ABC transporter periplasmic protein LptC compare
JDDGAC_24115 cysC -4.8 -10.8 Adenylyl-sulfate kinase compare
JDDGAC_09095 aroA -4.8 -13.4 3-phosphoshikimate 1-carboxyvinyltransferase compare
JDDGAC_10575 odhB -4.7 -3.2 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
JDDGAC_09385 lrp -4.7 -5.7 leucine-responsive transcriptional regulator Lrp compare
JDDGAC_15675 cysQ -4.6 -5.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
JDDGAC_28610 hisH -4.4 -4.7 imidazole glycerol phosphate synthase subunit HisH compare
JDDGAC_05200 trpE -4.4 -8.2 anthranilate synthase component I compare
JDDGAC_18245 ilvC -4.3 -15.6 ketol-acid reductoisomerase compare
JDDGAC_24890 pheA -4.3 -9.6 bifunctional chorismate mutase/prephenate dehydratase compare
JDDGAC_15870 purA -4.3 -2.9 adenylosuccinate synthase compare
JDDGAC_05215 trpB -4.2 -6.5 tryptophan synthase subunit beta compare
JDDGAC_10475 tolQ -4.2 -3.4 Tol-Pal system protein TolQ compare
JDDGAC_14325 leuD -4.1 -5.3 3-isopropylmalate dehydratase small subunit compare
JDDGAC_16940 purD -4.1 -7.2 Phosphoribosylamine--glycine ligase compare
JDDGAC_17735 glnG -4.1 -2.6 nitrogen regulation protein NR(I) compare
JDDGAC_18785 -4.0 -1.6 hypothetical protein compare
JDDGAC_25045 rseA -4.0 -5.0 anti-sigma-E factor RseA compare
JDDGAC_14700 thrB -4.0 -6.5 homoserine kinase compare
JDDGAC_18260 ilvD -4.0 -14.4 dihydroxy-acid dehydratase compare
JDDGAC_28605 hisA -3.9 -3.6 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase compare
JDDGAC_05220 trpA -3.8 -3.6 tryptophan synthase subunit alpha compare
JDDGAC_22885 yggS -3.8 -6.2 pyridoxal phosphate homeostasis protein compare
JDDGAC_24040 cysI -3.8 -7.0 assimilatory sulfite reductase (NADPH) hemoprotein subunit compare
JDDGAC_14705 thrA -3.8 -15.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
JDDGAC_09815 mntS -3.6 -2.5 manganase accumulation protein MntS compare
JDDGAC_11485 purE -3.6 -3.2 N5-carboxyaminoimidazole ribonucleotide mutase compare
JDDGAC_05205 trpD -3.6 -5.8 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
JDDGAC_05210 trpCF -3.5 -9.0 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
JDDGAC_14440 apaH -3.5 -2.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
JDDGAC_25750 purN -3.5 -7.3 phosphoribosylglycinamide formyltransferase compare
JDDGAC_25690 -3.5 -2.6 acyltransferase compare
JDDGAC_28620 hisC -3.5 -7.2 histidinol-phosphate transaminase compare
JDDGAC_19305 rfaB -3.4 -6.3 UDP-glucose--(glucosyl)LPS alpha-1,2-glucosyltransferase compare
JDDGAC_18255 ilvA -3.4 -7.3 threonine ammonia-lyase, biosynthetic compare
JDDGAC_28510 -3.4 -11.0 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,o ctacis-undecaprenol 4-epimerase compare
JDDGAC_25440 guaA -3.4 -2.3 glutamine-hydrolyzing GMP synthase compare
JDDGAC_14695 thrC -3.4 -5.5 threonine synthase compare
JDDGAC_11470 cysS -3.3 -1.3 cysteine--tRNA ligase compare
JDDGAC_24885 tyrA -3.3 -13.3 bifunctional chorismate mutase/prephenate dehydrogenase compare
JDDGAC_12265 proC -3.2 -3.9 pyrroline-5-carboxylate reductase compare
JDDGAC_14310 -3.2 -8.7 2-isopropylmalate synthase compare
JDDGAC_21185 aroE -3.2 -5.1 shikimate dehydrogenase compare
JDDGAC_00825 nudB -3.2 -1.2 dihydroneopterin triphosphate diphosphatase compare
JDDGAC_28520 wcaA -3.1 -1.9 glycosyl transferase compare
JDDGAC_05985 galU -3.1 -2.9 UTP--glucose-1-phosphate uridylyltransferase GalU compare
JDDGAC_19320 rfaF -3.0 -2.8 ADP-heptose--LPS heptosyltransferase RfaF compare
JDDGAC_18205 wecA -2.8 -13.7 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase compare
JDDGAC_19310 rfaL -2.8 -7.6 O-antigen ligase RfaL compare
JDDGAC_02140 rsxB -2.8 -2.4 electron transport complex subunit RsxB compare
JDDGAC_10470 tolR -2.7 -4.1 colicin uptake protein TolR compare
JDDGAC_28600 hisF -2.6 -1.4 Imidazole glycerol phosphate synthase subunit HisF compare
JDDGAC_08995 aspC -2.6 -3.4 aspartate transaminase compare
JDDGAC_06700 -2.6 -2.5 DUF4222 domain-containing protein compare
JDDGAC_28575 perB -2.6 -2.5 GDP-perosamine N-acetyltransferase compare
JDDGAC_14710 thrL -2.5 -3.3 thr operon leader peptide compare
JDDGAC_21505 gltD -2.5 -8.5 glutamate synthase subunit GltD compare
JDDGAC_28615 hisB -2.4 -2.3 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB compare
JDDGAC_21510 gltB -2.4 -14.5 glutamate synthase large subunit compare
JDDGAC_04780 ogt -2.4 -1.8 methylated-DNA--[protein]-cysteine S-methyltransferase compare
JDDGAC_25315 hscA -2.3 -1.1 Fe-S protein assembly chaperone HscA compare
JDDGAC_03730 ydeQ -2.3 -1.5 Uncharacterized fimbrial-like protein YdeQ compare
JDDGAC_19290 waaO -2.2 -3.8 lipopolysaccharide 3-alpha-galactosyltransferase compare
JDDGAC_21715 argG -2.2 -6.8 argininosuccinate synthase compare
JDDGAC_29975 sopA -2.2 -3.3 plasmid-partitioning protein SopA compare
JDDGAC_28625 hisD -2.2 -4.8 Histidinol dehydrogenase compare
JDDGAC_28595 hisIE -2.1 -2.9 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
JDDGAC_19765 -2.1 -1.9 Type I toxin-antitoxin system toxin Ldr family protein compare
JDDGAC_17890 rfaH -2.1 -3.3 transcription/translation regulatory transformer protein RfaH compare
JDDGAC_20810 cysG -2.1 -8.5 siroheme synthase CysG compare
JDDGAC_13640 gmhB -2.1 -2.2 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase compare
JDDGAC_19185 rpoZ -2.1 -1.0 DNA-directed RNA polymerase subunit omega compare
JDDGAC_09540 -2.1 -1.1 hypothetical protein compare
JDDGAC_20530 glgA -2.1 -11.4 glycogen synthase GlgA compare
JDDGAC_18250 ilvY -2.0 -6.0 HTH-type transcriptional activator IlvY compare
JDDGAC_25525 -2.0 -2.1 hypothetical protein compare
JDDGAC_10455 pal -2.0 -1.7 peptidoglycan-associated lipoprotein Pal compare
JDDGAC_28845 -2.0 -2.4 hypothetical protein compare
JDDGAC_04725 ynaL -2.0 -1.2 Protein YnaL compare
JDDGAC_17205 -2.0 -5.7 acetylglutamate kinase compare
JDDGAC_17455 pfkA -2.0 -3.0 6-phosphofructokinase compare
JDDGAC_17200 argH -2.0 -7.0 argininosuccinate lyase compare
JDDGAC_18405 mnmG -1.9 -3.7 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
JDDGAC_10810 nagB -1.9 -3.9 glucosamine-6-phosphate deaminase compare
JDDGAC_10465 tolA -1.9 -2.1 cell envelope integrity protein TolA compare
JDDGAC_28630 hisG -1.9 -4.1 ATP phosphoribosyltransferase compare
JDDGAC_10460 tolB -1.9 -4.8 Tol-Pal system protein TolB compare
JDDGAC_26150 cysK -1.8 -7.9 cysteine synthase A compare
JDDGAC_03315 -1.8 -1.4 hypothetical protein compare
JDDGAC_11985 clpX -1.8 -2.9 ATP-dependent protease ATP-binding subunit ClpX compare
JDDGAC_14540 carA -1.8 -6.9 carbamoyl phosphate synthase small subunit compare
JDDGAC_06145 prs -1.7 -1.8 ribose-phosphate diphosphokinase compare
JDDGAC_14535 carB -1.7 -8.6 carbamoyl-phosphate synthase large subunit compare
JDDGAC_14435 apaG -1.6 -1.8 Co2+/Mg2+ efflux protein ApaG compare
JDDGAC_04410 -1.6 -1.3 Tail completion protein Z compare
JDDGAC_09390 trxB -1.6 -1.5 thioredoxin-disulfide reductase compare
JDDGAC_00795 cmoB -1.6 -2.7 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
JDDGAC_15475 argF -1.6 -6.9 ornithine carbamoyltransferase compare
JDDGAC_23140 ygfB -1.6 -1.5 UPF0149 family protein YgfB compare
JDDGAC_30180 repA2 -1.6 -4.9 Replication regulatory protein repA2 compare
JDDGAC_06135 lolB -1.6 -1.6 lipoprotein insertase outer membrane protein LolB compare
JDDGAC_15525 mgtL -1.6 -1.4 mgtA leader peptide compare
JDDGAC_27410 psuK -1.5 -1.0 pseudouridine kinase compare
JDDGAC_01680 btuE -1.5 -2.3 bifunctional thioredoxin/glutathione peroxidase compare
JDDGAC_07155 ndh -1.5 -2.5 NADH-quinone dehydrogenase compare
JDDGAC_04365 -1.5 -1.2 Putative phage tail component compare
JDDGAC_28525 wzy -1.5 -2.1 O157 family O-antigen polymerase compare
JDDGAC_13950 pcnB -1.5 -2.5 polynucleotide adenylyltransferase PcnB compare
JDDGAC_17730 glnL -1.5 -2.0 nitrogen regulation protein NR(II) compare
JDDGAC_28590 wzzB -1.5 -7.2 LPS O-antigen chain length determinant protein WzzB compare
JDDGAC_11035 lipB -1.5 -1.1 lipoyl(octanoyl) transferase LipB compare
JDDGAC_03630 yneG -1.4 -1.5 Uncharacterized protein YneG compare
JDDGAC_01600 yniA -1.4 -1.2 putative ketoamine kinase YniA compare
JDDGAC_10815 nagA -1.4 -3.0 N-acetylglucosamine-6-phosphate deacetylase compare
JDDGAC_03940 nhoA -1.4 -3.1 N-hydroxyarylamine O-acetyltransferase compare
JDDGAC_11990 clpP -1.4 -2.3 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
JDDGAC_17210 argC -1.4 -5.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
JDDGAC_17715 typA -1.4 -6.2 ribosome-dependent GTPase TypA compare
JDDGAC_00935 yebF -1.4 -1.1 Protein YebF compare
JDDGAC_01585 ybcI -1.3 -2.7 metal-dependent hydrolase compare
JDDGAC_28175 -1.3 -1.2 transcription factor compare
JDDGAC_09995 moaC -1.3 -2.1 cyclic pyranopterin monophosphate synthase MoaC compare
JDDGAC_18035 uvrD -1.3 -5.2 DNA helicase II compare
JDDGAC_14455 -1.3 -2.0 Dihydrofolate reductase compare
JDDGAC_20115 hicB -1.3 -2.3 toxin-antitoxin system HicB family antitoxin compare
JDDGAC_25415 bamB -1.3 -2.7 outer membrane protein assembly factor BamB compare
JDDGAC_01035 proQ -1.3 -4.2 RNA chaperone ProQ compare
JDDGAC_06275 ycgL -1.3 -1.5 Protein YcgL compare
JDDGAC_05625 -1.3 -2.1 Bacteriophage Mu, Gp27 compare
JDDGAC_18275 ilvG -1.3 -7.7 acetolactate synthase 2 catalytic subunit compare
JDDGAC_27240 ccmA -1.3 -2.5 cytochrome c biogenesis heme-transporting ATPase CcmA compare
JDDGAC_06515 -1.2 -1.1 DUF1398 domain-containing protein compare
JDDGAC_25480 -1.2 -2.1 hypothetical protein compare
JDDGAC_05250 nleG -1.2 -1.2 T3SS effector E3 ubiquitin-protein ligase NleG compare
JDDGAC_02135 rsxC -1.2 -4.0 electron transport complex subunit RsxC compare
JDDGAC_06345 tfaX -1.2 -1.5 Protein TfaX compare
JDDGAC_06565 ybcN -1.2 -1.0 Uncharacterized protein YbcN compare
JDDGAC_23435 -1.2 -1.9 EscS/YscS/HrcS family type III secretion system export apparatus protein compare
JDDGAC_29105 -1.2 -1.1 tail assembly protein compare
JDDGAC_13120 -1.2 -1.1 DUF2635 domain-containing protein compare
JDDGAC_07690 -1.2 -1.9 IS150 conserved protein InsB compare
JDDGAC_10110 -1.2 -1.5 phage minor tail protein L compare
JDDGAC_19300 rfaJ -1.2 -1.9 glucosyltransferase compare
JDDGAC_15075 yjiL -1.2 -2.3 Uncharacterized protein YjiL compare
JDDGAC_17910 tatA -1.2 -0.9 Sec-independent protein translocase subunit TatA compare
JDDGAC_16555 tyrB -1.2 -5.2 aromatic amino acid transaminase compare
JDDGAC_11280 hokE -1.2 -1.5 type I toxin-antitoxin system toxin HokE compare
JDDGAC_04635 -1.2 -1.8 Putative bacterial toxin ydaT compare
JDDGAC_18215 trxA -1.2 -1.4 thioredoxin TrxA compare
JDDGAC_05950 -1.2 -1.2 hypothetical protein compare
JDDGAC_11350 cusR -1.2 -1.2 copper response regulator transcription factor CusR compare
JDDGAC_02120 rsxE -1.1 -3.9 electron transport complex subunit RsxE compare
JDDGAC_11265 fes -1.1 -2.1 enterobactin/ferric enterobactin esterase compare
JDDGAC_06305 minE -1.1 -0.8 cell division topological specificity factor MinE compare
JDDGAC_07710 -1.1 -2.4 General stress protein 16U compare
JDDGAC_01415 gdhA -1.1 -3.0 NADP-specific glutamate dehydrogenase compare
JDDGAC_17215 argE -1.1 -6.6 acetylornithine deacetylase compare
JDDGAC_06310 -1.1 -1.3 autotransporter outer membrane beta-barrel domain-containing protein compare
JDDGAC_18270 -1.1 -3.2 Acetolactate synthase isozyme 2 small subunit compare
JDDGAC_13295 proA -1.1 -4.3 glutamate-5-semialdehyde dehydrogenase compare
JDDGAC_03230 -1.1 -1.0 Ead/Ea22-like protein compare
JDDGAC_17360 hslV -1.1 -1.6 ATP-dependent protease subunit HslV compare
JDDGAC_23460 -1.1 -1.1 Type III secretion protein EprH compare
JDDGAC_26670 cvpA -1.1 -1.5 colicin V production protein compare
JDDGAC_29995 -1.1 -1.0 hypothetical protein compare
JDDGAC_25585 -1.1 -2.1 hypothetical protein compare
JDDGAC_25595 -1.1 -2.6 Phage protein compare
JDDGAC_25660 -1.1 -2.9 hypothetical protein compare
JDDGAC_24995 trxC -1.0 -2.0 thioredoxin TrxC compare
JDDGAC_18660 yidB -1.0 -2.1 Uncharacterized protein YidB compare
JDDGAC_00970 holE -1.0 -1.0 DNA polymerase III subunit theta compare
JDDGAC_01765 ydiF -1.0 -2.6 Acetate CoA-transferase YdiF compare
JDDGAC_26485 Arg_trna -1.0 -2.0 tRNA-Arg(cct) compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in no phage control experiments

For no phage control No phage across organisms