Experiment set2S214 for Escherichia coli ECRC98

Compare to:

WM_TP12

200 most important genes:

  gene name fitness t score description  
JDDGAC_28510 -8.1 -5.6 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,o ctacis-undecaprenol 4-epimerase compare
JDDGAC_19300 rfaJ -8.0 -5.5 glucosyltransferase compare
JDDGAC_19310 rfaL -7.5 -5.2 O-antigen ligase RfaL compare
JDDGAC_28575 perB -7.4 -4.8 GDP-perosamine N-acetyltransferase compare
JDDGAC_28540 rfbE -6.5 -3.0 GDP-perosamine synthase RfbE/PerA compare
JDDGAC_28525 wzy -6.3 -3.2 O157 family O-antigen polymerase compare
JDDGAC_18205 wecA -6.3 -17.4 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase compare
JDDGAC_19290 waaO -6.0 -6.2 lipopolysaccharide 3-alpha-galactosyltransferase compare
JDDGAC_25875 purC -5.8 -5.2 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
JDDGAC_17890 rfaH -5.7 -3.8 transcription/translation regulatory transformer protein RfaH compare
JDDGAC_25435 guaB -5.5 -6.5 IMP dehydrogenase compare
JDDGAC_16935 purH -5.3 -16.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
JDDGAC_25755 purM -5.2 -9.6 Phosphoribosylformylglycinamidine cyclo-ligase compare
JDDGAC_28520 wcaA -5.2 -2.0 glycosyl transferase compare
JDDGAC_18185 rffG -5.1 -12.5 dTDP-glucose 4,6-dehydratase compare
JDDGAC_28590 wzzB -5.0 -9.7 LPS O-antigen chain length determinant protein WzzB compare
JDDGAC_21455 sspA -5.0 -7.4 stringent starvation protein A compare
JDDGAC_19305 rfaB -5.0 -6.4 UDP-glucose--(glucosyl)LPS alpha-1,2-glucosyltransferase compare
JDDGAC_21580 lptC -4.9 -1.6 LPS export ABC transporter periplasmic protein LptC compare
JDDGAC_19280 rfaG -4.8 -12.4 Lipopolysaccharide core biosynthesis protein RfaG compare
JDDGAC_11485 purE -4.8 -4.8 N5-carboxyaminoimidazole ribonucleotide mutase compare
JDDGAC_26675 purF -4.8 -10.0 amidophosphoribosyltransferase compare
JDDGAC_28560 wbdQ -4.6 -2.1 GDP-mannose mannosyl hydrolase WbdQ/WbhG compare
JDDGAC_18180 rfbA -4.6 -9.0 glucose-1-phosphate thymidylyltransferase RfbA compare
JDDGAC_25135 purL -4.5 -17.4 phosphoribosylformylglycinamidine synthase compare
JDDGAC_25750 purN -4.5 -8.5 phosphoribosylglycinamide formyltransferase compare
JDDGAC_15870 purA -4.4 -3.0 adenylosuccinate synthase compare
JDDGAC_14795 serB -4.4 -6.4 phosphoserine phosphatase compare
JDDGAC_15900 miaA -4.1 -2.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
JDDGAC_19320 rfaF -4.0 -2.6 ADP-heptose--LPS heptosyltransferase RfaF compare
JDDGAC_27740 -3.8 -1.8 regulator compare
JDDGAC_25690 -3.8 -2.7 acyltransferase compare
JDDGAC_14075 acnB -3.7 -3.0 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
JDDGAC_16940 purD -3.7 -7.5 Phosphoribosylamine--glycine ligase compare
JDDGAC_26635 -3.7 -9.9 Protein DedA compare
JDDGAC_14440 apaH -3.7 -2.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
JDDGAC_11470 cysS -3.7 -1.4 cysteine--tRNA ligase compare
JDDGAC_22885 yggS -3.6 -5.1 pyridoxal phosphate homeostasis protein compare
JDDGAC_18175 rffC -3.6 -4.9 dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase compare
JDDGAC_25440 guaA -3.5 -2.4 glutamine-hydrolyzing GMP synthase compare
JDDGAC_17735 glnG -3.5 -2.9 nitrogen regulation protein NR(I) compare
JDDGAC_24045 cysH -3.4 -9.7 phosphoadenosine phosphosulfate reductase compare
JDDGAC_10465 tolA -3.4 -3.1 cell envelope integrity protein TolA compare
JDDGAC_09385 lrp -3.3 -4.3 leucine-responsive transcriptional regulator Lrp compare
JDDGAC_09100 serC -3.3 -7.4 3-phosphoserine/phosphohydroxythreonine transaminase compare
JDDGAC_15675 cysQ -3.3 -6.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
JDDGAC_05985 galU -3.3 -3.0 UTP--glucose-1-phosphate uridylyltransferase GalU compare
JDDGAC_23100 serA -3.1 -8.3 phosphoglycerate dehydrogenase compare
JDDGAC_11490 purK -3.0 -7.9 5-(carboxyamino)imidazole ribonucleotide synthase compare
JDDGAC_20745 aroB -3.0 -5.0 3-dehydroquinate synthase compare
JDDGAC_19285 rfaP -2.9 -5.7 lipopolysaccharide core heptose(I) kinase RfaP compare
JDDGAC_13940 dksA -2.9 -5.9 RNA polymerase-binding protein DksA compare
JDDGAC_06700 -2.7 -2.7 DUF4222 domain-containing protein compare
JDDGAC_29980 sopA -2.7 -1.3 plasmid-partitioning protein SopA compare
JDDGAC_24115 cysC -2.7 -9.7 Adenylyl-sulfate kinase compare
JDDGAC_07280 rne -2.6 -3.4 ribonuclease E compare
JDDGAC_26945 arnD -2.5 -4.0 4-deoxy-4-formamido-L-arabinose-phosphoundecapren ol deformylase compare
JDDGAC_26670 cvpA -2.5 -3.8 colicin V production protein compare
JDDGAC_17715 typA -2.5 -9.8 ribosome-dependent GTPase TypA compare
JDDGAC_24035 cysJ -2.4 -9.3 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit compare
JDDGAC_18405 mnmG -2.4 -5.0 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
JDDGAC_25045 rseA -2.4 -2.1 anti-sigma-E factor RseA compare
JDDGAC_06265 ycgN -2.3 -1.8 YcgN family cysteine cluster protein compare
JDDGAC_18170 rffA -2.2 -4.8 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
JDDGAC_07825 -2.2 -1.1 Membrane protein compare
JDDGAC_14420 surA -2.1 -2.8 peptidylprolyl isomerase SurA compare
JDDGAC_10815 nagA -2.1 -3.3 N-acetylglucosamine-6-phosphate deacetylase compare
JDDGAC_24040 cysI -2.1 -6.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit compare
JDDGAC_10475 tolQ -2.1 -3.4 Tol-Pal system protein TolQ compare
JDDGAC_07480 -2.1 -1.9 Uncharacterized protein YmdA compare
JDDGAC_13950 pcnB -2.0 -4.8 polynucleotide adenylyltransferase PcnB compare
JDDGAC_18160 rffT -2.0 -5.3 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase compare
JDDGAC_04130 ydcH -2.0 -1.4 Uncharacterized protein YdcH compare
JDDGAC_26575 aroC -2.0 -3.3 chorismate synthase compare
JDDGAC_10455 pal -1.9 -2.4 peptidoglycan-associated lipoprotein Pal compare
JDDGAC_21185 aroE -1.9 -5.0 shikimate dehydrogenase compare
JDDGAC_22880 yggT -1.9 -1.5 osmotic shock tolerance protein YggT compare
JDDGAC_16800 pgi -1.8 -6.0 glucose-6-phosphate isomerase compare
JDDGAC_00350 fliT -1.8 -2.7 flagella biosynthesis regulatory protein FliT compare
JDDGAC_16385 ytcA -1.7 -1.2 Uncharacterized protein YtcA compare
JDDGAC_10355 acrZ -1.7 -1.3 multidrug efflux pump accessory protein AcrZ compare
JDDGAC_00825 nudB -1.7 -1.3 dihydroneopterin triphosphate diphosphatase compare
JDDGAC_21765 pnp -1.7 -4.5 polyribonucleotide nucleotidyltransferase compare
JDDGAC_12265 proC -1.7 -2.6 pyrroline-5-carboxylate reductase compare
JDDGAC_13050 -1.7 -1.4 phage tail protein compare
JDDGAC_10470 tolR -1.7 -1.9 colicin uptake protein TolR compare
JDDGAC_28515 galF -1.6 -3.4 UTP--glucose-1-phosphate uridylyltransferase GalF compare
JDDGAC_11990 clpP -1.6 -2.5 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
JDDGAC_25415 bamB -1.6 -3.7 outer membrane protein assembly factor BamB compare
JDDGAC_09095 aroA -1.6 -6.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
JDDGAC_05250 nleG -1.5 -1.5 T3SS effector E3 ubiquitin-protein ligase NleG compare
JDDGAC_14695 thrC -1.5 -5.1 threonine synthase compare
JDDGAC_00920 kdgA -1.5 -1.6 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase compare
JDDGAC_28760 kil -1.5 -1.5 Protein kil compare
JDDGAC_20740 aroK -1.5 -1.6 shikimate kinase AroK compare
JDDGAC_05215 trpB -1.5 -4.4 tryptophan synthase subunit beta compare
JDDGAC_14710 thrL -1.4 -3.1 thr operon leader peptide compare
JDDGAC_12460 lacI -1.4 -5.5 DNA-binding transcriptional repressor LacI compare
JDDGAC_09505 ybjQ -1.4 -3.4 UPF0145 protein YbjQ compare
JDDGAC_18215 trxA -1.4 -1.0 thioredoxin TrxA compare
JDDGAC_26570 prmB -1.4 -5.6 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
JDDGAC_09810 mntR -1.4 -2.2 manganese-binding transcriptional regulator MntR compare
JDDGAC_14700 thrB -1.4 -5.6 homoserine kinase compare
JDDGAC_07260 yceD -1.4 -2.1 23S rRNA accumulation protein YceD compare
JDDGAC_13890 -1.4 -1.5 Protein YadX compare
JDDGAC_14705 thrA -1.3 -8.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
JDDGAC_30180 repA2 -1.3 -4.3 Replication regulatory protein repA2 compare
JDDGAC_01035 proQ -1.3 -3.4 RNA chaperone ProQ compare
JDDGAC_06690 -1.3 -2.5 hypothetical protein compare
JDDGAC_24675 -1.3 -1.1 hypothetical protein compare
JDDGAC_28800 -1.3 -1.5 XRE family transcriptional regulator compare
JDDGAC_22440 tolC -1.3 -5.0 outer membrane channel protein TolC compare
JDDGAC_03335 -1.3 -1.4 9-O-acetyl-N-acetylneuraminic acid deacetylase compare
JDDGAC_18600 -1.3 -1.4 hypothetical protein compare
JDDGAC_08380 appA -1.3 -3.5 bifunctional acid phosphatase/4-phytase compare
JDDGAC_29975 sopA -1.3 -2.3 plasmid-partitioning protein SopA compare
JDDGAC_28935 -1.2 -1.7 sialate O-acetylesterase compare
JDDGAC_13000 -1.2 -1.4 AAA family ATPase compare
JDDGAC_20930 yheO -1.2 -1.1 Uncharacterized protein YheO compare
JDDGAC_28610 hisH -1.2 -2.6 imidazole glycerol phosphate synthase subunit HisH compare
JDDGAC_22945 speB -1.2 -3.5 agmatinase compare
JDDGAC_21125 yhdN -1.2 -2.1 Uncharacterized protein YhdN compare
JDDGAC_10460 tolB -1.2 -2.9 Tol-Pal system protein TolB compare
JDDGAC_23420 -1.2 -1.5 type III secretion protein compare
JDDGAC_10390 gpmA -1.2 -3.2 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
JDDGAC_10810 nagB -1.2 -2.7 glucosamine-6-phosphate deaminase compare
JDDGAC_19100 -1.2 -0.9 Aec79 compare
JDDGAC_02140 rsxB -1.2 -1.4 electron transport complex subunit RsxB compare
JDDGAC_24340 srlB -1.1 -1.4 PTS glucitol/sorbitol transporter subunit IIA compare
JDDGAC_27410 psuK -1.1 -0.9 pseudouridine kinase compare
JDDGAC_03280 -1.1 -1.4 hypothetical protein compare
JDDGAC_05205 trpD -1.1 -4.0 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
JDDGAC_11975 -1.1 -1.5 Lon protease compare
JDDGAC_07330 flgC -1.1 -2.3 flagellar basal body rod protein FlgC compare
JDDGAC_09325 pflA -1.1 -2.1 pyruvate formate lyase 1-activating protein compare
JDDGAC_08295 cbpM -1.1 -0.9 chaperone modulator CbpM compare
JDDGAC_28450 wcaF -1.1 -2.3 colanic acid biosynthesis acetyltransferase WcaF compare
JDDGAC_21770 nlpI -1.1 -6.1 lipoprotein NlpI compare
JDDGAC_24630 xerD -1.1 -1.4 site-specific integrase compare
JDDGAC_13125 -1.1 -2.5 Putative bacteriophage protein compare
JDDGAC_20355 -1.1 -1.8 DUF1778 domain-containing protein compare
JDDGAC_10540 -1.0 -1.1 DUF4387 domain-containing protein compare
JDDGAC_10750 pgm -1.0 -5.4 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) compare
JDDGAC_03995 yncG -1.0 -1.6 Uncharacterized GST-like protein YncG compare
JDDGAC_11835 rsmS -1.0 -1.0 pleiotropic regulatory protein RsmS compare
JDDGAC_07690 -1.0 -1.9 IS150 conserved protein InsB compare
JDDGAC_00460 -1.0 -1.6 phage tail protein compare
JDDGAC_23240 yqfH -1.0 -1.2 Protein YqfH compare
JDDGAC_18395 asnC -1.0 -5.9 transcriptional regulator AsnC compare
JDDGAC_01220 yoaG -1.0 -1.1 Protein YoaG compare
JDDGAC_13175 rzpD -1.0 -1.0 prophage endopeptidase RzpD compare
JDDGAC_06645 -1.0 -1.6 hypothetical protein compare
JDDGAC_30200 putA1 -1.0 -1.5 CopG family transcriptional regulator compare
JDDGAC_06515 -1.0 -1.3 DUF1398 domain-containing protein compare
JDDGAC_14430 rsmA -1.0 -1.2 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA compare
JDDGAC_28855 -1.0 -2.0 recombination protein NinB compare
JDDGAC_05210 trpCF -1.0 -4.2 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
JDDGAC_12140 parD -1.0 -1.5 Antitoxin ParD compare
JDDGAC_10575 odhB -1.0 -2.1 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
JDDGAC_27785 rusA -1.0 -0.7 crossover junction endodeoxyribonuclease RusA compare
JDDGAC_19275 rfaQ -1.0 -3.2 lipopolysaccharide core heptosyltransferase RfaQ compare
JDDGAC_23425 fliN -0.9 -0.7 YscQ/HrcQ family type III secretion apparatus protein compare
JDDGAC_10275 -0.9 -1.0 DUF1382 domain-containing protein compare
JDDGAC_28685 -0.9 -1.4 AlpA family transcriptional regulator compare
JDDGAC_24885 tyrA -0.9 -5.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
JDDGAC_13240 ymfM -0.9 -1.6 Uncharacterized protein YmfM compare
JDDGAC_03925 narI -0.9 -2.1 respiratory nitrate reductase subunit gamma compare
JDDGAC_14450 -0.9 -1.4 antitoxin compare
JDDGAC_01040 prc -0.9 -4.0 carboxy terminal-processing peptidase compare
JDDGAC_18590 tnaC -0.9 -1.3 tryptophanase leader peptide compare
JDDGAC_29130 -0.9 -2.1 secretion protein EspS compare
JDDGAC_07090 potC -0.9 -1.8 spermidine/putrescine ABC transporter permease PotC compare
JDDGAC_14890 holD -0.9 -0.6 DNA polymerase III subunit psi compare
JDDGAC_07860 ureF -0.9 -3.5 Urease accessory protein UreF compare
JDDGAC_27870 -0.9 -1.2 terminase compare
JDDGAC_18020 corA -0.9 -1.6 magnesium/cobalt transporter CorA compare
JDDGAC_20810 cysG -0.9 -5.2 siroheme synthase CysG compare
JDDGAC_21510 gltB -0.9 -7.1 glutamate synthase large subunit compare
JDDGAC_07640 -0.9 -1.0 DNA-binding protein compare
JDDGAC_19185 rpoZ -0.9 -0.6 DNA-directed RNA polymerase subunit omega compare
JDDGAC_26485 Arg_trna -0.9 -1.6 tRNA-Arg(cct) compare
JDDGAC_28890 -0.9 -1.1 Serine/threonine-protein phosphatase compare
JDDGAC_05740 -0.9 -0.8 phage tail protein compare
JDDGAC_06415 -0.9 -0.8 tail assembly protein compare
JDDGAC_20435 -0.8 -1.2 hypothetical protein compare
JDDGAC_23565 -0.8 -0.6 hypothetical protein compare
JDDGAC_00595 -0.8 -0.9 DUF2511 domain-containing protein compare
JDDGAC_08945 elfA -0.8 -1.5 Fimbrial subunit ElfA compare
JDDGAC_03670 lsrC -0.8 -1.0 autoinducer 2 ABC transporter permease LsrC compare
JDDGAC_02155 ydgT -0.8 -1.8 transcription modulator YdgT compare
JDDGAC_21715 argG -0.8 -3.7 argininosuccinate synthase compare
JDDGAC_11260 ybdZ -0.8 -0.7 Enterobactin biosynthesis protein YbdZ compare
JDDGAC_17455 pfkA -0.8 -1.4 6-phosphofructokinase compare
JDDGAC_06185 emtA -0.8 -2.2 membrane-bound lytic murein transglycosylase EmtA compare
JDDGAC_25580 Arg_trna -0.8 -1.7 tRNA-Arg(tct) compare
JDDGAC_25290 iscR -0.8 -3.0 Fe-S cluster assembly transcriptional regulator IscR compare
JDDGAC_00375 fliZ -0.8 -1.6 flagella biosynthesis regulatory protein FliZ compare
JDDGAC_15570 yjgA -0.8 -3.6 ribosome-associated protein compare
JDDGAC_13320 gpt -0.8 -1.8 xanthine phosphoribosyltransferase compare
JDDGAC_29155 yeeX -0.8 -1.4 DUF496 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in phage experiments

For phage Phage across organisms