Experiment set2S190 for Escherichia coli ECOR38

Compare to:

Control_ECOR38

200 most detrimental genes:

  gene name fitness t score description  
HEPCGN_12910 tatB +1.6 3.0 Sec-independent protein translocase protein TatB compare
HEPCGN_12790 +1.4 2.0 hypothetical protein compare
HEPCGN_04675 ruvC +1.4 2.1 crossover junction endodeoxyribonuclease RuvC compare
HEPCGN_02135 +1.2 1.8 hypothetical protein compare
HEPCGN_11880 +1.2 1.7 hypothetical protein compare
HEPCGN_04865 prc +1.2 7.2 carboxy terminal-processing peptidase compare
HEPCGN_26960 +1.2 1.7 Putative DNA-invertase compare
HEPCGN_02975 dcd +1.2 2.0 dCTP deaminase compare
HEPCGN_20525 rseA +1.1 2.6 anti-sigma-E factor RseA compare
HEPCGN_25175 +1.0 1.5 DUF1482 domain-containing protein compare
HEPCGN_02400 +1.0 1.7 hypothetical protein compare
HEPCGN_24100 +1.0 2.2 host cell division inhibitor Icd-like protein compare
HEPCGN_25225 dnaC +1.0 3.1 DNA replication protein DnaC compare
HEPCGN_02900 +0.9 1.1 Type I toxin-antitoxin system Ibs family toxin compare
HEPCGN_14240 +0.9 2.1 IS3 family transposase compare
HEPCGN_26845 marA +0.9 3.5 MDR efflux pump AcrAB transcriptional activator MarA compare
HEPCGN_26445 bdm +0.9 1.5 biofilm-dependent modulation protein compare
HEPCGN_00950 ybeL +0.8 3.1 zinc ribbon-containing protein compare
HEPCGN_19250 ygdT +0.8 1.6 Protein YgdT compare
HEPCGN_24440 +0.8 2.0 phage major tail tube protein compare
HEPCGN_04310 +0.8 1.6 phage tail protein compare
HEPCGN_10145 fbp +0.8 5.8 class 1 fructose-bisphosphatase compare
HEPCGN_11980 hupA +0.8 3.2 DNA-binding protein HU-alpha compare
HEPCGN_02810 gatB +0.8 1.5 PTS galactitol transporter subunit IIB compare
HEPCGN_08550 yacG +0.8 0.9 DNA gyrase inhibitor YacG compare
HEPCGN_26815 xerD +0.8 0.9 integrase compare
HEPCGN_26450 osmC +0.8 1.8 peroxiredoxin OsmC compare
HEPCGN_26535 ydeM +0.7 2.9 anaerobic sulfatase maturase compare
HEPCGN_16885 sfsB +0.7 1.5 DNA-binding transcriptional regulator SfsB compare
HEPCGN_05295 spy +0.7 1.6 ATP-independent periplasmic protein-refolding chaperone Spy compare
HEPCGN_25400 +0.7 1.6 DNA-packaging protein FI compare
HEPCGN_06015 manA +0.7 1.6 mannose-6-phosphate isomerase compare
HEPCGN_25495 +0.7 1.4 DNA-damage-inducible protein DinI compare
HEPCGN_26185 rimL +0.7 1.8 50S ribosomal protein L7/L12-serine acetyltransferase compare
HEPCGN_24160 +0.7 1.5 phage head closure protein compare
HEPCGN_18110 neuD +0.7 2.2 NeuD protein involved in sialic acid synthesis compare
HEPCGN_03685 +0.7 2.8 SMEK domain-containing protein compare
HEPCGN_03020 wcaB +0.7 1.3 colanic acid biosynthesis acetyltransferase WcaB compare
HEPCGN_26850 marB +0.7 1.5 multiple antibiotic resistance protein MarB compare
HEPCGN_08710 leuD +0.7 2.5 3-isopropylmalate dehydratase small subunit compare
HEPCGN_02475 +0.6 1.4 SAR-endolysin compare
HEPCGN_20205 ygaM +0.6 1.8 Uncharacterized protein YgaM compare
HEPCGN_26595 lsrC +0.6 3.4 autoinducer 2 ABC transporter permease LsrC compare
HEPCGN_23470 +0.6 1.2 YccE family protein compare
HEPCGN_07790 crl +0.6 3.0 sigma factor-binding protein Crl compare
HEPCGN_04385 marR +0.6 0.9 MarR family transcriptional regulator compare
HEPCGN_20055 +0.6 1.4 hypothetical protein compare
HEPCGN_23670 +0.6 0.9 Uncharacterized protein YmdA compare
HEPCGN_26060 ynbE +0.6 1.7 YdbH family protein compare
HEPCGN_26820 +0.6 1.7 LysR-substrate domain-containing protein compare
HEPCGN_02855 +0.6 0.8 type II toxin-antitoxin system ParD family antitoxin compare
HEPCGN_05905 +0.6 1.1 hypothetical protein compare
HEPCGN_18930 ygfM +0.6 1.7 Uncharacterized protein YgfM compare
HEPCGN_03425 +0.6 0.9 acetyltransferase compare
HEPCGN_26865 lacF +0.6 1.0 PTS lactose/cellobiose transporter subunit IIA compare
HEPCGN_14635 yibL +0.6 0.9 YibL family ribosome-associated protein compare
HEPCGN_19120 fixB +0.6 1.3 electron transfer flavoprotein compare
HEPCGN_01945 gsiD +0.6 2.0 glutathione ABC transporter permease GsiD compare
HEPCGN_11190 adiY +0.5 1.5 DNA-binding transcriptional activator AdiY compare
HEPCGN_05865 slyB +0.5 1.5 outer membrane lipoprotein SlyB compare
HEPCGN_24000 comR +0.5 2.0 TetR family copper-responsive transcriptional repressor ComR compare
HEPCGN_25010 narJ +0.5 2.7 nitrate reductase molybdenum cofactor assembly chaperone compare
HEPCGN_00850 pagP +0.5 2.4 lipid IV(A) palmitoyltransferase PagP compare
HEPCGN_14930 tag +0.5 1.6 DNA-3-methyladenine glycosylase I compare
HEPCGN_24800 ldcA +0.5 1.0 muramoyltetrapeptide carboxypeptidase compare
HEPCGN_27165 +0.5 1.2 hypothetical protein compare
HEPCGN_10435 yjfJ +0.5 0.9 Uncharacterized protein YjfJ compare
HEPCGN_05720 ydhR +0.5 2.1 monooxygenase compare
HEPCGN_05950 ydgT +0.5 1.4 transcription modulator YdgT compare
HEPCGN_01575 acrZ +0.5 1.3 multidrug efflux pump accessory protein AcrZ compare
HEPCGN_24980 narX +0.5 0.8 nitrate/nitrite two-component system sensor histidine kinase NarX compare
HEPCGN_18390 papF +0.5 2.1 P fimbrial tip protein PapF compare
HEPCGN_02620 +0.5 2.2 Ybl63 compare
HEPCGN_07710 rpmE2-1 +0.5 1.3 type B 50S ribosomal protein L31 compare
HEPCGN_13620 +0.5 1.1 hypothetical protein compare
HEPCGN_26645 glsB +0.5 2.4 glutaminase B compare
HEPCGN_14030 +0.5 2.4 antitoxin compare
HEPCGN_25195 +0.5 2.1 hypothetical protein compare
HEPCGN_07450 cynT +0.5 1.7 carbonic anhydrase CynT compare
HEPCGN_21475 +0.5 1.1 RNA-guided endonuclease TnpB family protein compare
HEPCGN_02565 +0.5 1.3 phage tail protein compare
HEPCGN_26305 yncG +0.5 1.8 Uncharacterized GST-like protein YncG compare
HEPCGN_15895 nudE +0.5 2.1 ADP compounds hydrolase NudE compare
HEPCGN_14370 trmH +0.5 1.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
HEPCGN_23820 flgC +0.5 1.5 flagellar basal body rod protein FlgC compare
HEPCGN_08860 kefF +0.5 1.4 glutathione-regulated potassium-efflux system oxidoreductase KefF compare
HEPCGN_09550 idlP +0.5 1.4 iraD leader peptide compare
HEPCGN_10285 ytfB +0.5 2.2 cell division protein YtfB compare
HEPCGN_21780 +0.5 1.0 Fimbrial domain-containing protein compare
HEPCGN_18040 gspS2 +0.5 1.9 Pilotin AspS 2 compare
HEPCGN_25335 +0.5 1.3 Lysis protein compare
HEPCGN_25240 queH +0.5 2.4 Epoxyqueuosine reductase QueH compare
HEPCGN_17600 +0.5 2.7 Type I toxin-antitoxin system Ibs family toxin compare
HEPCGN_25770 puuC +0.5 2.4 aldehyde dehydrogenase PuuC compare
HEPCGN_04635 cmoA +0.5 2.4 carboxy-S-adenosyl-L-methionine synthase CmoA compare
HEPCGN_26330 +0.5 1.4 hypothetical protein compare
HEPCGN_01860 mntS +0.5 1.5 manganase accumulation protein MntS compare
HEPCGN_11595 plsB +0.5 2.0 glycerol-3-phosphate 1-O-acyltransferase PlsB compare
HEPCGN_07020 yajQ +0.5 1.1 nucleotide binding protein YajQ compare
HEPCGN_11745 +0.4 1.8 Phage tail assembly protein compare
HEPCGN_04630 cmoB +0.4 1.9 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
HEPCGN_04265 +0.4 2.2 baseplate assembly protein compare
HEPCGN_20755 iscR +0.4 2.3 Fe-S cluster assembly transcriptional regulator IscR compare
HEPCGN_05560 +0.4 1.3 hypothetical protein compare
HEPCGN_06160 ynfD +0.4 1.7 Uncharacterized protein YnfD compare
HEPCGN_05555 ydiQ +0.4 1.5 electron transfer flavoprotein compare
HEPCGN_03265 yeeD +0.4 1.3 Putative sulfur carrier protein YeeD compare
HEPCGN_20680 yphD +0.4 1.9 putative ABC transporter permease protein YphD compare
HEPCGN_10905 +0.4 1.8 c-type lysozyme inhibitor compare
HEPCGN_05095 yeaH +0.4 2.0 UPF0229 protein YeaH compare
HEPCGN_03680 +0.4 1.6 DUF977 domain-containing protein compare
HEPCGN_22150 menD +0.4 1.5 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase compare
HEPCGN_11530 +0.4 1.4 hypothetical protein compare
HEPCGN_02715 yehE +0.4 1.4 Uncharacterized protein YehE compare
HEPCGN_08920 caiF +0.4 2.7 carnitine metabolism transcriptional regulator CaiF compare
HEPCGN_25745 +0.4 1.9 DUF2543 domain-containing protein compare
HEPCGN_18335 +0.4 0.9 Transposase ORF B, IS629 compare
HEPCGN_26075 pdxI +0.4 1.6 pyridoxine 4-dehydrogenase compare
HEPCGN_13765 dgoK +0.4 1.9 2-dehydro-3-deoxygalactonokinase compare
HEPCGN_20790 iscX +0.4 1.1 Fe-S cluster assembly protein IscX compare
HEPCGN_24305 bet +0.4 1.7 phage recombination protein Bet compare
HEPCGN_06050 folM +0.4 1.7 dihydromonapterin reductase compare
HEPCGN_18660 fumE +0.4 1.4 fumarase E compare
HEPCGN_24380 +0.4 2.0 phage tail protein compare
HEPCGN_01265 +0.4 1.3 C4-dicarboxylate ABC transporter permease compare
HEPCGN_03770 +0.4 2.1 hypothetical protein compare
HEPCGN_25330 +0.4 1.1 Putative endopeptidase compare
HEPCGN_21785 +0.4 1.6 fimbrial protein compare
HEPCGN_07835 +0.4 1.9 Flagellar system protein compare
HEPCGN_21220 eutJ +0.4 1.4 ethanolamine utilization protein EutJ compare
HEPCGN_22025 yfbR +0.4 2.4 5'-deoxynucleotidase compare
HEPCGN_09310 +0.4 2.1 hypothetical protein compare
HEPCGN_16460 yhdV +0.4 0.7 Uncharacterized protein YhdV compare
HEPCGN_04015 fliR +0.4 0.7 flagellar type III secretion system protein FliR compare
HEPCGN_02090 ybjO +0.4 1.1 Inner membrane protein YbjO compare
HEPCGN_08405 yadI +0.4 2.4 Putative phosphotransferase enzyme IIA component YadI compare
HEPCGN_07095 +0.4 1.9 RNA-guided endonuclease TnpB family protein compare
HEPCGN_12210 oxyR +0.4 2.8 DNA-binding transcriptional regulator OxyR compare
HEPCGN_00205 +0.4 1.7 hypothetical protein compare
HEPCGN_06640 ybbJ +0.4 0.7 Inner membrane protein YbbJ compare
HEPCGN_06330 cspF +0.4 0.6 Cold shock-like protein CspF compare
HEPCGN_06095 ydgU +0.4 0.6 Uncharacterized protein YdgU compare
HEPCGN_11830 fabG +0.4 1.2 sorbitol-6-phosphate 2-dehydrogenase compare
HEPCGN_24685 ycgL +0.4 1.4 Protein YcgL compare
HEPCGN_05490 selO +0.4 1.6 protein adenylyltransferase SelO compare
HEPCGN_24515 +0.4 1.0 Putative lipoprotein compare
HEPCGN_23640 cgsE +0.4 0.9 curli production assembly/transport protein CsgE compare
HEPCGN_03715 +0.4 1.8 DUF968 domain-containing protein compare
HEPCGN_22510 napF +0.4 0.7 ferredoxin-type protein NapF compare
HEPCGN_25995 ynaL +0.4 1.1 Protein YnaL compare
HEPCGN_08870 fixX +0.4 1.9 ferredoxin-like protein FixX compare
HEPCGN_24325 ea10 +0.4 0.7 Protein ea10 compare
HEPCGN_05190 ydjA +0.4 1.3 NAD(P)H nitroreductase compare
HEPCGN_01700 ybhM +0.4 1.3 Uncharacterized protein YbhM compare
HEPCGN_06030 tus +0.4 1.2 DNA replication terminus site-binding protein compare
HEPCGN_10405 yjfN +0.4 1.9 protease activator YjfN compare
HEPCGN_03830 +0.4 1.5 DUF3168 domain-containing protein compare
HEPCGN_23585 +0.4 2.0 hypothetical protein compare
HEPCGN_07600 betI +0.4 1.2 transcriptional regulator BetI compare
HEPCGN_01200 ybgI +0.4 1.1 radiation resistance protein YbgI compare
HEPCGN_17220 +0.4 1.6 YhaC family protein compare
HEPCGN_26615 lsrG +0.4 0.7 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase compare
HEPCGN_17835 exbD +0.4 1.4 TonB system transport protein ExbD compare
HEPCGN_21190 eutQ +0.4 1.5 ethanolamine utilization acetate kinase EutQ compare
HEPCGN_23600 +0.4 1.3 GGDEF domain-containing protein compare
HEPCGN_17970 +0.4 1.0 phosphopantetheine attachment site family protein compare
HEPCGN_25290 Arg_trna +0.4 1.1 tRNA-Arg(tct) compare
HEPCGN_23435 torR +0.4 1.4 two-component system response regulator TorR compare
HEPCGN_17900 hybG +0.4 1.6 hydrogenase maturation factor HybG compare
HEPCGN_24190 +0.4 1.8 hypothetical protein compare
HEPCGN_04350 mraW +0.4 0.7 DNA methyltransferase compare
HEPCGN_00115 ybcM +0.4 1.8 Uncharacterized HTH-type transcriptional regulator YbcM compare
HEPCGN_02010 ybjH +0.4 0.5 Uncharacterized protein YbjH compare
HEPCGN_03960 dcm +0.4 1.7 DNA-cytosine methyltransferase compare
HEPCGN_21070 hyfA +0.4 1.4 hydrogenase 4 subunit HyfA compare
HEPCGN_07215 ykiD +0.4 0.8 Protein YkiD compare
HEPCGN_26720 +0.4 1.9 phage tail protein compare
HEPCGN_05105 mipA +0.4 1.8 scaffolding protein MipA compare
HEPCGN_26635 gGDEF +0.4 1.9 diguanylate cyclase compare
HEPCGN_09895 +0.4 0.6 Transposase compare
HEPCGN_07345 yaiS +0.4 1.0 Uncharacterized deacetylase YaiS compare
HEPCGN_10825 hmoA +0.4 1.1 antibiotic biosynthesis monooxygenase compare
HEPCGN_10855 araC +0.4 0.5 AraC-type DNA-binding domain and AraC-containing proteins compare
HEPCGN_01135 ybfG +0.4 2.1 Putative uncharacterized protein YbfG compare
HEPCGN_26385 +0.4 1.1 leucine Rich Repeat family protein compare
HEPCGN_25075 ychT +0.4 0.9 Protein YchT compare
HEPCGN_25120 cls +0.4 0.6 cardiolipin synthase compare
HEPCGN_05100 yeaG +0.4 1.8 protein kinase YeaG compare
HEPCGN_21330 cysT +0.4 1.7 sulfate/thiosulfate ABC transporter permease CysT compare
HEPCGN_21275 amiA +0.4 2.1 N-acetylmuramoyl-L-alanine amidase AmiA compare
HEPCGN_17675 ygiB +0.4 2.3 DUF1190 domain-containing protein compare
HEPCGN_06475 purE +0.4 1.2 N5-carboxyaminoimidazole ribonucleotide mutase compare
HEPCGN_09600 fimF +0.3 1.3 type 1 fimbria minor subunit FimF compare
HEPCGN_01415 +0.3 0.9 hypothetical protein compare
HEPCGN_07030 yajL +0.3 1.3 protein deglycase YajL compare
HEPCGN_01835 dps +0.3 1.8 DNA starvation/stationary phase protection protein Dps compare
HEPCGN_02740 rcnB +0.3 1.3 Ni(II)/Co(II) efflux transporter accessory subunit RcnB compare
HEPCGN_13980 +0.3 1.8 type III cell invasion protein SipB compare
HEPCGN_24275 +0.3 0.8 hypothetical protein compare
HEPCGN_17875 hybB +0.3 2.3 Ni/Fe-hydrogenase cytochrome b subunit compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECOR38 in no phage control experiments

For no phage control No phage across organisms