Experiment set2IT090 for Pseudomonas fluorescens GW456-L13

Compare to:

LB with Aluminum chloride hydrate 5 mM

200 most important genes:

  gene name fitness t score description  
PfGW456L13_656 -4.2 -2.9 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_5011 -3.7 -3.4 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
PfGW456L13_276 -3.4 -1.6 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_4618 -3.3 -4.4 Outer membrane lipoprotein compare
PfGW456L13_644 -3.3 -7.1 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_4859 -3.2 -4.8 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_4254 -3.1 -8.5 FIG00955360: hypothetical protein compare
PfGW456L13_705 -2.7 -1.2 FIG00953800: hypothetical protein compare
PfGW456L13_2176 -2.7 -5.7 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_1735 -2.6 -4.6 Glycerol uptake facilitator protein compare
PfGW456L13_4671 -2.6 -10.5 Transcriptional regulator, Cro/CI family compare
PfGW456L13_1368 -2.5 -4.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_845 -2.5 -9.1 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_4026 -2.5 -2.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_5123 -2.5 -6.3 Ais protein, putative compare
PfGW456L13_2237 -2.5 -2.7 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4580 -2.3 -7.6 Multidrug efflux RND membrane fusion protein MexC compare
PfGW456L13_207 -2.3 -6.0 InaA protein compare
PfGW456L13_149 -2.3 -5.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_793 -2.2 -3.2 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_144 -2.2 -6.0 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_4165 -2.2 -4.5 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_622 -2.2 -8.3 Protein tyrosine/serine phosphatase conserved
PfGW456L13_69 -2.1 -1.4 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
PfGW456L13_2034 -2.1 -3.4 hypothetical protein compare
PfGW456L13_2146 -2.1 -13.4 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily conserved
PfGW456L13_773 -2.1 -5.9 Hydrogen peroxide-inducible genes activator compare
PfGW456L13_3712 -2.1 -3.4 hypothetical protein compare
PfGW456L13_4207 -2.1 -5.6 Periplasmic protease compare
PfGW456L13_1768 -2.1 -7.9 two-component system sensor protein compare
PfGW456L13_4582 -2.1 -7.1 RND efflux system, outer membrane lipoprotein CmeC compare
PfGW456L13_1766 -2.1 -7.9 PAP2 superfamily protein conserved
PfGW456L13_5089 -2.1 -1.8 Transcription termination protein NusA compare
PfGW456L13_4581 -2.0 -12.1 RND efflux system, inner membrane transporter CmeB compare
PfGW456L13_1852 -2.0 -6.7 Holliday junction DNA helicase RuvA compare
PfGW456L13_4412 -2.0 -2.8 Nitroreductase family protein compare
PfGW456L13_1363 -2.0 -4.7 Rare lipoprotein A precursor compare
PfGW456L13_4668 -2.0 -6.0 RecA protein compare
PfGW456L13_1233 -2.0 -4.8 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_2487 -2.0 -4.1 FIG00961567: hypothetical protein compare
PfGW456L13_5017 -1.9 -2.7 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_1767 -1.9 -7.3 DNA-binding response regulator ColR conserved
PfGW456L13_5028 -1.9 -13.3 FIG005080: Possible exported protein conserved
PfGW456L13_1763 -1.9 -3.7 FxsA protein compare
PfGW456L13_5074 -1.9 -1.7 1-phosphofructokinase (EC 2.7.1.56) compare
PfGW456L13_4846 -1.9 -6.6 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
PfGW456L13_50 -1.8 -5.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_4661 -1.8 -4.3 Diacylglycerol kinase (EC 2.7.1.107) compare
PfGW456L13_953 -1.8 -8.4 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_1853 -1.8 -3.3 Holliday junction DNA helicase RuvB compare
PfGW456L13_4497 -1.8 -12.5 membrane protein, putative conserved
PfGW456L13_4400 -1.8 -12.0 Aromatic amino acid transport protein AroP compare
PfGW456L13_4576 -1.8 -1.9 Transcriptional regulator, ArsR family compare
PfGW456L13_5018 -1.8 -4.0 Phosphocarrier protein, nitrogen regulation associated compare
PfGW456L13_872 -1.8 -9.7 FIG139438: lipoprotein B compare
PfGW456L13_2109 -1.7 -9.8 FIG004453: protein YceG like compare
PfGW456L13_1770 -1.7 -8.4 InaA protein compare
PfGW456L13_1236 -1.7 -9.4 Cell wall endopeptidase, family M23/M37 compare
PfGW456L13_275 -1.7 -2.3 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_1749 -1.6 -3.6 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_1204 -1.6 -10.5 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases compare
PfGW456L13_2556 -1.6 -3.1 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
PfGW456L13_1824 -1.6 -1.7 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_854 -1.6 -3.1 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_2221 -1.6 -9.4 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_5086 -1.6 -3.4 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_772 -1.6 -6.6 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
PfGW456L13_2035 -1.6 -7.4 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_2941 -1.5 -1.7 Glycerate kinase (EC 2.7.1.31) compare
PfGW456L13_201 -1.5 -3.5 Hypothetical protein FIG015671 in large core OS assembly cluster compare
PfGW456L13_3704 -1.5 -3.4 Transcriptional regulator RpiR in protein degradation cluster compare
PfGW456L13_1205 -1.5 -4.4 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_322 -1.5 -3.2 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
PfGW456L13_5152 -1.5 -3.6 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
PfGW456L13_3179 -1.4 -2.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4031 -1.4 -2.8 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
PfGW456L13_1235 -1.4 -7.1 Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-) compare
PfGW456L13_5150 -1.4 -1.8 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_1192 -1.4 -3.6 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_4451 -1.4 -4.8 ATP-dependent RNA helicase SrmB compare
PfGW456L13_1009 -1.4 -1.9 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_4433 -1.4 -1.9 FIG00955751: hypothetical protein compare
PfGW456L13_2956 -1.3 -3.2 Transcriptional regulatory protein RstA compare
PfGW456L13_2551 -1.3 -3.0 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_1889 -1.3 -2.9 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_4599 -1.3 -4.4 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
PfGW456L13_5241 -1.3 -2.2 tRNA-Thr-CGT compare
PfGW456L13_874 -1.3 -8.8 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_4645 -1.3 -9.8 AmpG permease compare
PfGW456L13_125 -1.3 -0.9 hypothetical protein compare
PfGW456L13_751 -1.3 -2.7 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
PfGW456L13_1281 -1.3 -8.4 Catalase (EC 1.11.1.6) compare
PfGW456L13_4506 -1.2 -4.6 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
PfGW456L13_2037 -1.2 -3.5 nucleoprotein/polynucleotide-associated enzyme compare
PfGW456L13_4346 -1.2 -2.7 Hpt domain protein compare
PfGW456L13_1531 -1.2 -4.7 Rieske 2Fe-2S family protein compare
PfGW456L13_1996 -1.2 -1.9 Flagellar biosynthesis protein FlgN compare
PfGW456L13_1492 -1.2 -3.5 Probable component of the lipoprotein assembly complex (forms a complex with YaeT, YfgL, and NlpB) compare
PfGW456L13_913 -1.2 -4.7 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_1982 -1.2 -2.4 Carbon storage regulator compare
PfGW456L13_3982 -1.2 -1.1 hypothetical protein compare
PfGW456L13_59 -1.2 -4.9 Sensor histidine kinase/response regulator compare
PfGW456L13_4213 -1.2 -4.9 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
PfGW456L13_2281 -1.1 -1.8 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
PfGW456L13_4134 -1.1 -1.5 hypothetical protein compare
PfGW456L13_1382 -1.1 -3.8 FOG: TPR repeat, SEL1 subfamily compare
PfGW456L13_2981 -1.1 -1.1 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_2982 -1.1 -3.1 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (from data) compare
PfGW456L13_329 -1.1 -2.5 Histidine utilization repressor compare
PfGW456L13_477 -1.1 -1.0 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_4014 -1.1 -1.2 Chromosome segregation ATPases compare
PfGW456L13_4955 -1.1 -1.1 FIG00954638: hypothetical protein compare
PfGW456L13_5077 -1.1 -4.0 Fructose repressor FruR, LacI family compare
PfGW456L13_1284 -1.1 -1.8 Putative transport protein compare
PfGW456L13_3466 -1.1 -2.1 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
PfGW456L13_2025 -1.1 -3.9 Cytochrome c-type biogenesis protein ResA compare
PfGW456L13_204 -1.1 -6.7 Carbamoyltransferase in large core OS assembly cluster compare
PfGW456L13_1829 -1.1 -1.8 glycosyl transferase, group 1 family protein compare
PfGW456L13_150 -1.0 -1.1 hypothetical protein compare
PfGW456L13_4041 -1.0 -1.7 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_1369 -1.0 -7.0 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
PfGW456L13_4028 -1.0 -3.2 FIG00954981: hypothetical protein compare
PfGW456L13_1362 -1.0 -4.1 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
PfGW456L13_4038 -1.0 -2.3 DNA topoisomerase I (EC 5.99.1.2) compare
PfGW456L13_4160 -1.0 -1.4 FIG00958237: hypothetical protein compare
PfGW456L13_3774 -1.0 -1.5 Organic hydroperoxide resistance protein compare
PfGW456L13_2314 -0.9 -1.6 ABC-type proline/glycine betaine transport systems, ATPase components compare
PfGW456L13_4819 -0.9 -4.7 ABC-type sugar transport systems, ATPase components compare
PfGW456L13_3931 -0.9 -1.0 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.n4) compare
PfGW456L13_4248 -0.9 -3.0 NLP/P60 family protein compare
PfGW456L13_1769 -0.9 -1.8 SAM-dependent methyltransferases compare
PfGW456L13_4907 -0.9 -1.8 hypothetical protein compare
PfGW456L13_1017 -0.9 -1.8 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
PfGW456L13_4424 -0.9 -3.4 FIG00953416: hypothetical protein compare
PfGW456L13_4051 -0.9 -1.3 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
PfGW456L13_842 -0.9 -3.6 Tyrosine recombinase XerC compare
PfGW456L13_4610 -0.9 -1.0 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
PfGW456L13_2321 -0.9 -1.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_2820 -0.9 -2.4 RecA/RadA recombinase compare
PfGW456L13_4820 -0.9 -1.4 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) compare
PfGW456L13_2150 -0.9 -1.4 Carbon storage regulator compare
PfGW456L13_1099 -0.9 -1.2 FIG00953563: hypothetical protein compare
PfGW456L13_4828 -0.9 -2.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_2817 -0.9 -2.4 HEAT repeat-containing protein compare
PfGW456L13_4563 -0.9 -1.7 Transcriptional activator protein LuxR compare
PfGW456L13_4836 -0.9 -4.2 Transglycosylase, Slt family compare
PfGW456L13_1538 -0.9 -5.3 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_2573 -0.9 -2.4 transcriptional regulator, MerR family compare
PfGW456L13_350 -0.8 -1.6 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_2011 -0.8 -3.3 Transcriptional regulatory protein PhoP compare
PfGW456L13_5066 -0.8 -2.7 FIG00960055: hypothetical protein compare
PfGW456L13_1153 -0.8 -4.2 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_770 -0.8 -1.3 Superfamily II DNA and RNA helicases compare
PfGW456L13_605 -0.8 -0.9 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
PfGW456L13_2883 -0.8 -4.4 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
PfGW456L13_3398 -0.8 -1.3 Transcriptional regulator, TetR family compare
PfGW456L13_2868 -0.8 -1.6 hypothetical protein compare
PfGW456L13_174 -0.8 -2.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_1027 -0.8 -1.6 Chemotaxis signal transduction protein compare
PfGW456L13_2842 -0.8 -1.7 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_2084 -0.8 -1.0 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_946 -0.8 -3.2 Outer membrane protein assembly factor YaeT precursor compare
PfGW456L13_1934 -0.8 -1.9 DGPFAETKE compare
PfGW456L13_721 -0.8 -3.9 FIG00956226: hypothetical protein compare
PfGW456L13_2581 -0.8 -1.5 Transmembrane regulator protein PrtR compare
PfGW456L13_2329 -0.8 -1.2 Endoribonuclease L-PSP compare
PfGW456L13_259 -0.8 -1.1 General secretion pathway protein K compare
PfGW456L13_3289 -0.8 -1.5 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
PfGW456L13_2602 -0.8 -4.1 putative exported protein compare
PfGW456L13_3406 -0.8 -0.9 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) compare
PfGW456L13_2224 -0.8 -4.0 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
PfGW456L13_4009 -0.8 -4.3 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_2559 -0.8 -3.8 Hydrolase, carbon-nitrogen family compare
PfGW456L13_1447 -0.8 -1.1 Transcriptional regulator, GntR family compare
PfGW456L13_1513 -0.8 -5.4 putative exported protein compare
PfGW456L13_2223 -0.8 -4.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_172 -0.7 -3.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_3565 -0.7 -1.6 heme uptake regulator compare
PfGW456L13_2651 -0.7 -2.1 Cell division protein FtsK compare
PfGW456L13_239 -0.7 -2.3 FIGfam138462: Acyl-CoA synthetase, AMP-(fatty) acid ligase / (3R)-hydroxymyristoyl-[ACP] dehydratase (EC 4.2.1.-) compare
PfGW456L13_2466 -0.7 -2.6 Porphobilinogen synthase (EC 4.2.1.24) compare
PfGW456L13_4466 -0.7 -3.0 hypothetical protein compare
PfGW456L13_1655 -0.7 -0.9 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_5003 -0.7 -1.1 YrbA protein compare
PfGW456L13_990 -0.7 -1.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_202 -0.7 -2.8 Probable transcription regulator Mig-14 compare
PfGW456L13_261 -0.7 -2.0 General secretion pathway protein I compare
PfGW456L13_3311 -0.7 -1.1 hypothetical protein compare
PfGW456L13_184 -0.7 -4.2 lipoprotein, putative compare
PfGW456L13_140 -0.7 -1.5 FIG003573: hypothetical protein compare
PfGW456L13_2402 -0.7 -2.8 FIG032225: Transcriptional regulator, LysR family compare
PfGW456L13_1523 -0.7 -1.3 Poly(A) polymerase (EC 2.7.7.19) compare
PfGW456L13_594 -0.7 -1.6 DNA polymerase I (EC 2.7.7.7) compare
PfGW456L13_1722 -0.7 -3.0 Thiol:disulfide interchange protein DsbC compare
PfGW456L13_1219 -0.7 -1.6 hypothetical protein compare
PfGW456L13_2488 -0.7 -2.8 FIG00955661: hypothetical protein compare
PfGW456L13_784 -0.7 -3.1 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_4512 -0.7 -2.7 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_1624 -0.7 -3.2 Outer membrane protein assembly factor YaeT precursor compare
PfGW456L13_1020 -0.7 -2.5 Ferric siderophore transport system, periplasmic binding protein TonB compare


Specific Phenotypes

For 9 genes in this experiment

For stress Aluminum chloride hydrate in Pseudomonas fluorescens GW456-L13

For stress Aluminum chloride hydrate across organisms