Experiment set2IT085 for Escherichia coli BW25113

Compare to:

LB with 1-ethyl-3-methylimidazolium acetate 30 mM

200 most important genes:

  gene name fitness t score description  
b3934 cytR -4.5 -6.9 DNA-binding transcriptional dual regulator (NCBI) compare
b1095 fabF -4.4 -4.3 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b0088 murD -4.4 -3.0 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b2143 cdd -3.1 -5.4 cytidine deaminase (NCBI) compare
b2567 rnc -3.1 -2.9 ribonuclease III (NCBI) compare
b0543 emrE -3.0 -11.8 multidrug efflux protein (NCBI) conserved
b3021 ygiT -2.8 -3.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b3229 sspA -2.7 -4.1 stringent starvation protein A (NCBI) compare
b4202 rpsR -2.7 -2.5 30S ribosomal protein S18 (NCBI) compare
b2620 smpB -2.6 -2.4 SsrA-binding protein (NCBI) compare
b1058 yceO -2.3 -2.2 hypothetical protein (NCBI) compare
b2318 truA -2.2 -4.3 tRNA pseudouridine synthase A (NCBI) compare
b1831 proQ -2.2 -4.6 putative solute/DNA competence effector (NCBI) compare
b3961 oxyR -2.2 -10.2 DNA-binding transcriptional dual regulator (NCBI) compare
b3725 pstB -2.2 -1.5 phosphate transporter subunit (NCBI) compare
b3121 yhaC -2.2 -3.1 hypothetical protein (NCBI) compare
b3163 nlpI -2.1 -4.8 hypothetical protein (NCBI) compare
b1830 prc -2.1 -5.2 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b1370 insH-5 -2.0 -2.2 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b3962 udhA -2.0 -8.5 putative oxidoreductase (VIMSS) compare
b0232 yafN -1.9 -1.3 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1576 ydfD -1.9 -2.7 Qin prophage; predicted protein (NCBI) compare
b0500 ybbD -1.9 -2.7 hypothetical protein (RefSeq) compare
b3390 aroK -1.9 -2.1 shikimate kinase I (NCBI) compare
b0407 yajC -1.9 -3.2 preprotein translocase subunit YajC (NCBI) compare
b3726 pstA -1.9 -5.9 phosphate transporter subunit (NCBI) compare
b0738 tolR -1.9 -2.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3636 rpmG -1.8 -2.1 50S ribosomal protein L33 (NCBI) compare
b3728 pstS -1.8 -4.1 phosphate transporter subunit (NCBI) compare
b1954 dsrA -1.8 -2.5 regulatory antisense RNA (NCBI) compare
b1499 ydeO -1.7 -2.8 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1167 ymgC -1.7 -2.4 hypothetical protein (NCBI) compare
b0739 tolA -1.7 -3.6 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3613 yibP -1.7 -4.9 putative membrane protein (VIMSS) compare
b0439 lon -1.7 -4.4 DNA-binding ATP-dependent protease La (NCBI) compare
b1841 yobA -1.6 -1.8 hypothetical protein (NCBI) compare
b4172 hfq -1.6 -2.1 RNA-binding protein Hfq (NCBI) compare
b3463 ftsE -1.6 -3.9 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4148 sugE -1.6 -4.2 suppresses groEL, may be chaperone (VIMSS) compare
b2110 yehC -1.6 -4.0 predicted periplasmic pilin chaperone (NCBI) compare
b1161 ycgX -1.6 -1.4 hypothetical protein (NCBI) compare
b2363 yfdT -1.6 -3.1 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2820 recB -1.6 -2.2 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2597 yfiA -1.5 -1.9 cold shock protein associated with 30S ribosomal subunit (NCBI) compare
b1882 cheY -1.5 -1.7 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b2847 yqeI -1.5 -6.4 predicted transcriptional regulator (NCBI) compare
b4246 pyrL -1.5 -1.8 pyrBI operon leader peptide (NCBI) compare
b4146 yjeK -1.5 -2.6 predicted lysine aminomutase (NCBI) compare
b0920 ycbC -1.5 -3.8 conserved inner membrane protein (NCBI) compare
b1677 lpp -1.5 -2.6 murein lipoprotein (NCBI) compare
b1837 yebW -1.5 -2.5 orf, hypothetical protein (VIMSS) compare
b0603 ybdO -1.5 -3.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b0740 tolB -1.4 -3.6 translocation protein TolB precursor (NCBI) compare
b1257 yciE -1.4 -3.1 hypothetical protein (NCBI) compare
b0890 ftsK -1.4 -5.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3868 glnG -1.4 -4.4 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b2352 yfdI -1.4 -3.6 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b2569 lepA -1.4 -3.6 GTP-binding protein LepA (NCBI) compare
b0726 sucA -1.4 -2.8 alpha-ketoglutarate decarboxylase (NCBI) compare
b0149 mrcB -1.4 -8.4 penicillin-binding protein 1b (NCBI) compare
b4613 dinQ -1.3 -1.7 Damage inducible, function unknown (RefSeq) compare
b4694 yagP -1.3 -3.2 no description compare
b1730 ydjO -1.3 -2.4 predicted protein (RefSeq) compare
b1497 b1497 -1.3 -2.5 putative enzyme (VIMSS) compare
b1545 pinQ -1.3 -1.4 Qin prophage; predicted site-specific recombinase (NCBI) compare
b2553 glnB -1.3 -4.0 regulatory protein P-II for glutamine synthetase (NCBI) compare
b3869 glnL -1.3 -6.0 sensory histidine kinase in two-component regulatory system with GlnG (NCBI) compare
b0400 phoR -1.3 -6.4 sensory histidine kinase in two-component regulatory system with PhoB (NCBI) compare
b2501 ppk -1.3 -6.3 polyphosphate kinase (NCBI) compare
b4451 ryhB -1.3 -1.2 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b4042 dgkA -1.3 -2.7 diacylglycerol kinase (NCBI) compare
b3290 trkA -1.3 -3.3 potassium transporter peripheral membrane component (NCBI) compare
b4497 yeeL -1.3 -4.6 no description compare
b3617 kbl -1.3 -5.6 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b0113 pdhR -1.3 -3.3 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b2830 nudH -1.3 -1.7 dinucleoside polyphosphate hydrolase (NCBI) compare
b4155 yjeA -1.3 -0.8 putative lysyl-tRNA synthetase (VIMSS) compare
b2684 mprA -1.2 -2.9 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI) compare
b4557 yidD -1.2 -2.9 hypothetical protein (NCBI) compare
b4179 vacB -1.2 -5.4 putative enzyme (VIMSS) compare
b2531 iscR -1.2 -1.1 DNA-binding transcriptional repressor (NCBI) compare
b0051 ksgA -1.2 -4.3 dimethyladenosine transferase (NCBI) compare
b3609 secB -1.2 -2.6 export protein SecB (NCBI) compare
b0737 tolQ -1.2 -2.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2699 recA -1.2 -1.7 recombinase A (NCBI) compare
b1642 slyA -1.2 -1.6 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b2510 b2510 -1.2 -3.3 orf, hypothetical protein (VIMSS) compare
b0705 ybfL -1.2 -3.0 putative receptor protein (VIMSS) compare
b1712 ihfA -1.2 -2.5 integration host factor subunit alpha (NCBI) compare
b4551 yheV -1.2 -1.8 hypothetical protein (NCBI) compare
b2055 wcaE -1.2 -2.1 predicted glycosyl transferase (NCBI) compare
b4359 mdoB -1.2 -8.4 phosphoglycerol transferase I (VIMSS) compare
b4279 yjhB -1.2 -3.2 putative transport protein (VIMSS) compare
b3131 agaR -1.2 -3.0 DNA-binding transcriptional dual regulator (NCBI) compare
b2277 nuoM -1.2 -4.3 NADH dehydrogenase subunit M (NCBI) compare
b3950 frwB -1.2 -2.4 predicted enzyme IIB component of PTS (NCBI) compare
b3781 trxA -1.1 -3.0 thioredoxin 1 (VIMSS) compare
b1409 ynbB -1.1 -4.3 predicted CDP-diglyceride synthase (NCBI) compare
b0049 apaH -1.1 -3.9 diadenosinetetraphosphatase (NCBI) compare
b2990 hybG -1.1 -2.2 hydrogenase 2 accessory protein (NCBI) compare
b0082 mraW -1.1 -2.8 S-adenosyl-methyltransferase (NCBI) compare
b1936 intG -1.1 -2.0 predicted defective phage integrase (pseudogene) (RefSeq) compare
b3228 sspB -1.1 -2.4 ClpXP protease specificity-enhancing factor (NCBI) compare
b2340 sixA -1.1 -3.1 phosphohistidine phosphatase (NCBI) compare
b3027 ygiZ -1.1 -2.3 conserved inner membrane protein (NCBI) compare
b2617 smpA -1.1 -2.4 small membrane protein A (VIMSS) compare
b3784 rfe -1.1 -7.2 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b0630 lipB -1.1 -1.7 protein of lipoate biosynthesis (VIMSS) compare
b1176 minC -1.1 -2.7 septum formation inhibitor (NCBI) compare
b4174 hflK -1.1 -5.8 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b4175 hflC -1.1 -5.5 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b0957 ompA -1.1 -2.8 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4577 sgrS -1.0 -1.4 small antisense RNA (NCBI) compare
b3741 gidA -1.0 -4.6 glucose-inhibited division protein A (NCBI) compare
b0303 ykgI -1.0 -3.2 orf, hypothetical protein (VIMSS) compare
b3616 tdh -1.0 -4.0 L-threonine 3-dehydrogenase (NCBI) compare
b2066 udk -1.0 -3.0 uridine/cytidine kinase (VIMSS) compare
b0685 ybfE -1.0 -1.6 orf, hypothetical protein (VIMSS) compare
b2784 relA -1.0 -5.3 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b1236 galU -1.0 -3.5 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1084 rne -1.0 -3.2 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b0845 ybjJ -1.0 -4.5 predicted transporter (NCBI) compare
b1684 sufA -1.0 -1.6 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b4546 ypeB -1.0 -1.2 hypothetical protein (NCBI) compare
b1125 potB -1.0 -2.5 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b4443 gcvB -1.0 -1.0 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b0866 ybjQ -1.0 -1.1 hypothetical protein (NCBI) compare
b3498 prlC -1.0 -6.7 oligopeptidase A (NCBI) compare
b4253 yjgL -1.0 -4.6 orf, hypothetical protein (VIMSS) compare
b4017 arpA -1.0 -5.2 regulator of acetyl CoA synthetase (NCBI) compare
b3644 yicC -1.0 -3.8 hypothetical protein (NCBI) compare
b1123 potD -1.0 -3.6 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b1138 ymfE -1.0 -1.2 e14 prophage; predicted inner membrane protein (NCBI) compare
b3426 glpD -1.0 -4.1 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2673 nrdH -1.0 -1.4 glutaredoxin-like protein (NCBI) compare
b2431 b2431 -1.0 -4.3 orf, hypothetical protein (VIMSS) compare
b1658 purR -1.0 -3.9 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3727 pstC -1.0 -4.1 phosphate transporter subunit (NCBI) compare
b3792 wzxE -1.0 -5.1 O-antigen translocase (NCBI) compare
b4426 isrA -1.0 -1.9 unknown RNA (NCBI) compare
b3611 yibN -1.0 -2.7 predicted rhodanese-related sulfurtransferase (NCBI) compare
b4590 ybfK -1.0 -3.1 hypothetical protein (RefSeq) compare
b0741 pal -0.9 -2.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3032 cpdA -0.9 -3.9 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b1951 rcsA -0.9 -2.7 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b2263 yfbB -0.9 -2.0 predicted peptidase (NCBI) compare
b2824 ygdB -0.9 -2.6 orf, hypothetical protein (VIMSS) compare
b1165 ymgA -0.9 -2.0 hypothetical protein (NCBI) compare
b2859 ygeO -0.9 -2.0 hypothetical protein (RefSeq) compare
b3416 malQ -0.9 -5.5 4-alpha-glucanotransferase (amylomaltase) (NCBI) compare
b2822 recC -0.9 -3.1 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2650 ypjC -0.9 -1.4 hypothetical protein (RefSeq) compare
b1085 b1085 -0.9 -0.8 orf, hypothetical protein (VIMSS) compare
b0842 cmr -0.9 -4.5 multidrug efflux system protein (NCBI) compare
b1548 nohA -0.9 -1.7 Qin prophage; predicted packaging protein (RefSeq) compare
b1863 ruvC -0.9 -2.2 Holliday junction resolvase (NCBI) compare
b1124 potC -0.9 -2.8 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b4648 ysaC -0.9 -1.7 no description compare
b1581 rspA -0.8 -1.8 predicted dehydratase (NCBI) compare
b2625 yfjI -0.8 -3.5 CP4-57 prophage; predicted protein (NCBI) compare
b3761 trpT -0.8 -1.0 tRNA-Trp (NCBI) compare
b0605 ahpC -0.8 -3.3 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b2796 sdaC -0.8 -5.6 predicted serine transporter (NCBI) compare
b1942 fliJ -0.8 -1.0 flagellar biosynthesis chaperone (NCBI) compare
b2330 yfcB -0.8 -1.5 putative adenine-specific methylase (VIMSS) compare
b1259 yciG -0.8 -1.1 orf, hypothetical protein (VIMSS) compare
b4438 cyaR -0.8 -1.3 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b0527 ybcI -0.8 -2.5 conserved inner membrane protein (NCBI) compare
b3462 ftsX -0.8 -3.3 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b1363 trkG -0.8 -2.5 Rac prophage; potassium transporter subunit (NCBI) compare
b4163 glyV -0.8 -1.1 tRNA-Gly (NCBI) compare
b3504 yhiS -0.8 -2.1 hypothetical protein (RefSeq) compare
b4640 yoeG -0.8 -4.2 no description compare
b1130 phoP -0.8 -3.5 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3250 mreC -0.8 -1.3 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b1150 ymfR -0.8 -0.8 e14 prophage; predicted protein (NCBI) compare
b2392 mntH -0.8 -3.6 manganese transport protein MntH (NCBI) compare
b1040 csgD -0.8 -2.5 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b3082 ygjM -0.8 -1.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b0729 sucD -0.8 -1.7 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3816 corA -0.8 -3.9 magnesium/nickel/cobalt transporter (NCBI) compare
b2132 bglX -0.8 -4.4 beta-D-glucoside glucohydrolase, periplasmic (NCBI) compare
b3803 hemX -0.8 -4.8 predicted uroporphyrinogen III methylase (NCBI) compare
b1505 ydeT -0.8 -3.0 hypothetical protein (RefSeq) compare
b4128 yjdK -0.8 -1.6 hypothetical protein (NCBI) compare
b2006 yeeW -0.8 -1.9 CP4-44 prophage; predicted protein (RefSeq) compare
b1249 cls -0.8 -3.4 cardiolipin synthetase (NCBI) compare
b0367 tauC -0.8 -2.1 taurine transporter subunit (NCBI) compare
b0226 dinJ -0.8 -1.3 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b3120 yhaB -0.8 -2.0 orf, hypothetical protein (VIMSS) compare
b1279 yciS -0.8 -1.0 conserved inner membrane protein (NCBI) compare
b2343 b2343 -0.8 -1.1 orf, hypothetical protein (VIMSS) compare
b1126 potA -0.8 -2.7 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b1615 uidC -0.8 -3.1 membrane-associated protein (VIMSS) compare
b1192 ldcA -0.8 -2.4 L,D-carboxypeptidase A (NCBI) compare
b4685 yrbN -0.8 -1.5 expressed protein (RefSeq) compare
b2910 zapA -0.7 -2.3 protein that localizes to the cytokinetic ring (NCBI) compare
b4647 mokA -0.7 -1.0 no description compare
b3811 xerC -0.7 -1.5 site-specific tyrosine recombinase XerC (NCBI) compare
b1429 tehA -0.7 -1.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare


Specific Phenotypes

For 9 genes in this experiment

For stress 1-ethyl-3-methylimidazolium acetate in Escherichia coli BW25113

For stress 1-ethyl-3-methylimidazolium acetate across organisms