Experiment set2IT077 for Escherichia coli BL21

Compare to:

P2_phage_0.5625_MOI

200 most important genes:

  gene name fitness t score description  
ECD_03846 -6.8 -4.7 oxidative and nitrosative stress transcriptional regulator compare
ECD_04170 -5.6 -2.4 putative enzyme IIB component of PTS compare
ECD_04018 -5.4 -1.1 entericidin A membrane lipoprotein, antidote entericidin B compare
ECD_03687 -5.4 -1.8 site-specific tyrosine recombinase compare
ECD_03731 -5.4 -4.3 TatABCE protein translocation system subunit compare
ECD_03583 -5.2 -14.8 gap repair protein compare
ECD_00006 -5.2 -3.6 peroxide resistance protein, lowers intracellular iron compare
ECD_02331 -5.0 -2.2 porphyrinogen oxidase, cytoplasmic compare
ECD_02889 -4.9 -3.4 septal ring component that protects the divisome from stress; multicopy suppressor of ftsI(Ts) compare
ECD_00596 -4.9 -0.9 TatABCE protein translocation system subunit compare
ECD_02377 -4.8 -1.6 hydrogenase 4, membrane subunit compare
ECD_01864 -4.8 -1.6 universal stress protein compare
ECD_03257 -4.8 -2.4 response regulator in two-component regulatory system with EnvZ compare
ECD_02443 -4.7 -2.6 serine hydroxymethyltransferase compare
ECD_03509 -4.7 -7.8 ATP-dependent DNA helicase compare
ECD_03685 -4.6 -3.1 diaminopimelate epimerase compare
ECD_02459 -4.6 -1.8 gap repair protein compare
ECD_00774 -4.5 -1.5 23S rRNA m(6)A1618 methyltransferase, SAM-dependent compare
ECD_04193 -4.4 -1.5 fructuronate-inducible hexuronate regulon transcriptional repressor; autorepressor compare
ECD_02907 -4.4 -3.1 transport channel compare
ECD_02140 -4.4 -1.9 fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase compare
ECD_04038 -4.4 -1.7 delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase compare
ECD_00960 -4.4 -1.5 Ter macrodomain organizer matS-binding protein compare
ECD_02724 -4.4 -11.2 ssDNA exonuclease, 5 compare
ECD_01842 -4.3 -1.4 tRNA (cmo5U34)-carboxymethyltransferase, carboxy-SAM-dependent compare
ECD_00423 -4.3 -3.3 gap repair protein compare
ECD_03121 -4.2 -0.8 putative membrane protein compare
ECD_03242 -4.2 -1.6 shikimate kinase I compare
ECD_04119 -4.2 -0.8 SopA-central-domain-like hexapeptide repeat protein compare
ECD_04042 -4.2 -2.8 HflB protease modulator specific for phage lambda cII repressor compare
ECD_03256 -4.2 -7.5 sensory histidine kinase in two-component regulatory system with OmpR compare
ECD_00687 -4.1 -3.0 succinyl-CoA synthetase, beta subunit compare
ECD_01795 -4.1 -1.8 putative inner membrane protein compare
ECD_02162 -4.1 -0.8 ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance compare
ECD_02857 -4.1 -0.8 hypothetical protein compare
ECD_03486 -4.1 -4.9 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_02694 -4.0 -0.8 putative LuxR family transcriptional regulator compare
ECD_01048 -4.0 -1.4 multicopy suppressor of secY and secA compare
ECD_01042 -4.0 -1.3 O-acetyl-ADP-ribose deacetylase; RNase III inhibitor during cold shock; putative cardiolipin synthase C regulatory subunit compare
ECD_03144 -4.0 -0.8 DUF1992 family protein compare
ECD_00569 -3.9 -1.7 Spo0J family protein, ParB-like nuclease domain compare
ECD_02038 -3.9 -0.8 hypothetical protein compare
ECD_03119 -3.9 -1.5 global DNA-binding transcriptional dual regulator compare
ECD_02738 -3.9 -1.8 2-octaprenylphenol hydroxylase, FAD-dependent compare
ECD_02400 -3.9 -3.5 IMP dehydrogenase compare
ECD_00807 -3.8 -0.7 deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx compare
ECD_03625 -3.8 -5.7 5-methylaminomethyl-2-thiouridine modification at tRNA U34 compare
ECD_01591 -3.7 -1.3 PLP-dependent beta-cystathionase and maltose regulon regulator compare
ECD_00434 -3.7 -0.7 putative DNA-binding transcriptional regulator compare
ECD_02250 -3.7 -0.7 uncharacterized protein compare
ECD_00366 -3.7 -2.3 phosphatidylglycerophosphatase A compare
ECD_02036 -3.7 -0.7 hypothetical protein compare
ECD_01792 -3.7 -1.4 23S rRNA m(1)G745 methyltransferase, SAM-dependent compare
ECD_02507 -3.7 -1.6 toxic UPF0083 family protein inhibitor of 70S ribosome formation compare
ECD_00015 -3.7 -4.3 chaperone Hsp40, DnaK co-chaperone compare
ECD_01409 -3.7 -1.2 ATP-binding protein, periplasmic, function unknown compare
ECD_02622 -3.6 -2.5 7-carboxy-7-deazaguanine synthase; queosine biosynthesis compare
ECD_03005 -3.6 -1.7 N-acetylgalactosamine-specific enzyme IIB component of PTS compare
ECD_03451 -3.6 -1.3 TPR-like repeat protein compare
ECD_02726 -3.6 -2.5 site-specific tyrosine recombinase compare
ECD_03238 -3.6 -3.6 D-ribulose-5-phosphate 3-epimerase compare
ECD_00673 -3.5 -1.9 UPF0271 family protein compare
ECD_00594 -3.5 -1.8 fluoride efflux channel, dual topology membrane protein compare
ECD_01584 -3.5 -1.5 putative outer membrane porin for beta-glucuronides porin protein compare
ECD_00574 -3.5 -3.3 alkyl hydroperoxide reductase, C22 subunit compare
ECD_01645 -3.4 -1.1 pyruvate kinase I compare
ECD_01800 -3.4 -1.5 putative endopeptidase compare
ECD_00367 -3.4 -3.2 2-carboxybenzaldehyde reductase compare
ECD_02039 -3.3 -0.6 hypothetical protein compare
ECD_03818 -3.3 -2.4 essential cell division protein compare
ECD_01022 -3.3 -1.3 ATP-binding protein; putative PhoH family P-loop ATPase compare
ECD_01445 -3.3 -1.1 D,D-dipeptide ABC transporter periplasmic binding protein compare
ECD_01074 -3.3 -2.5 flagellar component of cell-distal portion of basal-body rod compare
ECD_00439 -3.3 -1.6 inner membrane protein; stimulator of the QmcA suppressor of ftsH-htpX compare
ECD_00760 -3.3 -3.2 putative ABC transporter permease compare
ECD_01220 -3.3 -2.3 oligopeptide ABC transporter ATPase compare
ECD_01195 -3.3 -0.6 cation transport regulator compare
ECD_01349 -3.2 -1.2 pyruvate-flavodoxin oxidoreductase compare
ECD_01775 -3.2 -1.1 acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase) compare
ECD_03067 -3.2 -1.5 RNA polymerase, sigma 54 (sigma N) factor compare
ECD_01043 -3.2 -2.7 stationary phase cardiolipin synthase 3 compare
ECD_00559 -3.1 -2.4 ferrienterobactin ABC transporter periplasmic binding protein compare
ECD_03021 -3.1 -1.2 UPF0306 family protein compare
ECD_00495 -3.1 -2.1 inactive polymorphonuclear leukocyte migration suppressor; DLP12 prophage; UPF0098 family secreted protein compare
ECD_00746 -3.1 -5.7 exision nuclease of nucleotide excision repair, DNA damage recognition component compare
ECD_01946 -3.1 -0.8 dTDP-L-rhamnose synthase, NAD(P)-dependent dTDP-4-dehydrorhamnose reductase subunit compare
ECD_01105 -3.1 -3.2 respiratory NADH dehydrogenase 2/cupric reductase compare
ECD_01744 -3.1 -0.9 putative MFS sugar transporter, membrane protein compare
ECD_03590 -3.1 -2.7 tRNA U34 5-methylaminomethyl-2-thiouridine modification GTPase compare
ECD_01606 -3.1 -1.0 pyridoxamine kinase compare
ECD_02399 -3.1 -1.9 GMP synthetase (glutamine aminotransferase) compare
ECD_00681 -3.1 -0.8 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_01914 -3.1 -2.4 exodeoxyribonuclease I; exonuclease I compare
ECD_01679 -3.1 -0.8 glutathione peroxidase compare
ECD_00192 -3.0 -2.6 putative lipoprotein compare
ECD_01561 -3.0 -1.0 H(+)/Cl(-) exchange transporter compare
ECD_03349 -3.0 -8.1 glutathione oxidoreductase compare
ECD_03729 -2.9 -1.3 TatABCE protein translocation system subunit compare
ECD_02508 -2.9 -1.5 tmRNA-binding trans-translation protein compare
ECD_00867 -2.9 -1.4 arginine ABC transporter permease compare
ECD_01162 -2.9 -1.0 fatty acid metabolism regulon transcriptional regulator compare
ECD_02792 -2.9 -1.1 oxidative damage protective factor for iron-sulfur proteins compare
ECD_00949 -2.9 -1.4 dihydro-orotate oxidase, FMN-linked compare
ECD_02432 -2.9 -0.8 3-phenylpropionate dioxygenase, ferredoxin subunit compare
ECD_01109 -2.9 -1.1 L,D-transpeptidase linking Lpp to murein compare
ECD_01479 -2.9 -1.0 putative membrane-bound diguanylate cyclase compare
ECD_01014 -2.9 -1.6 ureidoacrylate amidohydrolase compare
ECD_02238 -2.9 -1.1 colicin V production protein compare
ECD_00575 -2.8 -3.8 alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding compare
ECD_03075 -2.8 -7.6 aerobic respiration control sensor histidine protein kinase, cognate to two-component response regulators ArcA and RssB compare
ECD_03727 -2.8 -2.1 aerobic ubiquinone synthesis protein, SCP2 family protein compare
ECD_02946 -2.8 -1.5 evolved beta-D-galactosidase, beta subunit; cupin superfamily compare
ECD_00813 -2.8 -0.8 transcriptional regulator of csgD and ybiJI; autoregulator compare
ECD_03817 -2.8 -2.9 peptidase component of the HslUV protease compare
ECD_02584 -2.8 -1.4 serine/threonine-specific protein phosphatase 2 compare
ECD_01887 -2.8 -1.3 inner membrane heme subunit for periplasmic YedYZ reductase compare
ECD_03591 -2.8 -1.3 tryptophanase leader peptide compare
ECD_01273 -2.8 -0.9 putrescine importer compare
ECD_01650 -2.8 -1.4 component of SufBCD Fe-S cluster assembly scaffold compare
ECD_01972 -2.7 -2.1 uridine/cytidine kinase compare
ECD_02765 -2.7 -4.5 transketolase 1, thiamine triphosphate-binding compare
ECD_01950 -2.7 -0.7 putative glycosyl transferase compare
ECD_02093 -2.7 -1.6 putative nucleoside transporter compare
ECD_01818 -2.7 -0.5 extracellular Colicin M immunity family protein compare
ECD_00889 -2.7 -0.9 leucyl/phenylalanyl-tRNA-protein transferase compare
ECD_02042 -2.7 -0.7 DUF2574 family protein compare
ECD_01664 -2.7 -0.5 putative acyl-CoA dehydrogenase compare
ECD_01452 -2.6 -1.0 putative periplasmic M16 family zinc metalloendopeptidase compare
ECD_04107 -2.6 -3.3 trehalose-6-P hydrolase compare
ECD_02667 -2.6 -8.6 exonuclease V (RecBCD complex), alpha chain compare
ECD_02254 -2.6 -1.7 chorismate synthase compare
ECD_01910 -2.6 -0.7 UPF0265 family protein compare
ECD_00501 -2.6 -1.5 uncharacterized protein, DLP12 prophage compare
ECD_01773 -2.6 -0.9 putative YeaWX dioxygenase beta subunit, reductase component compare
ECD_01216 -2.6 -1.4 UPF0056 family inner membrane protein compare
ECD_01952 -2.6 -3.1 putative colanic acid exporter compare
ECD_01575 -2.6 -0.7 dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme compare
ECD_00838 -2.6 -1.6 putative phage tail protein compare
ECD_01774 -2.6 -0.7 ribonuclease D compare
ECD_00933 -2.6 -2.5 outer membrane porin 1a (Ia compare
ECD_01700 -2.5 -0.7 cell division modulator compare
ECD_02286 -2.5 -0.7 putative lipoprotein involved in colanic acid biosynthesis compare
ECD_00904 -2.5 -0.7 LysR family putative transcriptional regulator compare
ECD_01482 -2.5 -0.9 succinate semialdehyde dehydrogenase, NAD(P)+-dependent compare
ECD_01219 -2.5 -1.3 oligopeptide ABC transporter permease compare
ECD_01785 -2.5 -1.7 putative membrane-anchored cyclic-di-GMP phosphodiesterase, regulator of cellulose production compare
ECD_02652 -2.5 -2.9 hypothetical protein compare
ECD_02549 -2.5 -8.1 DNA recombination and repair protein; ssDNA-dependent ATPase; synaptase; ssDNA and dsDNA binding protein; ATP-dependent homologous DNA strand exchanger; recombinase A; LexA autocleavage cofactor compare
ECD_01472 -2.5 -0.8 autoinducer 2 import system permease protein compare
ECD_00802 -2.5 -1.4 ribosomal protein S12 methylthiotransferase compare
ECD_01838 -2.5 -2.4 isochorismatase family protein compare
ECD_03355 -2.5 -0.7 Putative LuxR family repressor for dicarboxylate transport compare
ECD_01312 -2.5 -0.8 O-6-alkylguanine-DNA:cysteine-protein methyltransferase compare
ECD_04049 -2.4 -0.9 PspA/IM30 family protein compare
ECD_01399 -2.4 -0.9 putative ABC transporter permease compare
ECD_02110 -2.4 -3.3 microcin C ABC transporter ATPase compare
ECD_04389 -2.4 -1.7 hypothetical protein compare
ECD_01168 -2.4 -0.7 lytic murein endotransglycosylase E compare
ECD_03571 -2.4 -0.6 DUF1375 family outer membrane protein compare
ECD_03086 -2.4 -3.3 sialic acid-inducible nan operon repressor compare
ECD_01582 -2.4 -0.8 mannose-6-phosphate isomerase compare
ECD_02548 -2.4 -2.4 regulatory protein for RecA compare
ECD_00695 -2.4 -0.9 putative inner membrane protein in cydABX-ybgE operon compare
ECD_01039 -2.4 -0.6 curlin subunit, amyloid curli fibers, cryptic compare
ECD_00864 -2.4 -2.4 23S rRNA m(5)U747 methyltransferase, SAM-dependent compare
ECD_00402 -2.4 -1.0 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB compare
ECD_00983 -2.3 -2.3 phosphoanhydride phosphorylase compare
ECD_03653 -2.3 -2.2 peptidyl-prolyl cis-trans isomerase C (rotamase C) compare
ECD_01586 -2.3 -0.8 beta-D-glucuronidase compare
ECD_00342 -2.3 -3.4 nucleoid-associated ssDNA and dsDNA binding protein; competitive inhibitor of RecA function compare
ECD_03733 -2.3 -5.8 transcription antitermination protein compare
ECD_01763 -2.3 -0.6 diguanylate cyclase compare
ECD_03998 -2.3 -1.4 GNAT family putative N-acetyltransferase compare
ECD_01630 -2.3 -0.9 LysR family putative transcriptional regulator compare
ECD_01011 -2.3 -0.6 putative malonic semialdehyde reductase compare
ECD_04194 -2.3 -1.5 uncharacterized protein compare
ECD_00880 -2.3 -1.2 aquaporin Z compare
ECD_02909 -2.2 -2.5 DUF1190 family protein compare
ECD_00405 -2.2 -2.0 outer membrane lipoprotein compare
ECD_00811 -2.2 -1.5 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase; pyrimidine phosphatase; riboflavin synthesis compare
ECD_00260 -2.2 -1.4 reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide-dependent disulfide oxidoreductase family compare
ECD_00896 -2.2 -2.6 recombination intermediate processing DNA-dependent ATPase compare
ECD_01655 -2.2 -1.0 1,4-dihydroxy-2-naphthoyl-CoA hydrolase compare
ECD_02052 -2.2 -2.0 lipoprotein, DUF1307 family compare
ECD_01365 -2.2 -0.9 putative esterase compare
ECD_01667 -2.2 -1.0 putative electron transfer flavoprotein, FAD-binding subunit compare
ECD_01498 -2.2 -0.6 NADP-dependent 3-hydroxy acid dehydrogenase; malonic semialdehyde reductase compare
ECD_03735 -2.1 -5.4 NAD(P)H-flavin reductase compare
ECD_02310 -2.1 -1.0 DUF3820 family protein compare
ECD_03207 -2.1 -1.3 OsmC family protein compare
ECD_01314 -2.1 -2.2 p-aminobenzoyl-glutamate hydrolase, B subunit compare
ECD_00999 -2.1 -2.1 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit compare
ECD_01529 -2.1 -0.6 Qin prophage; uncharacterized protein compare
ECD_01063 -2.1 -1.3 UPF0502 family protein compare
ECD_04309 -2.1 -0.8 uncharacterized protein compare
ECD_04147 -2.1 -1.7 hypothetical protein compare
ECD_01166 -2.1 -1.3 putative cation/proton antiporter compare
ECD_01130 -2.1 -2.0 putative lysogenization regulator compare
ECD_01565 -2.1 -0.6 putative arabinose efflux transporter compare
ECD_02404 -2.1 -1.2 BamABCDE complex OM biogenesis lipoprotein compare


Specific Phenotypes

For 2 genes in this experiment

For phage P2_phage in Escherichia coli BL21

For phage P2_phage across organisms