Experiment set2IT076 for Escherichia coli BW25113

Compare to:

LB with syringaldehyde 5 mM

200 most important genes:

  gene name fitness t score description  
b3792 wzxE -3.7 -4.4 O-antigen translocase (NCBI) compare
b2330 yfcB -3.0 -2.8 putative adenine-specific methylase (VIMSS) compare
b0683 fur -2.7 -2.5 ferric uptake regulator (NCBI) compare
b0630 lipB -2.5 -2.4 protein of lipoate biosynthesis (VIMSS) compare
b2287 nuoB -2.3 -4.4 NADH dehydrogenase subunit B (NCBI) compare
b4172 hfq -2.2 -2.1 RNA-binding protein Hfq (NCBI) compare
b2894 xerD -2.2 -1.5 site-specific tyrosine recombinase XerD (NCBI) compare
b4042 dgkA -2.2 -3.5 diacylglycerol kinase (NCBI) compare
b3052 rfaE -2.2 -5.3 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0222 lpcA -2.1 -3.1 phosphoheptose isomerase (NCBI) compare
b2297 pta -2.1 -1.9 phosphate acetyltransferase (NCBI) compare
b2055 wcaE -2.1 -4.3 predicted glycosyl transferase (NCBI) compare
b1236 galU -2.0 -5.6 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2286 nuoC -2.0 -6.0 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0912 ihfB -1.9 -3.7 integration host factor subunit beta (NCBI) compare
b0439 lon -1.9 -5.1 DNA-binding ATP-dependent protease La (NCBI) compare
b0726 sucA -1.9 -3.1 alpha-ketoglutarate decarboxylase (NCBI) compare
b3842 rfaH -1.9 -4.4 transcriptional activator RfaH (NCBI) compare
b3619 rfaD -1.9 -2.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1712 ihfA -1.9 -3.4 integration host factor subunit alpha (NCBI) compare
b3631 rfaG -1.9 -12.5 glucosyltransferase I (NCBI) compare
b4505 insX -1.9 -1.7 predicted IS protein (RefSeq) compare
b1863 ruvC -1.8 -3.8 Holliday junction resolvase (NCBI) compare
b3839 tatC -1.8 -8.0 TatABCE protein translocation system subunit (NCBI) compare
b3630 rfaP -1.8 -9.4 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b0738 tolR -1.8 -3.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2567 rnc -1.7 -2.2 ribonuclease III (NCBI) compare
b2276 nuoN -1.7 -5.2 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b2820 recB -1.7 -2.2 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2512 yfgL -1.7 -4.1 protein assembly complex, lipoprotein component (NCBI) compare
b0957 ompA -1.7 -3.1 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3649 rpoZ -1.7 -2.9 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3621 rfaC -1.7 -4.4 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0053 surA -1.7 -3.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2518 ndk -1.7 -2.6 nucleoside diphosphate kinase (NCBI) compare
b0200 gmhB -1.7 -1.8 hypothetical protein (NCBI) compare
b3390 aroK -1.6 -2.1 shikimate kinase I (NCBI) compare
b3725 pstB -1.6 -2.1 phosphate transporter subunit (NCBI) compare
b2279 nuoK -1.6 -2.0 NADH dehydrogenase subunit K (NCBI) compare
b3636 rpmG -1.6 -2.0 50S ribosomal protein L33 (NCBI) compare
b0737 tolQ -1.5 -3.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0741 pal -1.5 -3.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3863 polA -1.5 -1.0 DNA polymerase I (NCBI) compare
b0890 ftsK -1.5 -6.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0739 tolA -1.5 -3.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2281 nuoI -1.5 -2.2 NADH dehydrogenase subunit I (NCBI) compare
b3728 pstS -1.5 -3.7 phosphate transporter subunit (NCBI) compare
b2277 nuoM -1.4 -5.3 NADH dehydrogenase subunit M (NCBI) compare
b3035 tolC -1.4 -6.7 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3483 yhhH -1.4 -2.0 orf, hypothetical protein (VIMSS) compare
b1130 phoP -1.4 -5.9 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2278 nuoL -1.4 -7.0 NADH dehydrogenase subunit L (NCBI) compare
b1167 ymgC -1.4 -2.2 hypothetical protein (NCBI) compare
b3609 secB -1.4 -3.8 export protein SecB (NCBI) compare
b0705 ybfL -1.4 -3.4 putative receptor protein (VIMSS) compare
b1677 lpp -1.4 -2.7 murein lipoprotein (NCBI) compare
b2280 nuoJ -1.4 -4.3 NADH dehydrogenase subunit J (NCBI) compare
b0728 sucC -1.4 -4.4 succinyl-CoA synthetase subunit beta (NCBI) compare
b3290 trkA -1.3 -2.9 potassium transporter peripheral membrane component (NCBI) compare
b0953 rmf -1.3 -2.4 ribosome modulation factor (NCBI) compare
b0729 sucD -1.3 -2.8 succinyl-CoA synthetase subunit alpha (NCBI) compare
b0049 apaH -1.3 -4.4 diadenosinetetraphosphatase (NCBI) compare
b4551 yheV -1.3 -2.5 hypothetical protein (NCBI) compare
b2283 nuoG -1.3 -5.3 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3632 rfaQ -1.3 -10.8 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3463 ftsE -1.3 -3.8 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1257 yciE -1.3 -2.4 hypothetical protein (NCBI) compare
b2906 visC -1.3 -4.6 hypothetical protein (NCBI) compare
b1545 pinQ -1.3 -1.6 Qin prophage; predicted site-specific recombinase (NCBI) compare
b3121 yhaC -1.3 -2.1 hypothetical protein (NCBI) compare
b3162 deaD -1.3 -3.7 inducible ATP-independent RNA helicase (VIMSS) compare
b4647 mokA -1.3 -1.6 no description compare
b2754 ygbF -1.3 -2.0 orf, hypothetical protein (VIMSS) compare
b3261 fis -1.3 -2.9 DNA-binding protein Fis (NCBI) compare
b3026 qseC -1.3 -3.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4202 rpsR -1.2 -1.8 30S ribosomal protein S18 (NCBI) compare
b4239 treC -1.2 -3.6 trehalose-6-P hydrolase (NCBI) compare
b3163 nlpI -1.2 -3.7 hypothetical protein (NCBI) compare
b2288 nuoA -1.2 -2.5 NADH dehydrogenase I chain A (VIMSS) compare
b2699 recA -1.2 -1.8 recombinase A (NCBI) compare
b3620 rfaF -1.2 -3.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3500 gor -1.2 -1.1 glutathione reductase (NCBI) compare
b4146 yjeK -1.2 -2.4 predicted lysine aminomutase (NCBI) compare
b3229 sspA -1.2 -3.0 stringent starvation protein A (NCBI) compare
b4585 sroB -1.2 -1.1 Novel sRNA, function unknown (RefSeq) compare
b0740 tolB -1.2 -3.4 translocation protein TolB precursor (NCBI) compare
b3806 cyaA -1.2 -4.1 adenylate cyclase (NCBI) compare
b1613 manA -1.1 -2.1 mannose-6-phosphate isomerase (VIMSS) compare
b0118 acnB -1.1 -2.5 aconitate hydratase (NCBI) compare
b0723 sdhA -1.1 -6.3 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b4685 yrbN -1.1 -2.3 expressed protein (RefSeq) compare
b4546 ypeB -1.1 -1.4 hypothetical protein (NCBI) compare
b3002 yqhA -1.1 -1.7 hypothetical protein (NCBI) compare
b3781 trxA -1.1 -3.0 thioredoxin 1 (VIMSS) compare
b2830 nudH -1.1 -1.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b1855 lpxM -1.1 -3.8 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2822 recC -1.1 -3.5 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0722 sdhD -1.1 -3.1 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b2343 b2343 -1.1 -1.3 orf, hypothetical protein (VIMSS) compare
b2284 nuoF -1.1 -3.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0721 sdhC -1.1 -2.6 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b3006 exbB -1.1 -4.8 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b0406 tgt -1.1 -4.8 queuine tRNA-ribosyltransferase (NCBI) compare
b1192 ldcA -1.1 -3.4 L,D-carboxypeptidase A (NCBI) compare
b3791 rffA -1.1 -5.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0720 gltA -1.0 -3.8 citrate synthase (NCBI) compare
b2346 vacJ -1.0 -4.8 predicted lipoprotein (NCBI) compare
b2625 yfjI -1.0 -4.1 CP4-57 prophage; predicted protein (NCBI) compare
b1576 ydfD -1.0 -2.3 Qin prophage; predicted protein (NCBI) compare
b3192 yrbC -1.0 -5.4 predicted ABC-type organic solvent transporter (NCBI) compare
b0500 ybbD -1.0 -1.9 hypothetical protein (RefSeq) compare
b3205 yhbJ -1.0 -2.8 hypothetical protein (NCBI) compare
b2457 cchA -1.0 -2.7 detox protein (VIMSS) compare
b3199 yrbK -1.0 -1.8 hypothetical protein (NCBI) compare
b1850 eda -1.0 -1.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b1150 ymfR -1.0 -1.1 e14 prophage; predicted protein (NCBI) compare
b1164 ycgZ -1.0 -1.8 hypothetical protein (NCBI) compare
b3194 yrbE -1.0 -5.9 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2282 nuoH -1.0 -2.2 NADH dehydrogenase subunit H (NCBI) compare
b2110 yehC -1.0 -3.1 predicted periplasmic pilin chaperone (NCBI) compare
b3935 priA -1.0 -2.0 primosome assembly protein PriA (NCBI) compare
b0114 aceE -1.0 -1.5 pyruvate dehydrogenase subunit E1 (NCBI) compare
b1438 ydcQ -1.0 -2.2 predicted DNA-binding transcriptional regulator (RefSeq) compare
b3164 pnp -1.0 -1.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0386 proC -1.0 -3.9 pyrroline-5-carboxylate reductase (NCBI) compare
b2642 yfjW -1.0 -2.1 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2531 iscR -1.0 -1.0 DNA-binding transcriptional repressor (NCBI) compare
b1290 sapF -1.0 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0051 ksgA -1.0 -3.7 dimethyladenosine transferase (NCBI) compare
b2847 yqeI -0.9 -4.6 predicted transcriptional regulator (NCBI) compare
b3195 yrbF -0.9 -5.5 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1370 insH-5 -0.9 -1.5 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b4345 mcrC -0.9 -2.5 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI) compare
b0471 ybaB -0.9 -2.4 hypothetical protein (NCBI) compare
b3838 tatB -0.9 -4.4 sec-independent translocase (NCBI) compare
b3764 yifE -0.9 -3.0 hypothetical protein (NCBI) compare
b4375 prfC -0.9 -4.1 peptide chain release factor 3 (NCBI) compare
b3741 gidA -0.9 -4.2 glucose-inhibited division protein A (NCBI) compare
b1861 ruvA -0.9 -1.4 Holliday junction DNA helicase motor protein (NCBI) compare
b2650 ypjC -0.9 -1.1 hypothetical protein (RefSeq) compare
b3191 yrbB -0.9 -4.5 orf, hypothetical protein (VIMSS) compare
b1317 ycjU -0.9 -2.7 predicted beta-phosphoglucomutase (NCBI) compare
b1499 ydeO -0.9 -1.7 predicted DNA-binding transcriptional acfivator (NCBI) compare
b4497 yeeL -0.9 -3.6 no description compare
b1434 ydcN -0.9 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2673 nrdH -0.9 -1.9 glutaredoxin-like protein (NCBI) compare
b2058 wcaB -0.9 -0.9 predicted acyl transferase (NCBI) compare
b1918 yecS -0.9 -2.3 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2285 nuoE -0.9 -1.4 NADH dehydrogenase subunit E (NCBI) compare
b1409 ynbB -0.9 -3.4 predicted CDP-diglyceride synthase (NCBI) compare
b2352 yfdI -0.9 -3.0 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b3870 glnA -0.9 -1.7 glutamine synthetase (NCBI) compare
b1942 fliJ -0.9 -1.1 flagellar biosynthesis chaperone (NCBI) compare
b1685 ydiH -0.9 -1.1 predicted protein (RefSeq) compare
b0724 sdhB -0.9 -3.1 succinate dehydrogenase, FeS subunit (NCBI) compare
b4651 yibW -0.9 -1.3 no description compare
b4481 rffT -0.9 -3.7 4-alpha-L-fucosyltransferase (NCBI) compare
b3062 ttdB -0.9 -2.8 L(+)-tartrate dehydratase (NCBI) compare
b3120 yhaB -0.8 -2.6 orf, hypothetical protein (VIMSS) compare
b3766 ilvL -0.8 -1.9 ilvG operon leader peptide (NCBI) compare
b4253 yjgL -0.8 -3.9 orf, hypothetical protein (VIMSS) compare
b3627 rfaI -0.8 -6.2 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b0013 yaaI -0.8 -2.8 hypothetical protein (NCBI) compare
b0463 acrA -0.8 -4.7 multidrug efflux system (NCBI) compare
b3617 kbl -0.8 -4.0 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b0232 yafN -0.8 -0.9 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1351 racC -0.8 -2.2 Rac prophage; predicted protein (NCBI) compare
b1465 narV -0.8 -1.4 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b4163 glyV -0.8 -1.1 tRNA-Gly (NCBI) compare
b4426 isrA -0.8 -1.8 unknown RNA (NCBI) compare
b1291 sapD -0.8 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0605 ahpC -0.8 -2.8 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b3836 b3836 -0.8 -2.3 orf, hypothetical protein (VIMSS) compare
b3790 rffC -0.8 -3.0 TDP-fucosamine acetyltransferase (RefSeq) compare
b3442 yhhZ -0.8 -1.5 hypothetical protein (NCBI) compare
b2998 yghW -0.8 -2.9 hypothetical protein (NCBI) compare
b3628 rfaB -0.8 -5.8 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b0428 cyoE -0.8 -3.1 protoheme IX farnesyltransferase (NCBI) compare
b1989 asnV -0.8 -1.6 tRNA-Asn (NCBI) compare
b1161 ycgX -0.8 -0.9 hypothetical protein (NCBI) compare
b1551 b1551 -0.8 -1.4 orf, hypothetical protein (VIMSS) compare
b0303 ykgI -0.8 -2.4 orf, hypothetical protein (VIMSS) compare
b3871 bipA -0.8 -4.7 GTP-binding protein (NCBI) compare
b4695 ykgT -0.8 -1.0 no description compare
b3398 yrfF -0.8 -1.9 predicted inner membrane protein (NCBI) compare
b0432 cyoA -0.8 -4.5 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b1363 trkG -0.8 -2.8 Rac prophage; potassium transporter subunit (NCBI) compare
b2659 b2659 -0.8 -1.3 orf, hypothetical protein (VIMSS) compare
b3462 ftsX -0.8 -3.1 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0407 yajC -0.7 -1.8 preprotein translocase subunit YajC (NCBI) compare
b2479 gcvR -0.7 -2.2 transcriptional regulation of gcv operon (VIMSS) compare
b4444 rygA -0.7 -1.8 unknown RNA (NCBI) compare
b0836 yliH -0.7 -1.6 hypothetical protein (NCBI) compare
b0782 moaB -0.7 -1.4 molybdopterin biosynthesis protein B (NCBI) compare
b3706 trmE -0.7 -3.0 tRNA modification GTPase (NCBI) compare
b1252 tonB -0.7 -1.7 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b1144 ymfJ -0.7 -1.6 orf, hypothetical protein (VIMSS) compare
b1595 ynfL -0.7 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0990 cspG -0.7 -1.1 DNA-binding transcriptional regulator (NCBI) compare
b1959 yedA -0.7 -1.8 predicted inner membrane protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in stress experiments

For stress syringaldehyde across organisms