Experiment set2IT073 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Phenylalanine carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_1010 -6.2 -6.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_362 -6.2 -8.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_5001 -5.9 -8.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_1540 -5.8 -8.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_1472 -5.6 -5.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_3947 -5.6 -5.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_3948 -5.5 -6.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_2046 -5.5 -6.6 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_149 -5.5 -8.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_172 -5.4 -9.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_2842 -5.4 -6.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1539 -5.4 -9.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_5000 -5.4 -16.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_2032 -5.4 -3.7 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_644 -5.3 -9.5 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_359 -5.1 -10.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_3945 -5.1 -13.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_1368 -5.1 -6.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_951 -5.1 -15.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_1739 -5.1 -11.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_845 -5.1 -8.4 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_757 -5.0 -4.4 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_358 -5.0 -4.6 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_913 -4.9 -8.2 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_1603 -4.9 -3.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_2034 -4.9 -3.3 hypothetical protein compare
PfGW456L13_1749 -4.8 -3.3 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_1233 -4.8 -3.3 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1524 -4.8 -7.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_2656 -4.7 -9.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1538 -4.7 -12.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_361 -4.7 -13.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_4961 -4.7 -8.3 Fumarylacetoacetase (EC 3.7.1.2) compare
PfGW456L13_727 -4.6 -11.5 LysR family transcriptional regulator PA5437 compare
PfGW456L13_793 -4.6 -4.4 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_854 -4.5 -3.1 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_1615 -4.3 -2.7 Probable transmembrane protein compare
PfGW456L13_302 -4.3 -8.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_728 -4.3 -16.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_2552 -4.2 -8.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_2230 -4.2 -9.5 Cys regulon transcriptional activator CysB compare
PfGW456L13_2843 -4.1 -11.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_303 -4.0 -3.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_275 -4.0 -2.7 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_4859 -3.9 -4.6 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_3179 -3.9 -5.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_1972 -3.8 -3.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_4125 -3.8 -4.0 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_565 -3.7 -7.1 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_4854 -3.7 -11.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_943 -3.7 -8.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_3894 -3.7 -3.2 Integration host factor alpha subunit compare
PfGW456L13_2035 -3.7 -13.4 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_3934 -3.6 -13.9 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_3940 -3.6 -13.1 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1153 -3.5 -14.1 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_4026 -3.5 -3.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_2935 -3.5 -12.4 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (from data) conserved
PfGW456L13_5008 -3.5 -3.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_1222 -3.5 -6.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_50 -3.4 -11.3 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_1007 -3.4 -13.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_276 -3.4 -2.1 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_1217 -3.3 -18.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_729 -3.3 -10.7 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_4009 -3.2 -14.2 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_566 -3.2 -9.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_4960 -3.2 -6.3 Maleylacetoacetate isomerase (EC 5.2.1.2) @ Glutathione S-transferase, zeta (EC 2.5.1.18) compare
PfGW456L13_4170 -3.2 -8.7 Isochorismatase (EC 3.3.2.1) compare
PfGW456L13_1221 -3.1 -13.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1139 -3.1 -12.1 Malate synthase G (EC 2.3.3.9) compare
PfGW456L13_4962 -3.1 -11.5 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) conserved
PfGW456L13_4229 -3.0 -14.0 Long-chain fatty acid transport protein compare
PfGW456L13_3398 -3.0 -5.4 Transcriptional regulator, TetR family compare
PfGW456L13_2237 -2.9 -3.6 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4165 -2.9 -4.5 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_4671 -2.9 -10.7 Transcriptional regulator, Cro/CI family compare
PfGW456L13_973 -2.8 -12.2 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_990 -2.7 -4.8 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_1220 -2.7 -8.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_656 -2.6 -5.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_4393 -2.6 -9.2 Phenylalanine hydroxylase transcriptional activator PhhR conserved
PfGW456L13_2872 -2.6 -13.9 Acetoacetyl-CoA synthetase (EC 6.2.1.16) compare
PfGW456L13_1006 -2.5 -5.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_2597 -2.5 -8.4 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
PfGW456L13_5150 -2.5 -4.5 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_150 -2.5 -1.8 hypothetical protein compare
PfGW456L13_2553 -2.4 -10.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_2875 -2.4 -13.5 Sigma-54 dependent transcriptional regulator compare
PfGW456L13_1363 -2.4 -5.7 Rare lipoprotein A precursor compare
PfGW456L13_944 -2.3 -12.6 D-2-hydroxyglutarate dehydrogenase compare
PfGW456L13_1523 -2.3 -4.5 Poly(A) polymerase (EC 2.7.7.19) compare
PfGW456L13_5086 -2.3 -5.1 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_2633 -2.3 -13.3 Isocitrate lyase (EC 4.1.3.1) compare
PfGW456L13_3544 -2.2 -8.8 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
PfGW456L13_784 -2.2 -7.5 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_1735 -2.2 -4.9 Glycerol uptake facilitator protein compare
PfGW456L13_2551 -2.2 -4.9 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_1009 -2.2 -3.3 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_1845 -2.2 -4.9 Cold shock protein CspC compare
PfGW456L13_2885 -2.1 -8.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
PfGW456L13_1863 -2.0 -9.1 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_4992 -2.0 -13.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_4993 -2.0 -11.8 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
PfGW456L13_1852 -1.9 -7.4 Holliday junction DNA helicase RuvA compare
PfGW456L13_2424 -1.9 -3.0 Phenylacetate-CoA oxygenase, PaaJ subunit compare
PfGW456L13_1219 -1.9 -5.8 hypothetical protein compare
PfGW456L13_4145 -1.9 -9.1 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1860 -1.9 -8.6 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
PfGW456L13_4740 -1.9 -11.2 Phosphoenolpyruvate carboxylase (EC 4.1.1.31) compare
PfGW456L13_5005 -1.9 -5.5 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_329 -1.9 -4.5 Histidine utilization repressor compare
PfGW456L13_4394 -1.9 -6.6 Phenylalanine 4-monooxygenase (EC 1.14.16.1) (from data) conserved
PfGW456L13_2651 -1.9 -5.5 Cell division protein FtsK compare
PfGW456L13_350 -1.8 -5.1 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_3704 -1.8 -3.6 Transcriptional regulator RpiR in protein degradation cluster compare
PfGW456L13_1050 -1.8 -9.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_2556 -1.8 -3.9 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
PfGW456L13_360 -1.8 -2.0 FIG00956267: hypothetical protein compare
PfGW456L13_4254 -1.8 -5.5 FIG00955360: hypothetical protein compare
PfGW456L13_953 -1.8 -10.8 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_5082 -1.7 -5.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_874 -1.7 -13.8 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_1198 -1.7 -5.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
PfGW456L13_4041 -1.7 -2.7 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_4396 -1.7 -5.7 tyrosine aminotransferase (EC 2.6.1.57) (from data) conserved
PfGW456L13_949 -1.7 -10.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_1842 -1.7 -8.4 Outer membrane porin, OprD family compare
PfGW456L13_5006 -1.7 -2.8 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_1655 -1.7 -2.5 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_4898 -1.7 -2.1 Inner membrane protein compare
PfGW456L13_4999 -1.7 -8.9 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_1838 -1.7 -5.6 Sensory box histidine kinase compare
PfGW456L13_4207 -1.6 -7.2 Periplasmic protease compare
PfGW456L13_5060 -1.6 -5.1 Peptide chain release factor 3 compare
PfGW456L13_773 -1.5 -5.7 Hydrogen peroxide-inducible genes activator compare
PfGW456L13_4836 -1.5 -8.1 Transglycosylase, Slt family compare
PfGW456L13_2190 -1.5 -5.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
PfGW456L13_5017 -1.5 -3.3 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_2873 -1.5 -4.7 D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) compare
PfGW456L13_5067 -1.5 -9.2 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_2029 -1.5 -10.2 BarA sensory histidine kinase (= VarS = GacS) compare
PfGW456L13_4512 -1.5 -6.6 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_4012 -1.5 -2.6 VacJ-like lipoprotein precursor compare
PfGW456L13_1625 -1.5 -3.0 FIG00958649: hypothetical protein compare
PfGW456L13_1169 -1.5 -8.5 Coenzyme PQQ synthesis protein F compare
PfGW456L13_2108 -1.5 -6.2 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
PfGW456L13_3905 -1.4 -3.4 hypothetical protein compare
PfGW456L13_1580 -1.4 -6.5 FIG140336: TPR domain protein compare
PfGW456L13_355 -1.4 -4.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_2436 -1.4 -4.5 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_3872 -1.4 -5.6 Transcriptional regulator, AraC family compare
PfGW456L13_1975 -1.4 -3.3 Succinylarginine dihydrolase (EC 3.5.3.23) compare
PfGW456L13_3305 -1.4 -5.3 BatD compare
PfGW456L13_843 -1.4 -2.8 Protein of unknown function DUF484 compare
PfGW456L13_3304 -1.3 -5.2 TPR domain protein in aerotolerance operon compare
PfGW456L13_3836 -1.3 -5.6 Decarboxylase family protein compare
PfGW456L13_3808 -1.3 -2.4 Predicted transcriptional regulator of NADH dehydrogenase, Rrf2 family compare
PfGW456L13_427 -1.3 -2.2 Two-component system response regulator OmpR compare
PfGW456L13_2221 -1.3 -8.8 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_1386 -1.3 -11.2 Sensor histidine kinase compare
PfGW456L13_2012 -1.3 -8.3 Sensor protein PhoQ (EC 2.7.13.3) compare
PfGW456L13_1963 -1.3 -11.3 Acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
PfGW456L13_2826 -1.2 -2.2 hypothetical protein compare
PfGW456L13_1854 -1.2 -3.5 4-hydroxybenzoyl-CoA thioesterase family active site compare
PfGW456L13_155 -1.2 -4.1 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
PfGW456L13_1525 -1.2 -6.1 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
PfGW456L13_1020 -1.2 -5.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_4668 -1.2 -4.3 RecA protein compare
PfGW456L13_1370 -1.2 -3.0 FIG00957593: hypothetical protein compare
PfGW456L13_351 -1.2 -3.0 Glutaredoxin 3 (Grx3) compare
PfGW456L13_2984 -1.2 -3.7 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
PfGW456L13_2874 -1.2 -3.3 D-beta-hydroxybutyrate permease compare
PfGW456L13_1763 -1.1 -4.2 FxsA protein compare
PfGW456L13_2244 -1.1 -6.8 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase II (EC 2.5.1.54) conserved
PfGW456L13_3300 -1.1 -7.4 MoxR-like ATPase in aerotolerance operon compare
PfGW456L13_2426 -1.1 -2.1 Phenylacetate-CoA oxygenase, PaaH subunit compare
PfGW456L13_2924 -1.1 -4.7 Glutathione reductase (EC 1.8.1.7) compare
PfGW456L13_2632 -1.1 -3.1 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_1853 -1.1 -2.6 Holliday junction DNA helicase RuvB compare
PfGW456L13_705 -1.1 -1.1 FIG00953800: hypothetical protein compare
PfGW456L13_1212 -1.1 -8.6 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
PfGW456L13_283 -1.1 -6.1 NADP-dependent malic enzyme (EC 1.1.1.40) compare
PfGW456L13_1453 -1.1 -7.4 Glutathione-regulated potassium-efflux system ATP-binding protein compare
PfGW456L13_5089 -1.1 -1.5 Transcription termination protein NusA compare
PfGW456L13_2184 -1.1 -3.5 putative polysaccharide polymerase compare
PfGW456L13_3303 -1.1 -4.8 BatA (Bacteroides aerotolerance operon) compare
PfGW456L13_4451 -1.0 -4.6 ATP-dependent RNA helicase SrmB compare
PfGW456L13_3937 -1.0 -1.6 DedD protein compare
PfGW456L13_426 -1.0 -6.0 Osmolarity sensory histidine kinase EnvZ compare
PfGW456L13_769 -1.0 -1.3 DNA-binding protein HU-alpha compare
PfGW456L13_1147 -1.0 -7.6 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_2189 -1.0 -5.7 UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid transferase compare
PfGW456L13_1851 -1.0 -3.6 Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) compare
PfGW456L13_352 -1.0 -3.0 FIG136845: Rhodanese-related sulfurtransferase compare
PfGW456L13_1612 -1.0 -3.0 FIG00956396: hypothetical protein compare
PfGW456L13_911 -1.0 -6.3 Adenylate cyclase (EC 4.6.1.1) compare
PfGW456L13_4216 -1.0 -5.1 DNA recombination-dependent growth factor C compare
PfGW456L13_1213 -1.0 -3.2 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
PfGW456L13_4042 -1.0 -2.4 FIG00953628: hypothetical protein compare


Specific Phenotypes

For 13 genes in this experiment

For carbon source L-Phenylalanine in Pseudomonas fluorescens GW456-L13

For carbon source L-Phenylalanine across organisms