Experiment set2IT066 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Asparagine carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_362 -6.8 -6.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_973 -6.7 -6.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_358 -6.6 -4.5 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_361 -6.5 -9.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_742 -6.2 -6.0 Aspartate ammonia-lyase (EC 4.3.1.1) compare
PfGW456L13_149 -6.2 -6.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_1007 -6.2 -6.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1222 -6.1 -4.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_1368 -6.0 -4.1 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_2046 -6.0 -4.1 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_3934 -6.0 -10.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_303 -6.0 -4.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_5001 -5.9 -7.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_951 -5.9 -10.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_172 -5.9 -8.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_3940 -5.8 -7.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1540 -5.8 -8.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_3945 -5.8 -6.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_2842 -5.7 -5.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_845 -5.6 -3.9 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_1539 -5.6 -8.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_1217 -5.5 -22.3 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_3948 -5.4 -6.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_1739 -5.4 -8.2 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_1050 -5.4 -8.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_913 -5.4 -6.4 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_2032 -5.3 -3.7 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_5000 -5.3 -16.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_1221 -5.3 -14.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_743 -5.2 -6.2 Transcriptional regulator compare
PfGW456L13_359 -5.2 -10.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_3947 -5.1 -6.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_644 -5.1 -9.8 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_1010 -5.1 -8.5 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_2656 -5.1 -7.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1863 -5.0 -9.0 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_2843 -4.9 -10.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_1538 -4.9 -11.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1603 -4.8 -3.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_565 -4.8 -4.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_5082 -4.7 -4.6 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_2176 -4.7 -8.5 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_1524 -4.7 -7.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_4125 -4.7 -4.5 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_420 -4.6 -3.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_302 -4.6 -7.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_1749 -4.5 -4.4 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_854 -4.5 -3.1 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_1472 -4.4 -7.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_1233 -4.4 -4.2 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1604 -4.4 -8.8 hypothetical protein compare
PfGW456L13_1615 -4.3 -2.6 Probable transmembrane protein compare
PfGW456L13_4253 -4.3 -5.8 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_2230 -4.2 -10.8 Cys regulon transcriptional activator CysB compare
PfGW456L13_283 -4.2 -12.0 NADP-dependent malic enzyme (EC 1.1.1.40) compare
PfGW456L13_1006 -4.2 -5.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_4772 -4.1 -10.8 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 2 (from data) conserved
PfGW456L13_779 -4.0 -13.2 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_275 -4.0 -2.7 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_5008 -4.0 -2.7 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_1147 -3.9 -14.8 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_4775 -3.9 -9.3 Two component, Sigma-54 Specific, central transcriptional regulator of acidic amino acid uptake compare
PfGW456L13_793 -3.8 -4.8 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_5067 -3.7 -12.1 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_566 -3.7 -9.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_656 -3.7 -5.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_50 -3.6 -11.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_1735 -3.5 -3.4 Glycerol uptake facilitator protein compare
PfGW456L13_4770 -3.5 -12.0 ABC transporter for L-Asparagine and possibly other L-amino acids, periplasmic substrate-binding component (from data) conserved
PfGW456L13_1813 -3.5 -8.4 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_276 -3.4 -2.1 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_943 -3.4 -7.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_4859 -3.4 -5.6 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_4026 -3.3 -3.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_4854 -3.3 -8.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_4774 -3.3 -15.3 Signal transduction histidine kinase regulating C4-dicarboxylate transport system (EC 2.7.13.3) conserved
PfGW456L13_3179 -3.3 -5.3 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4771 -3.1 -7.8 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 1 (from data) conserved
PfGW456L13_1151 -3.1 -11.4 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_2632 -3.1 -5.0 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_1889 -3.1 -4.1 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_2551 -3.0 -5.3 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_740 -3.0 -10.2 L-asparaginase (EC 3.5.1.1) (from data) conserved
PfGW456L13_1972 -3.0 -3.4 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_1220 -3.0 -6.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1148 -2.9 -15.9 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_2103 -2.8 -6.1 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_726 -2.8 -7.4 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_4769 -2.7 -3.5 hypothetical protein compare
PfGW456L13_756 -2.7 -6.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_5150 -2.7 -4.4 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_1044 -2.7 -13.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_4088 -2.6 -4.2 Transcriptional regulator, GntR family compare
PfGW456L13_1150 -2.6 -14.3 Biotin synthesis protein BioC compare
PfGW456L13_355 -2.6 -6.4 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_4165 -2.6 -4.1 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_430 -2.5 -9.8 Glutamate--cysteine ligase (EC 6.3.2.2) compare
PfGW456L13_2556 -2.5 -4.5 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
PfGW456L13_1845 -2.4 -4.8 Cold shock protein CspC compare
PfGW456L13_4999 -2.4 -11.3 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_2597 -2.4 -5.8 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
PfGW456L13_4517 -2.4 -13.5 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_1824 -2.3 -2.0 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_5006 -2.3 -3.0 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_1580 -2.3 -9.4 FIG140336: TPR domain protein compare
PfGW456L13_1838 -2.3 -6.1 Sensory box histidine kinase compare
PfGW456L13_5003 -2.1 -2.7 YrbA protein compare
PfGW456L13_59 -2.1 -7.3 Sensor histidine kinase/response regulator compare
PfGW456L13_5060 -2.1 -5.8 Peptide chain release factor 3 compare
PfGW456L13_4842 -2.1 -3.3 Translation elongation factor LepA compare
PfGW456L13_1009 -2.0 -3.4 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_5005 -1.9 -5.4 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_4882 -1.9 -4.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_2623 -1.9 -3.0 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_3398 -1.9 -4.1 Transcriptional regulator, TetR family compare
PfGW456L13_2237 -1.9 -2.6 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_990 -1.9 -3.5 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_949 -1.9 -9.4 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_2651 -1.8 -4.8 Cell division protein FtsK compare
PfGW456L13_875 -1.8 -5.4 Exopolyphosphatase (EC 3.6.1.11) compare
PfGW456L13_2631 -1.8 -3.3 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_3181 -1.8 -2.9 Organic hydroperoxide resistance protein compare
PfGW456L13_2552 -1.8 -7.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_2436 -1.8 -5.4 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1219 -1.7 -2.5 hypothetical protein compare
PfGW456L13_2084 -1.7 -3.0 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_4992 -1.7 -11.8 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_1984 -1.7 -2.7 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_1363 -1.6 -4.4 Rare lipoprotein A precursor compare
PfGW456L13_4254 -1.6 -7.4 FIG00955360: hypothetical protein compare
PfGW456L13_152 -1.6 -5.0 HflK protein compare
PfGW456L13_1021 -1.6 -4.9 Glutathione synthetase (EC 6.3.2.3) compare
PfGW456L13_753 -1.6 -9.6 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
PfGW456L13_350 -1.5 -4.7 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_1975 -1.5 -3.7 Succinylarginine dihydrolase (EC 3.5.3.23) compare
PfGW456L13_144 -1.5 -5.2 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_4207 -1.5 -6.6 Periplasmic protease compare
PfGW456L13_4243 -1.5 -2.2 Cob(I)alamin adenosyltransferase (EC 2.5.1.17) compare
PfGW456L13_1842 -1.5 -8.5 Outer membrane porin, OprD family compare
PfGW456L13_4451 -1.5 -5.2 ATP-dependent RNA helicase SrmB compare
PfGW456L13_4993 -1.4 -8.7 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
PfGW456L13_3445 -1.3 -2.7 hypothetical protein compare
PfGW456L13_3305 -1.3 -4.4 BatD compare
PfGW456L13_5017 -1.3 -3.3 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
PfGW456L13_2763 -1.3 -2.6 putative tellurium resistance protein compare
PfGW456L13_4113 -1.3 -7.8 FIG137360: hypothetical protein compare
PfGW456L13_151 -1.3 -3.3 HflC protein compare
PfGW456L13_1852 -1.3 -4.6 Holliday junction DNA helicase RuvA compare
PfGW456L13_67 -1.3 -5.1 Cobalamin biosynthesis protein CobG compare
PfGW456L13_1655 -1.3 -1.6 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_4042 -1.3 -1.9 FIG00953628: hypothetical protein compare
PfGW456L13_5048 -1.3 -2.5 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_2833 -1.3 -3.8 hypothetical protein compare
PfGW456L13_3591 -1.3 -2.1 hypothetical protein compare
PfGW456L13_994 -1.3 -2.9 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
PfGW456L13_787 -1.3 -4.8 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_1628 -1.3 -5.4 ATPase, AFG1 family compare
PfGW456L13_4545 -1.2 -2.3 Integral membrane protein compare
PfGW456L13_1029 -1.2 -1.6 Triphosphoribosyl-dephospho-CoA synthetase (EC 2.7.8.25) compare
PfGW456L13_1537 -1.2 -2.4 Hypothetical protein YqcC (clustered with tRNA pseudouridine synthase C) compare
PfGW456L13_2908 -1.2 -1.8 hypothetical protein compare
PfGW456L13_5121 -1.2 -1.2 hypothetical protein compare
PfGW456L13_1017 -1.2 -1.8 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
PfGW456L13_1848 -1.2 -2.1 hypothetical protein compare
PfGW456L13_139 -1.2 -1.5 LSU ribosomal protein L9p compare
PfGW456L13_3941 -1.2 -6.9 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
PfGW456L13_1130 -1.2 -2.8 Glutathione S-transferase family protein compare
PfGW456L13_155 -1.1 -4.2 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
PfGW456L13_1574 -1.1 -3.3 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_3808 -1.1 -2.4 Predicted transcriptional regulator of NADH dehydrogenase, Rrf2 family compare
PfGW456L13_4033 -1.1 -1.2 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
PfGW456L13_360 -1.1 -1.3 FIG00956267: hypothetical protein compare
PfGW456L13_591 -1.1 -4.7 Cytochrome c4 compare
PfGW456L13_5112 -1.1 -1.2 tmRNA-binding protein SmpB compare
PfGW456L13_2636 -1.1 -4.5 FIG002776: hypothetical protein compare
PfGW456L13_3704 -1.1 -2.8 Transcriptional regulator RpiR in protein degradation cluster compare
PfGW456L13_4668 -1.1 -3.1 RecA protein compare
PfGW456L13_4883 -1.1 -3.8 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
PfGW456L13_1382 -1.0 -5.6 FOG: TPR repeat, SEL1 subfamily compare
PfGW456L13_1020 -1.0 -4.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_1525 -1.0 -5.7 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
PfGW456L13_5046 -1.0 -4.2 Predicted D-glucarate or D-galactorate regulator, GntR family compare
PfGW456L13_4236 -1.0 -2.3 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
PfGW456L13_1520 -1.0 -3.0 Pantoate--beta-alanine ligase (EC 6.3.2.1) compare
PfGW456L13_4424 -1.0 -3.4 FIG00953416: hypothetical protein compare
PfGW456L13_741 -1.0 -8.6 sodium/alanine transporter compare
PfGW456L13_2385 -1.0 -1.7 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
PfGW456L13_4108 -1.0 -1.2 CrfX protein compare
PfGW456L13_4242 -1.0 -5.8 Cobyrinic acid A,C-diamide synthase compare
PfGW456L13_4618 -1.0 -3.1 Outer membrane lipoprotein compare
PfGW456L13_3634 -1.0 -2.9 Transcriptional regulator compare
PfGW456L13_4507 -1.0 -1.3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_944 -1.0 -6.5 D-2-hydroxyglutarate dehydrogenase compare
PfGW456L13_754 -1.0 -5.7 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
PfGW456L13_4580 -1.0 -3.9 Multidrug efflux RND membrane fusion protein MexC compare
PfGW456L13_2273 -1.0 -3.2 Molybdenum cofactor biosynthesis protein MoaB compare
PfGW456L13_1982 -1.0 -1.4 Carbon storage regulator compare
PfGW456L13_2107 -0.9 -3.5 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
PfGW456L13_757 -0.9 -1.4 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_3409 -0.9 -1.9 Transcriptional regulator, IclR family compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source L-Asparagine in Pseudomonas fluorescens GW456-L13

For carbon source L-Asparagine across organisms