Experiment set2IT065 for Escherichia coli BW25113

Compare to:

LB with Carbenicillin disodium salt 0.008 mg/ml

200 most important genes:

  gene name fitness t score description  
b0920 ycbC -4.3 -4.1 conserved inner membrane protein (NCBI) compare
b1105 ycfM -4.2 -2.9 predicted outer membrane lipoprotein (NCBI) compare
b4392 slt -4.0 -10.0 soluble lytic murein transglycosylase (VIMSS) conserved
b0149 mrcB -3.5 -5.4 penicillin-binding protein 1b (NCBI) compare
b1192 ldcA -3.4 -4.0 L,D-carboxypeptidase A (NCBI) compare
b2567 rnc -3.3 -2.2 ribonuclease III (NCBI) compare
b0957 ompA -3.2 -4.3 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b0463 acrA -3.2 -8.5 multidrug efflux system (NCBI) compare
b2528 iscA -2.9 -1.9 iron-sulfur cluster assembly protein (NCBI) compare
b2330 yfcB -2.8 -1.9 putative adenine-specific methylase (VIMSS) compare
b0433 ampG -2.8 -12.2 muropeptide transporter (NCBI) conserved
b0737 tolQ -2.8 -2.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3035 tolC -2.8 -7.9 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0741 pal -2.7 -3.6 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0738 tolR -2.7 -1.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3229 sspA -2.7 -3.6 stringent starvation protein A (NCBI) compare
b0739 tolA -2.5 -3.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2470 acrD -2.5 -10.0 aminoglycoside/multidrug efflux system (NCBI) compare
b0434 yajG -2.4 -6.8 putative polymerase/proteinase (VIMSS) compare
b3163 nlpI -2.3 -4.8 hypothetical protein (NCBI) compare
b1103 ycfF -2.3 -1.5 orf, hypothetical protein (VIMSS) compare
b0462 acrB -2.2 -12.0 multidrug efflux system protein (NCBI) compare
b3871 bipA -2.2 -10.5 GTP-binding protein (NCBI) compare
b2617 smpA -2.2 -3.4 small membrane protein A (VIMSS) compare
b0605 ahpC -2.2 -6.2 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b4375 prfC -2.1 -4.8 peptide chain release factor 3 (NCBI) compare
b2553 glnB -2.1 -4.5 regulatory protein P-II for glutamine synthetase (NCBI) compare
b0051 ksgA -2.1 -5.5 dimethyladenosine transferase (NCBI) compare
b1863 ruvC -2.1 -3.5 Holliday junction resolvase (NCBI) compare
b4202 rpsR -2.0 -2.3 30S ribosomal protein S18 (NCBI) compare
b3183 obgE -2.0 -1.9 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4172 hfq -2.0 -1.9 RNA-binding protein Hfq (NCBI) compare
b0429 cyoD -2.0 -3.9 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b0436 tig -2.0 -7.4 trigger factor (NCBI) compare
b3613 yibP -2.0 -5.6 putative membrane protein (VIMSS) compare
b3728 pstS -2.0 -4.4 phosphate transporter subunit (NCBI) compare
b3636 rpmG -2.0 -2.2 50S ribosomal protein L33 (NCBI) compare
b0740 tolB -1.9 -3.2 translocation protein TolB precursor (NCBI) compare
b3462 ftsX -1.9 -4.6 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b1129 phoQ -1.9 -6.7 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b2494 yfgC -1.9 -6.5 predicted peptidase (NCBI) compare
b1130 phoP -1.9 -6.1 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b0632 dacA -1.9 -5.5 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b0145 dksA -1.8 -3.2 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4480 hdfR -1.8 -5.6 transcriptional regulator HdfR (NCBI) compare
b3131 agaR -1.8 -3.9 DNA-binding transcriptional dual regulator (NCBI) compare
b3784 rfe -1.8 -11.1 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b2576 srmB -1.8 -3.0 ATP-dependent RNA helicase (NCBI) compare
b3226 yhcK -1.8 -5.1 putative FADA-type transcriptional regulator (VIMSS) compare
b2512 yfgL -1.8 -3.9 protein assembly complex, lipoprotein component (NCBI) compare
b4441 glmY -1.8 -1.9 sRNA activator of glmS mRNA (RefSeq) compare
b3933 ftsN -1.8 -9.9 essential cell division protein (NCBI) compare
b3725 pstB -1.7 -2.3 phosphate transporter subunit (NCBI) compare
b0431 cyoB -1.7 -7.4 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3839 tatC -1.7 -8.4 TatABCE protein translocation system subunit (NCBI) compare
b2215 ompC -1.6 -7.2 outer membrane porin protein C (NCBI) compare
b2701 mltB -1.6 -4.8 membrane-bound lytic murein transglycosylase B (NCBI) compare
b3807 cyaY -1.6 -6.3 frataxin-like protein (NCBI) compare
b2906 visC -1.6 -5.1 hypothetical protein (NCBI) compare
b2279 nuoK -1.6 -2.3 NADH dehydrogenase subunit K (NCBI) compare
b3463 ftsE -1.6 -3.7 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1286 rnb -1.6 -3.0 exoribonuclease II (NCBI) compare
b3414 gntY -1.6 -5.4 predicted gluconate transport associated protein (NCBI) compare
b3935 priA -1.6 -2.9 primosome assembly protein PriA (NCBI) compare
b2911 ssrS -1.5 -1.4 6S regulatory RNA (NCBI) compare
b3164 pnp -1.5 -2.6 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1576 ydfD -1.5 -2.5 Qin prophage; predicted protein (NCBI) compare
b3425 glpE -1.5 -6.1 thiosulfate sulfurtransferase (NCBI) compare
b2642 yfjW -1.5 -2.7 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3912 cpxR -1.5 -7.5 DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) compare
b2937 speB -1.5 -5.9 agmatinase (NCBI) compare
b3406 greB -1.4 -4.5 transcription elongation factor GreB (NCBI) compare
b0249 ykfF -1.4 -2.0 CP4-6 prophage; predicted protein (NCBI) compare
b0212 gloB -1.4 -2.2 predicted hydroxyacylglutathione hydrolase (NCBI) compare
b2699 recA -1.4 -1.4 recombinase A (NCBI) compare
b0081 mraZ -1.4 -4.0 hypothetical protein (NCBI) compare
b2055 wcaE -1.4 -2.0 predicted glycosyl transferase (NCBI) compare
b0998 torD -1.4 -1.3 chaperone protein TorD (NCBI) compare
b3884 yihW -1.4 -4.9 putative DEOR-type transcriptional regulator (VIMSS) compare
b3787 rffD -1.4 -8.2 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b0088 murD -1.4 -2.0 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1830 prc -1.4 -3.9 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b4042 dgkA -1.4 -3.0 diacylglycerol kinase (NCBI) compare
b3199 yrbK -1.4 -2.4 hypothetical protein (NCBI) compare
b1332 ynaJ -1.4 -1.2 predicted inner membrane protein (NCBI) compare
b2807 ygdD -1.4 -2.9 conserved inner membrane protein (NCBI) compare
b0603 ybdO -1.4 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0623 cspE -1.4 -2.0 cold shock protein E (NCBI) compare
b3341 rpsG -1.3 -1.0 30S ribosomal protein S7 (NCBI) compare
b2896 ygfX -1.3 -4.1 hypothetical protein (NCBI) compare
b3977 tyrU -1.3 -1.3 tRNA-Tyr (NCBI) compare
b1712 ihfA -1.3 -2.4 integration host factor subunit alpha (NCBI) compare
b2830 nudH -1.3 -1.7 dinucleoside polyphosphate hydrolase (NCBI) compare
b3472 b3472 -1.3 -6.1 orf, hypothetical protein (VIMSS) compare
b3792 wzxE -1.3 -6.9 O-antigen translocase (NCBI) compare
b1104 ycfL -1.3 -1.2 hypothetical protein (NCBI) compare
b3764 yifE -1.3 -4.1 hypothetical protein (NCBI) compare
b1540 ydfH -1.3 -0.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b0912 ihfB -1.3 -2.7 integration host factor subunit beta (NCBI) compare
b3863 polA -1.3 -1.2 DNA polymerase I (NCBI) compare
b0430 cyoC -1.3 -2.9 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b3644 yicC -1.3 -4.8 hypothetical protein (NCBI) compare
b1860 ruvB -1.3 -1.4 Holliday junction DNA helicase B (NCBI) compare
b0340 cynS -1.3 -1.8 cyanate hydratase (NCBI) compare
b2510 b2510 -1.3 -3.2 orf, hypothetical protein (VIMSS) compare
b3794 rffM -1.3 -5.0 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b1984 asnW -1.3 -1.2 tRNA-Asn (NCBI) compare
b1101 ptsG -1.3 -6.2 fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) compare
b1109 ndh -1.2 -3.1 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b2350 yfdG -1.2 -3.9 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b3928 yiiU -1.2 -4.8 hypothetical protein (NCBI) compare
b3726 pstA -1.2 -4.7 phosphate transporter subunit (NCBI) compare
b3261 fis -1.2 -2.8 DNA-binding protein Fis (NCBI) compare
b2083 yegZ -1.2 -1.7 orf, hypothetical protein (VIMSS) compare
b0677 nagA -1.2 -3.7 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1347 ydaC -1.2 -1.5 Rac prophage; predicted protein (NCBI) compare
b0053 surA -1.2 -2.9 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2005 yeeV -1.2 -2.8 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system (NCBI) compare
b3616 tdh -1.2 -4.5 L-threonine 3-dehydrogenase (NCBI) compare
b0849 grxA -1.2 -1.9 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) (NCBI) compare
b0427 yajR -1.2 -5.8 putative transport protein (VIMSS) compare
b1730 ydjO -1.2 -2.5 predicted protein (RefSeq) compare
b1658 purR -1.2 -4.1 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3786 rffE -1.1 -7.7 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b1107 nagZ -1.1 -3.1 beta-hexosaminidase (NCBI) compare
b4655 ythA -1.1 -2.0 expressed protein (RefSeq) compare
b1760 ynjH -1.1 -2.1 hypothetical protein (NCBI) compare
b1167 ymgC -1.1 -1.6 hypothetical protein (NCBI) compare
b1390 paaC -1.1 -2.5 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b2659 b2659 -1.1 -1.6 orf, hypothetical protein (VIMSS) compare
b1088 yceD -1.1 -2.5 hypothetical protein (NCBI) compare
b3348 slyX -1.1 -2.7 hypothetical protein (NCBI) compare
b1531 marA -1.1 -2.0 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b0428 cyoE -1.1 -3.7 protoheme IX farnesyltransferase (NCBI) compare
b1634 tppB -1.1 -3.4 putative tripeptide transporter permease (NCBI) compare
b3617 kbl -1.1 -5.2 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b2820 recB -1.1 -1.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0082 mraW -1.1 -2.6 S-adenosyl-methyltransferase (NCBI) compare
b2897 ygfY -1.1 -1.7 hypothetical protein (NCBI) compare
b1569 dicC -1.0 -1.7 Qin prophage; DNA-binding transcriptional regulator for DicB (NCBI) compare
b2188 yejM -1.0 -4.7 predicted hydrolase, inner membrane (NCBI) compare
b3790 rffC -1.0 -3.5 TDP-fucosamine acetyltransferase (RefSeq) compare
b1409 ynbB -1.0 -3.9 predicted CDP-diglyceride synthase (NCBI) compare
b3791 rffA -1.0 -5.3 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1394 paaG -1.0 -1.7 enoyl-CoA hydratase (NCBI) compare
b3504 yhiS -1.0 -2.6 hypothetical protein (RefSeq) compare
b1827 kdgR -1.0 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b0432 cyoA -1.0 -5.3 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b0890 ftsK -1.0 -4.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3237 argR -1.0 -3.0 arginine repressor (NCBI) compare
b0934 ycbM -1.0 -2.2 putative transport system permease protein (VIMSS) compare
b1591 b1591 -1.0 -1.3 putative oxidoreductase component (VIMSS) compare
b2366 dsdA -1.0 -3.5 D-serine dehydratase (NCBI) compare
b0471 ybaB -1.0 -2.3 hypothetical protein (NCBI) compare
b4685 yrbN -1.0 -1.9 expressed protein (RefSeq) compare
b1097 yceG -1.0 -3.2 predicted aminodeoxychorismate lyase (NCBI) compare
b4613 dinQ -0.9 -1.4 Damage inducible, function unknown (RefSeq) compare
b0547 ybcN -0.9 -2.6 DLP12 prophage; predicted protein (NCBI) compare
b1954 dsrA -0.9 -1.6 regulatory antisense RNA (NCBI) compare
b3121 yhaC -0.9 -1.6 hypothetical protein (NCBI) compare
b1144 ymfJ -0.9 -1.7 orf, hypothetical protein (VIMSS) compare
b1323 tyrR -0.9 -2.7 DNA-binding transcriptional dual regulator, tyrosine-binding (NCBI) compare
b1989 asnV -0.9 -1.6 tRNA-Asn (NCBI) compare
b4191 ulaR -0.9 -2.9 DNA-binding transcriptional dual regulator (NCBI) compare
b3096 yqjB -0.9 -1.7 hypothetical protein (NCBI) compare
b2593 yfiH -0.9 -4.8 hypothetical protein (NCBI) compare
b1013 ycdC -0.9 -1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b2804 fucU -0.9 -1.7 L-fucose mutarotase (NCBI) compare
b1639 ydhA -0.9 -1.3 orf, hypothetical protein (VIMSS) compare
b0092 ddlB -0.9 -3.0 D-alanylalanine synthetase (NCBI) compare
b4647 mokA -0.9 -1.4 no description compare
b3097 yqjC -0.9 -2.9 orf, hypothetical protein (VIMSS) compare
b2910 zapA -0.9 -2.9 protein that localizes to the cytokinetic ring (NCBI) compare
b4595 yciY -0.9 -1.0 hypothetical protein (RefSeq) compare
b1259 yciG -0.9 -1.3 orf, hypothetical protein (VIMSS) compare
b1557 cspB -0.9 -1.4 Qin prophage; cold shock protein (NCBI) compare
b1936 intG -0.9 -1.5 predicted defective phage integrase (pseudogene) (RefSeq) compare
b1269 rluB -0.9 -2.2 23S rRNA pseudouridylate synthase (NCBI) compare
b0401 brnQ -0.9 -4.4 predicted branched chain amino acid transporter (LIV-II) (NCBI) compare
b2352 yfdI -0.9 -2.0 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b1085 b1085 -0.8 -1.4 orf, hypothetical protein (VIMSS) compare
b2136 yohD -0.8 -1.7 orf, hypothetical protein (VIMSS) compare
b1308 pspE -0.8 -2.4 thiosulfate:cyanide sulfurtransferase (rhodanese) (NCBI) compare
b4208 cycA -0.8 -4.7 D-alanine/D-serine/glycine transporter (NCBI) compare
b1847 yebF -0.8 -1.2 predicted protein (RefSeq) compare
b2829 ptsP -0.8 -4.8 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b4509 ylcG -0.8 -2.0 DLP12 prophage; predicted protein (NCBI) compare
b1499 ydeO -0.8 -1.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1861 ruvA -0.8 -1.2 Holliday junction DNA helicase motor protein (NCBI) compare
b4171 miaA -0.8 -3.0 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3205 yhbJ -0.8 -2.3 hypothetical protein (NCBI) compare
b1358 ydaT -0.8 -1.2 Rac prophage; predicted protein (NCBI) compare
b1992 cobS -0.8 -1.5 cobalamin synthase (NCBI) compare
b4206 ytfB -0.8 -4.3 orf, hypothetical protein (VIMSS) compare
b4503 yafF -0.8 -1.3 no description compare
b0028 fkpB -0.8 -2.2 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare
b1433 b1433 -0.8 -2.4 putative membrane transport protein (VIMSS) compare
b0500 ybbD -0.8 -1.3 hypothetical protein (RefSeq) compare
b2297 pta -0.8 -1.0 phosphate acetyltransferase (NCBI) compare
b0722 sdhD -0.8 -2.3 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare


Specific Phenotypes

For 21 genes in this experiment

For stress Carbenicillin disodium salt in Escherichia coli BW25113

For stress Carbenicillin disodium salt across organisms