Experiment set2IT064 for Pseudomonas fluorescens GW456-L13

Compare to:

L-Malic acid disodium salt monohydrate carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_1222 -5.8 -4.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_1368 -5.7 -3.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_3940 -5.4 -9.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_845 -4.8 -7.4 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_427 -4.8 -2.6 Two-component system response regulator OmpR compare
PfGW456L13_358 -4.8 -2.6 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_3934 -4.7 -12.9 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_1010 -4.7 -9.2 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_4026 -4.6 -2.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_2046 -4.6 -8.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_1050 -4.5 -10.3 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_1221 -4.4 -14.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1217 -4.4 -18.4 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_3948 -4.4 -8.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_565 -4.3 -5.1 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_913 -4.2 -8.1 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_1749 -4.2 -4.1 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_793 -4.2 -4.1 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_3945 -4.2 -13.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_854 -4.2 -2.9 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_1472 -4.2 -6.9 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_1739 -4.1 -13.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_1539 -4.1 -12.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_1007 -4.1 -11.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_149 -3.9 -6.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_1006 -3.9 -5.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_3947 -3.8 -6.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1233 -3.7 -5.1 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_275 -3.7 -2.5 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_5008 -3.7 -2.5 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_4165 -3.6 -3.5 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_172 -3.6 -10.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_2843 -3.6 -10.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_1603 -3.6 -3.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_1540 -3.5 -13.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_5011 -3.4 -2.9 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
PfGW456L13_1524 -3.3 -8.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_276 -3.3 -1.5 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_1538 -3.3 -12.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1615 -3.3 -1.9 Probable transmembrane protein compare
PfGW456L13_1140 -3.2 -1.4 Glycine cleavage system transcriptional antiactivator GcvR compare
PfGW456L13_1363 -3.2 -7.3 Rare lipoprotein A precursor compare
PfGW456L13_2237 -3.2 -3.6 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2084 -3.2 -2.8 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_566 -3.2 -6.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_2496 -3.1 -1.8 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_2842 -3.1 -6.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1735 -3.0 -3.6 Glycerol uptake facilitator protein compare
PfGW456L13_943 -3.0 -5.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_5089 -3.0 -1.6 Transcription termination protein NusA compare
PfGW456L13_4012 -3.0 -2.8 VacJ-like lipoprotein precursor compare
PfGW456L13_1889 -3.0 -4.7 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_4854 -2.9 -10.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_4859 -2.8 -5.0 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_359 -2.7 -8.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_50 -2.7 -9.1 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_2631 -2.7 -3.9 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_951 -2.7 -11.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_1853 -2.6 -4.2 Holliday junction DNA helicase RuvB compare
PfGW456L13_1655 -2.6 -3.2 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_621 -2.4 -4.3 hypothetical protein compare
PfGW456L13_644 -2.4 -6.1 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_5150 -2.4 -2.9 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_5001 -2.4 -8.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_4125 -2.4 -2.8 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_362 -2.4 -5.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_1153 -2.4 -10.7 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_5003 -2.3 -2.6 YrbA protein compare
PfGW456L13_2651 -2.3 -4.8 Cell division protein FtsK compare
PfGW456L13_361 -2.3 -10.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_1854 -2.3 -2.7 4-hydroxybenzoyl-CoA thioesterase family active site compare
PfGW456L13_3181 -2.2 -2.8 Organic hydroperoxide resistance protein compare
PfGW456L13_2551 -2.2 -3.4 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_2656 -2.2 -7.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_355 -2.2 -5.4 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_2035 -2.2 -9.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_1580 -2.2 -7.9 FIG140336: TPR domain protein compare
PfGW456L13_5082 -2.1 -5.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_2981 -2.1 -1.3 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_4671 -2.1 -9.3 Transcriptional regulator, Cro/CI family compare
PfGW456L13_2633 -2.1 -11.5 Isocitrate lyase (EC 4.1.3.1) compare
PfGW456L13_5000 -2.1 -10.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_5060 -2.1 -5.1 Peptide chain release factor 3 compare
PfGW456L13_4207 -2.0 -6.5 Periplasmic protease compare
PfGW456L13_2553 -2.0 -7.1 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_1220 -2.0 -7.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_3309 -2.0 -1.7 Glutathione S-transferase family protein compare
PfGW456L13_2424 -2.0 -2.2 Phenylacetate-CoA oxygenase, PaaJ subunit compare
PfGW456L13_1984 -1.9 -2.5 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_151 -1.9 -3.7 HflC protein compare
PfGW456L13_2552 -1.9 -6.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_420 -1.9 -1.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_3848 -1.9 -2.2 Predicted secretion system X DNA-binding regulator compare
PfGW456L13_4401 -1.9 -2.7 Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_769 -1.9 -1.3 DNA-binding protein HU-alpha compare
PfGW456L13_302 -1.9 -3.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_5006 -1.9 -2.3 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_5086 -1.9 -4.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_4513 -1.8 -2.3 HtrA protease/chaperone protein compare
PfGW456L13_66 -1.8 -1.9 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
PfGW456L13_1205 -1.8 -6.7 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_5005 -1.7 -4.3 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_2034 -1.7 -2.4 hypothetical protein compare
PfGW456L13_5121 -1.7 -1.0 hypothetical protein compare
PfGW456L13_1963 -1.7 -13.9 Acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
PfGW456L13_1139 -1.7 -7.8 Malate synthase G (EC 2.3.3.9) compare
PfGW456L13_3179 -1.7 -2.7 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_4253 -1.6 -3.6 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_1842 -1.6 -8.6 Outer membrane porin, OprD family compare
PfGW456L13_1852 -1.6 -4.2 Holliday junction DNA helicase RuvA compare
PfGW456L13_4009 -1.6 -7.1 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_1574 -1.6 -2.7 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_656 -1.6 -3.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_2632 -1.6 -2.3 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_990 -1.5 -2.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_4507 -1.5 -2.0 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_1625 -1.5 -2.2 FIG00958649: hypothetical protein compare
PfGW456L13_4882 -1.5 -2.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_3894 -1.5 -1.4 Integration host factor alpha subunit compare
PfGW456L13_1838 -1.5 -4.4 Sensory box histidine kinase compare
PfGW456L13_4254 -1.4 -3.7 FIG00955360: hypothetical protein compare
PfGW456L13_3524 -1.4 -7.1 FIG00443700: hypothetical protein compare
PfGW456L13_4842 -1.4 -2.5 Translation elongation factor LepA compare
PfGW456L13_4145 -1.4 -6.0 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_4337 -1.4 -1.6 Flagellar biosynthesis protein FliR compare
PfGW456L13_3525 -1.4 -3.0 ABC transporter, ATP-binding protein compare
PfGW456L13_3526 -1.4 -6.5 ABC transporter permease protein compare
PfGW456L13_296 -1.4 -2.2 Polyhydroxyalkanoate granule-associated protein PhaF compare
PfGW456L13_2984 -1.4 -3.3 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
PfGW456L13_150 -1.4 -2.2 hypothetical protein compare
PfGW456L13_1863 -1.4 -4.5 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_4679 -1.4 -4.1 tRNA pseudouridine 13 synthase (EC 4.2.1.-) compare
PfGW456L13_3887 -1.3 -3.5 cell morphology protein compare
PfGW456L13_1644 -1.3 -2.4 Cell division protein MraZ compare
PfGW456L13_1147 -1.3 -6.9 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_2955 -1.3 -1.6 RND efflux system, membrane fusion protein CmeA compare
PfGW456L13_4155 -1.3 -3.2 Spermidine synthase (EC 2.5.1.16) compare
PfGW456L13_3980 -1.3 -8.1 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
PfGW456L13_4040 -1.3 -1.9 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
PfGW456L13_3985 -1.3 -8.6 hypothetical protein compare
PfGW456L13_4051 -1.3 -1.3 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
PfGW456L13_1011 -1.3 -2.0 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_3517 -1.3 -4.0 Aldehyde dehydrogenase (EC 1.2.1.3) compare
PfGW456L13_3931 -1.3 -1.0 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (EC 4.1.2.n4) compare
PfGW456L13_4642 -1.3 -1.5 Cold shock protein CspA compare
PfGW456L13_3302 -1.2 -1.1 FIG00954674: hypothetical protein compare
PfGW456L13_2952 -1.2 -2.3 2-ketogluconate utilization repressor PtxS compare
PfGW456L13_1099 -1.2 -1.3 FIG00953563: hypothetical protein compare
PfGW456L13_303 -1.2 -1.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_4512 -1.2 -4.0 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_727 -1.2 -3.8 LysR family transcriptional regulator PA5437 compare
PfGW456L13_3984 -1.2 -9.3 Lipopolysaccharide biosynthesis protein RffA compare
PfGW456L13_3591 -1.2 -1.8 hypothetical protein compare
PfGW456L13_4582 -1.2 -2.9 RND efflux system, outer membrane lipoprotein CmeC compare
PfGW456L13_1705 -1.2 -1.5 FIG00955494: hypothetical protein compare
PfGW456L13_3522 -1.2 -2.8 Cytochrome C550 (Soluble cytochrome C) compare
PfGW456L13_4238 -1.2 -2.6 Cobyric acid synthase (EC 6.3.5.10) compare
PfGW456L13_2933 -1.2 -1.7 LysR family transcriptional regulator STM2281 compare
PfGW456L13_3107 -1.2 -2.2 Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) compare
PfGW456L13_2608 -1.2 -1.3 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
PfGW456L13_5074 -1.1 -1.0 1-phosphofructokinase (EC 2.7.1.56) compare
PfGW456L13_605 -1.1 -1.2 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
PfGW456L13_674 -1.1 -2.5 Chromosome (plasmid) partitioning protein ParB compare
PfGW456L13_953 -1.1 -7.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_4365 -1.1 -3.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
PfGW456L13_742 -1.1 -2.5 Aspartate ammonia-lyase (EC 4.3.1.1) compare
PfGW456L13_4041 -1.1 -1.6 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_2908 -1.1 -0.9 hypothetical protein compare
PfGW456L13_729 -1.1 -5.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_152 -1.1 -3.1 HflK protein compare
PfGW456L13_3641 -1.1 -1.7 hypothetical protein compare
PfGW456L13_327 -1.1 -2.9 hypothetical protein compare
PfGW456L13_758 -1.1 -1.8 Phosphate regulon transcriptional regulatory protein PhoB (SphR) compare
PfGW456L13_282 -1.1 -6.7 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
PfGW456L13_360 -1.1 -2.1 FIG00956267: hypothetical protein compare
PfGW456L13_144 -1.1 -3.3 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_3398 -1.1 -2.2 Transcriptional regulator, TetR family compare
PfGW456L13_3577 -1.0 -1.2 hypothetical protein compare
PfGW456L13_2221 -1.0 -5.7 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_2885 -1.0 -4.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
PfGW456L13_69 -1.0 -0.8 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
PfGW456L13_2006 -1.0 -1.6 hypothetical protein compare
PfGW456L13_3523 -1.0 -4.0 FIG00953323: hypothetical protein compare
PfGW456L13_4231 -1.0 -0.9 hypothetical protein compare
PfGW456L13_848 -1.0 -2.6 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
PfGW456L13_3000 -1.0 -1.3 FIG00961385: hypothetical protein compare
PfGW456L13_3528 -1.0 -3.4 Transcriptional regulator, LuxR family compare
PfGW456L13_1212 -1.0 -7.3 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
PfGW456L13_3694 -1.0 -2.3 Arsenical resistance operon repressor compare
PfGW456L13_1192 -1.0 -2.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_4883 -1.0 -3.0 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
PfGW456L13_973 -1.0 -4.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_236 -1.0 -0.6 Acyl carrier protein (ACP1) compare
PfGW456L13_3052 -1.0 -1.4 Response regulator compare
PfGW456L13_1851 -1.0 -2.1 Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) compare
PfGW456L13_3521 -1.0 -3.2 amino acid ABC transporter, periplasmic substrate-binding protein compare
PfGW456L13_3520 -1.0 -2.4 FIG00956261: hypothetical protein compare
PfGW456L13_728 -1.0 -5.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_2193 -1.0 -4.3 Probable short-chain dehydrogenase compare
PfGW456L13_4668 -1.0 -2.3 RecA protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Malic acid disodium salt monohydrate in Pseudomonas fluorescens GW456-L13

For carbon source L-Malic acid disodium salt monohydrate across organisms