Experiment set2IT056 for Pseudomonas fluorescens GW456-L13

Compare to:

Trisodium citrate dihydrate carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_2310 -6.9 -4.8 FIG137594: Putative iron-regulated membrane protein compare
PfGW456L13_362 -6.8 -6.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_3934 -6.7 -6.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_2842 -6.6 -4.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_2011 -6.6 -4.5 Transcriptional regulatory protein PhoP compare
PfGW456L13_172 -6.5 -4.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_358 -6.5 -2.5 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_973 -6.5 -7.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_149 -6.5 -4.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_5000 -6.4 -6.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_1007 -6.4 -4.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_4781 -6.3 -2.5 Nudix hydrolase family protein PA3470 compare
PfGW456L13_3940 -6.3 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_359 -6.3 -7.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_2306 -6.2 -7.4 FIG014801: Cation ABC transporter, periplasmic cation-binding protein compare
PfGW456L13_1472 -6.1 -4.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_3547 -6.1 -6.0 Cobalt-zinc-cadmium resistance protein CzcD conserved
PfGW456L13_2046 -6.1 -4.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_3947 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_959 -6.1 -10.9 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) conserved
PfGW456L13_1222 -6.1 -4.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_1540 -6.1 -5.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_4618 -6.0 -3.8 Outer membrane lipoprotein compare
PfGW456L13_2010 -6.0 -8.2 outer membrane protein H1 compare
PfGW456L13_990 -6.0 -3.8 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_303 -5.9 -2.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_3948 -5.9 -5.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_2307 -5.8 -6.9 FIG049111: Hypothetical protein in pyoverdin gene cluster compare
PfGW456L13_2176 -5.8 -10.5 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_2084 -5.8 -2.6 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_202 -5.8 -4.0 Probable transcription regulator Mig-14 compare
PfGW456L13_1010 -5.8 -7.9 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_3945 -5.8 -10.4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_2304 -5.7 -5.5 ABC transporter in pyoverdin gene cluster, permease component compare
PfGW456L13_5001 -5.7 -9.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_845 -5.7 -3.9 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_4125 -5.7 -2.8 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_1221 -5.6 -14.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1050 -5.6 -6.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_361 -5.6 -12.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_1739 -5.5 -7.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_951 -5.4 -14.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_1217 -5.4 -21.7 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_302 -5.4 -6.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_2305 -5.4 -5.2 ABC transporter in pyoverdin gene cluster, ATP-binding component compare
PfGW456L13_150 -5.4 -2.0 hypothetical protein compare
PfGW456L13_4524 -5.3 -8.8 Tricarboxylate transport transcriptional regulator TctD conserved
PfGW456L13_201 -5.3 -6.2 Hypothetical protein FIG015671 in large core OS assembly cluster compare
PfGW456L13_5089 -5.3 -1.2 Transcription termination protein NusA compare
PfGW456L13_2384 -5.2 -18.4 TonB-dependent siderophore receptor compare
PfGW456L13_2551 -5.2 -3.5 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_1524 -5.2 -5.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_1539 -5.2 -11.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_913 -5.1 -7.8 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_1020 -5.1 -9.8 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_4026 -5.1 -2.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_958 -5.0 -11.8 Cd(II)/Pb(II)-responsive transcriptional regulator conserved
PfGW456L13_565 -5.0 -3.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_332 -5.0 -2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_4122 -5.0 -10.1 FIG002781: Alpha-L-glutamate ligase family protein compare
PfGW456L13_1545 -5.0 -8.3 Paraquat-inducible protein A compare
PfGW456L13_1147 -4.9 -16.2 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_926 -4.9 -14.1 glutamine synthetase family protein compare
PfGW456L13_1749 -4.9 -3.4 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_2303 -4.8 -10.4 ABC transporter in pyoverdin gene cluster, periplasmic component compare
PfGW456L13_1546 -4.8 -14.6 Paraquat-inducible protein B compare
PfGW456L13_1845 -4.8 -3.3 Cold shock protein CspC compare
PfGW456L13_1580 -4.8 -8.0 FIG140336: TPR domain protein compare
PfGW456L13_4038 -4.8 -2.6 DNA topoisomerase I (EC 5.99.1.2) compare
PfGW456L13_2552 -4.8 -6.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1544 -4.8 -8.5 Paraquat-inducible protein A compare
PfGW456L13_1233 -4.8 -3.3 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1538 -4.7 -16.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_3960 -4.6 -10.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_656 -4.6 -3.2 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_1479 -4.6 -1.0 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
PfGW456L13_2843 -4.6 -10.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_2032 -4.6 -7.0 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_943 -4.6 -8.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_2309 -4.6 -6.0 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
PfGW456L13_1972 -4.5 -2.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_854 -4.5 -2.8 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_4254 -4.5 -9.8 FIG00955360: hypothetical protein compare
PfGW456L13_350 -4.5 -4.3 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
PfGW456L13_2933 -4.5 -3.3 LysR family transcriptional regulator STM2281 compare
PfGW456L13_1615 -4.4 -1.4 Probable transmembrane protein compare
PfGW456L13_4859 -4.4 -3.0 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_4526 -4.4 -11.6 Tricarboxylate transport protein TctC conserved
PfGW456L13_1153 -4.4 -14.2 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
PfGW456L13_2230 -4.4 -8.2 Cys regulon transcriptional activator CysB compare
PfGW456L13_566 -4.4 -9.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_728 -4.3 -12.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_2602 -4.2 -9.7 putative exported protein compare
PfGW456L13_2656 -4.2 -7.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1625 -4.2 -3.1 FIG00958649: hypothetical protein compare
PfGW456L13_2035 -4.1 -13.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_2237 -4.1 -2.9 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2308 -4.1 -6.0 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
PfGW456L13_4121 -4.0 -7.4 FIG139976: hypothetical protein compare
PfGW456L13_4671 -4.0 -10.8 Transcriptional regulator, Cro/CI family compare
PfGW456L13_5008 -4.0 -2.0 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_4012 -4.0 -2.3 VacJ-like lipoprotein precursor compare
PfGW456L13_1354 -4.0 -10.3 DedA protein compare
PfGW456L13_1219 -4.0 -5.0 hypothetical protein compare
PfGW456L13_1006 -3.9 -4.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_275 -3.9 -2.1 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_4014 -3.9 -1.2 Chromosome segregation ATPases compare
PfGW456L13_2385 -3.9 -1.9 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
PfGW456L13_793 -3.9 -3.8 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_59 -3.9 -5.3 Sensor histidine kinase/response regulator compare
PfGW456L13_4108 -3.9 -2.2 CrfX protein compare
PfGW456L13_1838 -3.8 -6.3 Sensory box histidine kinase compare
PfGW456L13_3846 -3.8 -2.3 Predicted secretion system X FIG084745: hypothetical protein compare
PfGW456L13_5086 -3.7 -5.1 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_2538 -3.7 -1.2 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
PfGW456L13_4165 -3.7 -4.9 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_1368 -3.7 -4.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_852 -3.6 -1.1 FIG00954215: hypothetical protein compare
PfGW456L13_668 -3.6 -1.6 Ribonuclease P protein component (EC 3.1.26.5) compare
PfGW456L13_729 -3.6 -10.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_1029 -3.6 -1.1 Triphosphoribosyl-dephospho-CoA synthetase (EC 2.7.8.25) compare
PfGW456L13_1220 -3.5 -5.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_3398 -3.5 -4.2 Transcriptional regulator, TetR family compare
PfGW456L13_1735 -3.5 -4.1 Glycerol uptake facilitator protein compare
PfGW456L13_4955 -3.5 -1.7 FIG00954638: hypothetical protein compare
PfGW456L13_5005 -3.5 -3.4 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_4009 -3.5 -9.7 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_276 -3.4 -1.1 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_2601 -3.4 -12.1 Uncharacterized protein YtfM precursor compare
PfGW456L13_1984 -3.4 -2.6 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_644 -3.4 -9.7 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_2191 -3.4 -12.0 nucleotide sugar epimerase/dehydratase WbpM compare
PfGW456L13_4527 -3.3 -8.7 tricarboxylate transporter component TctB (from data) conserved
PfGW456L13_5150 -3.3 -3.9 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_779 -3.3 -10.8 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_1492 -3.3 -5.0 Probable component of the lipoprotein assembly complex (forms a complex with YaeT, YfgL, and NlpB) compare
PfGW456L13_1863 -3.3 -8.6 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_2556 -3.3 -3.5 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
PfGW456L13_2034 -3.2 -2.5 hypothetical protein compare
PfGW456L13_4854 -3.2 -8.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_427 -3.2 -1.6 Two-component system response regulator OmpR compare
PfGW456L13_4882 -3.1 -4.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_4528 -3.1 -11.1 Tricarboxylate transport membrane protein TctA conserved
PfGW456L13_757 -3.1 -3.2 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_1842 -3.1 -10.3 Outer membrane porin, OprD family compare
PfGW456L13_2436 -3.0 -6.2 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1139 -3.0 -8.4 Malate synthase G (EC 2.3.3.9) compare
PfGW456L13_1440 -3.0 -7.5 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) compare
PfGW456L13_1642 -3.0 -8.4 LppC putative lipoprotein compare
PfGW456L13_4217 -3.0 -1.5 Sodium-dependent transporter compare
PfGW456L13_1973 -2.9 -7.3 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_4207 -2.9 -5.8 Periplasmic protease compare
PfGW456L13_2651 -2.9 -4.0 Cell division protein FtsK compare
PfGW456L13_4999 -2.8 -10.1 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_1824 -2.8 -1.8 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_5082 -2.8 -6.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_203 -2.8 -7.7 Glycosyl transferase in large core OS assembly cluster compare
PfGW456L13_1363 -2.8 -6.0 Rare lipoprotein A precursor compare
PfGW456L13_1009 -2.7 -2.5 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_2182 -2.7 -7.0 regulator of length of O-antigen component of lipopolysaccharide chains compare
PfGW456L13_1148 -2.7 -12.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_605 -2.7 -2.5 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
PfGW456L13_1731 -2.7 -1.7 NADH:flavin oxidoreductases, Old Yellow Enzyme family compare
PfGW456L13_351 -2.7 -3.2 Glutaredoxin 3 (Grx3) compare
PfGW456L13_1151 -2.7 -9.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_4640 -2.7 -2.1 FIG00955308: hypothetical protein compare
PfGW456L13_769 -2.6 -1.1 DNA-binding protein HU-alpha compare
PfGW456L13_4365 -2.6 -3.2 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
PfGW456L13_3982 -2.5 -1.8 hypothetical protein compare
PfGW456L13_2189 -2.5 -6.2 UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid transferase compare
PfGW456L13_3704 -2.4 -3.3 Transcriptional regulator RpiR in protein degradation cluster compare
PfGW456L13_727 -2.4 -4.8 LysR family transcriptional regulator PA5437 compare
PfGW456L13_4041 -2.4 -2.0 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_2256 -2.4 -11.9 sensor histidine kinase/response regulator compare
PfGW456L13_2649 -2.3 -2.9 Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) compare
PfGW456L13_2450 -2.3 -3.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_4523 -2.3 -7.5 Tricarboxylate transport sensor protein TctE conserved
PfGW456L13_1044 -2.3 -9.4 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_63 -2.2 -2.8 hypothetical protein compare
PfGW456L13_4346 -2.2 -3.1 Hpt domain protein compare
PfGW456L13_756 -2.2 -5.1 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_5067 -2.2 -8.9 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_1017 -2.2 -1.7 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
PfGW456L13_2186 -2.2 -4.0 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) compare
PfGW456L13_635 -2.2 -12.1 Uncharacterized transporter, similarity to citrate transporter conserved
PfGW456L13_949 -2.1 -9.0 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_4040 -2.1 -1.9 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
PfGW456L13_3179 -2.1 -3.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_367 -2.1 -3.3 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
PfGW456L13_2554 -2.1 -8.2 ATP-dependent protease La (EC 3.4.21.53) Type I compare
PfGW456L13_3980 -2.1 -10.0 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
PfGW456L13_621 -2.1 -2.5 hypothetical protein compare
PfGW456L13_4512 -2.1 -4.4 Exported zinc metalloprotease YfgC precursor compare
PfGW456L13_1853 -2.1 -1.9 Holliday junction DNA helicase RuvB compare
PfGW456L13_4088 -2.1 -2.0 Transcriptional regulator, GntR family compare
PfGW456L13_844 -2.0 -1.6 Diaminopimelate epimerase (EC 5.1.1.7) compare
PfGW456L13_3591 -2.0 -1.2 hypothetical protein compare
PfGW456L13_355 -2.0 -3.8 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_2597 -2.0 -4.6 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
PfGW456L13_2250 -2.0 -8.6 Probable protease htpX homolog (EC 3.4.24.-) compare


Specific Phenotypes

For 30 genes in this experiment

For carbon source Trisodium citrate dihydrate in Pseudomonas fluorescens GW456-L13

For carbon source Trisodium citrate dihydrate across organisms