Experiment set2IT054 for Pseudomonas fluorescens GW456-L13

Compare to:

a-Ketoglutaric acid disodium salt hydrate carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_362 -6.7 -4.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_973 -6.3 -6.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_1217 -6.2 -10.3 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_172 -6.1 -4.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_358 -6.1 -2.0 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_1010 -6.0 -4.2 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_361 -6.0 -10.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_2176 -6.0 -5.8 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_1007 -5.9 -4.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_2842 -5.9 -3.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_302 -5.8 -3.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_3940 -5.8 -5.6 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1472 -5.7 -3.8 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_1222 -5.6 -3.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_1540 -5.6 -5.5 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_1368 -5.6 -3.4 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_303 -5.5 -2.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_2046 -5.5 -3.8 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_644 -5.5 -7.5 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_3948 -5.5 -3.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_3934 -5.5 -12.2 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_1221 -5.5 -15.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1539 -5.4 -5.3 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_951 -5.3 -11.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_845 -5.2 -3.6 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_1050 -5.2 -5.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_5001 -5.2 -8.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_3945 -5.2 -9.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_3947 -5.1 -4.5 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1739 -5.1 -3.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_5000 -5.1 -14.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_1151 -5.1 -9.8 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_4125 -5.0 -2.2 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_1524 -4.9 -3.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_150 -4.9 -1.6 hypothetical protein compare
PfGW456L13_1863 -4.9 -8.7 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_296 -4.8 -2.3 Polyhydroxyalkanoate granule-associated protein PhaF compare
PfGW456L13_1148 -4.8 -15.4 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_566 -4.8 -4.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_66 -4.6 -1.6 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
PfGW456L13_2843 -4.6 -9.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_427 -4.6 -1.6 Two-component system response regulator OmpR compare
PfGW456L13_565 -4.6 -3.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_1147 -4.6 -14.9 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_793 -4.6 -2.5 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_1538 -4.5 -10.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_359 -4.5 -7.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_779 -4.4 -11.6 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_1219 -4.4 -3.9 hypothetical protein compare
PfGW456L13_1806 -4.4 -8.4 Nitrogen regulation protein NR(I) conserved
PfGW456L13_943 -4.4 -8.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_1044 -4.4 -11.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_913 -4.3 -8.6 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_1233 -4.3 -2.9 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1603 -4.3 -1.9 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_125 -4.2 -0.8 hypothetical protein compare
PfGW456L13_2032 -4.2 -5.7 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_1150 -4.2 -13.0 Biotin synthesis protein BioC compare
PfGW456L13_420 -4.2 -1.6 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_2603 -4.1 -1.1 Transcriptional regulator, MarR family compare
PfGW456L13_854 -4.0 -2.2 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_283 -4.0 -12.2 NADP-dependent malic enzyme (EC 1.1.1.40) compare
PfGW456L13_4088 -4.0 -2.5 Transcriptional regulator, GntR family compare
PfGW456L13_3960 -3.9 -11.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_2230 -3.9 -8.3 Cys regulon transcriptional activator CysB compare
PfGW456L13_1972 -3.9 -1.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_4859 -3.9 -2.7 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_5082 -3.8 -5.8 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_1749 -3.8 -5.2 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_1006 -3.8 -4.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1996 -3.7 -2.1 Flagellar biosynthesis protein FlgN compare
PfGW456L13_2656 -3.7 -6.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_149 -3.7 -4.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_1973 -3.7 -6.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_2595 -3.7 -3.2 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
PfGW456L13_4854 -3.6 -10.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_4236 -3.6 -1.7 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
PfGW456L13_1220 -3.5 -6.3 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_2597 -3.5 -5.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
PfGW456L13_275 -3.5 -1.7 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_5067 -3.5 -12.0 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_1615 -3.5 -1.3 Probable transmembrane protein compare
PfGW456L13_4999 -3.4 -11.6 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_4165 -3.4 -3.2 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_1363 -3.4 -5.6 Rare lipoprotein A precursor compare
PfGW456L13_276 -3.4 -0.9 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_2920 -3.3 -1.3 FIG00962345: hypothetical protein compare
PfGW456L13_4517 -3.3 -16.2 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_4960 -3.3 -3.0 Maleylacetoacetate isomerase (EC 5.2.1.2) @ Glutathione S-transferase, zeta (EC 2.5.1.18) compare
PfGW456L13_5011 -3.3 -2.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
PfGW456L13_2623 -3.2 -2.0 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_1735 -3.2 -2.2 Glycerol uptake facilitator protein compare
PfGW456L13_4007 -3.2 -3.1 Phosphomannomutase (EC 5.4.2.8) compare
PfGW456L13_843 -3.2 -3.6 Protein of unknown function DUF484 compare
PfGW456L13_1181 -3.1 -1.9 hypothetical protein compare
PfGW456L13_2818 -3.1 -1.6 FIG028220: hypothetical protein co-occurring with HEAT repeat protein compare
PfGW456L13_1655 -3.1 -2.2 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_1611 -3.0 -2.0 FIG00954698: hypothetical protein compare
PfGW456L13_2239 -3.0 -3.9 hypothetical protein compare
PfGW456L13_75 -3.0 -2.5 Putative multicopper oxidases compare
PfGW456L13_5008 -2.9 -1.7 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_5006 -2.9 -1.5 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_1769 -2.9 -2.6 SAM-dependent methyltransferases compare
PfGW456L13_4121 -2.9 -9.3 FIG139976: hypothetical protein compare
PfGW456L13_2271 -2.9 -1.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_4253 -2.9 -4.0 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_3179 -2.9 -3.8 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_5039 -2.9 -3.2 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
PfGW456L13_1546 -2.8 -13.5 Paraquat-inducible protein B compare
PfGW456L13_2763 -2.8 -3.4 putative tellurium resistance protein compare
PfGW456L13_5089 -2.8 -1.1 Transcription termination protein NusA compare
PfGW456L13_1805 -2.8 -13.6 Dicarboxylate MFS transporter conserved
PfGW456L13_498 -2.8 -0.9 hypothetical protein compare
PfGW456L13_1807 -2.7 -10.5 C4-dicarboxylate transport sensor protein conserved
PfGW456L13_2385 -2.7 -1.6 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
PfGW456L13_952 -2.7 -6.1 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_4842 -2.7 -1.7 Translation elongation factor LepA compare
PfGW456L13_756 -2.7 -5.4 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_757 -2.7 -2.4 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_1544 -2.6 -7.5 Paraquat-inducible protein A compare
PfGW456L13_1838 -2.6 -5.9 Sensory box histidine kinase compare
PfGW456L13_1580 -2.6 -7.9 FIG140336: TPR domain protein compare
PfGW456L13_4033 -2.5 -2.0 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
PfGW456L13_5005 -2.5 -4.9 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_2237 -2.5 -2.1 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2321 -2.5 -2.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_1628 -2.4 -5.8 ATPase, AFG1 family compare
PfGW456L13_1284 -2.4 -2.0 Putative transport protein compare
PfGW456L13_4026 -2.4 -1.6 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_1975 -2.4 -3.4 Succinylarginine dihydrolase (EC 3.5.3.23) compare
PfGW456L13_1545 -2.4 -8.1 Paraquat-inducible protein A compare
PfGW456L13_4477 -2.4 -3.4 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
PfGW456L13_2103 -2.3 -3.8 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_3445 -2.3 -2.3 hypothetical protein compare
PfGW456L13_2297 -2.3 -3.5 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
PfGW456L13_5059 -2.3 -1.3 hypothetical protein compare
PfGW456L13_4419 -2.3 -1.5 Permeases of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_4051 -2.2 -1.1 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
PfGW456L13_2552 -2.2 -5.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1845 -2.2 -2.9 Cold shock protein CspC compare
PfGW456L13_2551 -2.2 -2.5 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_4207 -2.2 -4.8 Periplasmic protease compare
PfGW456L13_4218 -2.2 -1.3 Quaternary ammonium compound-resistance protein SugE compare
PfGW456L13_3409 -2.2 -2.0 Transcriptional regulator, IclR family compare
PfGW456L13_360 -2.2 -2.2 FIG00956267: hypothetical protein compare
PfGW456L13_4259 -2.1 -0.8 FIG00953296: hypothetical protein compare
PfGW456L13_1192 -2.1 -2.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_3017 -2.1 -1.6 Cold-shock DNA-binding domain compare
PfGW456L13_4122 -2.1 -6.2 FIG002781: Alpha-L-glutamate ligase family protein compare
PfGW456L13_582 -2.1 -1.3 probable exported protein YPO0432 compare
PfGW456L13_3537 -2.1 -2.7 Transcriptional regulator, ArsR family compare
PfGW456L13_355 -2.1 -4.6 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_2582 -2.0 -2.9 RNA polymerase sigma-54 factor RpoN compare
PfGW456L13_4254 -2.0 -6.1 FIG00955360: hypothetical protein compare
PfGW456L13_1356 -1.9 -3.9 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
PfGW456L13_4929 -1.9 -2.4 hypothetical protein compare
PfGW456L13_1824 -1.9 -1.3 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_4883 -1.9 -3.8 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
PfGW456L13_3558 -1.9 -3.8 Glutathione-regulated potassium-efflux system protein KefB compare
PfGW456L13_3810 -1.9 -1.2 hypothetical protein compare
PfGW456L13_3968 -1.9 -0.9 hypothetical protein compare
PfGW456L13_742 -1.9 -2.6 Aspartate ammonia-lyase (EC 4.3.1.1) compare
PfGW456L13_656 -1.9 -2.6 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_1604 -1.9 -5.9 hypothetical protein compare
PfGW456L13_4038 -1.9 -2.4 DNA topoisomerase I (EC 5.99.1.2) compare
PfGW456L13_2856 -1.8 -1.7 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
PfGW456L13_144 -1.8 -4.9 3'-to-5' exoribonuclease RNase R compare
PfGW456L13_3372 -1.8 -2.0 hypothetical protein compare
PfGW456L13_2800 -1.8 -1.6 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
PfGW456L13_2631 -1.8 -2.5 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_1916 -1.8 -1.3 hypothetical protein compare
PfGW456L13_1528 -1.8 -1.7 C4-type zinc finger protein, DksA/TraR family compare
PfGW456L13_527 -1.8 -2.4 Transcriptional regulator compare
PfGW456L13_753 -1.8 -8.0 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
PfGW456L13_568 -1.8 -2.4 FIG00953718: hypothetical protein compare
PfGW456L13_1852 -1.8 -3.6 Holliday junction DNA helicase RuvA compare
PfGW456L13_4582 -1.7 -4.3 RND efflux system, outer membrane lipoprotein CmeC compare
PfGW456L13_4829 -1.7 -1.5 Predicted transcriptional regulator of N-Acetylglucosamine utilization, GntR family compare
PfGW456L13_4618 -1.7 -1.7 Outer membrane lipoprotein compare
PfGW456L13_2981 -1.7 -0.9 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_2851 -1.7 -2.7 Cobalt-precorrin-3b C17-methyltransferase compare
PfGW456L13_3398 -1.7 -2.7 Transcriptional regulator, TetR family compare
PfGW456L13_152 -1.6 -3.8 HflK protein compare
PfGW456L13_4719 -1.6 -2.2 HesA/MoeB/ThiF family protein related to EC-YgdL compare
PfGW456L13_2268 -1.6 -1.6 Thiol-disulfide isomerase and thioredoxins compare
PfGW456L13_3756 -1.6 -3.1 Succinyl-CoA synthetase, alpha subunit compare
PfGW456L13_2821 -1.6 -2.0 DNA polymerase-like protein PA0670 compare
PfGW456L13_2484 -1.6 -3.1 Transcriptional regulators, LysR family compare
PfGW456L13_259 -1.6 -1.0 General secretion pathway protein K compare
PfGW456L13_4944 -1.6 -0.7 FIG00963370: hypothetical protein compare
PfGW456L13_621 -1.6 -1.4 hypothetical protein compare
PfGW456L13_5060 -1.6 -3.6 Peptide chain release factor 3 compare
PfGW456L13_2478 -1.6 -2.3 FIG00956937: hypothetical protein compare
PfGW456L13_4907 -1.6 -1.2 hypothetical protein compare
PfGW456L13_2925 -1.5 -1.4 Cointegrate resolution protein T compare
PfGW456L13_1976 -1.5 -1.4 Putative GTPases (G3E family) compare
PfGW456L13_3835 -1.5 -1.8 FIG00957304: hypothetical protein compare
PfGW456L13_2644 -1.5 -1.7 Cold shock protein CspD compare
PfGW456L13_271 -1.5 -7.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_1448 -1.5 -2.7 Transcriptional regulator, GntR family compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Pseudomonas fluorescens GW456-L13

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms