Experiment set2IT052 for Escherichia coli BW25113

Compare to:

LB with Fusidic acid sodium salt 0.1 mg/ml

200 most important genes:

  gene name fitness t score description  
b0463 acrA -4.7 -5.6 multidrug efflux system (NCBI) compare
b0462 acrB -4.3 -10.3 multidrug efflux system protein (NCBI) compare
b3035 tolC -4.0 -4.8 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3021 ygiT -3.7 -4.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b3199 yrbK -3.6 -3.5 hypothetical protein (NCBI) compare
b0082 mraW -3.4 -3.3 S-adenosyl-methyltransferase (NCBI) compare
b0222 lpcA -3.4 -2.3 phosphoheptose isomerase (NCBI) compare
b3631 rfaG -3.3 -13.4 glucosyltransferase I (NCBI) compare
b3052 rfaE -3.2 -3.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b4203 rplI -3.2 -2.2 50S ribosomal protein L9 (NCBI) compare
b2188 yejM -2.9 -7.1 predicted hydrolase, inner membrane (NCBI) compare
b3620 rfaF -2.9 -2.8 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3621 rfaC -2.7 -1.8 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3842 rfaH -2.7 -3.6 transcriptional activator RfaH (NCBI) compare
b3630 rfaP -2.6 -10.3 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3636 rpmG -2.5 -2.4 50S ribosomal protein L33 (NCBI) compare
b3619 rfaD -2.5 -1.7 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2512 yfgL -2.4 -4.4 protein assembly complex, lipoprotein component (NCBI) compare
b1164 ycgZ -2.3 -3.3 hypothetical protein (NCBI) compare
b2699 recA -2.1 -1.4 recombinase A (NCBI) compare
b0739 tolA -2.1 -3.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0200 gmhB -2.0 -1.4 hypothetical protein (NCBI) compare
b2494 yfgC -2.0 -7.0 predicted peptidase (NCBI) compare
b0737 tolQ -2.0 -3.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0053 surA -2.0 -3.7 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b4172 hfq -1.9 -2.2 RNA-binding protein Hfq (NCBI) compare
b3726 pstA -1.9 -6.0 phosphate transporter subunit (NCBI) compare
b3725 pstB -1.8 -2.1 phosphate transporter subunit (NCBI) compare
b4418 sraB -1.8 -1.7 unknown RNA (NCBI) compare
b2894 xerD -1.8 -1.7 site-specific tyrosine recombinase XerD (NCBI) compare
b2576 srmB -1.8 -3.2 ATP-dependent RNA helicase (NCBI) compare
b2567 rnc -1.8 -2.0 ribonuclease III (NCBI) compare
b1085 b1085 -1.8 -1.9 orf, hypothetical protein (VIMSS) compare
b2259 pmrD -1.7 -1.9 polymyxin resistance protein B (VIMSS) compare
b3463 ftsE -1.6 -4.1 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3082 ygjM -1.6 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b3483 yhhH -1.6 -2.3 orf, hypothetical protein (VIMSS) compare
b3462 ftsX -1.6 -5.2 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0014 dnaK -1.6 -1.7 molecular chaperone DnaK (NCBI) compare
b1252 tonB -1.6 -2.6 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b3613 yibP -1.6 -5.1 putative membrane protein (VIMSS) compare
b3728 pstS -1.6 -3.8 phosphate transporter subunit (NCBI) compare
b4062 soxS -1.5 -3.9 DNA-binding transcriptional dual regulator (NCBI) compare
b0741 pal -1.5 -3.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2820 recB -1.5 -2.3 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1712 ihfA -1.5 -2.7 integration host factor subunit alpha (NCBI) compare
b0738 tolR -1.4 -2.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1860 ruvB -1.4 -1.7 Holliday junction DNA helicase B (NCBI) compare
b1818 manY -1.4 -2.2 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1358 ydaT -1.3 -1.8 Rac prophage; predicted protein (NCBI) compare
b3387 dam -1.3 -8.2 DNA adenine methylase (NCBI) compare
b2330 yfcB -1.3 -2.2 putative adenine-specific methylase (VIMSS) compare
b2363 yfdT -1.3 -2.5 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1863 ruvC -1.3 -2.8 Holliday junction resolvase (NCBI) compare
b3632 rfaQ -1.3 -10.5 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0890 ftsK -1.3 -5.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0436 tig -1.2 -5.7 trigger factor (NCBI) compare
b1545 pinQ -1.2 -1.3 Qin prophage; predicted site-specific recombinase (NCBI) compare
b0623 cspE -1.2 -1.5 cold shock protein E (NCBI) compare
b0740 tolB -1.2 -3.3 translocation protein TolB precursor (NCBI) compare
b0912 ihfB -1.2 -2.7 integration host factor subunit beta (NCBI) compare
b3979 thrT -1.2 -1.0 tRNA-Thr (NCBI) compare
b3741 gidA -1.2 -5.5 glucose-inhibited division protein A (NCBI) compare
b1063 yceB -1.2 -2.2 predicted lipoprotein (NCBI) compare
b1861 ruvA -1.2 -2.0 Holliday junction DNA helicase motor protein (NCBI) compare
b1942 fliJ -1.2 -1.2 flagellar biosynthesis chaperone (NCBI) compare
b3247 cafA -1.2 -6.6 bundles of cytoplasmic filaments (VIMSS) compare
b1576 ydfD -1.2 -2.1 Qin prophage; predicted protein (NCBI) compare
b0500 ybbD -1.1 -2.1 hypothetical protein (RefSeq) compare
b0051 ksgA -1.1 -4.3 dimethyladenosine transferase (NCBI) compare
b0605 ahpC -1.1 -3.6 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1426 ydcH -1.1 -1.2 orf, hypothetical protein (VIMSS) compare
b4402 yjjY -1.1 -1.2 hypothetical protein (NCBI) compare
b4577 sgrS -1.1 -1.5 small antisense RNA (NCBI) compare
b0471 ybaB -1.1 -2.6 hypothetical protein (NCBI) compare
b2110 yehC -1.1 -2.9 predicted periplasmic pilin chaperone (NCBI) compare
b0145 dksA -1.1 -2.6 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1853 yebK -1.1 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b4458 oxyS -1.1 -1.0 global regulatory RNA (NCBI) compare
b3198 kdsC -1.1 -2.0 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b1677 lpp -1.1 -2.1 murein lipoprotein (NCBI) compare
b1989 asnV -1.1 -1.9 tRNA-Asn (NCBI) compare
b2055 wcaE -1.1 -2.3 predicted glycosyl transferase (NCBI) compare
b3029 ygiN -1.1 -2.1 quinol monooxygenase (NCBI) compare
b2620 smpB -1.1 -1.4 SsrA-binding protein (NCBI) compare
b3609 secB -1.0 -3.3 export protein SecB (NCBI) compare
b1257 yciE -1.0 -1.9 hypothetical protein (NCBI) compare
b2937 speB -1.0 -4.6 agmatinase (NCBI) compare
b4042 dgkA -1.0 -2.4 diacylglycerol kinase (NCBI) compare
b0580 ybdJ -1.0 -1.6 predicted inner membrane protein (NCBI) compare
b3163 nlpI -1.0 -3.2 hypothetical protein (NCBI) compare
b3005 exbD -1.0 -3.3 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b0683 fur -1.0 -1.3 ferric uptake regulator (NCBI) compare
b2617 smpA -1.0 -1.9 small membrane protein A (VIMSS) compare
b3237 argR -1.0 -3.1 arginine repressor (NCBI) compare
b4414 tff -1.0 -2.0 unknown RNA (NCBI) compare
b1984 asnW -1.0 -1.0 tRNA-Asn (NCBI) compare
b3183 obgE -1.0 -1.3 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1842 holE -1.0 -1.1 DNA polymerase III, theta subunit (NCBI) compare
b3839 tatC -1.0 -5.4 TatABCE protein translocation system subunit (NCBI) compare
b1271 yciK -1.0 -2.0 short chain dehydrogenase (NCBI) compare
b3652 recG -0.9 -5.6 ATP-dependent DNA helicase (NCBI) compare
b2642 yfjW -0.9 -2.0 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1306 pspC -0.9 -2.2 DNA-binding transcriptional activator (NCBI) compare
b2853 ygeI -0.9 -1.7 hypothetical protein (NCBI) compare
b2209 eco -0.9 -1.9 ecotin precursor (NCBI) compare
b3238 yhcN -0.9 -1.4 orf, hypothetical protein (VIMSS) compare
b2064 asmA -0.9 -1.8 predicted assembly protein (NCBI) compare
b4685 yrbN -0.9 -1.8 expressed protein (RefSeq) compare
b4655 ythA -0.9 -1.1 expressed protein (RefSeq) compare
b1730 ydjO -0.9 -2.2 predicted protein (RefSeq) compare
b1236 galU -0.9 -3.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3858 yihD -0.9 -0.8 hypothetical protein (NCBI) compare
b1499 ydeO -0.9 -1.6 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1644 b1644 -0.9 -2.1 putative membrane protein (VIMSS) compare
b2569 lepA -0.9 -2.7 GTP-binding protein LepA (NCBI) compare
b1074 flgC -0.9 -1.3 flagellar basal-body rod protein C (NCBI) compare
b4128 yjdK -0.9 -3.2 hypothetical protein (NCBI) compare
b4603 rseX -0.9 -0.8 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1361 ydaW -0.9 -0.9 orf, hypothetical protein (VIMSS) compare
b0881 clpS -0.9 -1.4 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b1607 ydgC -0.8 -1.3 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b3933 ftsN -0.8 -4.9 essential cell division protein (NCBI) compare
b2910 zapA -0.8 -2.3 protein that localizes to the cytokinetic ring (NCBI) compare
b1438 ydcQ -0.8 -1.8 predicted DNA-binding transcriptional regulator (RefSeq) compare
b0767 ybhE -0.8 -2.2 6-phosphogluconolactonase (NCBI) compare
b1724 ydiZ -0.8 -1.3 hypothetical protein (NCBI) compare
b3146 yraL -0.8 -3.9 predicted methyltransferase (NCBI) compare
b1086 rluC -0.8 -3.0 23S rRNA pseudouridylate synthase (NCBI) compare
b0547 ybcN -0.8 -1.5 DLP12 prophage; predicted protein (NCBI) compare
b0232 yafN -0.8 -0.8 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1795 yeaQ -0.8 -1.6 conserved inner membrane protein (NCBI) compare
b0279 yagM -0.8 -3.3 CP4-6 prophage; predicted protein (NCBI) compare
b2822 recC -0.8 -2.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4590 ybfK -0.8 -3.1 hypothetical protein (RefSeq) compare
b1615 uidC -0.8 -3.1 membrane-associated protein (VIMSS) compare
b1008 ycdI -0.8 -1.7 hypothetical protein (NCBI) compare
b3242 yhcR -0.8 -2.8 orf, hypothetical protein (VIMSS) compare
b1130 phoP -0.8 -3.2 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2510 b2510 -0.8 -2.4 orf, hypothetical protein (VIMSS) compare
b3863 polA -0.8 -0.8 DNA polymerase I (NCBI) compare
b0957 ompA -0.8 -2.2 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3781 trxA -0.8 -2.1 thioredoxin 1 (VIMSS) compare
b2518 ndk -0.8 -1.3 nucleoside diphosphate kinase (NCBI) compare
b2652 ileY -0.8 -3.0 tRNA-Ile (NCBI) compare
b3811 xerC -0.8 -1.5 site-specific tyrosine recombinase XerC (NCBI) compare
b0953 rmf -0.8 -1.5 ribosome modulation factor (NCBI) compare
b1289 ycjD -0.7 -1.8 hypothetical protein (NCBI) compare
b0782 moaB -0.7 -1.3 molybdopterin biosynthesis protein B (NCBI) compare
b1409 ynbB -0.7 -3.2 predicted CDP-diglyceride synthase (NCBI) compare
b1936 intG -0.7 -1.5 predicted defective phage integrase (pseudogene) (RefSeq) compare
b4598 yncL -0.7 -1.2 hypothetical protein (RefSeq) compare
b1067 yceH -0.7 -2.0 hypothetical protein (NCBI) compare
b0142 folK -0.7 -0.8 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1658 purR -0.7 -2.8 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b1247 oppF -0.7 -2.2 oligopeptide transporter subunit (NCBI) compare
b2071 yegJ -0.7 -1.4 hypothetical protein (NCBI) compare
b2579 yfiD -0.7 -1.3 pyruvate formate lyase subunit (NCBI) compare
b2187 yejL -0.7 -1.0 hypothetical protein (NCBI) compare
b4406 yaeP -0.7 -0.9 hypothetical protein (NCBI) compare
b4443 gcvB -0.7 -0.8 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b4178 yjeB -0.7 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0804 ybiX -0.7 -1.7 putative enzyme (VIMSS) compare
b4202 rpsR -0.7 -1.2 30S ribosomal protein S18 (NCBI) compare
b4179 vacB -0.7 -3.5 putative enzyme (VIMSS) compare
b3727 pstC -0.7 -3.2 phosphate transporter subunit (NCBI) compare
b1573 ydfC -0.7 -1.1 Qin prophage; predicted protein (RefSeq) compare
b1413 hrpA -0.7 -3.6 ATP-dependent helicase (RefSeq) compare
b4631 ykgQ -0.7 -0.9 no description compare
b3961 oxyR -0.7 -4.4 DNA-binding transcriptional dual regulator (NCBI) compare
b1523 yneG -0.7 -1.1 hypothetical protein (NCBI) compare
b0705 ybfL -0.7 -1.9 putative receptor protein (VIMSS) compare
b1217 chaB -0.7 -1.0 cation transport regulator (NCBI) compare
b3203 yhbH -0.7 -1.9 predicted ribosome-associated, sigma 54 modulation protein (NCBI) compare
b3465 yhhF -0.7 -3.0 predicted methyltransferase (NCBI) compare
b2706 gutM -0.7 -1.4 DNA-binding transcriptional activator of glucitol operon (NCBI) compare
b1480 sra -0.7 -1.3 30S ribosomal subunit protein S22 (NCBI) compare
b0955 ycbZ -0.7 -3.1 predicted peptidase (NCBI) compare
b3027 ygiZ -0.7 -1.6 conserved inner membrane protein (NCBI) compare
b2847 yqeI -0.7 -3.4 predicted transcriptional regulator (NCBI) compare
b1551 b1551 -0.7 -1.1 orf, hypothetical protein (VIMSS) compare
b4373 rimI -0.7 -1.3 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b4017 arpA -0.7 -3.9 regulator of acetyl CoA synthetase (NCBI) compare
b4189 yjfO -0.7 -3.0 orf, hypothetical protein (VIMSS) compare
b4648 ysaC -0.7 -1.5 no description compare
b2634 yfjR -0.6 -1.6 CP4-57 prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b2735 ygbI -0.6 -2.2 predicted DNA-binding transcriptional regulator (RefSeq) compare
b1731 cedA -0.6 -1.4 cell division modulator (RefSeq) compare
b2625 yfjI -0.6 -2.8 CP4-57 prophage; predicted protein (NCBI) compare
b4046 yjbK -0.6 -2.9 putative regulator (VIMSS) compare
b3963 fabR -0.6 -3.9 DNA-binding transcriptional repressor (RefSeq) compare
b4551 yheV -0.6 -0.8 hypothetical protein (NCBI) compare
b1830 prc -0.6 -2.4 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3243 aaeR -0.6 -2.0 predicted DNA-binding transcriptional regulator, efflux system (NCBI) compare
b2824 ygdB -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b1259 yciG -0.6 -1.0 orf, hypothetical protein (VIMSS) compare
b4155 yjeA -0.6 -0.7 putative lysyl-tRNA synthetase (VIMSS) compare
b1558 cspF -0.6 -1.3 Qin prophage; cold shock protein (NCBI) compare
b2513 yfgM -0.6 -2.6 hypothetical protein (NCBI) compare
b0746 valZ -0.6 -1.1 tRNA-Val (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Fusidic acid sodium salt in Escherichia coli BW25113

For stress Fusidic acid sodium salt across organisms