Experiment set2IT050 for Pseudomonas fluorescens GW456-L13

Compare to:

D-Fructose carbon source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_362 -6.9 -4.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_1010 -6.3 -4.3 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_149 -6.3 -4.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_3934 -6.2 -7.4 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_361 -6.2 -10.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_172 -6.0 -5.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_302 -6.0 -4.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_644 -6.0 -5.9 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_3940 -5.9 -7.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_5000 -5.9 -11.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_1222 -5.9 -4.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_1007 -5.8 -6.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1217 -5.8 -19.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_1368 -5.8 -4.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_3947 -5.7 -4.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_303 -5.7 -2.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_1540 -5.7 -7.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_2842 -5.7 -5.3 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_2046 -5.7 -5.5 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_1221 -5.6 -17.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_1539 -5.6 -6.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_3948 -5.5 -5.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_3945 -5.4 -9.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_913 -5.4 -3.8 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_845 -5.4 -3.7 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_1739 -5.3 -6.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_1050 -5.2 -7.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_1472 -5.2 -6.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_150 -5.1 -1.9 hypothetical protein compare
PfGW456L13_951 -5.0 -14.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_2843 -5.0 -11.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_358 -4.9 -2.6 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_2230 -4.9 -8.2 Cys regulon transcriptional activator CysB compare
PfGW456L13_1524 -4.9 -5.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_359 -4.9 -9.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_1538 -4.8 -10.3 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_728 -4.8 -15.8 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_565 -4.8 -3.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_2032 -4.6 -6.3 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_1233 -4.6 -3.1 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_727 -4.5 -10.9 LysR family transcriptional regulator PA5437 compare
PfGW456L13_5001 -4.5 -10.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_1749 -4.5 -3.1 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_953 -4.5 -15.9 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_1147 -4.4 -15.1 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_4038 -4.4 -2.3 DNA topoisomerase I (EC 5.99.1.2) compare
PfGW456L13_2176 -4.3 -8.9 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_4009 -4.3 -16.3 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_1615 -4.3 -1.3 Probable transmembrane protein compare
PfGW456L13_1006 -4.3 -6.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1150 -4.3 -16.5 Biotin synthesis protein BioC compare
PfGW456L13_943 -4.2 -9.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_4859 -4.2 -2.9 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_4125 -4.1 -3.1 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_973 -4.0 -14.0 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_3960 -3.9 -10.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_50 -3.9 -10.7 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_2656 -3.9 -7.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_757 -3.8 -2.7 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_854 -3.8 -3.1 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_5008 -3.8 -1.8 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_656 -3.7 -4.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_275 -3.7 -2.0 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_1044 -3.7 -11.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
PfGW456L13_157 -3.7 -3.3 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
PfGW456L13_1219 -3.6 -4.9 hypothetical protein compare
PfGW456L13_1151 -3.6 -10.9 Dethiobiotin synthetase (EC 6.3.3.3) compare
PfGW456L13_1148 -3.6 -13.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
PfGW456L13_1845 -3.6 -4.6 Cold shock protein CspC compare
PfGW456L13_5082 -3.6 -7.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
PfGW456L13_2552 -3.5 -8.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_4165 -3.5 -4.2 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_355 -3.5 -6.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
PfGW456L13_4487 -3.5 -2.0 FIG00954793: hypothetical protein compare
PfGW456L13_1889 -3.4 -3.3 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_1863 -3.4 -10.4 Quinolinate synthetase (EC 2.5.1.72) compare
PfGW456L13_4854 -3.4 -9.0 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_2623 -3.4 -2.2 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_1603 -3.4 -2.6 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_276 -3.3 -1.0 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_4088 -3.3 -2.5 Transcriptional regulator, GntR family compare
PfGW456L13_729 -3.3 -10.3 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_3398 -3.3 -4.5 Transcriptional regulator, TetR family compare
PfGW456L13_5006 -3.3 -1.9 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_5074 -3.2 -1.2 1-phosphofructokinase (EC 2.7.1.56) compare
PfGW456L13_4012 -3.2 -2.4 VacJ-like lipoprotein precursor compare
PfGW456L13_566 -3.2 -6.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_2633 -3.1 -15.3 Isocitrate lyase (EC 4.1.3.1) compare
PfGW456L13_1220 -3.1 -5.0 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_1838 -3.1 -5.8 Sensory box histidine kinase compare
PfGW456L13_1735 -3.0 -4.1 Glycerol uptake facilitator protein compare
PfGW456L13_420 -3.0 -2.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
PfGW456L13_5073 -3.0 -14.7 PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) conserved
PfGW456L13_3179 -3.0 -4.3 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_1997 -2.9 -5.7 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_5067 -2.9 -11.0 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_1901 -2.9 -9.7 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_4511 -2.9 -1.7 Rhodanese-like domain protein compare
PfGW456L13_952 -2.9 -4.7 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_874 -2.8 -17.0 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_4207 -2.7 -8.1 Periplasmic protease compare
PfGW456L13_352 -2.7 -5.2 FIG136845: Rhodanese-related sulfurtransferase compare
PfGW456L13_2933 -2.7 -3.5 LysR family transcriptional regulator STM2281 compare
PfGW456L13_75 -2.7 -2.5 Putative multicopper oxidases compare
PfGW456L13_1690 -2.6 -2.4 Molybdenum cofactor biosynthesis protein MoaD compare
PfGW456L13_5075 -2.6 -7.6 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) conserved
PfGW456L13_3795 -2.6 -9.6 sensor histidine kinase compare
PfGW456L13_1972 -2.6 -2.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_4253 -2.6 -4.4 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_1528 -2.6 -2.3 C4-type zinc finger protein, DksA/TraR family compare
PfGW456L13_4004 -2.6 -17.3 YjbH outer membrane lipoprotein compare
PfGW456L13_4239 -2.5 -1.0 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
PfGW456L13_5005 -2.5 -5.6 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_4671 -2.4 -9.7 Transcriptional regulator, Cro/CI family compare
PfGW456L13_1574 -2.3 -3.7 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_1386 -2.3 -18.6 Sensor histidine kinase compare
PfGW456L13_2330 -2.3 -2.6 Demethylmenaquinone methyltransferase compare
PfGW456L13_2029 -2.3 -13.0 BarA sensory histidine kinase (= VarS = GacS) compare
PfGW456L13_73 -2.3 -1.5 FIG00955840: hypothetical protein compare
PfGW456L13_2763 -2.3 -4.1 putative tellurium resistance protein compare
PfGW456L13_4254 -2.3 -5.5 FIG00955360: hypothetical protein compare
PfGW456L13_2483 -2.3 -9.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_66 -2.3 -1.4 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
PfGW456L13_3667 -2.3 -1.4 hypothetical protein compare
PfGW456L13_2597 -2.2 -5.4 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
PfGW456L13_1181 -2.2 -1.5 hypothetical protein compare
PfGW456L13_1853 -2.2 -3.3 Holliday junction DNA helicase RuvB compare
PfGW456L13_3260 -2.2 -1.4 hypothetical protein compare
PfGW456L13_3999 -2.2 -5.1 N-acetylmannosaminyltransferase (EC 2.4.1.187) compare
PfGW456L13_4576 -2.2 -1.7 Transcriptional regulator, ArsR family compare
PfGW456L13_1580 -2.2 -6.1 FIG140336: TPR domain protein compare
PfGW456L13_4946 -2.1 -1.8 hypothetical protein compare
PfGW456L13_4419 -2.1 -1.7 Permeases of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_756 -2.1 -5.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
PfGW456L13_1169 -2.1 -10.9 Coenzyme PQQ synthesis protein F compare
PfGW456L13_4002 -2.1 -6.4 YjbF outer membrane lipoprotein compare
PfGW456L13_2631 -2.1 -2.8 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_4041 -2.1 -2.5 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) compare
PfGW456L13_4171 -2.1 -1.5 FIG00956876: hypothetical protein compare
PfGW456L13_3705 -2.1 -2.4 hypothetical protein compare
PfGW456L13_793 -2.1 -1.8 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_2632 -2.0 -2.0 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_1363 -2.0 -4.1 Rare lipoprotein A precursor compare
PfGW456L13_4001 -2.0 -11.5 Polysaccharide export lipoprotein Wza compare
PfGW456L13_4112 -2.0 -9.7 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
PfGW456L13_2484 -2.0 -5.2 Transcriptional regulators, LysR family compare
PfGW456L13_1842 -2.0 -8.8 Outer membrane porin, OprD family compare
PfGW456L13_4337 -2.0 -1.6 Flagellar biosynthesis protein FliR compare
PfGW456L13_5150 -2.0 -3.1 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_3894 -2.0 -1.6 Integration host factor alpha subunit compare
PfGW456L13_2084 -2.0 -1.8 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_2551 -1.9 -3.0 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_2885 -1.9 -6.5 BarA-associated response regulator UvrY (= GacA = SirA) compare
PfGW456L13_2250 -1.9 -8.7 Probable protease htpX homolog (EC 3.4.24.-) compare
PfGW456L13_2237 -1.9 -2.0 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_3993 -1.9 -5.0 Low molecular weight protein-tyrosine-phosphatase Wzb (EC 3.1.3.48) compare
PfGW456L13_843 -1.9 -1.7 Protein of unknown function DUF484 compare
PfGW456L13_1139 -1.9 -7.3 Malate synthase G (EC 2.3.3.9) compare
PfGW456L13_630 -1.9 -2.8 ABC-type transport system involved in resistance to organic solvents, permease component USSDB6A compare
PfGW456L13_990 -1.9 -2.3 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
PfGW456L13_133 -1.8 -2.5 FIG00956548: hypothetical protein compare
PfGW456L13_4003 -1.8 -4.5 YjbG polysaccharide synthesis-related protein compare
PfGW456L13_139 -1.8 -1.1 LSU ribosomal protein L9p compare
PfGW456L13_3641 -1.8 -1.7 hypothetical protein compare
PfGW456L13_498 -1.8 -0.9 hypothetical protein compare
PfGW456L13_2035 -1.7 -7.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_360 -1.7 -1.5 FIG00956267: hypothetical protein compare
PfGW456L13_949 -1.7 -7.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_5046 -1.7 -5.0 Predicted D-glucarate or D-galactorate regulator, GntR family compare
PfGW456L13_1300 -1.7 -3.9 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
PfGW456L13_1138 -1.7 -1.6 response regulator compare
PfGW456L13_3994 -1.7 -9.7 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
PfGW456L13_5048 -1.7 -2.1 Dna binding response regulator PrrA (RegA) compare
PfGW456L13_4882 -1.7 -2.3 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
PfGW456L13_1523 -1.7 -3.0 Poly(A) polymerase (EC 2.7.7.19) compare
PfGW456L13_2803 -1.7 -6.6 Glyceraldehyde-3-phosphate dehydrogenase, putative compare
PfGW456L13_1644 -1.7 -3.3 Cell division protein MraZ compare
PfGW456L13_1784 -1.6 -1.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_1824 -1.6 -1.4 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_2221 -1.6 -6.7 ErfK/YbiS/YcfS/YnhG family protein compare
PfGW456L13_2608 -1.6 -1.2 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
PfGW456L13_2553 -1.6 -5.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_3532 -1.6 -6.2 FIG00955631: hypothetical protein compare
PfGW456L13_510 -1.6 -1.4 FIG00960943: hypothetical protein compare
PfGW456L13_1888 -1.6 -8.9 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
PfGW456L13_784 -1.5 -4.9 Ribonuclease PH (EC 2.7.7.56) compare
PfGW456L13_4517 -1.5 -7.7 L-aspartate oxidase (EC 1.4.3.16) compare
PfGW456L13_4999 -1.5 -6.2 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_1850 -1.5 -5.6 FIG000859: hypothetical protein YebC compare
PfGW456L13_1284 -1.5 -1.8 Putative transport protein compare
PfGW456L13_4976 -1.5 -1.9 putative membrane protein compare
PfGW456L13_895 -1.5 -3.4 FIG001590: Putative conserved exported protein precursor compare
PfGW456L13_2651 -1.5 -2.4 Cell division protein FtsK compare
PfGW456L13_944 -1.5 -7.3 D-2-hydroxyglutarate dehydrogenase compare
PfGW456L13_140 -1.5 -2.6 FIG003573: hypothetical protein compare
PfGW456L13_1891 -1.5 -5.3 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
PfGW456L13_2357 -1.5 -2.3 Extracellular protease compare
PfGW456L13_3517 -1.4 -3.2 Aldehyde dehydrogenase (EC 1.2.1.3) compare
PfGW456L13_779 -1.4 -6.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_1521 -1.4 -1.8 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source D-Fructose in Pseudomonas fluorescens GW456-L13

For carbon source D-Fructose across organisms