Experiment set2IT044 for Pseudomonas sp. RS175

Compare to:

L-Malic acid carbon source 10 mM

200 most important genes:

  gene name fitness t score description  
PFR28_02823 -5.5 -3.0 3-isopropylmalate dehydratase small subunit 1 compare
PFR28_04278 -4.9 -15.2 Dihydroxy-acid dehydratase compare
PFR28_03363 -4.9 -20.4 Ornithine carbamoyltransferase 1, anabolic compare
PFR28_05015 -4.7 -26.4 Glutamate synthase [NADPH] large chain compare
PFR28_05016 -4.7 -15.8 Glutamate synthase [NADPH] small chain compare
PFR28_01366 -4.6 -12.7 Sulfite reductase [ferredoxin] compare
PFR28_03699 -4.6 -7.7 Acetolactate synthase isozyme 3 large subunit compare
PFR28_03012 -4.6 -10.2 Phosphate acyltransferase compare
PFR28_03697 -4.6 -15.1 Ketol-acid reductoisomerase (NADP(+)) compare
PFR28_02824 -4.6 -7.7 3-isopropylmalate dehydratase large subunit compare
PFR28_02821 -4.6 -19.5 3-isopropylmalate dehydrogenase compare
PFR28_04308 -4.5 -3.1 Amino-acid acetyltransferase compare
PFR28_05105 -4.4 -13.9 Phosphoserine phosphatase SerB2 compare
PFR28_04834 -4.3 -18.1 L-threonine dehydratase biosynthetic IlvA compare
PFR28_04202 -4.2 -7.4 5,10-methylenetetrahydrofolate reductase compare
PFR28_02603 -4.1 -9.7 Siroheme synthase compare
PFR28_02811 -4.1 -9.0 Amidophosphoribosyltransferase compare
PFR28_01365 -4.0 -8.4 hypothetical protein compare
PFR28_03718 -3.8 -5.7 Transcriptional regulatory protein ZraR compare
PFR28_00187 -3.7 -13.7 Histidinol dehydrogenase compare
PFR28_04832 -3.6 -13.3 putative phosphatase compare
PFR28_03698 -3.4 -10.8 Acetolactate synthase isozyme 3 small subunit compare
PFR28_00305 -3.2 -7.9 2-isopropylmalate synthase compare
PFR28_04930 -3.2 -8.9 Imidazole glycerol phosphate synthase subunit HisH compare
PFR28_04245 -3.2 -12.1 Homoserine O-succinyltransferase compare
PFR28_04932 -3.2 -6.3 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PFR28_04246 -3.1 -8.8 Bifunctional methionine biosynthesis protein MetXA/MetW compare
PFR28_04933 -3.1 -4.0 Imidazole glycerol phosphate synthase subunit HisF compare
PFR28_04985 -3.1 -4.3 Phosphoribosyl-ATP pyrophosphatase compare
PFR28_00188 -3.0 -8.5 Histidinol-phosphate aminotransferase compare
PFR28_00186 -3.0 -6.3 ATP phosphoribosyltransferase compare
PFR28_05071 -2.9 -6.5 D-inositol-3-phosphate glycosyltransferase compare
PFR28_02810 -2.9 -12.3 O-succinylhomoserine sulfhydrylase compare
PFR28_03217 -2.9 -3.8 Phosphoribosylformylglycinamidine cyclo-ligase compare
PFR28_05005 -2.8 -9.4 NADP-dependent malic enzyme compare
PFR28_04929 -2.8 -7.7 Histidine biosynthesis bifunctional protein HisB compare
PFR28_03530 -2.7 -2.4 hypothetical protein compare
PFR28_00193 -2.6 -9.8 Sulfate adenylyltransferase subunit 2 compare
PFR28_03635 -2.6 -7.7 Malate:quinone oxidoreductase compare
PFR28_00966 -2.5 -13.9 HTH-type transcriptional regulator CysB compare
PFR28_03218 -2.4 -5.4 Phosphoribosylglycinamide formyltransferase compare
PFR28_04889 -2.3 -6.0 C4-dicarboxylate transport transcriptional regulatory protein DctD conserved
PFR28_00194 -2.3 -8.5 Bifunctional enzyme CysN/CysC compare
PFR28_05125 -2.3 -5.6 ATP phosphoribosyltransferase regulatory subunit compare
PFR28_04842 -2.2 -6.8 D-3-phosphoglycerate dehydrogenase compare
PFR28_04425 -2.2 -7.1 2-iminobutanoate/2-iminopropanoate deaminase compare
PFR28_04986 -2.2 -4.3 Phosphoribosyl-AMP cyclohydrolase compare
PFR28_00098 -2.1 -7.7 Nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
PFR28_03282 -2.1 -6.2 Arginine N-succinyltransferase subunit alpha compare
PFR28_03612 -2.0 -4.0 Cell division protein ZapE compare
PFR28_03721 -2.0 -4.9 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PFR28_03463 -2.0 -2.6 hypothetical protein compare
PFR28_04103 -2.0 -7.3 Biotin synthase compare
PFR28_04874 -2.0 -8.0 Phosphoenolpyruvate carboxykinase (ATP) compare
PFR28_04944 -1.9 -4.2 DNA-binding transcriptional regulator NtrC compare
PFR28_05036 -1.9 -1.2 Acyl carrier protein compare
PFR28_00780 -1.9 -1.4 hypothetical protein compare
PFR28_02608 -1.9 -2.1 DNA translocase FtsK compare
PFR28_03209 -1.8 -3.1 Corrinoid adenosyltransferase compare
PFR28_03388 -1.8 -9.4 Quinolinate synthase A compare
PFR28_03627 -1.8 -2.7 SOS response-associated protein YedK compare
PFR28_05204 -1.8 -4.1 Sulfite reductase [ferredoxin] compare
PFR28_03241 -1.8 -8.3 C4-dicarboxylate transport protein 2 conserved
PFR28_04208 -1.8 -5.6 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PFR28_01154 -1.8 -2.9 hypothetical protein compare
PFR28_01156 -1.7 -5.5 hypothetical protein compare
PFR28_02838 -1.7 -7.3 Aromatic-amino-acid aminotransferase compare
PFR28_04102 -1.6 -7.5 8-amino-7-oxononanoate synthase compare
PFR28_04344 -1.6 -3.7 Exopolyphosphatase compare
PFR28_04072 -1.6 -3.4 Bifunctional folate synthesis protein compare
PFR28_00503 -1.6 -2.1 Histidine transport ATP-binding protein HisP compare
PFR28_03844 -1.5 -4.7 Thiamine-phosphate synthase compare
PFR28_00837 -1.5 -4.5 hypothetical protein compare
PFR28_05232 -1.5 -3.4 hypothetical protein compare
PFR28_00695 -1.5 -1.7 Sulfur carrier protein TusA compare
PFR28_05201 -1.5 -3.2 Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] compare
PFR28_00839 -1.5 -4.4 hypothetical protein compare
PFR28_01450 -1.5 -1.7 hypothetical protein compare
PFR28_04565 -1.5 -8.3 Protein RarD compare
PFR28_01387 -1.5 -1.6 2-iminobutanoate/2-iminopropanoate deaminase compare
PFR28_04712 -1.5 -1.3 Dodecin compare
PFR28_04865 -1.5 -5.4 Glutamate--cysteine ligase compare
PFR28_03653 -1.5 -1.4 Molybdopterin-synthase adenylyltransferase compare
PFR28_03420 -1.4 -3.6 hypothetical protein compare
PFR28_00688 -1.4 -1.3 hypothetical protein compare
PFR28_05205 -1.4 -3.8 Precorrin-8X methylmutase compare
PFR28_02210 -1.4 -1.5 cAMP-activated global transcriptional regulator CRP compare
PFR28_04252 -1.4 -6.0 Thiazole synthase compare
PFR28_01083 -1.3 -5.0 putative copper-importing P-type ATPase A compare
PFR28_03714 -1.3 -8.4 RNA polymerase-binding transcription factor DksA compare
PFR28_03223 -1.3 -8.4 GTP pyrophosphokinase compare
PFR28_01372 -1.3 -2.5 Precorrin-4 C(11)-methyltransferase compare
PFR28_00356 -1.3 -4.3 Protein-glutamate methylesterase/protein-glutamine glutaminase compare
PFR28_03240 -1.3 -1.3 IS110 family transposase ISPfl1 compare
PFR28_05244 -1.3 -7.8 Copper-exporting P-type ATPase compare
PFR28_04473 -1.3 -1.8 DNA-binding protein HU-beta compare
PFR28_04890 -1.3 -5.3 C4-dicarboxylate transport sensor protein DctB compare
PFR28_02484 -1.2 -6.7 UTP--glucose-1-phosphate uridylyltransferase compare
PFR28_04945 -1.2 -3.7 Sensory histidine kinase/phosphatase NtrB compare
PFR28_05139 -1.2 -1.5 hypothetical protein compare
PFR28_03843 -1.2 -3.6 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
PFR28_02788 -1.2 -2.0 hypothetical protein compare
PFR28_00425 -1.2 -7.6 Protein-L-isoaspartate O-methyltransferase compare
PFR28_05212 -1.2 -6.7 Sensor histidine kinase RcsC compare
PFR28_01435 -1.2 -2.0 Response regulator UvrY compare
PFR28_04100 -1.2 -4.8 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PFR28_03281 -1.2 -3.8 Arginine N-succinyltransferase subunit beta compare
PFR28_05176 -1.2 -2.8 Chaperone modulatory protein CbpM compare
PFR28_01230 -1.1 -3.0 Lon protease compare
PFR28_03961 -1.1 -4.1 dTDP-4-dehydrorhamnose reductase compare
PFR28_01460 -1.1 -0.9 Glutamine transport ATP-binding protein GlnQ compare
PFR28_03837 -1.1 -5.3 Leucine-responsive regulatory protein compare
PFR28_04831 -1.1 -2.0 RNA pyrophosphohydrolase compare
PFR28_05199 -1.1 -4.3 Precorrin-6A reductase compare
PFR28_03427 -1.1 -3.8 Sensor histidine kinase RcsC compare
PFR28_03202 -1.1 -0.8 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PFR28_03206 -1.1 -4.4 Cobalamin biosynthesis protein CobD compare
PFR28_00988 -1.1 -4.8 Sensor histidine kinase RcsC compare
PFR28_03229 -1.1 -2.4 hypothetical protein compare
PFR28_00480 -1.1 -3.1 HTH-type transcriptional activator CmpR compare
PFR28_01114 -1.1 -2.8 hypothetical protein compare
PFR28_02386 -1.1 -2.3 Protein hcp1 compare
PFR28_01084 -1.0 -3.5 hypothetical protein compare
PFR28_05091 -1.0 -7.0 Phosphomethylpyrimidine synthase compare
PFR28_02546 -1.0 -3.7 hypothetical protein compare
PFR28_00271 -1.0 -3.6 hypothetical protein compare
PFR28_01157 -1.0 -1.1 hypothetical protein compare
PFR28_04628 -1.0 -2.1 Thiol:disulfide interchange protein DsbA compare
PFR28_04064 -1.0 -2.2 Ribosomal RNA small subunit methyltransferase A compare
PFR28_03192 -1.0 -1.7 hypothetical protein compare
PFR28_03169 -1.0 -5.5 Tail-specific protease compare
PFR28_04343 -1.0 -1.3 Glutamine transport ATP-binding protein GlnQ compare
PFR28_03200 -1.0 -2.9 Adenosylcobinamide-GDP ribazoletransferase compare
PFR28_00126 -1.0 -2.4 Dipeptide transport system permease protein DppC compare
PFR28_02212 -0.9 -1.4 Ubiquinone biosynthesis accessory factor UbiJ compare
PFR28_03412 -0.9 -2.2 Holliday junction ATP-dependent DNA helicase RuvB compare
PFR28_03664 -0.9 -2.0 Ribosome-binding ATPase YchF compare
PFR28_02957 -0.9 -1.3 Fatty acid oxidation complex subunit alpha compare
PFR28_04584 -0.9 -2.6 putative chromosome-partitioning protein ParB compare
PFR28_04633 -0.9 -3.3 Alginate biosynthesis sensor protein KinB compare
PFR28_03625 -0.9 -6.0 Metalloprotease LoiP compare
PFR28_04931 -0.9 -1.7 hypothetical protein compare
PFR28_05078 -0.9 -1.4 hypothetical protein compare
PFR28_04377 -0.9 -2.6 hypothetical protein compare
PFR28_03259 -0.9 -2.0 hypothetical protein compare
PFR28_03369 -0.9 -3.0 Glycerol-3-phosphate regulon repressor compare
PFR28_04782 -0.9 -5.5 hypothetical protein compare
PFR28_04521 -0.8 -2.4 HTH-type transcriptional regulator HexR compare
PFR28_00424 -0.8 -3.1 '5'-nucleotidase SurE' transl_table=11 compare
PFR28_00294 -0.8 -2.5 Dual-specificity RNA methyltransferase RlmN compare
PFR28_00561 -0.8 -2.0 Phosphogluconate dehydratase compare
PFR28_01374 -0.8 -3.3 hypothetical protein compare
PFR28_05207 -0.8 -3.6 Siroheme synthase compare
PFR28_04113 -0.8 -1.8 DNA polymerase III PolC-type compare
PFR28_04232 -0.8 -3.0 Glutathione synthetase compare
PFR28_01155 -0.8 -2.1 hypothetical protein compare
PFR28_04998 -0.8 -2.0 ATP-dependent protease ATPase subunit HslU compare
PFR28_01081 -0.8 -2.2 hypothetical protein compare
PFR28_04936 -0.8 -2.2 Carboxy-terminal processing protease CtpB compare
PFR28_02726 -0.8 -1.7 hypothetical protein compare
PFR28_05058 -0.8 -5.6 hypothetical protein compare
PFR28_02830 -0.8 -1.3 Putative aminoacrylate hydrolase RutD compare
PFR28_01003 -0.8 -2.4 hypothetical protein compare
PFR28_03151 -0.8 -1.1 Septum site-determining protein MinC compare
PFR28_04378 -0.8 -2.2 Tyrosine recombinase XerC compare
PFR28_01381 -0.8 -1.7 hypothetical protein compare
PFR28_01109 -0.7 -2.0 hypothetical protein compare
PFR28_02371 -0.7 -3.1 hypothetical protein compare
PFR28_04737 -0.7 -4.8 Protein YdgA compare
PFR28_02579 -0.7 -2.1 hypothetical protein compare
PFR28_01808 -0.7 -0.8 hypothetical protein compare
PFR28_00332 -0.7 -3.3 Thiol:disulfide interchange protein DsbC compare
PFR28_04498 -0.7 -2.3 Aspartate ammonia-lyase compare
PFR28_04903 -0.7 -2.2 hypothetical protein compare
PFR28_01377 -0.7 -4.1 Aerobic cobaltochelatase subunit CobN compare
PFR28_02822 -0.7 -3.1 putative methyltransferase YcgJ compare
PFR28_02298 -0.7 -1.5 hypothetical protein compare
PFR28_02751 -0.7 -4.3 Translocation and assembly module subunit TamB compare
PFR28_02151 -0.7 -2.9 hypothetical protein compare
PFR28_03208 -0.7 -3.5 Cobyrinate a,c-diamide synthase compare
PFR28_03657 -0.7 -2.4 Beta-barrel assembly-enhancing protease compare
PFR28_04706 -0.7 -2.6 hypothetical protein compare
PFR28_00459 -0.7 -1.9 hypothetical protein compare
PFR28_01294 -0.7 -1.5 hypothetical protein compare
PFR28_03875 -0.7 -0.7 hypothetical protein compare
PFR28_01378 -0.7 -2.2 Magnesium-chelatase 38 kDa subunit compare
PFR28_05046 -0.7 -0.8 hypothetical protein compare
PFR28_03304 -0.7 -0.7 hypothetical protein compare
PFR28_01369 -0.7 -4.1 Methionine synthase compare
PFR28_01730 -0.7 -2.0 hypothetical protein compare
PFR28_03182 -0.7 -1.3 Recombination-associated protein RdgC compare
PFR28_04071 -0.7 -0.7 Multifunctional CCA protein compare
PFR28_00437 -0.7 -2.2 hypothetical protein compare
PFR28_01907 -0.7 -1.4 hypothetical protein compare
PFR28_02241 -0.7 -1.1 Copper-binding lipoprotein NosL compare
PFR28_01933 -0.7 -0.9 Putative tartrate transporter compare
PFR28_02444 -0.7 -2.0 Leucine-responsive regulatory protein compare
PFR28_01375 -0.7 -1.4 hypothetical protein compare
PFR28_03478 -0.7 -4.0 HTH-type transcriptional regulator MetR compare
PFR28_00375 -0.7 -1.5 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Malic acid in Pseudomonas sp. RS175

For carbon source L-Malic acid across organisms