Experiment set2IT041 for Escherichia coli BW25113

Compare to:

LB with Thallium(I) acetate 0.0625 mg/ml

200 most important genes:

  gene name fitness t score description  
b1105 ycfM -4.1 -3.9 predicted outer membrane lipoprotein (NCBI) compare
b0149 mrcB -4.0 -5.5 penicillin-binding protein 1b (NCBI) compare
b0920 ycbC -3.4 -5.1 conserved inner membrane protein (NCBI) compare
b3792 wzxE -3.2 -7.6 O-antigen translocase (NCBI) compare
b3414 gntY -2.5 -6.2 predicted gluconate transport associated protein (NCBI) compare
b0737 tolQ -2.4 -3.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0739 tolA -2.4 -4.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2297 pta -2.2 -1.5 phosphate acetyltransferase (NCBI) compare
b3405 ompR -2.1 -4.9 osmolarity response regulator (NCBI) compare
b0088 murD -2.1 -2.6 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1279 yciS -2.1 -2.1 conserved inner membrane protein (NCBI) compare
b0740 tolB -2.0 -4.4 translocation protein TolB precursor (NCBI) compare
b0741 pal -2.0 -4.6 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2699 recA -1.8 -1.7 recombinase A (NCBI) compare
b3183 obgE -1.8 -2.0 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2820 recB -1.8 -2.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1863 ruvC -1.8 -3.5 Holliday junction resolvase (NCBI) compare
b0738 tolR -1.8 -3.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0049 apaH -1.7 -5.1 diadenosinetetraphosphatase (NCBI) compare
b4458 oxyS -1.7 -1.0 global regulatory RNA (NCBI) compare
b3863 polA -1.6 -1.1 DNA polymerase I (NCBI) compare
b3839 tatC -1.6 -7.8 TatABCE protein translocation system subunit (NCBI) compare
b1860 ruvB -1.6 -1.9 Holliday junction DNA helicase B (NCBI) compare
b1361 ydaW -1.6 -1.5 orf, hypothetical protein (VIMSS) compare
b4552 yrhC -1.6 -2.2 no description compare
b2055 wcaE -1.6 -3.6 predicted glycosyl transferase (NCBI) compare
b3742 mioC -1.5 -4.2 flavodoxin (NCBI) compare
b1358 ydaT -1.5 -2.0 Rac prophage; predicted protein (NCBI) compare
b4546 ypeB -1.4 -1.6 hypothetical protein (NCBI) compare
b1192 ldcA -1.4 -4.1 L,D-carboxypeptidase A (NCBI) compare
b2822 recC -1.4 -4.1 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0439 lon -1.4 -4.2 DNA-binding ATP-dependent protease La (NCBI) compare
b0500 ybbD -1.4 -1.7 hypothetical protein (RefSeq) compare
b1144 ymfJ -1.4 -2.5 orf, hypothetical protein (VIMSS) compare
b1167 ymgC -1.4 -2.0 hypothetical protein (NCBI) compare
b0890 ftsK -1.4 -5.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2343 b2343 -1.3 -1.7 orf, hypothetical protein (VIMSS) compare
b0429 cyoD -1.3 -3.4 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b2436 hemF -1.3 -3.7 coproporphyrinogen III oxidase (NCBI) compare
b3791 rffA -1.3 -6.3 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1290 sapF -1.3 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4410 ecnA -1.3 -1.3 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1292 sapC -1.3 -1.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0726 sucA -1.3 -2.9 alpha-ketoglutarate decarboxylase (NCBI) compare
b1576 ydfD -1.3 -2.5 Qin prophage; predicted protein (NCBI) compare
b2910 zapA -1.3 -3.8 protein that localizes to the cytokinetic ring (NCBI) compare
b2642 yfjW -1.3 -2.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b4481 rffT -1.3 -5.0 4-alpha-L-fucosyltransferase (NCBI) compare
b3613 yibP -1.2 -4.5 putative membrane protein (VIMSS) compare
b2938 speA -1.2 -7.0 arginine decarboxylase (NCBI) compare
b2516 yfgA -1.2 -5.6 hypothetical protein (NCBI) compare
b3290 trkA -1.2 -2.8 potassium transporter peripheral membrane component (NCBI) compare
b1063 yceB -1.2 -2.3 predicted lipoprotein (NCBI) compare
b2567 rnc -1.2 -1.8 ribonuclease III (NCBI) compare
b3055 htrG -1.2 -5.9 predicted signal transduction protein (SH3 domain) (NCBI) compare
b4418 sraB -1.2 -1.5 unknown RNA (NCBI) compare
b0118 acnB -1.2 -2.5 aconitate hydratase (NCBI) compare
b2650 ypjC -1.2 -2.1 hypothetical protein (RefSeq) compare
b4171 miaA -1.2 -3.9 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1499 ydeO -1.2 -2.2 predicted DNA-binding transcriptional acfivator (NCBI) compare
b3204 ptsN -1.2 -4.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b1343 dbpA -1.2 -3.5 ATP-dependent RNA helicase, specific for 23S rRNA (NCBI) compare
b3725 pstB -1.1 -2.2 phosphate transporter subunit (NCBI) compare
b3462 ftsX -1.1 -4.6 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3463 ftsE -1.1 -3.3 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0630 lipB -1.1 -1.9 protein of lipoate biosynthesis (VIMSS) compare
b0782 moaB -1.1 -1.9 molybdopterin biosynthesis protein B (NCBI) compare
b0605 ahpC -1.1 -4.0 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1176 minC -1.1 -2.9 septum formation inhibitor (NCBI) compare
b4441 glmY -1.1 -1.6 sRNA activator of glmS mRNA (RefSeq) compare
b4453 ldrD -1.1 -1.8 toxic polypeptide, small (NCBI) compare
b0866 ybjQ -1.1 -1.2 hypothetical protein (NCBI) compare
b1058 yceO -1.1 -1.6 hypothetical protein (NCBI) compare
b4402 yjjY -1.1 -1.2 hypothetical protein (NCBI) compare
b3811 xerC -1.1 -1.8 site-specific tyrosine recombinase XerC (NCBI) compare
b1271 yciK -1.1 -2.3 short chain dehydrogenase (NCBI) compare
b4375 prfC -1.0 -4.4 peptide chain release factor 3 (NCBI) compare
b2259 pmrD -1.0 -1.5 polymyxin resistance protein B (VIMSS) compare
b4148 sugE -1.0 -2.9 suppresses groEL, may be chaperone (VIMSS) compare
b1259 yciG -1.0 -1.8 orf, hypothetical protein (VIMSS) compare
b1252 tonB -1.0 -2.2 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b4596 yciZ -1.0 -1.3 hypothetical protein (RefSeq) compare
b4128 yjdK -1.0 -2.9 hypothetical protein (NCBI) compare
b3472 b3472 -1.0 -4.7 orf, hypothetical protein (VIMSS) compare
b1730 ydjO -1.0 -2.5 predicted protein (RefSeq) compare
b3098 yqjD -1.0 -2.3 hypothetical protein (NCBI) compare
b3652 recG -1.0 -5.6 ATP-dependent DNA helicase (NCBI) compare
b4202 rpsR -1.0 -1.5 30S ribosomal protein S18 (NCBI) compare
b1942 fliJ -0.9 -1.1 flagellar biosynthesis chaperone (NCBI) compare
b0705 ybfL -0.9 -2.5 putative receptor protein (VIMSS) compare
b3120 yhaB -0.9 -2.8 orf, hypothetical protein (VIMSS) compare
b1293 sapB -0.9 -1.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4046 yjbK -0.9 -3.9 putative regulator (VIMSS) compare
b4551 yheV -0.9 -2.0 hypothetical protein (NCBI) compare
b0721 sdhC -0.9 -2.8 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b2912 ygfA -0.9 -1.9 putative ligase (VIMSS) compare
b0427 yajR -0.9 -4.9 putative transport protein (VIMSS) compare
b3404 envZ -0.9 -5.7 osmolarity sensor protein (NCBI) compare
b1257 yciE -0.9 -1.8 hypothetical protein (NCBI) compare
b4647 mokA -0.9 -1.4 no description compare
b0603 ybdO -0.9 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b2340 sixA -0.9 -2.6 phosphohistidine phosphatase (NCBI) compare
b1823 cspC -0.9 -1.9 stress protein, member of the CspA-family (NCBI) compare
b1304 pspA -0.9 -2.7 regulatory protein for phage-shock-protein operon (NCBI) compare
b3790 rffC -0.8 -3.2 TDP-fucosamine acetyltransferase (RefSeq) compare
b4369 leuP -0.8 -1.6 tRNA-Leu (NCBI) compare
b2894 xerD -0.8 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b4543 ypaA -0.8 -1.6 predicted protein (NCBI) compare
b2287 nuoB -0.8 -2.4 NADH dehydrogenase subunit B (NCBI) compare
b2175 spr -0.8 -2.2 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b2330 yfcB -0.8 -1.5 putative adenine-specific methylase (VIMSS) compare
b1861 ruvA -0.8 -1.3 Holliday junction DNA helicase motor protein (NCBI) compare
b3121 yhaC -0.8 -1.6 hypothetical protein (NCBI) compare
b0683 fur -0.8 -1.2 ferric uptake regulator (NCBI) compare
b2054 wcaF -0.8 -3.9 predicted acyl transferase (NCBI) compare
b1604 ydgH -0.8 -3.0 hypothetical protein (NCBI) compare
b2110 yehC -0.8 -2.3 predicted periplasmic pilin chaperone (NCBI) compare
b1038 csgF -0.8 -1.9 predicted transport protein (NCBI) compare
b2215 ompC -0.8 -4.6 outer membrane porin protein C (NCBI) compare
b3026 qseC -0.8 -2.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0850 ybjC -0.8 -2.1 predicted inner membrane protein (NCBI) compare
b2006 yeeW -0.8 -2.2 CP4-44 prophage; predicted protein (RefSeq) compare
b0431 cyoB -0.8 -4.5 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b4325 yjiC -0.8 -2.8 orf, hypothetical protein (VIMSS) compare
b2037 rfbX -0.8 -5.2 predicted polisoprenol-linked O-antigen transporter (NCBI) compare
b2279 nuoK -0.8 -1.5 NADH dehydrogenase subunit K (NCBI) compare
b3977 tyrU -0.8 -0.8 tRNA-Tyr (NCBI) compare
b2962 yggX -0.8 -1.5 hypothetical protein (NCBI) compare
b0407 yajC -0.7 -1.8 preprotein translocase subunit YajC (NCBI) compare
b2352 yfdI -0.7 -2.5 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b2892 recJ -0.7 -4.1 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b2531 iscR -0.7 -1.1 DNA-binding transcriptional repressor (NCBI) compare
b0450 glnK -0.7 -1.1 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b2830 nudH -0.7 -1.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b1446 ydcY -0.7 -1.1 hypothetical protein (NCBI) compare
b1104 ycfL -0.7 -1.3 hypothetical protein (NCBI) compare
b4590 ybfK -0.7 -2.8 hypothetical protein (RefSeq) compare
b0131 panD -0.7 -2.0 aspartate 1-decarboxylase precursor (NCBI) compare
b1497 b1497 -0.7 -1.8 putative enzyme (VIMSS) compare
b2754 ygbF -0.7 -1.3 orf, hypothetical protein (VIMSS) compare
b0013 yaaI -0.7 -2.5 hypothetical protein (NCBI) compare
b1548 nohA -0.7 -1.6 Qin prophage; predicted packaging protein (RefSeq) compare
b2808 gcvA -0.7 -2.4 DNA-binding transcriptional dual regulator (NCBI) compare
b1273 yciN -0.7 -1.2 hypothetical protein (NCBI) compare
b1926 fliT -0.7 -1.9 predicted chaperone (NCBI) compare
b0015 dnaJ -0.7 -4.1 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b3611 yibN -0.7 -2.4 predicted rhodanese-related sulfurtransferase (NCBI) compare
b3726 pstA -0.7 -3.0 phosphate transporter subunit (NCBI) compare
b4374 yjjG -0.7 -3.1 nucleotidase (NCBI) compare
b3651 trmH -0.7 -3.4 tRNA (Guanosine-2'-O-)-methyltransferase (NCBI) compare
b4414 tff -0.7 -1.9 unknown RNA (NCBI) compare
b1007 b1007 -0.7 -0.8 orf, hypothetical protein (VIMSS) compare
b1595 ynfL -0.7 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b1090 plsX -0.7 -2.3 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b0386 proC -0.7 -3.0 pyrroline-5-carboxylate reductase (NCBI) compare
b1882 cheY -0.7 -1.0 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b3781 trxA -0.7 -2.0 thioredoxin 1 (VIMSS) compare
b0279 yagM -0.7 -2.9 CP4-6 prophage; predicted protein (NCBI) compare
b0722 sdhD -0.7 -2.0 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b1382 ynbE -0.7 -1.2 predicted lipoprotein (NCBI) compare
b0564 appY -0.7 -0.6 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1291 sapD -0.7 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2286 nuoC -0.7 -2.7 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1147 ymfL -0.7 -1.4 e14 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b1842 holE -0.7 -1.2 DNA polymerase III, theta subunit (NCBI) compare
b1143 ymfI -0.7 -0.6 orf, hypothetical protein (VIMSS) compare
b2428 yfeU -0.7 -2.0 N-acetylmuramic acid-6-phosphate etherase (NCBI) compare
b0783 moaC -0.7 -2.5 molybdenum cofactor biosynthesis protein C (NCBI) compare
b1305 pspB -0.7 -1.4 phage shock protein B (NCBI) compare
b0849 grxA -0.7 -1.0 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) (NCBI) compare
b2570 rseC -0.7 -2.3 RseC protein involved in reduction of the SoxR iron-sulfur cluster (NCBI) compare
b1434 ydcN -0.7 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1008 ycdI -0.7 -1.9 hypothetical protein (NCBI) compare
b0436 tig -0.7 -3.5 trigger factor (NCBI) compare
b3912 cpxR -0.7 -3.9 DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) compare
b0218 yafU -0.7 -2.0 predicted inner membrane protein (RefSeq) compare
b0806 ybiM -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b0028 fkpB -0.6 -2.2 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare
b0966 hspQ -0.6 -3.1 DNA-binding protein, hemimethylated (RefSeq) compare
b4598 yncL -0.6 -1.2 hypothetical protein (RefSeq) compare
b2021 hisC -0.6 -2.5 histidinol-phosphate aminotransferase (NCBI) compare
b2113 mrp -0.6 -2.4 putative ATPase (VIMSS) compare
b3504 yhiS -0.6 -1.8 hypothetical protein (RefSeq) compare
b0113 pdhR -0.6 -2.1 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b1182 hlyE -0.6 -1.5 hemolysin E (VIMSS) compare
b2569 lepA -0.6 -2.1 GTP-binding protein LepA (NCBI) compare
b2744 surE -0.6 -3.2 acid phosphatase (NCBI) compare
b1390 paaC -0.6 -1.8 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b0428 cyoE -0.6 -2.6 protoheme IX farnesyltransferase (NCBI) compare
b2637 yfjT -0.6 -1.6 CP4-57 prophage; predicted protein (NCBI) compare
b2620 smpB -0.6 -1.0 SsrA-binding protein (NCBI) compare
b3387 dam -0.6 -4.3 DNA adenine methylase (NCBI) compare
b3609 secB -0.6 -1.8 export protein SecB (NCBI) compare
b3169 nusA -0.6 -1.2 transcription elongation factor NusA (NCBI) compare
b2435 amiA -0.6 -1.8 N-acetylmuramoyl-l-alanine amidase I (NCBI) compare
b3341 rpsG -0.6 -0.7 30S ribosomal protein S7 (NCBI) compare
b2074 b2074 -0.6 -2.4 putative membrane protein (VIMSS) compare
b0210 yafE -0.6 -1.4 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b3963 fabR -0.6 -3.8 DNA-binding transcriptional repressor (RefSeq) compare
b3620 rfaF -0.6 -2.3 ADP-heptose:LPS heptosyltransferase II (NCBI) compare


Specific Phenotypes

For 2 genes in this experiment

For stress Thallium(I) acetate in Escherichia coli BW25113

For stress Thallium(I) acetate across organisms