Experiment set2IT023 for Escherichia coli BW25113

Compare to:

LB with Sodium Chloride 750 mM

200 most important genes:

  gene name fitness t score description  
b2217 rcsB -4.4 -5.9 DNA-binding response regulator in two-component regulatory system with RcsC and YojN (NCBI) compare
b4111 proP -4.2 -2.9 proline/glycine betaine transporter (NCBI) compare
b3181 greA -4.1 -2.8 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b1105 ycfM -3.9 -2.6 predicted outer membrane lipoprotein (NCBI) compare
b2571 rseB -3.7 -4.3 periplasmic negative regulator of sigmaE (NCBI) compare
b0196 rcsF -3.7 -4.9 predicted outer membrane protein, signal (NCBI) compare
b1129 phoQ -3.6 -7.4 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1192 ldcA -3.5 -3.3 L,D-carboxypeptidase A (NCBI) compare
b2055 wcaE -3.2 -4.7 predicted glycosyl transferase (NCBI) compare
b3341 rpsG -3.2 -2.1 30S ribosomal protein S7 (NCBI) compare
b1130 phoP -3.2 -6.7 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b0737 tolQ -3.1 -3.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2061 wzb -3.0 -2.5 protein-tyrosine phosphatase (NCBI) compare
b0019 nhaA -2.9 -3.4 pH-dependent sodium/proton antiporter (NCBI) compare
b0149 mrcB -2.9 -6.6 penicillin-binding protein 1b (NCBI) compare
b1863 ruvC -2.9 -4.0 Holliday junction resolvase (NCBI) compare
b1103 ycfF -2.8 -1.9 orf, hypothetical protein (VIMSS) compare
b3082 ygjM -2.8 -2.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b1861 ruvA -2.8 -1.8 Holliday junction DNA helicase motor protein (NCBI) compare
b2046 wzxC -2.8 -7.4 colanic acid exporter (NCBI) compare
b0145 dksA -2.6 -3.0 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2028 ugd -2.6 -11.9 UDP-glucose 6-dehydrogenase (NCBI) compare
b0920 ycbC -2.5 -5.4 conserved inner membrane protein (NCBI) compare
b2056 wcaD -2.5 -10.4 predicted colanic acid polymerase (NCBI) compare
b0740 tolB -2.5 -2.4 translocation protein TolB precursor (NCBI) compare
b0739 tolA -2.4 -2.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2059 wcaA -2.4 -5.2 predicted glycosyl transferase (NCBI) compare
b2062 wza -2.4 -9.1 lipoprotein required for capsular polysaccharide translocation through the outer membrane (NCBI) compare
b2060 b2060 -2.3 -6.6 orf, hypothetical protein (VIMSS) compare
b0960 b0960 -2.3 -10.6 orf, hypothetical protein (VIMSS) compare
b0841 ybjG -2.3 -3.5 undecaprenyl pyrophosphate phosphatase (NCBI) compare
b0738 tolR -2.3 -2.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3414 gntY -2.2 -5.0 predicted gluconate transport associated protein (NCBI) compare
b1860 ruvB -2.1 -1.8 Holliday junction DNA helicase B (NCBI) compare
b4171 miaA -2.1 -5.3 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2431 b2431 -2.1 -7.2 orf, hypothetical protein (VIMSS) compare
b0500 ybbD -2.1 -2.5 hypothetical protein (RefSeq) compare
b3121 yhaC -2.1 -2.6 hypothetical protein (NCBI) compare
b0433 ampG -2.1 -11.5 muropeptide transporter (NCBI) compare
b2576 srmB -2.0 -2.6 ATP-dependent RNA helicase (NCBI) compare
b4402 yjjY -2.0 -1.8 hypothetical protein (NCBI) compare
b2679 proX -2.0 -4.0 glycine betaine transporter subunit (NCBI) compare
b2567 rnc -2.0 -1.3 ribonuclease III (NCBI) compare
b3962 udhA -1.9 -8.1 putative oxidoreductase (VIMSS) compare
b2830 nudH -1.8 -1.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b0759 galE -1.8 -5.0 UDP-galactose-4-epimerase (VIMSS) compare
b0088 murD -1.7 -2.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b3169 nusA -1.7 -3.1 transcription elongation factor NusA (NCBI) compare
b3839 tatC -1.7 -6.8 TatABCE protein translocation system subunit (NCBI) compare
b3398 yrfF -1.7 -2.6 predicted inner membrane protein (NCBI) compare
b3613 yibP -1.7 -3.5 putative membrane protein (VIMSS) compare
b3811 xerC -1.7 -2.2 site-specific tyrosine recombinase XerC (NCBI) compare
b4172 hfq -1.7 -1.8 RNA-binding protein Hfq (NCBI) compare
b4631 ykgQ -1.7 -2.3 no description compare
b1576 ydfD -1.7 -2.7 Qin prophage; predicted protein (NCBI) compare
b3021 ygiT -1.7 -3.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0741 pal -1.6 -2.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2938 speA -1.6 -8.2 arginine decarboxylase (NCBI) compare
b3725 pstB -1.6 -1.8 phosphate transporter subunit (NCBI) compare
b2894 xerD -1.6 -1.4 site-specific tyrosine recombinase XerD (NCBI) compare
b2054 wcaF -1.6 -5.3 predicted acyl transferase (NCBI) compare
b2045 wcaK -1.6 -7.2 predicted pyruvyl transferase (NCBI) compare
b1086 rluC -1.6 -4.7 23S rRNA pseudouridylate synthase (NCBI) compare
b0683 fur -1.6 -1.7 ferric uptake regulator (NCBI) compare
b3935 priA -1.6 -2.9 primosome assembly protein PriA (NCBI) compare
b3816 corA -1.6 -5.1 magnesium/nickel/cobalt transporter (NCBI) compare
b4414 tff -1.6 -2.4 unknown RNA (NCBI) compare
b0450 glnK -1.6 -2.7 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b3728 pstS -1.6 -3.5 phosphate transporter subunit (NCBI) compare
b3790 rffC -1.5 -4.1 TDP-fucosamine acetyltransferase (RefSeq) compare
b0226 dinJ -1.5 -3.4 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b1830 prc -1.5 -4.8 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b1856 yebA -1.5 -5.3 orf, hypothetical protein (VIMSS) compare
b1551 b1551 -1.5 -2.4 orf, hypothetical protein (VIMSS) compare
b1182 hlyE -1.5 -2.5 hemolysin E (VIMSS) compare
b1160 elbA -1.5 -2.7 hypothetical protein (NCBI) compare
b3844 fre -1.5 -3.8 NAD(P)H-flavin reductase (NCBI) compare
b3764 yifE -1.5 -3.7 hypothetical protein (NCBI) compare
b2846 yqeH -1.5 -2.9 orf, hypothetical protein (VIMSS) compare
b4481 rffT -1.5 -4.9 4-alpha-L-fucosyltransferase (NCBI) compare
b0053 surA -1.4 -2.3 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3791 rffA -1.4 -5.5 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1361 ydaW -1.4 -1.3 orf, hypothetical protein (VIMSS) compare
b1728 ydjM -1.4 -2.9 predicted inner membrane protein regulated by LexA (RefSeq) compare
b0720 gltA -1.4 -4.1 citrate synthase (NCBI) compare
b2424 cysU -1.4 -2.2 sulfate/thiosulfate transporter subunit (NCBI) compare
b4201 priB -1.4 -2.5 primosomal replication protein N (NCBI) compare
b0890 ftsK -1.4 -4.9 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1685 ydiH -1.4 -1.8 predicted protein (RefSeq) compare
b2058 wcaB -1.4 -1.6 predicted acyl transferase (NCBI) compare
b4651 yibW -1.4 -1.7 no description compare
b1347 ydaC -1.4 -2.3 Rac prophage; predicted protein (NCBI) compare
b4128 yjdK -1.4 -3.9 hypothetical protein (NCBI) compare
b3442 yhhZ -1.4 -2.3 hypothetical protein (NCBI) compare
b0603 ybdO -1.3 -3.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b3035 tolC -1.3 -5.7 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3652 recG -1.3 -6.0 ATP-dependent DNA helicase (NCBI) compare
b0249 ykfF -1.3 -2.1 CP4-6 prophage; predicted protein (NCBI) compare
b4146 yjeK -1.3 -2.7 predicted lysine aminomutase (NCBI) compare
b1434 ydcN -1.3 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b2276 nuoN -1.3 -3.9 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3462 ftsX -1.3 -3.7 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3792 wzxE -1.3 -5.8 O-antigen translocase (NCBI) compare
b2057 wcaC -1.3 -3.4 predicted glycosyl transferase (NCBI) compare
b0742 ybgF -1.3 -3.7 hypothetical protein (NCBI) compare
b3162 deaD -1.3 -3.7 inducible ATP-independent RNA helicase (VIMSS) compare
b3786 rffE -1.3 -7.6 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3463 ftsE -1.3 -2.8 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1084 rne -1.2 -3.3 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b1841 yobA -1.2 -1.5 hypothetical protein (NCBI) compare
b3150 yraP -1.2 -3.9 hypothetical protein (NCBI) compare
b0726 sucA -1.2 -2.9 alpha-ketoglutarate decarboxylase (NCBI) compare
b3784 rfe -1.2 -7.3 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3778 rep -1.2 -5.7 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1961 dcm -1.2 -1.6 DNA cytosine methylase (NCBI) compare
b4177 purA -1.2 -2.4 adenylosuccinate synthetase (NCBI) compare
b4570 lomR -1.2 -2.3 no description compare
b2279 nuoK -1.2 -2.0 NADH dehydrogenase subunit K (NCBI) compare
b4543 ypaA -1.2 -2.6 predicted protein (NCBI) compare
b2784 relA -1.2 -5.6 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b3787 rffD -1.2 -6.5 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b2501 ppk -1.2 -5.7 polyphosphate kinase (NCBI) compare
b1286 rnb -1.2 -2.3 exoribonuclease II (NCBI) compare
b0705 ybfL -1.2 -2.3 putative receptor protein (VIMSS) compare
b4416 rybA -1.2 -1.8 unknown RNA (NCBI) compare
b1273 yciN -1.2 -1.4 hypothetical protein (NCBI) compare
b1677 lpp -1.1 -2.1 murein lipoprotein (NCBI) compare
b1919 yedO -1.1 -2.7 putative 1-aminocyclopropane-1-carboxylate deaminase (VIMSS) compare
b2808 gcvA -1.1 -3.4 DNA-binding transcriptional dual regulator (NCBI) compare
b0632 dacA -1.1 -4.8 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b1497 b1497 -1.1 -2.8 putative enzyme (VIMSS) compare
b3101 yqjF -1.1 -2.2 orf, hypothetical protein (VIMSS) compare
b4413 sokC -1.1 -1.3 regulatory antisense RNA (NCBI) compare
b3741 gidA -1.1 -4.6 glucose-inhibited division protein A (NCBI) compare
b2218 rcsC -1.1 -5.9 hybrid sensory kinase in two-component regulatory system with RcsB and YojN (RefSeq) compare
b2286 nuoC -1.1 -3.4 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b2937 speB -1.1 -4.0 agmatinase (NCBI) compare
b2847 yqeI -1.1 -4.2 predicted transcriptional regulator (NCBI) compare
b2426 ucpA -1.1 -1.6 putative oxidoreductase (VIMSS) compare
b2620 smpB -1.1 -1.3 SsrA-binding protein (NCBI) compare
b3147 yraM -1.1 -6.1 hypothetical protein (NCBI) compare
b1175 minD -1.1 -3.6 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3863 polA -1.1 -0.7 DNA polymerase I (NCBI) compare
b0623 cspE -1.1 -1.6 cold shock protein E (NCBI) compare
b0082 mraW -1.1 -2.2 S-adenosyl-methyltransferase (NCBI) compare
b3387 dam -1.1 -6.5 DNA adenine methylase (NCBI) compare
b1097 yceG -1.1 -3.9 predicted aminodeoxychorismate lyase (NCBI) compare
b2044 wcaL -1.0 -2.4 predicted glycosyl transferase (NCBI) compare
b4503 yafF -1.0 -1.6 no description compare
b1252 tonB -1.0 -2.3 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b0049 apaH -1.0 -3.4 diadenosinetetraphosphatase (NCBI) compare
b3838 tatB -1.0 -4.6 sec-independent translocase (NCBI) compare
b0247 ykfG -1.0 -1.2 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b1613 manA -1.0 -1.7 mannose-6-phosphate isomerase (VIMSS) compare
b3977 tyrU -1.0 -1.3 tRNA-Tyr (NCBI) compare
b1749 xthA -1.0 -2.3 exonuclease III (NCBI) compare
b2516 yfgA -1.0 -4.2 hypothetical protein (NCBI) compare
b1257 yciE -1.0 -2.0 hypothetical protein (NCBI) compare
b3164 pnp -1.0 -1.8 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3206 npr -1.0 -3.1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b3032 cpdA -1.0 -4.5 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b0641 rlpB -1.0 -1.2 minor lipoprotein (NCBI) compare
b4176 yjeT -1.0 -2.3 conserved inner membrane protein (NCBI) compare
b2625 yfjI -1.0 -3.9 CP4-57 prophage; predicted protein (NCBI) compare
b3813 uvrD -1.0 -6.6 DNA-dependent ATPase I and helicase II (NCBI) compare
b2352 yfdI -1.0 -2.5 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b2110 yehC -1.0 -2.4 predicted periplasmic pilin chaperone (NCBI) compare
b4590 ybfK -1.0 -3.4 hypothetical protein (RefSeq) compare
b2052 fcl -1.0 -3.3 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase (NCBI) compare
b1176 minC -1.0 -2.0 septum formation inhibitor (NCBI) compare
b0463 acrA -0.9 -4.8 multidrug efflux system (NCBI) compare
b3961 oxyR -0.9 -5.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1104 ycfL -0.9 -1.2 hypothetical protein (NCBI) compare
b4687 shoB -0.9 -2.4 toxic membrane protein (RefSeq) compare
b2278 nuoL -0.9 -4.5 NADH dehydrogenase subunit L (NCBI) compare
b2053 gmd -0.9 -3.4 GDP-D-mannose dehydratase, NAD(P)-binding (NCBI) compare
b1409 ynbB -0.9 -3.6 predicted CDP-diglyceride synthase (NCBI) compare
b2277 nuoM -0.9 -3.1 NADH dehydrogenase subunit M (NCBI) compare
b1582 ynfA -0.9 -1.7 hypothetical protein (NCBI) compare
b0407 yajC -0.9 -1.6 preprotein translocase subunit YajC (NCBI) compare
b2048 cpsG -0.9 -2.8 phosphomannomutase (NCBI) compare
b1040 csgD -0.9 -3.2 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b4041 plsB -0.9 -1.5 glycerol-3-phosphate acyltransferase (VIMSS) compare
b0585 fes -0.9 -3.2 enterobactin/ferric enterobactin esterase (NCBI) compare
b3794 rffM -0.9 -3.5 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b3199 yrbK -0.9 -1.4 hypothetical protein (NCBI) compare
b2216 rcsD -0.9 -5.2 phosphotransfer intermediate protein in two-component regulatory system with RcsBC (NCBI) compare
b0780 ybhK -0.9 -3.1 predicted transferase with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b1806 yeaY -0.9 -2.5 predicted lipoprotein (NCBI) compare
b1726 yniB -0.9 -1.7 predicted inner membrane protein (NCBI) compare
b4249 yjgI -0.9 -3.2 predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b4480 hdfR -0.9 -2.7 transcriptional regulator HdfR (NCBI) compare
b3026 qseC -0.9 -2.5 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4202 rpsR -0.9 -1.0 30S ribosomal protein S18 (NCBI) compare
b4509 ylcG -0.9 -1.9 DLP12 prophage; predicted protein (NCBI) compare
b1382 ynbE -0.9 -1.2 predicted lipoprotein (NCBI) compare
b1392 paaE -0.9 -3.0 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b4568 ytjA -0.9 -1.1 predicted protein (RefSeq) compare
b3706 trmE -0.9 -3.5 tRNA modification GTPase (NCBI) compare
b2565 recO -0.9 -2.4 DNA repair protein RecO (NCBI) compare


Specific Phenotypes

For 13 genes in this experiment

For stress Sodium Chloride in Escherichia coli BW25113

For stress Sodium Chloride across organisms