Experiment set2IT018 for Escherichia coli BW25113

Compare to:

LB with Sodium Chlorite 0.4 mM

200 most important genes:

  gene name fitness t score description  
b2168 fruK -3.4 -3.1 1-phosphofructokinase (NCBI) compare
b2016 yeeZ -2.8 -7.3 predicted epimerase, with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b3169 nusA -2.7 -3.8 transcription elongation factor NusA (NCBI) compare
b2688 gshA -2.4 -7.7 glutamate--cysteine ligase (NCBI) compare
b4172 hfq -2.4 -1.6 RNA-binding protein Hfq (NCBI) compare
b0145 dksA -2.3 -3.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3844 fre -2.2 -4.6 NAD(P)H-flavin reductase (NCBI) compare
b0080 fruR -2.2 -4.4 DNA-binding transcriptional dual regulator (NCBI) compare
b1861 ruvA -2.1 -2.4 Holliday junction DNA helicase motor protein (NCBI) compare
b2830 nudH -2.0 -1.3 dinucleoside polyphosphate hydrolase (NCBI) compare
b0683 fur -1.9 -2.0 ferric uptake regulator (NCBI) compare
b2576 srmB -1.8 -3.1 ATP-dependent RNA helicase (NCBI) compare
b0912 ihfB -1.8 -3.5 integration host factor subunit beta (NCBI) compare
b3807 cyaY -1.8 -6.5 frataxin-like protein (NCBI) compare
b1347 ydaC -1.7 -2.8 Rac prophage; predicted protein (NCBI) compare
b0053 surA -1.7 -2.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0737 tolQ -1.6 -3.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3463 ftsE -1.6 -2.4 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3741 gidA -1.5 -5.3 glucose-inhibited division protein A (NCBI) compare
b1361 ydaW -1.5 -1.3 orf, hypothetical protein (VIMSS) compare
b3121 yhaC -1.5 -2.1 hypothetical protein (NCBI) compare
b4201 priB -1.5 -2.6 primosomal replication protein N (NCBI) compare
b0726 sucA -1.5 -3.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b0001 thrL -1.5 -2.5 thr operon leader peptide (NCBI) compare
b3935 priA -1.4 -2.5 primosome assembly protein PriA (NCBI) compare
b3237 argR -1.4 -3.6 arginine repressor (NCBI) compare
b0888 trxB -1.4 -2.8 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0784 moaD -1.4 -2.5 molybdopterin synthase, small subunit (NCBI) compare
b3162 deaD -1.4 -3.8 inducible ATP-independent RNA helicase (VIMSS) compare
b3706 trmE -1.4 -4.7 tRNA modification GTPase (NCBI) compare
b2953 yggU -1.3 -1.4 orf, hypothetical protein (VIMSS) compare
b2055 wcaE -1.3 -2.5 predicted glycosyl transferase (NCBI) compare
b1818 manY -1.3 -2.1 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1984 asnW -1.3 -1.3 tRNA-Asn (NCBI) compare
b3366 nirD -1.3 -2.8 nitrite reductase small subunit (NCBI) compare
b1863 ruvC -1.3 -2.9 Holliday junction resolvase (NCBI) compare
b1241 adhE -1.3 -5.6 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) compare
b3725 pstB -1.3 -2.0 phosphate transporter subunit (NCBI) compare
b1497 b1497 -1.2 -3.3 putative enzyme (VIMSS) compare
b0097 yacA -1.2 -2.7 orf, hypothetical protein (VIMSS) compare
b3462 ftsX -1.2 -3.8 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2390 ypeC -1.2 -2.9 hypothetical protein (NCBI) compare
b3652 recG -1.2 -5.7 ATP-dependent DNA helicase (NCBI) compare
b0450 glnK -1.2 -2.3 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b1252 tonB -1.2 -2.5 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b1686 ydiI -1.2 -1.5 hypothetical protein (NCBI) compare
b3961 oxyR -1.1 -6.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1728 ydjM -1.1 -2.5 predicted inner membrane protein regulated by LexA (RefSeq) compare
b2846 yqeH -1.1 -2.5 orf, hypothetical protein (VIMSS) compare
b4546 ypeB -1.1 -1.3 hypothetical protein (NCBI) compare
b1576 ydfD -1.1 -2.1 Qin prophage; predicted protein (NCBI) compare
b1058 yceO -1.1 -1.1 hypothetical protein (NCBI) compare
b3442 yhhZ -1.1 -2.1 hypothetical protein (NCBI) compare
b4480 hdfR -1.1 -3.3 transcriptional regulator HdfR (NCBI) compare
b2424 cysU -1.1 -2.0 sulfate/thiosulfate transporter subunit (NCBI) compare
b3871 bipA -1.1 -6.3 GTP-binding protein (NCBI) compare
b3863 polA -1.1 -0.7 DNA polymerase I (NCBI) compare
b1548 nohA -1.1 -1.7 Qin prophage; predicted packaging protein (RefSeq) compare
b2822 recC -1.1 -2.8 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2894 xerD -1.1 -1.3 site-specific tyrosine recombinase XerD (NCBI) compare
b3977 tyrU -1.1 -1.4 tRNA-Tyr (NCBI) compare
b3261 fis -1.1 -1.4 DNA-binding protein Fis (NCBI) compare
b2479 gcvR -1.1 -2.4 transcriptional regulation of gcv operon (VIMSS) compare
b2679 proX -1.1 -2.6 glycine betaine transporter subunit (NCBI) compare
b1332 ynaJ -1.1 -1.4 predicted inner membrane protein (NCBI) compare
b3027 ygiZ -1.0 -2.3 conserved inner membrane protein (NCBI) compare
b1712 ihfA -1.0 -1.8 integration host factor subunit alpha (NCBI) compare
b0890 ftsK -1.0 -4.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2683 ygaH -1.0 -3.5 predicted inner membrane protein (NCBI) compare
b0880 cspD -1.0 -1.7 cold shock protein homolog (NCBI) compare
b1708 nlpC -1.0 -3.0 predicted lipoprotein (NCBI) compare
b2937 speB -1.0 -3.8 agmatinase (NCBI) compare
b3163 nlpI -1.0 -2.7 hypothetical protein (NCBI) compare
b2426 ucpA -1.0 -1.7 putative oxidoreductase (VIMSS) compare
b3609 secB -1.0 -2.3 export protein SecB (NCBI) compare
b1628 rsxB -0.9 -1.7 electron transport complex protein RnfB (NCBI) compare
b0189 yaeO -0.9 -2.8 orf, hypothetical protein (VIMSS) compare
b0471 ybaB -0.9 -2.1 hypothetical protein (NCBI) compare
b4590 ybfK -0.9 -3.4 hypothetical protein (RefSeq) compare
b2938 speA -0.9 -5.4 arginine decarboxylase (NCBI) compare
b1551 b1551 -0.9 -1.8 orf, hypothetical protein (VIMSS) compare
b4402 yjjY -0.9 -1.3 hypothetical protein (NCBI) compare
b3962 udhA -0.9 -5.0 putative oxidoreductase (VIMSS) compare
b1324 tpx -0.9 -2.2 thiol peroxidase (NCBI) compare
b1138 ymfE -0.9 -1.0 e14 prophage; predicted inner membrane protein (NCBI) compare
b1187 fadR -0.9 -2.6 fatty acid metabolism regulator (NCBI) compare
b1830 prc -0.9 -3.3 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b2553 glnB -0.9 -2.8 regulatory protein P-II for glutamine synthetase (NCBI) compare
b0456 ybaA -0.9 -2.3 hypothetical protein (NCBI) compare
b1183 umuD -0.9 -1.4 DNA polymerase V, subunit D (NCBI) compare
b0763 modA -0.9 -2.5 molybdate transporter subunit (NCBI) compare
b1222 narX -0.9 -2.2 sensory histidine kinase in two-component regulatory system with NarL (NCBI) compare
b4178 yjeB -0.9 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b3361 fic -0.9 -2.7 stationary-phase protein, cell division (NCBI) compare
b4139 aspA -0.9 -4.7 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2330 yfcB -0.9 -1.2 putative adenine-specific methylase (VIMSS) compare
b3644 yicC -0.9 -2.9 hypothetical protein (NCBI) compare
b4416 rybA -0.9 -1.4 unknown RNA (NCBI) compare
b4208 cycA -0.9 -4.3 D-alanine/D-serine/glycine transporter (NCBI) compare
b3726 pstA -0.8 -3.2 phosphate transporter subunit (NCBI) compare
b1524 yneH -0.8 -1.0 predicted glutaminase (NCBI) compare
b2567 rnc -0.8 -0.8 ribonuclease III (NCBI) compare
b3229 sspA -0.8 -2.0 stringent starvation protein A (NCBI) compare
b0049 apaH -0.8 -2.9 diadenosinetetraphosphatase (NCBI) compare
b2283 nuoG -0.8 -3.6 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3613 yibP -0.8 -2.9 putative membrane protein (VIMSS) compare
b2343 b2343 -0.8 -1.1 orf, hypothetical protein (VIMSS) compare
b1427 rimL -0.8 -1.5 ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) compare
b2699 recA -0.8 -0.5 recombinase A (NCBI) compare
b1860 ruvB -0.8 -1.0 Holliday junction DNA helicase B (NCBI) compare
b2743 pcm -0.8 -1.8 protein-L-isoaspartate O-methyltransferase (NCBI) compare
b1366 ydaY -0.8 -2.5 Rac prophage; predicted protein (RefSeq) compare
b1085 b1085 -0.8 -1.1 orf, hypothetical protein (VIMSS) compare
b4631 ykgQ -0.8 -1.4 no description compare
b3728 pstS -0.8 -2.3 phosphate transporter subunit (NCBI) compare
b0603 ybdO -0.8 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b4529 ydbJ -0.8 -0.9 hypothetical protein (NCBI) compare
b1295 ymjA -0.8 -1.4 hypothetical protein (NCBI) compare
b4647 mokA -0.8 -1.3 no description compare
b2666 yqaE -0.8 -2.0 predicted membrane protein (NCBI) compare
b1936 intG -0.8 -1.5 predicted defective phage integrase (pseudogene) (RefSeq) compare
b1607 ydgC -0.8 -1.4 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b2939 yqgB -0.8 -1.0 predicted protein (RefSeq) compare
b2279 nuoK -0.8 -1.4 NADH dehydrogenase subunit K (NCBI) compare
b2642 yfjW -0.8 -1.4 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1658 purR -0.8 -2.7 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b4375 prfC -0.8 -3.4 peptide chain release factor 3 (NCBI) compare
b1806 yeaY -0.8 -2.2 predicted lipoprotein (NCBI) compare
b1286 rnb -0.8 -1.6 exoribonuclease II (NCBI) compare
b1562 hokD -0.8 -1.2 Qin prophage; small toxic polypeptide (NCBI) compare
b1095 fabF -0.8 -3.2 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3811 xerC -0.8 -1.8 site-specific tyrosine recombinase XerC (NCBI) compare
b1040 csgD -0.8 -2.8 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b0036 caiD -0.7 -3.6 crotonobetainyl CoA hydratase (RefSeq) compare
b1160 elbA -0.7 -1.6 hypothetical protein (NCBI) compare
b0623 cspE -0.7 -1.3 cold shock protein E (NCBI) compare
b3792 wzxE -0.7 -3.9 O-antigen translocase (NCBI) compare
b0051 ksgA -0.7 -2.5 dimethyladenosine transferase (NCBI) compare
b1954 dsrA -0.7 -1.3 regulatory antisense RNA (NCBI) compare
b1582 ynfA -0.7 -1.7 hypothetical protein (NCBI) compare
b1742 b1742 -0.7 -1.2 orf, hypothetical protein (VIMSS) compare
b0957 ompA -0.7 -2.2 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2277 nuoM -0.7 -2.6 NADH dehydrogenase subunit M (NCBI) compare
b0802 ybiJ -0.7 -1.4 hypothetical protein (NCBI) compare
b0764 modB -0.7 -2.2 molybdate ABC transporter permease protein (NCBI) compare
b1817 manX -0.7 -2.9 fused mannose-specific PTS enzymes: IIA component/IIB component (NCBI) compare
b3390 aroK -0.7 -1.1 shikimate kinase I (NCBI) compare
b1961 dcm -0.7 -1.1 DNA cytosine methylase (NCBI) compare
b0357 yaiN -0.7 -1.0 putative alpha helix chain (VIMSS) compare
b2517 yfgB -0.7 -2.8 predicted enzyme (NCBI) compare
b1273 yciN -0.7 -0.7 hypothetical protein (NCBI) compare
b1001 yccE -0.7 -1.5 hypothetical protein (NCBI) compare
b2049 cpsB -0.7 -2.1 mannose-1-phosphate guanyltransferase (NCBI) compare
b2820 recB -0.7 -0.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3742 mioC -0.7 -2.2 flavodoxin (NCBI) compare
b4697 yrdF -0.7 -1.3 no description compare
b2278 nuoL -0.7 -3.5 NADH dehydrogenase subunit L (NCBI) compare
b4255 yjgD -0.7 -1.9 hypothetical protein (NCBI) compare
b2419 yfeK -0.7 -1.1 hypothetical protein (NCBI) compare
b1257 yciE -0.7 -1.4 hypothetical protein (NCBI) compare
b1175 minD -0.7 -2.4 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1724 ydiZ -0.7 -1.0 hypothetical protein (NCBI) compare
b2058 wcaB -0.7 -0.9 predicted acyl transferase (NCBI) compare
b1569 dicC -0.7 -1.4 Qin prophage; DNA-binding transcriptional regulator for DicB (NCBI) compare
b0226 dinJ -0.7 -1.6 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b2286 nuoC -0.7 -2.3 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b2512 yfgL -0.7 -2.0 protein assembly complex, lipoprotein component (NCBI) compare
b0949 uup -0.7 -3.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b3258 panF -0.7 -3.8 sodium/pantothenate symporter (VIMSS) compare
b0460 hha -0.7 -2.9 modulator of gene expression, with H-NS (NCBI) compare
b1729 ydjN -0.7 -1.8 predicted transporter (NCBI) compare
b3205 yhbJ -0.7 -1.7 hypothetical protein (NCBI) compare
b0615 citF -0.7 -1.9 citrate lyase, citrate-ACP transferase (alpha) subunit (NCBI) compare
b2565 recO -0.7 -2.4 DNA repair protein RecO (NCBI) compare
b2392 mntH -0.6 -2.8 manganese transport protein MntH (NCBI) compare
b2617 smpA -0.6 -1.1 small membrane protein A (VIMSS) compare
b0119 yacL -0.6 -2.9 orf, hypothetical protein (VIMSS) compare
b1150 ymfR -0.6 -0.6 e14 prophage; predicted protein (NCBI) compare
b2947 gshB -0.6 -1.7 glutathione synthetase (NCBI) compare
b1959 yedA -0.6 -1.7 predicted inner membrane protein (NCBI) compare
b1448 yncA -0.6 -1.3 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b3257 yhdT -0.6 -1.2 conserved inner membrane protein (NCBI) compare
b3764 yifE -0.6 -1.9 hypothetical protein (NCBI) compare
b0630 lipB -0.6 -0.9 protein of lipoate biosynthesis (VIMSS) compare
b1739 osmE -0.6 -1.1 DNA-binding transcriptional activator (NCBI) compare
b0405 queA -0.6 -2.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (NCBI) compare
b4195 ulaC -0.6 -1.5 L-ascorbate-specific enzyme IIA component of PTS (NCBI) compare
b1394 paaG -0.6 -1.2 enoyl-CoA hydratase (NCBI) compare
b1289 ycjD -0.6 -1.4 hypothetical protein (NCBI) compare
b1684 sufA -0.6 -1.3 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b2977 glcG -0.6 -1.8 hypothetical protein (NCBI) compare
b1772 b1772 -0.6 -2.7 putative kinase (VIMSS) compare
b3512 GadE -0.6 -2.2 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b1253 yciA -0.6 -1.3 predicted hydrolase (NCBI) compare
b2288 nuoA -0.6 -1.2 NADH dehydrogenase I chain A (VIMSS) compare
b0149 mrcB -0.6 -3.9 penicillin-binding protein 1b (NCBI) compare
b4614 sokA -0.6 -2.0 no description compare
b1337 abgB -0.6 -1.4 predicted peptidase, aminobenzoyl-glutamate utilization protein (NCBI) compare
b1078 flgG -0.6 -2.6 flagellar component of cell-distal portion of basal-body rod (NCBI) compare
b1992 cobS -0.6 -1.3 cobalamin synthase (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For stress Sodium Chlorite in Escherichia coli BW25113

For stress Sodium Chlorite across organisms