Experiment set2IT014 for Escherichia coli BW25113

Compare to:

LB with Sodium nitrite 20 mM

200 most important genes:

  gene name fitness t score description  
b3792 wzxE -2.7 -6.7 O-antigen translocase (NCBI) compare
b0049 apaH -2.6 -5.3 diadenosinetetraphosphatase (NCBI) compare
b0683 fur -2.5 -2.2 ferric uptake regulator (NCBI) compare
b2279 nuoK -2.3 -2.8 NADH dehydrogenase subunit K (NCBI) compare
b0726 sucA -2.1 -3.2 alpha-ketoglutarate decarboxylase (NCBI) compare
b3977 tyrU -2.0 -2.1 tRNA-Tyr (NCBI) compare
b0737 tolQ -1.9 -3.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0500 ybbD -1.8 -2.2 hypothetical protein (RefSeq) compare
b4375 prfC -1.8 -4.9 peptide chain release factor 3 (NCBI) compare
b2330 yfcB -1.7 -2.1 putative adenine-specific methylase (VIMSS) compare
b3725 pstB -1.7 -1.6 phosphate transporter subunit (NCBI) compare
b0603 ybdO -1.7 -3.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b3341 rpsG -1.7 -1.8 30S ribosomal protein S7 (NCBI) compare
b2055 wcaE -1.7 -3.8 predicted glycosyl transferase (NCBI) compare
b3617 kbl -1.6 -5.9 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b2281 nuoI -1.6 -2.3 NADH dehydrogenase subunit I (NCBI) compare
b0226 dinJ -1.6 -2.7 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b2110 yehC -1.6 -3.4 predicted periplasmic pilin chaperone (NCBI) compare
b0728 sucC -1.5 -4.9 succinyl-CoA synthetase subunit beta (NCBI) compare
b4172 hfq -1.5 -1.8 RNA-binding protein Hfq (NCBI) compare
b0118 acnB -1.5 -2.3 aconitate hydratase (NCBI) compare
b3649 rpoZ -1.4 -2.6 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3493 pitA -1.4 -5.6 phosphate transporter, low-affinity (NCBI) compare
b0200 gmhB -1.4 -1.5 hypothetical protein (NCBI) compare
b1576 ydfD -1.4 -2.3 Qin prophage; predicted protein (NCBI) compare
b1290 sapF -1.4 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0738 tolR -1.4 -2.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1347 ydaC -1.3 -2.3 Rac prophage; predicted protein (NCBI) compare
b3811 xerC -1.3 -2.5 site-specific tyrosine recombinase XerC (NCBI) compare
b4647 mokA -1.3 -2.0 no description compare
b0724 sdhB -1.3 -4.0 succinate dehydrogenase, FeS subunit (NCBI) compare
b3229 sspA -1.3 -2.9 stringent starvation protein A (NCBI) compare
b4402 yjjY -1.3 -1.5 hypothetical protein (NCBI) compare
b3741 gidA -1.3 -5.0 glucose-inhibited division protein A (NCBI) compare
b1103 ycfF -1.3 -1.6 orf, hypothetical protein (VIMSS) compare
b0630 lipB -1.3 -1.6 protein of lipoate biosynthesis (VIMSS) compare
b3962 udhA -1.3 -6.2 putative oxidoreductase (VIMSS) compare
b4443 gcvB -1.2 -1.2 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b1863 ruvC -1.2 -2.6 Holliday junction resolvase (NCBI) compare
b3169 nusA -1.2 -2.5 transcription elongation factor NusA (NCBI) compare
b0740 tolB -1.2 -3.5 translocation protein TolB precursor (NCBI) compare
b1728 ydjM -1.2 -2.5 predicted inner membrane protein regulated by LexA (RefSeq) compare
b1497 b1497 -1.2 -3.1 putative enzyme (VIMSS) compare
b0880 cspD -1.1 -1.7 cold shock protein homolog (NCBI) compare
b3257 yhdT -1.1 -2.3 conserved inner membrane protein (NCBI) compare
b2276 nuoN -1.1 -3.3 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3121 yhaC -1.1 -1.8 hypothetical protein (NCBI) compare
b1258 yciF -1.1 -2.2 hypothetical protein (NCBI) compare
b2809 b2809 -1.1 -2.0 orf, hypothetical protein (VIMSS) compare
b1860 ruvB -1.1 -1.2 Holliday junction DNA helicase B (NCBI) compare
b2286 nuoC -1.1 -3.2 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1961 dcm -1.0 -1.5 DNA cytosine methylase (NCBI) compare
b3935 priA -1.0 -1.8 primosome assembly protein PriA (NCBI) compare
b2278 nuoL -1.0 -5.1 NADH dehydrogenase subunit L (NCBI) compare
b1837 yebW -1.0 -1.6 orf, hypothetical protein (VIMSS) compare
b2287 nuoB -1.0 -2.2 NADH dehydrogenase subunit B (NCBI) compare
b1936 intG -1.0 -1.8 predicted defective phage integrase (pseudogene) (RefSeq) compare
b4570 lomR -1.0 -2.1 no description compare
b1658 purR -1.0 -3.3 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b2277 nuoM -1.0 -3.1 NADH dehydrogenase subunit M (NCBI) compare
b3390 aroK -1.0 -1.4 shikimate kinase I (NCBI) compare
b3706 trmE -1.0 -4.0 tRNA modification GTPase (NCBI) compare
b3162 deaD -1.0 -2.8 inducible ATP-independent RNA helicase (VIMSS) compare
b3164 pnp -1.0 -1.8 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1607 ydgC -1.0 -1.6 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b0437 clpP -1.0 -4.2 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b4146 yjeK -1.0 -2.3 predicted lysine aminomutase (NCBI) compare
b4201 priB -1.0 -1.9 primosomal replication protein N (NCBI) compare
b2283 nuoG -1.0 -3.9 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b1278 pgpB -1.0 -1.5 phosphatidylglycerophosphatase B (NCBI) compare
b2620 smpB -0.9 -1.2 SsrA-binding protein (NCBI) compare
b3791 rffA -0.9 -4.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b2625 yfjI -0.9 -3.6 CP4-57 prophage; predicted protein (NCBI) compare
b1727 yniC -0.9 -2.0 predicted hydrolase (NCBI) compare
b4548 ypjJ -0.9 -1.9 hypothetical protein (NCBI) compare
b0739 tolA -0.9 -2.1 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2953 yggU -0.9 -1.1 orf, hypothetical protein (VIMSS) compare
b3616 tdh -0.9 -2.8 L-threonine 3-dehydrogenase (NCBI) compare
b1332 ynaJ -0.9 -1.0 predicted inner membrane protein (NCBI) compare
b0303 ykgI -0.9 -2.4 orf, hypothetical protein (VIMSS) compare
b0890 ftsK -0.9 -3.5 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0113 pdhR -0.9 -2.6 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b0051 ksgA -0.9 -2.7 dimethyladenosine transferase (NCBI) compare
b2280 nuoJ -0.9 -2.6 NADH dehydrogenase subunit J (NCBI) compare
b0849 grxA -0.9 -1.6 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) (NCBI) compare
b4063 soxR -0.9 -2.7 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing (NCBI) compare
b0792 ybhR -0.9 -2.6 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b4578 insP -0.9 -1.3 no description compare
b1827 kdgR -0.9 -1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0723 sdhA -0.9 -4.3 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b1257 yciE -0.9 -1.9 hypothetical protein (NCBI) compare
b2642 yfjW -0.9 -1.2 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3728 pstS -0.9 -2.6 phosphate transporter subunit (NCBI) compare
b1252 tonB -0.9 -1.8 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b4416 rybA -0.8 -1.4 unknown RNA (NCBI) compare
b2259 pmrD -0.8 -1.0 polymyxin resistance protein B (VIMSS) compare
b1167 ymgC -0.8 -1.1 hypothetical protein (NCBI) compare
b4177 purA -0.8 -1.8 adenylosuccinate synthetase (NCBI) compare
b4493 gapC -0.8 -1.4 no description compare
b0237 pepD -0.8 -3.7 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b3082 ygjM -0.8 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3609 secB -0.8 -2.5 export protein SecB (NCBI) compare
b4631 ykgQ -0.8 -1.4 no description compare
b3398 yrfF -0.8 -1.6 predicted inner membrane protein (NCBI) compare
b1040 csgD -0.8 -2.8 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b4294 insA-7 -0.8 -1.3 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b4590 ybfK -0.8 -2.8 hypothetical protein (RefSeq) compare
b1861 ruvA -0.8 -1.2 Holliday junction DNA helicase motor protein (NCBI) compare
b0430 cyoC -0.8 -2.1 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b1526 yneJ -0.8 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b4163 glyV -0.8 -0.9 tRNA-Gly (NCBI) compare
b3086 ygjQ -0.8 -2.5 predicted thioredoxin-like (NCBI) compare
b3443 yrhA -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b0957 ompA -0.8 -2.2 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2168 fruK -0.8 -1.3 1-phosphofructokinase (NCBI) compare
b1213 ychQ -0.7 -1.9 predicted transcriptional regulator (NCBI) compare
b0641 rlpB -0.7 -1.4 minor lipoprotein (NCBI) compare
b3844 fre -0.7 -2.5 NAD(P)H-flavin reductase (NCBI) compare
b3871 bipA -0.7 -4.5 GTP-binding protein (NCBI) compare
b1540 ydfH -0.7 -0.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b1263 trpD -0.7 -1.3 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b4179 vacB -0.7 -3.3 putative enzyme (VIMSS) compare
b4503 yafF -0.7 -1.2 no description compare
b1235 rssB -0.7 -3.2 response regulator of RpoS (NCBI) compare
b1685 ydiH -0.7 -1.1 predicted protein (RefSeq) compare
b0560 nohB -0.7 -1.3 DLP12 prophage; DNA packaging protein (NCBI) compare
b0088 murD -0.7 -1.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1742 b1742 -0.7 -1.3 orf, hypothetical protein (VIMSS) compare
b0431 cyoB -0.7 -3.8 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b2790 yqcA -0.7 -1.9 flavodoxin (NCBI) compare
b1589 ynfG -0.7 -1.7 oxidoreductase, Fe-S subunit (NCBI) compare
b2352 yfdI -0.7 -1.8 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b0872 hcr -0.7 -1.0 HCP oxidoreductase, NADH-dependent (NCBI) compare
b1920 fliY -0.7 -1.0 cystine transporter subunit (NCBI) compare
b3094 exuR -0.7 -2.4 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b4595 yciY -0.7 -0.9 hypothetical protein (RefSeq) compare
b0092 ddlB -0.7 -2.1 D-alanylalanine synthetase (NCBI) compare
b1409 ynbB -0.7 -2.8 predicted CDP-diglyceride synthase (NCBI) compare
b2049 cpsB -0.7 -1.8 mannose-1-phosphate guanyltransferase (NCBI) compare
b4178 yjeB -0.7 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b3426 glpD -0.7 -2.8 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1644 b1644 -0.7 -1.6 putative membrane protein (VIMSS) compare
b1765 ydjA -0.7 -0.6 predicted oxidoreductase (NCBI) compare
b3866 yihI -0.7 -2.6 hypothetical protein (NCBI) compare
b0428 cyoE -0.7 -2.7 protoheme IX farnesyltransferase (NCBI) compare
b4651 yibW -0.7 -1.0 no description compare
b1551 b1551 -0.7 -1.1 orf, hypothetical protein (VIMSS) compare
b0232 yafN -0.7 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b2991 hybF -0.7 -2.2 protein involved with the maturation of hydrogenases 1 and 2 (NCBI) compare
b2576 srmB -0.7 -1.5 ATP-dependent RNA helicase (NCBI) compare
b0014 dnaK -0.7 -0.7 molecular chaperone DnaK (NCBI) compare
b2846 yqeH -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b4571 wbbL -0.6 -1.7 no description compare
b3650 spoT -0.6 -2.8 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b2531 iscR -0.6 -0.8 DNA-binding transcriptional repressor (NCBI) compare
b3237 argR -0.6 -1.9 arginine repressor (NCBI) compare
b4100 phnH -0.6 -1.6 carbon-phosphorus lyase complex subunit (NCBI) compare
b1612 fumA -0.6 -1.7 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b0080 fruR -0.6 -2.3 DNA-binding transcriptional dual regulator (NCBI) compare
b2782 chpA -0.6 -1.8 toxin of the ChpA-ChpR toxin-antitoxin system, endoribonuclease (NCBI) compare
b3033 yqiB -0.6 -2.1 predicted dehydrogenase (NCBI) compare
b1944 fliL -0.6 -1.9 flagellar basal body-associated protein FliL (NCBI) compare
b4139 aspA -0.6 -3.4 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b0438 clpX -0.6 -2.8 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1738 chbB -0.6 -2.4 N,N'-diacetylchitobiose-specific enzyme IIB component of PTS (NCBI) compare
b4128 yjdK -0.6 -2.2 hypothetical protein (NCBI) compare
b1346 ydaQ -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b1153 ymfQ -0.6 -2.0 e14 prophage; conserved protein (NCBI) compare
b2567 rnc -0.6 -0.7 ribonuclease III (NCBI) compare
b2565 recO -0.6 -2.3 DNA repair protein RecO (NCBI) compare
b1084 rne -0.6 -1.9 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b1126 potA -0.6 -2.5 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b2553 glnB -0.6 -2.0 regulatory protein P-II for glutamine synthetase (NCBI) compare
b3438 gntR -0.6 -2.6 DNA-binding transcriptional repressor (NCBI) compare
b0365 tauA -0.6 -2.0 taurine transport system periplasmic protein (VIMSS) compare
b3836 b3836 -0.6 -1.7 orf, hypothetical protein (VIMSS) compare
b0218 yafU -0.6 -1.8 predicted inner membrane protein (RefSeq) compare
b3131 agaR -0.6 -1.7 DNA-binding transcriptional dual regulator (NCBI) compare
b2318 truA -0.6 -1.4 tRNA pseudouridine synthase A (NCBI) compare
b3029 ygiN -0.6 -1.0 quinol monooxygenase (NCBI) compare
b4462 ygaQ -0.6 -3.0 hypothetical protein (RefSeq) compare
b2699 recA -0.6 -0.6 recombinase A (NCBI) compare
b1380 ldhA -0.6 -1.0 D-lactate dehydrogenase (NCBI) compare
b0436 tig -0.6 -2.9 trigger factor (NCBI) compare
b3806 cyaA -0.6 -2.0 adenylate cyclase (NCBI) compare
b2966 yqgA -0.6 -2.0 predicted inner membrane protein (NCBI) compare
b1379 hslJ -0.6 -1.6 heat-inducible protein (NCBI) compare
b1423 ydcJ -0.6 -1.5 hypothetical protein (NCBI) compare
b1029 ycdU -0.6 -3.3 predicted inner membrane protein (NCBI) compare
b0862 artQ -0.6 -1.4 arginine transporter subunit (NCBI) compare
b2181 yejG -0.6 -2.1 hypothetical protein (NCBI) compare
b4253 yjgL -0.6 -2.4 orf, hypothetical protein (VIMSS) compare
b3723 bglG -0.6 -3.8 transcriptional antiterminator of the bgl operon (NCBI) compare
b2586 yfiM -0.6 -1.5 predicted protein (RefSeq) compare
b4454 rdlD -0.6 -1.7 sRNA antisense regulator affects LdrD translation; proposed addiction module in LDR-D repeat, with toxic peptide LdrD (RefSeq) compare
b1434 ydcN -0.6 -0.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b1337 abgB -0.6 -1.3 predicted peptidase, aminobenzoyl-glutamate utilization protein (NCBI) compare
b2897 ygfY -0.6 -1.0 hypothetical protein (NCBI) compare
b1984 asnW -0.6 -0.7 tRNA-Asn (NCBI) compare
b1688 ydiK -0.6 -2.1 predicted inner membrane protein (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Sodium nitrite in Escherichia coli BW25113

For stress Sodium nitrite across organisms