Experiment set2IT009 for Pseudomonas sp. RS175

Compare to:

trans-aconitic acid carbon source 5 mM

200 most important genes:

  gene name fitness t score description  
PFR28_03860 -5.5 -7.5 putative murein peptide carboxypeptidase compare
PFR28_02823 -5.4 -3.7 3-isopropylmalate dehydratase small subunit 1 compare
PFR28_02824 -5.4 -9.0 3-isopropylmalate dehydratase large subunit compare
PFR28_00186 -5.2 -7.9 ATP phosphoribosyltransferase compare
PFR28_05015 -4.9 -28.4 Glutamate synthase [NADPH] large chain compare
PFR28_03697 -4.9 -18.0 Ketol-acid reductoisomerase (NADP(+)) compare
PFR28_02821 -4.8 -22.1 3-isopropylmalate dehydrogenase compare
PFR28_03363 -4.7 -19.5 Ornithine carbamoyltransferase 1, anabolic compare
PFR28_05105 -4.7 -12.8 Phosphoserine phosphatase SerB2 compare
PFR28_05016 -4.7 -18.3 Glutamate synthase [NADPH] small chain compare
PFR28_04202 -4.6 -4.5 5,10-methylenetetrahydrofolate reductase compare
PFR28_02810 -4.5 -18.9 O-succinylhomoserine sulfhydrylase compare
PFR28_04278 -4.4 -15.4 Dihydroxy-acid dehydratase compare
PFR28_04832 -4.4 -14.9 putative phosphatase compare
PFR28_04308 -4.4 -3.0 Amino-acid acetyltransferase compare
PFR28_04929 -4.4 -7.9 Histidine biosynthesis bifunctional protein HisB compare
PFR28_03699 -4.4 -8.4 Acetolactate synthase isozyme 3 large subunit compare
PFR28_04245 -4.4 -17.7 Homoserine O-succinyltransferase compare
PFR28_01365 -4.4 -8.8 hypothetical protein compare
PFR28_02925 -4.3 -15.0 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) compare
PFR28_04933 -4.3 -4.8 Imidazole glycerol phosphate synthase subunit HisF compare
PFR28_05125 -4.1 -10.9 ATP phosphoribosyltransferase regulatory subunit compare
PFR28_04834 -4.0 -19.0 L-threonine dehydratase biosynthetic IlvA compare
PFR28_04930 -4.0 -12.4 Imidazole glycerol phosphate synthase subunit HisH compare
PFR28_02811 -3.9 -8.7 Amidophosphoribosyltransferase compare
PFR28_02603 -3.8 -9.8 Siroheme synthase compare
PFR28_04932 -3.8 -8.0 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PFR28_03217 -3.7 -2.6 Phosphoribosylformylglycinamidine cyclo-ligase compare
PFR28_01366 -3.7 -11.7 Sulfite reductase [ferredoxin] compare
PFR28_00187 -3.7 -13.2 Histidinol dehydrogenase compare
PFR28_00305 -3.6 -9.5 2-isopropylmalate synthase compare
PFR28_04246 -3.6 -10.7 Bifunctional methionine biosynthesis protein MetXA/MetW compare
PFR28_02616 -3.6 -20.2 Isocitrate dehydrogenase [NADP] compare
PFR28_02608 -3.5 -4.1 DNA translocase FtsK compare
PFR28_03698 -3.5 -11.8 Acetolactate synthase isozyme 3 small subunit compare
PFR28_03718 -3.5 -5.7 Transcriptional regulatory protein ZraR compare
PFR28_04985 -3.4 -7.6 Phosphoribosyl-ATP pyrophosphatase compare
PFR28_01943 -3.4 -5.6 Putative isomerase YbhH conserved
PFR28_04842 -3.4 -6.9 D-3-phosphoglycerate dehydrogenase compare
PFR28_03012 -3.3 -10.4 Phosphate acyltransferase compare
PFR28_01942 -3.3 -10.5 HTH-type transcriptional regulator CynR conserved
PFR28_00188 -3.2 -11.3 Histidinol-phosphate aminotransferase compare
PFR28_05244 -3.2 -16.1 Copper-exporting P-type ATPase compare
PFR28_03223 -3.2 -14.1 GTP pyrophosphokinase compare
PFR28_04986 -3.2 -8.0 Phosphoribosyl-AMP cyclohydrolase compare
PFR28_03714 -3.1 -15.6 RNA polymerase-binding transcription factor DksA compare
PFR28_01944 -3.1 -12.7 Citrate transporter compare
PFR28_04103 -3.0 -11.5 Biotin synthase compare
PFR28_01930 -3.0 -5.6 HTH-type transcriptional regulator McbR compare
PFR28_03218 -3.0 -10.2 Phosphoribosylglycinamide formyltransferase compare
PFR28_04565 -2.9 -14.0 Protein RarD compare
PFR28_04436 -2.8 -10.0 hypothetical protein compare
PFR28_03282 -2.8 -12.0 Arginine N-succinyltransferase subunit alpha compare
PFR28_00193 -2.6 -12.8 Sulfate adenylyltransferase subunit 2 compare
PFR28_00194 -2.5 -11.4 Bifunctional enzyme CysN/CysC compare
PFR28_03635 -2.5 -7.3 Malate:quinone oxidoreductase compare
PFR28_00966 -2.2 -15.2 HTH-type transcriptional regulator CysB compare
PFR28_03388 -2.2 -11.5 Quinolinate synthase A compare
PFR28_01230 -2.1 -6.5 Lon protease compare
PFR28_01113 -2.0 -5.3 DNA topoisomerase 1 compare
PFR28_05212 -2.0 -11.8 Sensor histidine kinase RcsC compare
PFR28_01114 -2.0 -8.1 hypothetical protein compare
PFR28_00098 -2.0 -8.4 Nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
PFR28_01156 -2.0 -7.0 hypothetical protein compare
PFR28_03721 -1.9 -6.2 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PFR28_02924 -1.9 -3.4 2-methyl-aconitate isomerase compare
PFR28_04958 -1.8 -2.5 hypothetical protein compare
PFR28_02838 -1.8 -10.2 Aromatic-amino-acid aminotransferase compare
PFR28_01809 -1.8 -1.4 hypothetical protein compare
PFR28_04100 -1.8 -8.2 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PFR28_01040 -1.7 -8.0 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase compare
PFR28_04874 -1.7 -9.3 Phosphoenolpyruvate carboxykinase (ATP) compare
PFR28_04102 -1.7 -8.8 8-amino-7-oxononanoate synthase compare
PFR28_02704 -1.6 -1.3 hypothetical protein compare
PFR28_04865 -1.6 -7.5 Glutamate--cysteine ligase compare
PFR28_04072 -1.6 -4.1 Bifunctional folate synthesis protein compare
PFR28_04566 -1.5 -8.9 4-chloro-allylglycine synthase compare
PFR28_03130 -1.5 -3.3 Streptothricin hydrolase compare
PFR28_04208 -1.5 -5.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PFR28_04425 -1.5 -7.9 2-iminobutanoate/2-iminopropanoate deaminase compare
PFR28_01265 -1.5 -6.4 (R)-benzylsuccinyl-CoA dehydrogenase compare
PFR28_00839 -1.5 -5.6 hypothetical protein compare
PFR28_01312 -1.5 -3.7 HTH-type transcriptional regulator NorG compare
PFR28_02094 -1.5 -1.6 Glycerol-3-phosphate regulon repressor compare
PFR28_00425 -1.4 -9.9 Protein-L-isoaspartate O-methyltransferase compare
PFR28_00988 -1.4 -8.2 Sensor histidine kinase RcsC compare
PFR28_04564 -1.4 -9.5 Aspartate-semialdehyde dehydrogenase compare
PFR28_02009 -1.4 -1.7 HTH-type transcriptional regulator PgrR compare
PFR28_03420 -1.4 -4.0 hypothetical protein compare
PFR28_03612 -1.3 -4.3 Cell division protein ZapE compare
PFR28_04377 -1.3 -5.6 hypothetical protein compare
PFR28_00837 -1.3 -6.9 hypothetical protein compare
PFR28_04824 -1.3 -8.0 Cadmium-transporting ATPase compare
PFR28_02928 -1.3 -7.1 2-methylisocitrate lyase compare
PFR28_00212 -1.3 -5.5 hypothetical protein compare
PFR28_01330 -1.3 -1.5 Glucose starvation-inducible protein B compare
PFR28_02268 -1.3 -2.5 hypothetical protein compare
PFR28_02507 -1.3 -2.3 Phosphoglycolate phosphatase compare
PFR28_01118 -1.3 -2.9 hypothetical protein compare
PFR28_02478 -1.2 -2.8 hypothetical protein compare
PFR28_04585 -1.2 -4.9 Chromosome partitioning protein ParA compare
PFR28_05139 -1.2 -2.2 hypothetical protein compare
PFR28_01127 -1.2 -7.3 Soluble pyridine nucleotide transhydrogenase compare
PFR28_00356 -1.2 -3.6 Protein-glutamate methylesterase/protein-glutamine glutaminase compare
PFR28_01060 -1.2 -5.6 HTH-type transcriptional repressor NanR compare
PFR28_03413 -1.2 -3.6 Holliday junction ATP-dependent DNA helicase RuvA compare
PFR28_00873 -1.2 -5.2 hypothetical protein compare
PFR28_03951 -1.2 -1.3 hypothetical protein compare
PFR28_04110 -1.1 -8.3 Malate synthase G compare
PFR28_01154 -1.1 -1.7 hypothetical protein compare
PFR28_01084 -1.1 -5.0 hypothetical protein compare
PFR28_03427 -1.1 -4.6 Sensor histidine kinase RcsC compare
PFR28_04712 -1.1 -1.1 Dodecin compare
PFR28_00688 -1.1 -1.8 hypothetical protein compare
PFR28_03169 -1.1 -7.1 Tail-specific protease compare
PFR28_01142 -1.1 -8.7 Transaldolase compare
PFR28_04120 -1.1 -1.0 hypothetical protein compare
PFR28_04782 -1.1 -8.1 hypothetical protein compare
PFR28_01003 -1.1 -3.0 hypothetical protein compare
PFR28_01816 -1.1 -4.0 hypothetical protein compare
PFR28_00941 -1.0 -1.4 Potassium-transporting ATPase KdpC subunit compare
PFR28_03304 -1.0 -1.2 hypothetical protein compare
PFR28_01676 -1.0 -7.2 Na(+)/H(+) antiporter NhaB compare
PFR28_00424 -1.0 -4.2 '5'-nucleotidase SurE' transl_table=11 compare
PFR28_03272 -1.0 -1.2 Translational regulator CsrA2 compare
PFR28_00926 -1.0 -1.5 hypothetical protein compare
PFR28_03414 -1.0 -2.4 Crossover junction endodeoxyribonuclease RuvC compare
PFR28_04344 -1.0 -3.0 Exopolyphosphatase compare
PFR28_00689 -1.0 -8.3 L-aspartate oxidase compare
PFR28_01313 -1.0 -2.7 hypothetical protein compare
PFR28_00918 -1.0 -4.9 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) compare
PFR28_03719 -1.0 -3.5 Poly(A) polymerase I compare
PFR28_00681 -0.9 -6.2 hypothetical protein compare
PFR28_03281 -0.9 -3.9 Arginine N-succinyltransferase subunit beta compare
PFR28_03739 -0.9 -1.8 hypothetical protein compare
PFR28_01081 -0.9 -3.9 hypothetical protein compare
PFR28_03209 -0.9 -3.1 Corrinoid adenosyltransferase compare
PFR28_04944 -0.9 -3.6 DNA-binding transcriptional regulator NtrC compare
PFR28_04584 -0.9 -2.4 putative chromosome-partitioning protein ParB compare
PFR28_01083 -0.9 -4.4 putative copper-importing P-type ATPase A compare
PFR28_03463 -0.9 -2.1 hypothetical protein compare
PFR28_00158 -0.9 -5.9 Ribonuclease G compare
PFR28_04567 -0.9 -5.9 hypothetical protein compare
PFR28_00472 -0.9 -2.3 Protein RecA compare
PFR28_04345 -0.9 -7.1 Polyphosphate kinase compare
PFR28_04945 -0.9 -3.2 Sensory histidine kinase/phosphatase NtrB compare
PFR28_01137 -0.9 -1.6 hypothetical protein compare
PFR28_04569 -0.9 -4.4 HTH-type transcriptional regulator CdhR compare
PFR28_03653 -0.9 -1.6 Molybdopterin-synthase adenylyltransferase compare
PFR28_00680 -0.9 -5.4 hypothetical protein compare
PFR28_00159 -0.9 -6.2 hypothetical protein compare
PFR28_03182 -0.9 -2.0 Recombination-associated protein RdgC compare
PFR28_02750 -0.9 -2.0 Multiple antibiotic resistance protein MarR compare
PFR28_02484 -0.9 -6.0 UTP--glucose-1-phosphate uridylyltransferase compare
PFR28_00572 -0.9 -5.0 HTH-type transcriptional regulator HexR compare
PFR28_00331 -0.9 -3.0 Tyrosine recombinase XerD compare
PFR28_01425 -0.9 -2.4 hypothetical protein compare
PFR28_01460 -0.8 -0.9 Glutamine transport ATP-binding protein GlnQ compare
PFR28_03596 -0.8 -2.0 Transcriptional regulator MraZ compare
PFR28_04647 -0.8 -6.3 hypothetical protein compare
PFR28_02613 -0.8 -5.9 ATP-dependent Clp protease ATP-binding subunit ClpA compare
PFR28_00241 -0.8 -2.7 Disulfide bond formation protein B compare
PFR28_04252 -0.8 -4.3 Thiazole synthase compare
PFR28_02449 -0.8 -4.9 putative branched-chain-amino-acid aminotransferase compare
PFR28_03203 -0.8 -3.5 Bifunctional adenosylcobalamin biosynthesis protein CobP compare
PFR28_03204 -0.8 -4.7 Cobyric acid synthase compare
PFR28_00679 -0.8 -5.3 hypothetical protein compare
PFR28_03578 -0.8 -1.3 Transcriptional activator protein CzcR compare
PFR28_01378 -0.8 -2.3 Magnesium-chelatase 38 kDa subunit compare
PFR28_03844 -0.8 -2.9 Thiamine-phosphate synthase compare
PFR28_03625 -0.8 -5.6 Metalloprotease LoiP compare
PFR28_05071 -0.7 -3.7 D-inositol-3-phosphate glycosyltransferase compare
PFR28_02344 -0.7 -3.9 Chaperone protein HscC compare
PFR28_04628 -0.7 -1.6 Thiol:disulfide interchange protein DsbA compare
PFR28_00473 -0.7 -1.7 Regulatory protein RecX compare
PFR28_00913 -0.7 -3.3 Integration host factor subunit beta compare
PFR28_02719 -0.7 -1.1 Integration host factor subunit alpha compare
PFR28_03412 -0.7 -2.7 Holliday junction ATP-dependent DNA helicase RuvB compare
PFR28_00684 -0.7 -5.8 Sensor protein QseC compare
PFR28_04232 -0.7 -3.3 Glutathione synthetase compare
PFR28_00683 -0.7 -2.9 Transcriptional regulatory protein tctD compare
PFR28_03843 -0.7 -3.7 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
PFR28_04618 -0.7 -1.9 High-affinity zinc uptake system membrane protein ZnuB compare
PFR28_01108 -0.7 -3.6 Universal stress protein A compare
PFR28_03205 -0.7 -3.6 Histidinol-phosphate aminotransferase compare
PFR28_04737 -0.7 -4.8 Protein YdgA compare
PFR28_03856 -0.7 -1.6 LPS-assembly lipoprotein LptE compare
PFR28_03837 -0.7 -4.0 Leucine-responsive regulatory protein compare
PFR28_03208 -0.7 -4.7 Cobyrinate a,c-diamide synthase compare
PFR28_01763 -0.7 -2.3 Transcriptional regulatory protein OmpR compare
PFR28_00277 -0.7 -1.8 Queuine tRNA-ribosyltransferase compare
PFR28_04347 -0.7 -4.9 hypothetical protein compare
PFR28_00694 -0.7 -3.5 Beta-barrel assembly-enhancing protease compare
PFR28_00271 -0.7 -2.8 hypothetical protein compare
PFR28_05097 -0.7 -2.0 hypothetical protein compare
PFR28_03430 -0.7 -3.7 Arginine biosynthesis bifunctional protein ArgJ compare
PFR28_03202 -0.7 -1.4 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PFR28_02751 -0.7 -5.0 Translocation and assembly module subunit TamB compare
PFR28_02345 -0.7 -4.4 hypothetical protein compare
PFR28_00139 -0.7 -4.2 HTH-type transcriptional regulator LutR compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source trans-aconitic acid in Pseudomonas sp. RS175

For carbon source trans-aconitic acid across organisms