Experiment set29IT069 for Pseudomonas putida KT2440

Compare to:

rac-3-Hydroxypentanoic Acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_5248 +1.9 1.9 putative hydrolase compare
PP_5486 +1.5 2.8 conserved protein of unknown function compare
PP_0274 +1.3 1.2 putative transcriptional regulator containing HTH domain compare
PP_1783 +1.2 1.7 dTDP-glucose pyrophosphorylase compare
PP_0630 +1.1 1.3 DNA gyrase inhibitor YacG compare
PP_4099 +1.0 8.8 two-componenent system BarA/UvrY - regulatory subunit compare
PP_3971 +1.0 2.1 conserved protein of unknown function compare
PP_1650 +0.9 8.0 Sensor protein GacS compare
PP_5393 +0.9 1.3 putative metal-binding chaperone compare
PP_4952 +0.9 1.9 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_0874 +0.9 1.6 conserved protein of unknown function compare
PP_4271 +0.9 0.8 conserved protein of unknown function compare
PP_2191 +0.8 2.9 putative Lipoprotein compare
PP_2441 +0.8 2.0 conserved protein of unknown function compare
PP_1536 +0.8 3.1 conserved protein of unknown function compare
PP_5324 +0.8 2.4 Response regulator compare
PP_3916 +0.8 3.4 conserved protein of unknown function compare
PP_4981 +0.8 1.1 polyisoprene-binding protein, acidic stress response factor compare
PP_5705 +0.8 1.4 protein of unknown function compare
PP_3726 +0.8 1.4 Enoyl-CoA hydratase/isomerase family protein compare
PP_2889 +0.8 2.6 putative Transmembrane regulator PrtR compare
PP_1623 +0.7 4.9 RNA polymerase, sigma S (sigma 38) factor compare
PP_3380 +0.7 2.2 2-ketogluconate utilization repressor compare
PP_0683 +0.7 1.7 conserved protein of unknown function compare
PP_4961 +0.7 1.0 putative Lipoprotein compare
PP_4406 +0.7 1.4 conserved protein of unknown function compare
PP_4373 +0.7 5.9 Transcriptional regulator FleQ compare
PP_1609 +0.7 1.6 conserved protein of unknown function compare
PP_5583 +0.7 0.7 conserved protein of unknown function compare
PP_3392 +0.7 1.3 conserved protein of unknown function compare
PP_1020 +0.7 1.2 putative glucose-6-phosphate 1-epimerase compare
PP_5422 +0.7 2.2 hypothetical protein compare
PP_4949 +0.6 2.1 putative peptidase, TldD/PmbA family compare
PP_0957 +0.6 1.3 D-arabinose 5-phosphate isomerase compare
PP_0150 +0.6 1.5 conserved exported protein of unknown function compare
PP_2773 +0.6 1.2 conserved protein of unknown function compare
PP_1855 +0.6 2.3 conserved exported protein of unknown function compare
PP_0177 +0.6 2.8 conserved protein of unknown function compare
PP_4682 +0.6 2.0 conserved protein of unknown function containing tetratricopeptide repeat domain compare
PP_1692 +0.6 1.4 conserved protein of unknown function compare
PP_2622 +0.6 1.6 conserved protein of unknown function compare
PP_4739 +0.6 1.9 conserved protein of unknown function compare
PP_5711 +0.6 2.2 protein of unknown function compare
PP_0628 +0.6 2.1 conserved protein of unknown function compare
PP_0574 +0.6 4.9 DNA-binding response regulator, LuxR family compare
PP_2247 +0.6 1.2 putative Endoribonuclease compare
PP_2103 +0.6 1.6 conserved protein of unknown function compare
PP_4050 +0.6 4.9 glycogen synthase compare
PP_1938 +0.6 1.4 conserved protein of unknown function compare
PP_0804 +0.6 3.4 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_0176 +0.6 4.2 putative efflux transporter compare
PP_1142 +0.6 0.6 conserved protein of unknown function compare
PP_2907 +0.6 1.6 DNA-binding response regulator compare
PP_2634 +0.6 2.5 putative Cellulose synthase compare
PP_4213 +0.6 1.4 putative dipeptidase compare
PP_4171 +0.6 4.6 conserved exported protein of unknown function compare
PP_2437 +0.5 3.3 putative Acyl-CoA dehydrogenase compare
PP_4355 +0.5 2.0 flagellar export apparatus subunit compare
PP_5456 +0.5 0.8 conserved protein of unknown function compare
PP_4593 +0.5 1.3 conserved protein of unknown function compare
PP_2716 +0.5 1.5 arsenate reductase compare
PP_1141 +0.5 3.8 branched-chain amino acids ABC transporter - periplasmic leucine binding subunit compare
PP_1364 +0.5 3.6 conserved exported protein of unknown function compare
PP_1415 +0.5 1.0 putative membrane associated enzyme subunit compare
PP_0905 +0.5 0.7 conserved exported protein of unknown function compare
PP_3808 +0.5 0.9 Antibiotic synthesis protein MbtH compare
PP_5706 +0.5 1.4 Sec translocation complex - SecG subunit compare
PP_0357 +0.5 2.3 ACT domain protein compare
PP_5561 +0.5 2.2 conserved protein of unknown function compare
PP_1113 +0.5 3.5 Pyridoxal-phosphate dependent enzyme family protein compare
PP_5453 +0.5 1.1 conserved protein of unknown function compare
PP_0191 +0.5 1.5 Transcriptional regulatory protein AlgQ compare
PP_2455 +0.5 2.8 ribose ABC transporter - ATP-binding subunit compare
PP_2718 +0.5 0.8 arsenic resistance transcriptional regulator compare
PP_1044 +0.5 1.6 Lipoprotein UxpA compare
PP_5232 +0.5 1.0 conserved protein of unknown function compare
PP_3058 +0.5 2.1 conserved protein of unknown function compare
PP_2972 +0.5 1.0 conserved protein of unknown function compare
PP_1822 +0.5 1.6 conserved protein of unknown function compare
PP_4847 +0.5 1.1 chaperone modulatory of CbpA co-chaperone protein compare
PP_3924 +0.5 1.5 conserved protein of unknown function compare
PP_3563 +0.5 1.8 conserved exported protein of unknown function compare
PP_2931 +0.5 2.1 conserved protein of unknown function compare
PP_3899 +0.5 0.8 conserved protein of unknown function, hicB family compare
PP_1138 +0.5 1.8 branched chain amino acid transporter - ATP binding subunit compare
PP_0497 +0.5 2.4 Transcriptional regulator, Cro/CI family compare
PP_4372 +0.5 1.7 Sensory box histidine kinase FleS compare
PP_1137 +0.5 2.6 high-affinity branched-chain amino acid transporter, ATP binding compare
PP_1748 +0.5 2.0 conserved protein of unknown function compare
PP_0312 +0.5 2.6 electron transfer flavoprotein, alpha subunit compare
PP_3341 +0.5 1.3 nickel-responsive regulator compare
PP_1300 +0.5 1.3 putative amino acid ABC transporter - ATP-binding subunit compare
PP_0656 +0.5 2.4 putative Amino acid ABC transporter, permease protein compare
PP_5525 +0.5 1.3 conserved exported protein of unknown function compare
PP_0022 +0.5 1.1 hypothetical protein compare
PP_1262 +0.5 3.1 LysR family transcriptional regulator compare
PP_4382 +0.5 3.4 Peptidoglycan hydrolase FlgJ compare
PP_1441 +0.5 1.7 tRNA (cmo5U34)-methyltransferase compare
PP_1041 +0.5 1.0 twin arginine protein export complex subunit compare
PP_4207 +0.5 1.4 conserved protein of unknown function compare
PP_5682 +0.5 2.1 conserved protein of unknown function compare
PP_4369 +0.4 2.9 Flagellar M-ring protein compare
PP_2567 +0.4 3.0 Hydrolase, alpha/beta fold family compare
PP_3006 +0.4 2.5 RNA polymerase sigma-70 factor, ECF subfamily compare
PP_5701 +0.4 0.5 conserved protein of unknown function compare
PP_1392 +0.4 2.5 putative NAD-binding protein compare
PP_4558 +0.4 2.4 Acetyltransferase, GNAT family compare
PP_2067 +0.4 1.7 putative EmrB/QacA family drug resistance transporter compare
PP_5582 +0.4 0.6 conserved protein of unknown function compare
PP_1139 +0.4 3.5 branched chain amino acid transporter - permease subunit compare
PP_1699 +0.4 1.6 2-pyrone-4,6-dicarboxylic acid hydrolase compare
PP_2172 +0.4 1.7 conserved exported protein of unknown function compare
PP_2358 +0.4 2.6 putative Type 1 pili subunit CsuA/B protein compare
PP_4734 +0.4 2.8 DNA-binding transcriptional dual regulator, LldR-L-lactate compare
PP_5140 +0.4 1.7 Transcriptional regulator, MerR family compare
PP_2908 +0.4 1.4 DNA-binding transcriptional repressor compare
PP_3495 +0.4 1.9 tRNA (adenine(22)-N(1))-methyltransferase compare
PP_1829 +0.4 1.1 Hydrolase, alpha/beta fold family compare
PP_4365 +0.4 1.7 Flagellar protein FliJ compare
PP_0167 +0.4 3.7 Toxin secretion ATP-binding protein compare
PP_1362 +0.4 1.2 pyruvate kinase II compare
PP_3318 +0.4 0.5 conserved protein of unknown function compare
PP_2341 +0.4 1.0 6-carboxy-5,6,7,8-tetrahydropterin synthase compare
PP_0512 +0.4 1.2 hypothetical protein compare
PP_0181 +0.4 2.1 conserved protein of unknown function compare
PP_3541 +0.4 0.7 Transporter, MgtC family compare
PP_1410 +0.4 0.6 conserved protein of unknown function compare
PP_5182 +0.4 2.1 polyamine:pyruvate transaminase compare
PP_5143 +0.4 1.0 conserved membrane protein of unknown function compare
PP_1664 +0.4 1.9 phosphoribosylglycinamide formyltransferase 1 compare
PP_3512 +0.4 1.1 conserved membrane protein of unknown function compare
PP_5055 +0.4 1.7 Sulfurtransferase compare
PP_1658 +0.4 1.2 conserved protein of unknown function compare
PP_4386 +0.4 2.6 flagellar basal-body rod protein FlgF compare
PP_3643 +0.4 1.1 putative Oxidoreductase compare
PP_5563 +0.4 2.7 conserved membrane protein of unknown function compare
PP_2079 +0.4 1.9 conserved protein of unknown function compare
PP_5258 +0.4 2.0 L-piperidine-6-carboxylate dehydrogenase compare
PP_0580 +0.4 2.0 MaoC domain protein compare
PP_3587 +0.4 1.3 lipid hydroperoxide peroxidase compare
PP_3523 +0.4 2.2 conserved protein of unknown function compare
PP_2748 +0.4 0.8 putative Branched-chain amino acid ABC transporter, ATP-binding protein compare
PP_4579 +0.4 2.5 Transcriptional regulator, LysR family compare
PP_5589 +0.4 1.5 protein of unknown function containing Rhs repeat-associated core domain compare
PP_1275 +0.4 1.6 conserved protein of unknown function compare
PP_4359 +0.4 2.5 Flagellar protein FliL compare
PP_0108 +0.4 1.5 conserved protein of unknown function compare
PP_1381 +0.4 0.6 4-carboxymuconolactone decarboxylase compare
PP_1380 +0.4 1.9 3-oxoadipate enol-lactonase 2 compare
PP_5007 +0.4 0.9 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_3189 +0.4 1.9 cytosine deaminase / isoguanine deaminase compare
PP_3738 +0.4 1.4 putative Transcriptional regulator VanR compare
PP_2074 +0.4 1.3 Transcriptional regulator, LysR family compare
PP_0178 +0.4 2.6 putative efflux pump compare
PP_0643 +0.4 1.1 protein of unknown function compare
PP_4637 +0.4 2.4 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase family protein compare
PP_5496 +0.4 1.6 conserved exported protein of unknown function compare
PP_4391 +0.4 2.0 flagellar basal-body rod protein FlgB compare
PP_4362 +0.4 1.6 conserved protein of unknown function compare
PP_2654 +0.4 1.8 putative Glutathione S-transferase compare
PP_0166 +0.4 3.0 HlyD family secretion protein compare
PP_4384 +0.4 2.6 Flagellar L-ring protein compare
PP_1028 +0.4 1.5 Transcriptional regulator, LysR family compare
PP_2299 +0.4 1.4 Trigger factor compare
PP_3388 +0.4 2.2 conserved protein of unknown function compare
PP_1696 +0.4 2.5 putative Membrane protein compare
PP_5546 +0.4 0.8 conserved protein of unknown function compare
PP_3942 +0.4 1.6 maleate isomerase compare
PP_1907 +0.4 1.4 Hydrolase, haloacid dehalogenase-like family compare
PP_2267 +0.4 1.9 putative Phage single-stranded DNA-binding protein compare
PP_2943 +0.4 2.0 putative Cytochrome c551 peroxidase compare
PP_2655 +0.4 1.1 conserved protein of unknown function compare
PP_5485 +0.4 1.3 putative N-acetyltransferase, GNAT domain compare
PP_5423 +0.4 1.1 conserved membrane protein of unknown function compare
PP_1512 +0.4 1.1 conserved protein of unknown function compare
PP_1009 +0.4 1.5 glyceraldehyde-3-phosphate dehydrogenase compare
PP_2652 +0.4 2.1 putative Hydratase/decarboxylase compare
PP_2858 +0.4 1.7 conserved exported protein of unknown function compare
PP_5295 +0.4 0.5 conserved protein of unknown function compare
PP_2203 +0.4 0.7 conserved protein of unknown function compare
PP_2857 +0.4 0.6 conserved exported protein of unknown function compare
PP_1298 +0.4 2.4 putative amino acid ABC transporter - permease subunit compare
PP_0168 +0.4 3.3 putative surface adhesion protein compare
PP_0179 +0.4 2.4 putative efflux transporter compare
PP_2220 +0.4 1.5 C4-type zinc finger protein, DksA/TraR family compare
PP_2979 +0.4 2.0 conserved protein of unknown function compare
PP_5628 +0.4 1.2 conserved protein of unknown function compare
PP_4200 +0.4 2.1 conserved exported protein of unknown function compare
PP_3409 +0.4 0.8 putative Cobalamin biosynthesis protein cobE compare
PP_4519 +0.4 2.7 Agglutination protein compare
PP_2560 +0.4 1.8 alkaline protease secretion transporter ATP-binding protein compare
PP_2701 +0.4 1.6 Transcriptional regulator, LysR family compare
PP_1168 +0.3 1.6 D-glucuronate / D-galacturonate TRAP transporter, small permease component (from data) compare
PP_5110 +0.3 0.3 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_0235 +0.3 1.4 Peroxidase compare
PP_1554 +0.3 0.9 conserved protein of unknown function compare
PP_4642 +0.3 0.6 Cyclic diguanosine monophosphate-binding protein compare
PP_2657 +0.3 2.4 phosphate ABC transporter compare
PP_2325 +0.3 2.4 2-dehydropantoate 2-reductase compare
PP_3863 +0.3 1.3 putative Phage tail protein compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source rac-3-Hydroxypentanoic Acid in Pseudomonas putida KT2440

For carbon source rac-3-Hydroxypentanoic Acid across organisms