Experiment set29IT067 for Pseudomonas putida KT2440

Compare to:

D-Glucaric acid carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_1004 +1.3 3.5 conserved protein of unknown function compare
PP_2499 +1.3 2.7 conserved protein of unknown function compare
PP_1655 +1.1 6.7 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_5167 +1.0 3.5 conserved hypothetical protein compare
PP_2889 +1.0 4.3 putative Transmembrane regulator PrtR compare
PP_1774 +0.9 1.4 conserved exported protein of unknown function compare
PP_4171 +0.9 7.7 conserved exported protein of unknown function compare
PP_1623 +0.8 5.7 RNA polymerase, sigma S (sigma 38) factor compare
PP_3903 +0.8 1.8 conserved protein of unknown function compare
PP_0673 +0.8 1.4 conserved protein of unknown function compare
PP_5717 +0.8 1.7 conserved protein of unknown function compare
PP_3043 +0.8 1.9 conserved protein of unknown function compare
PP_0307 +0.8 2.1 conserved exported protein of unknown function compare
PP_1142 +0.8 0.9 conserved protein of unknown function compare
PP_4296 +0.7 1.7 conserved exported protein of unknown function compare
PP_3880 +0.7 1.2 conserved exported protein of unknown function compare
PP_5533 +0.7 1.4 conserved protein of unknown function compare
PP_4373 +0.7 5.6 Transcriptional regulator FleQ compare
PP_0905 +0.7 1.3 conserved exported protein of unknown function compare
PP_1864 +0.7 2.0 conserved protein of unknown function compare
PP_1656 +0.7 4.3 ATP:GTP 3'-pyrophosphotransferase compare
PP_2773 +0.7 1.2 conserved protein of unknown function compare
PP_3916 +0.7 2.6 conserved protein of unknown function compare
PP_5267 +0.7 1.9 putative cytochrome c5 compare
PP_2619 +0.7 2.4 FHA domain protein compare
PP_1855 +0.6 3.4 conserved exported protein of unknown function compare
PP_1113 +0.6 4.1 Pyridoxal-phosphate dependent enzyme family protein compare
PP_5610 +0.6 1.9 protein of unknown function compare
PP_5001 +0.6 1.5 protease HslVU, ATPase component compare
PP_4797 +0.6 1.5 conserved protein of unknown function compare
PP_4503 +0.6 1.6 DNA-binding response regulator compare
PP_5705 +0.6 0.9 protein of unknown function compare
PP_3318 +0.6 0.7 conserved protein of unknown function compare
PP_1562 +0.6 1.7 putative Phage terminase, small subunit compare
PP_5008 +0.6 0.6 Poly granule-associated protein compare
PP_1397 +0.6 2.0 conserved protein of unknown function compare
PP_1026 +0.6 2.7 Peptidase, M23/M37 family compare
PP_5053 +0.6 3.2 Protein-export protein SecB compare
PP_4814 +0.5 1.3 ATP-dependent protease La domain protein compare
PP_5473 +0.5 2.2 putative transcriptional regulator, LuxR family compare
PP_5243 +0.5 2.3 putative hydrolase compare
PP_3447 +0.5 0.8 conserved membrane protein of unknown function compare
PP_4697 +0.5 2.3 poly(A) polymerase compare
PP_3035 +0.5 0.9 conserved protein of unknown function compare
PP_3964 +0.5 2.3 transposase compare
PP_4172 +0.5 2.8 conserved exported protein of unknown function compare
PP_1208 +0.5 0.8 conserved protein of unknown function, SlyX family compare
PP_5000 +0.5 0.9 peptidase component of the ATP-dependent HslVU protease compare
PP_4529 +0.5 1.7 conserved protein of unknown function compare
PP_4631 +0.5 2.5 conserved protein of unknown function compare
PP_0945 +0.5 2.1 conserved protein of unknown function compare
PP_3840 +0.5 0.8 conserved protein of unknown function compare
PP_3481 +0.5 0.8 conserved exported protein of unknown function compare
PP_5039 +0.5 2.0 conserved protein of unknown function compare
PP_0773 +0.5 2.3 OmpA/MotB domain-containing protein compare
PP_1903 +0.5 1.3 putative phosphotyrosine-protein phosphatase compare
PP_5580 +0.5 1.3 protein of unknown function compare
PP_2409 +0.5 1.4 cobalt-zinc-cadmium resistance protein compare
PP_3117 +0.5 2.1 putative protein involved in error-prone processing of DNA lesions compare
PP_5232 +0.5 1.1 conserved protein of unknown function compare
PP_3591 +0.5 1.8 Delta 1-piperideine-2-carboxylate reductase compare
PP_0241 +0.5 1.4 Transporter compare
PP_0874 +0.5 0.8 conserved protein of unknown function compare
PP_1415 +0.5 1.6 putative membrane associated enzyme subunit compare
PP_2718 +0.5 1.9 arsenic resistance transcriptional regulator compare
PP_0125 +0.5 1.8 putative cytochrome c-type protein compare
PP_4316 +0.5 2.3 D-isomer specific 2-hydroxyacid dehydrogenase family protein compare
PP_3378 +0.5 0.8 putative 2-ketogluconokinase compare
PP_5621 +0.5 1.5 protein of unknown function compare
PP_3610 +0.5 1.9 conserved protein of unknown function compare
PP_3874 +0.5 1.2 conserved protein of unknown function compare
PP_3738 +0.5 1.6 putative Transcriptional regulator VanR compare
PP_1892 +0.5 1.1 conserved protein of unknown function compare
PP_2299 +0.5 2.1 Trigger factor compare
PP_5575 +0.5 1.2 conserved protein of unknown function compare
PP_2654 +0.5 1.9 putative Glutathione S-transferase compare
PP_5557 +0.5 1.0 protein of unknown function compare
PP_1632 +0.5 0.9 conserved protein of unknown function compare
PP_2565 +0.5 2.9 putative helicase, UvrD/REP family compare
PP_4365 +0.4 2.3 Flagellar protein FliJ compare
PP_1536 +0.4 1.6 conserved protein of unknown function compare
PP_0585 +0.4 1.7 putative metal-sensitive transcriptional regulator, MerR family compare
PP_0257 +0.4 2.3 protein sulfur transferase compare
PP_0839 +0.4 1.9 tRNA Cm32/Um32 methyltransferase compare
PP_5027 +0.4 0.9 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_1095 +0.4 2.5 putative electron transport complex protein compare
PP_5194 +0.4 2.2 aminomethyltransferase compare
PP_2127 +0.4 1.8 Sensor histidine kinase compare
PP_5505 +0.4 1.4 conserved transmembrane protein of unknown function compare
PP_4816 +0.4 2.0 conserved protein of unknown function compare
PP_4532 +0.4 1.3 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_0167 +0.4 3.7 Toxin secretion ATP-binding protein compare
PP_4687 +0.4 1.8 Hemin import ATP-binding protein HmuV compare
PP_0048 +0.4 0.8 conserved protein of unknown function compare
PP_2880 +0.4 1.8 Transcriptional regulator, TetR family compare
PP_5253 +0.4 1.4 Arylesterase compare
PP_3467 +0.4 2.1 Sigma-54 dependent transcriptional regulator compare
PP_2118 +0.4 1.0 conserved protein of unknown function compare
PP_1828 +0.4 1.1 conserved protein of unknown function compare
PP_0547 +0.4 2.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PP_3926 +0.4 0.8 short-chain dehydrogenase compare
PP_1628 +0.4 1.8 NMN amidohydrolase compare
PP_0168 +0.4 3.7 putative surface adhesion protein compare
PP_3018 +0.4 1.6 conserved protein of unknown function compare
PP_5528 +0.4 1.0 conserved protein of unknown function compare
PP_5667 +0.4 1.4 putative microcin B17-like-processing protein, McbC family compare
PP_5583 +0.4 0.6 conserved protein of unknown function compare
PP_5725 +0.4 1.5 protein of unknown function compare
PP_0166 +0.4 3.3 HlyD family secretion protein compare
PP_2511 +0.4 1.6 conserved protein of unknown function compare
PP_5204 +0.4 0.9 conserved protein of unknown function compare
PP_2625 +0.4 2.1 conserved exported protein of unknown function compare
PP_2331 +0.4 2.0 conserved membrane protein of unknown function compare
PP_3019 +0.4 1.7 Carbon-nitrogen hydrolase family protein compare
PP_4618 +0.4 2.0 conserved protein of unknown function compare
PP_1381 +0.4 0.7 4-carboxymuconolactone decarboxylase compare
PP_5714 +0.4 1.2 conserved protein of unknown function compare
PP_0893 +0.4 0.8 ThiJ/PfpI family protein compare
PP_2559 +0.4 1.5 Metalloprotease secretion protein compare
PP_4519 +0.4 3.1 Agglutination protein compare
PP_4793 +0.4 1.0 conserved protein of unknown function compare
PP_2774 +0.4 2.5 glycine betaine ABC transporter, ATPase/permease fusion protein compare
PP_1324 +0.4 1.3 putative endonuclease distantly related to archaeal Holliday junction resolvase compare
PP_1143 +0.4 1.8 3-hydroxyisobutyrate dehydrogenase family protein compare
PP_5359 +0.4 0.8 CobW/P47K family protein compare
PP_1074 +0.4 1.2 DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate compare
PP_2970 +0.4 1.0 conserved exported protein of unknown function compare
PP_3142 +0.4 2.3 putative Sugar transferase compare
PP_0607 +0.4 1.3 putative Type IV pili biogenesis protein FimT compare
PP_0319 +0.4 0.9 conserved protein of unknown function compare
PP_2309 +0.4 1.0 conserved protein of unknown function compare
PP_2691 +0.4 1.5 conserved protein of unknown function compare
PP_4388 +0.4 3.2 Flagellar hook protein FlgE compare
PP_4207 +0.4 1.5 conserved protein of unknown function compare
PP_2396 +0.4 1.5 conserved exported protein of unknown function compare
PP_1898 +0.4 1.0 MotA/TolQ/ExbB proton channel family protein compare
PP_1976 +0.4 2.0 HlyD family secretion protein compare
PP_1319 +0.4 2.0 Ubiquinol--cytochrome c reductase, cytochrome c1 compare
PP_0781 +0.4 1.7 conserved protein of unknown function compare
PP_5313 +0.4 0.9 DNA-binding protein HU-alpha compare
PP_0794 +0.4 1.5 1-phosphofructokinase monomer compare
PP_5200 +0.4 2.6 proline aminopeptidase P II compare
PP_5706 +0.4 0.9 Sec translocation complex - SecG subunit compare
PP_2701 +0.4 1.9 Transcriptional regulator, LysR family compare
PP_5748 +0.4 0.9 cytochrome c heme lyase subunit compare
PP_4774 +0.4 2.2 divalent cation efflux transporter compare
PP_3803 +0.4 1.6 putative Cation ABC transporter, permease protein compare
PP_1978 +0.4 2.1 Transcriptional regulator, TetR family compare
PP_5083 +0.4 1.0 putative Type IV pili biogenesis protein PilM compare
PP_1552 +0.4 1.6 putative Phage replication protein compare
PP_0542 +0.4 2.1 ethanolamine ammonia-lyase, beta-subunit compare
PP_4847 +0.4 0.5 chaperone modulatory of CbpA co-chaperone protein compare
PP_1739 +0.4 1.6 conserved membrane protein of unknown function compare
PP_1907 +0.4 1.7 Hydrolase, haloacid dehalogenase-like family compare
PP_3625 +0.4 1.6 Transporter, LysE family compare
PP_2397 +0.4 1.6 EF hand domain protein compare
PP_4682 +0.3 1.4 conserved protein of unknown function containing tetratricopeptide repeat domain compare
PP_4925 +0.3 1.1 conserved protein of unknown function compare
PP_3487 +0.3 1.0 conserved exported protein of unknown function compare
PP_4384 +0.3 2.5 Flagellar L-ring protein compare
PP_1190 +0.3 1.5 conserved protein of unknown function compare
PP_3823 +0.3 1.7 Cytochrome c-type protein compare
PP_2074 +0.3 1.5 Transcriptional regulator, LysR family compare
PP_3640 +0.3 1.1 Transcriptional regulator, AraC family compare
PP_2358 +0.3 2.0 putative Type 1 pili subunit CsuA/B protein compare
PP_1833 +0.3 1.0 conserved protein of unknown function compare
PP_1736 +0.3 1.4 conserved protein of unknown function compare
PP_3938 +0.3 0.9 conserved protein of unknown function compare
PP_2712 +0.3 1.6 conserved exported protein of unknown function compare
PP_3810 +0.3 1.2 conserved protein of unknown function compare
PP_3277 +0.3 1.3 ring 1,2-phenylacetyl-CoA epoxidase regulatory subunit compare
PP_2333 +0.3 1.1 GntR family transcriptional regulator compare
PP_5023 +0.3 2.3 Amino acid ABC transporter, permease protein compare
PP_2666 +0.3 2.1 conserved exported protein of unknown function compare
PP_2754 +0.3 2.0 putative OprD family outer membrane porin compare
PP_5730 +0.3 1.1 conserved protein of unknown function compare
PP_1661 +0.3 2.3 putative Dehydrogenase subunit compare
PP_0495 +0.3 1.6 type 1 L-asparaginase compare
PP_5537 +0.3 1.2 conserved membrane protein of unknown function compare
PP_3235 +0.3 2.0 conserved protein of unknown function compare
PP_1272 +0.3 2.2 putative Multidrug efflux MFS membrane fusion protein compare
PP_3451 +0.3 1.8 conserved exported protein of unknown function compare
PP_4577 +0.3 1.7 UPF0271 protein PP_4577 compare
PP_1535 +0.3 1.3 putative Methyltransferase compare
PP_2055 +0.3 1.4 putative isomerase compare
PP_4556 +0.3 0.8 conserved protein of unknown function compare
PP_1265 +0.3 1.4 conserved protein of unknown function compare
PP_1300 +0.3 1.1 putative amino acid ABC transporter - ATP-binding subunit compare
PP_0165 +0.3 2.7 GGDEF domain protein compare
PP_1727 +0.3 2.2 Transcriptional regulator, GntR family compare
PP_4818 +0.3 1.0 ribosomal protein L11 methyltransferase compare
PP_1170 +0.3 1.4 D-glucaro-1,5-lactonase UxuL (from data) compare
PP_2951 +0.3 1.5 Transcriptional regulator, TetR family compare
PP_3621 +0.3 2.0 vanillin dehydrogenase, iorA-like component (from data) compare
PP_0630 +0.3 0.3 DNA gyrase inhibitor YacG compare
PP_0109 +0.3 1.4 conserved membrane protein of unknown function compare
PP_4517 +0.3 1.0 conserved protein of unknown function compare
PP_2911 +0.3 2.2 gamma-aminobutyrate permease compare
PP_0643 +0.3 0.9 protein of unknown function compare
PP_2927 +0.3 1.6 conserved protein of unknown function compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source D-Glucaric acid in Pseudomonas putida KT2440

For carbon source D-Glucaric acid across organisms