Experiment set29IT032 for Pseudomonas putida KT2440

Compare to:

Valerolactone carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_5528 +3.6 2.2 conserved protein of unknown function compare
PP_4171 +3.0 17.0 conserved exported protein of unknown function compare
PP_1650 +2.9 16.8 Sensor protein GacS compare
PP_1656 +2.7 11.7 ATP:GTP 3'-pyrophosphotransferase compare
PP_4099 +2.7 14.0 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1215 +2.7 1.8 Crossover junction endodeoxyribonuclease RuvC compare
PP_2389 +2.5 2.7 conserved protein of unknown function compare
PP_1353 +2.4 1.2 conserved membrane protein of unknown function compare
PP_0574 +2.4 18.9 DNA-binding response regulator, LuxR family compare
PP_5309 +2.2 2.0 oxidative and nitrosative stress transcriptional dual regulator compare
PP_3649 +2.1 1.8 Transcriptional regulator, GntR family compare
PP_0575 +2.1 7.9 conserved membrane protein of unknown function compare
PP_4173 +2.1 11.6 Sensor histidine kinase/response regulator compare
PP_3248 +2.0 2.1 Dyp-type peroxidase family protein compare
PP_4804 +2.0 2.5 RlpA-like lipoprotein compare
PP_0673 +1.9 2.3 conserved protein of unknown function compare
PP_4942 +1.9 2.1 conserved protein of unknown function compare
PP_1783 +1.9 1.7 dTDP-glucose pyrophosphorylase compare
PP_1734 +1.8 2.0 Probable septum site-determining protein MinC compare
PP_5310 +1.8 4.0 junction-specific ATP-dependent DNA helicase compare
PP_4172 +1.8 6.8 conserved exported protein of unknown function compare
PP_1761 +1.8 12.7 diguanylate cyclase with phosphodiesterase domain compare
PP_4693 +1.7 1.7 RNA polymerase-binding transcription factor DksA compare
PP_0393 +1.7 2.7 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_2390 +1.7 9.7 Transcriptional regulator, LysR family compare
PP_1623 +1.7 10.7 RNA polymerase, sigma S (sigma 38) factor compare
PP_5217 +1.7 14.8 Polyphosphate kinase compare
PP_0274 +1.5 2.1 putative transcriptional regulator containing HTH domain compare
PP_0319 +1.5 1.7 conserved protein of unknown function compare
PP_1217 +1.5 2.4 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_2683 +1.5 2.5 putative sensory box histidine kinase/response regulator compare
PP_5053 +1.5 7.9 Protein-export protein SecB compare
PP_1113 +1.4 9.4 Pyridoxal-phosphate dependent enzyme family protein compare
PP_5058 +1.4 7.0 Carboxy-terminal-processing protease compare
PP_4707 +1.4 3.6 OsmY-related protein compare
PP_2280 +1.4 2.6 conserved protein of unknown function compare
PP_1058 +1.4 11.1 conserved protein of unknown function compare
PP_2615 +1.4 1.9 hemolysin-coregulated protein compare
PP_2340 +1.4 3.1 conserved protein of unknown function compare
PP_1994 +1.3 1.7 tRNA pseudouridine (38-40)synthase compare
PP_2044 +1.3 0.8 conserved inner membrane protein of unknown function compare
PP_5358 +1.3 4.8 conserved protein of unknown function compare
PP_1733 +1.3 0.8 membrane ATPase of the MinC-MinD-MinE system compare
PP_3541 +1.3 2.4 Transporter, MgtC family compare
PP_2649 +1.3 3.4 Transcriptional regulator, LysR family compare
PP_1444 +1.2 9.6 quinoprotein glucose dehydrogenase compare
PP_1364 +1.2 6.9 conserved exported protein of unknown function compare
PP_4121 +1.2 1.7 NADH-quinone oxidoreductase subunit C/D compare
PP_2707 +1.2 2.1 putative Exodeoxyribonuclease III compare
PP_3519 +1.2 1.3 putative Lipoprotein compare
PP_4629 +1.2 4.5 Sensory box protein compare
PP_2387 +1.2 2.3 conserved protein of unknown function compare
PP_0725 +1.2 6.9 conserved hypothetical TPR repeat protein compare
PP_4204 +1.2 4.4 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor compare
PP_4129 +1.2 1.6 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_1216 +1.2 0.8 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_0962 +1.2 3.7 toluene-tolerance protein compare
PP_1774 +1.1 1.9 conserved exported protein of unknown function compare
PP_3580 +1.1 2.2 conserved protein of unknown function compare
PP_3938 +1.1 0.7 conserved protein of unknown function compare
PP_1982 +1.1 1.6 small heat shock protein IbpA compare
PP_4373 +1.1 8.0 Transcriptional regulator FleQ compare
PP_2680 +1.1 5.5 aldehyde dehydrogenase compare
PP_0856 +1.1 2.2 conserved lipoprotein of unknown function compare
PP_3582 +1.1 1.4 RND efflux transporter, outer membrane protein compare
PP_1054 +1.1 1.2 Type II secretion pathway protein XcpZ compare
PP_0806 +1.1 9.7 putative Surface adhesion protein compare
PP_1366 +1.1 0.8 Transcriptional regulator MvaT, P16 subunit compare
PP_5295 +1.1 1.0 conserved protein of unknown function compare
PP_1903 +1.1 2.0 putative phosphotyrosine-protein phosphatase compare
PP_4710 +1.1 6.8 tRNA pseudouridine 55 synthase compare
PP_0804 +1.0 6.1 Protein secretion ABC efflux system, permease and ATP-binding protein compare
PP_2472 +1.0 4.5 putative transcriptional regulator, MerR family compare
PP_3341 +1.0 2.7 nickel-responsive regulator compare
PP_5701 +1.0 1.3 conserved protein of unknown function compare
PP_1109 +1.0 8.3 Transcriptional regulator, GntR family compare
PP_2000 +1.0 1.0 amidophosphoribosyl transferase compare
PP_5227 +1.0 2.9 diaminopimelate decarboxylase compare
PP_1385 +1.0 5.0 Probable efflux pump membrane transporter TtgB compare
PP_5456 +1.0 1.5 conserved protein of unknown function compare
PP_0958 +1.0 4.6 phospholipid ABC transporter ATP-binding subunit compare
PP_0919 +1.0 1.8 conserved protein of unknown function compare
PP_1110 +1.0 4.7 serine acetyltransferase compare
PP_5143 +1.0 2.1 conserved membrane protein of unknown function compare
PP_1381 +1.0 1.3 4-carboxymuconolactone decarboxylase compare
PP_3616 +1.0 1.8 conserved membrane protein of unknown function compare
PP_2148 +1.0 6.4 transcription-repair coupling factor compare
PP_4406 +1.0 1.8 conserved protein of unknown function compare
PP_3760 +1.0 3.3 putative methyltransferase compare
PP_4964 +0.9 0.9 D-erythrose 4-phosphate dehydrogenase compare
PP_0805 +0.9 5.7 Outer membrane efflux protein compare
PP_4124 +0.9 0.6 NADH-quinone oxidoreductase subunit G compare
PP_1111 +0.9 4.7 putative Synthetase compare
PP_4769 +0.9 3.2 conserved protein of unknown function compare
PP_3380 +0.9 2.8 2-ketogluconate utilization repressor compare
PP_4902 +0.9 1.2 Oligoribonuclease compare
PP_1548 +0.9 1.5 conserved protein of unknown function compare
PP_0497 +0.9 3.0 Transcriptional regulator, Cro/CI family compare
PP_4880 +0.9 3.0 exoribonuclease R compare
PP_3874 +0.9 2.5 conserved protein of unknown function compare
PP_0757 +0.9 3.3 conserved protein of unknown function compare
PP_1512 +0.9 2.5 conserved protein of unknown function compare
PP_4988 +0.9 3.6 signal transduction histidine kinase CheA/CheY-like receiver compare
PP_2417 +0.9 1.9 putative Iron ABC transporter, permease protein compare
PP_2131 +0.9 2.6 DNA-binding ATPase involved in replication compare
PP_1632 +0.9 1.0 conserved protein of unknown function compare
PP_4375 +0.9 4.4 flagellar chaperone, inhibits premature FliC assembly compare
PP_4069 +0.9 1.2 conserved protein of unknown function compare
PP_1655 +0.9 4.7 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_2759 +0.9 2.4 ribose ABC transporter - ATP-binding subunit compare
PP_5146 +0.9 5.0 RNA pyrophosphohydrolase compare
PP_5303 +0.9 2.3 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_4994 +0.9 4.0 conserved protein of unknown function compare
PP_1386 +0.8 5.6 Probable efflux pump periplasmic linker TtgA compare
PP_5598 +0.8 1.7 conserved protein of unknown function compare
PP_4098 +0.8 1.1 UvrABC system protein C compare
PP_1609 +0.8 1.2 conserved protein of unknown function compare
PP_0123 +0.8 2.7 DNA polymerase I, 5 compare
PP_4546 +0.8 2.4 ATP-dependent helicase HrpA compare
PP_5337 +0.8 2.8 LysR family transcriptional regulator compare
PP_1008 +0.8 2.0 RNA polymerase subunit sigma-24 compare
PP_2580 +0.8 1.6 conserved protein of unknown function compare
PP_4238 +0.8 1.4 conserved protein of unknown function compare
PP_4893 +0.8 4.1 GTPase HflX compare
PP_4317 +0.8 1.4 conserved protein of unknown function compare
PP_2305 +0.8 3.8 conserved protein of unknown function compare
PP_5689 +0.8 2.0 conserved protein of unknown function compare
PP_4916 +0.8 2.2 putative esterase compare
PP_4471 +0.8 1.7 Magnesium transporter compare
PP_2634 +0.8 2.9 putative Cellulose synthase compare
PP_2388 +0.8 1.9 Transporter, LysE family compare
PP_5365 +0.8 5.7 putative fatty acid methyltransferase compare
PP_2074 +0.8 1.7 Transcriptional regulator, LysR family compare
PP_0593 +0.8 1.0 putative ribosome-binding factor compare
PP_0719 +0.8 0.5 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_4396 +0.8 3.3 conserved protein of unknown function compare
PP_1186 +0.8 1.1 two component system DNA-binding transcriptional dual regulator compare
PP_4560 +0.8 1.6 putative Ribonuclease BN compare
PP_4938 +0.8 4.1 putative Glycosyl transferase compare
PP_3861 +0.8 1.6 Phage FluMu protein gp46 compare
PP_3835 +0.8 2.7 Sensory box histidine kinase compare
PP_5667 +0.8 1.6 putative microcin B17-like-processing protein, McbC family compare
PP_2749 +0.8 1.3 putative Branched-chain amino acid ABC transporter, permease protein compare
PP_1788 +0.8 1.3 conserved protein of unknown function compare
PP_3411 +0.8 0.8 conserved protein of unknown function compare
PP_2378 +0.8 1.3 Fe/S biogenesis protein NfuA compare
PP_5154 +0.8 1.7 putative Oxidoreductase, FAD-binding compare
PP_5448 +0.8 1.6 conserved protein of unknown function compare
PP_2883 +0.7 1.4 conserved protein of unknown function compare
PP_2331 +0.7 3.4 conserved membrane protein of unknown function compare
PP_4944 +0.7 1.2 Carbamoyltransferase compare
PP_0643 +0.7 1.3 protein of unknown function compare
PP_5063 +0.7 2.0 betaine aldehyde dehydrogenase, NAD-dependent compare
PP_2560 +0.7 2.5 alkaline protease secretion transporter ATP-binding protein compare
PP_2333 +0.7 2.1 GntR family transcriptional regulator compare
PP_5338 +0.7 1.1 aspartate ammonia-lyase compare
PP_0949 +0.7 2.2 putative ATP-binding protein UPF0042 compare
PP_4569 +0.7 1.5 conserved protein of unknown function compare
PP_5216 +0.7 2.1 exopolyphosphatase compare
PP_5167 +0.7 1.2 conserved hypothetical protein compare
PP_4953 +0.7 1.9 putative oxidoreductase with FAD/NAD(P)-binding domain compare
PP_0150 +0.7 1.6 conserved exported protein of unknown function compare
PP_0355 +0.7 2.7 Response regulator compare
PP_0145 +0.7 3.2 Na+/Pi-cotransporter compare
PP_3052 +0.7 0.8 conserved protein of unknown function compare
PP_2750 +0.7 2.1 putative Branched-chain amino acid ABC transporter, permease protein compare
PP_3451 +0.7 2.6 conserved exported protein of unknown function compare
PP_4722 +0.7 2.6 Transcription elongation factor GreA compare
PP_1036 +0.7 1.7 membrane-bound lytic murein transglycosylase F compare
PP_4296 +0.7 0.7 conserved exported protein of unknown function compare
PP_5243 +0.7 1.2 putative hydrolase compare
PP_0841 +0.7 1.2 DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR compare
PP_5569 +0.7 2.0 protein of unknown function of phage origin compare
PP_3916 +0.7 1.4 conserved protein of unknown function compare
PP_0960 +0.7 2.8 phospholipid ABC transporter binding protein compare
PP_2718 +0.7 1.9 arsenic resistance transcriptional regulator compare
PP_5083 +0.7 1.3 putative Type IV pili biogenesis protein PilM compare
PP_2646 +0.7 2.1 conserved protein of unknown function compare
PP_0803 +0.7 4.2 Protein secretion ABC efflux system, membrane fusion protein compare
PP_1867 +0.7 2.7 conserved protein of unknown function compare
PP_2595 +0.7 2.2 putative ABC transporter, permease/ATP-binding protein compare
PP_1629 +0.7 1.4 Protein RecA compare
PP_2336 +0.7 1.0 aconitate hydratase 1 compare
PP_1322 +0.7 1.1 putative Lipoprotein compare
PP_1898 +0.7 1.5 MotA/TolQ/ExbB proton channel family protein compare
PP_5562 +0.7 2.2 conserved protein of unknown function compare
PP_4215 +0.7 2.6 pyoverdine biosynthesis related protein compare
PP_1112 +0.7 3.7 conserved membrane protein of unknown function compare
PP_3531 +0.7 2.1 conserved exported protein of unknown function compare
PP_0440 +0.7 1.5 Elongation factor Tu-A compare
PP_1696 +0.7 3.4 putative Membrane protein compare
PP_3488 +0.7 1.8 Sco1/SenC family protein compare
PP_2737 +0.7 1.4 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_4100 +0.7 2.2 Transcriptional regulator, Cro/CI family compare
PP_1736 +0.7 1.3 conserved protein of unknown function compare
PP_1755 +0.7 2.4 fumarate hydratase (class 2) compare
PP_2980 +0.7 2.2 conserved protein of unknown function compare
PP_3773 +0.6 0.6 conserved protein of unknown function compare
PP_5711 +0.6 2.0 protein of unknown function compare
PP_3408 +0.6 1.0 cobalt transporter subunit A compare


Specific Phenotypes

For 10 genes in this experiment

For carbon source Valerolactone in Pseudomonas putida KT2440

For carbon source Valerolactone across organisms