Experiment set29IT031 for Pseudomonas putida KT2440

Compare to:

Valerolactone carbon source

200 most detrimental genes:

  gene name fitness t score description  
PP_5528 +3.1 2.1 conserved protein of unknown function compare
PP_4171 +3.1 17.3 conserved exported protein of unknown function compare
PP_3942 +3.1 2.1 maleate isomerase compare
PP_1650 +2.8 16.3 Sensor protein GacS compare
PP_4099 +2.8 15.6 two-componenent system BarA/UvrY - regulatory subunit compare
PP_1656 +2.2 8.6 ATP:GTP 3'-pyrophosphotransferase compare
PP_0630 +2.1 2.0 DNA gyrase inhibitor YacG compare
PP_0574 +2.1 15.4 DNA-binding response regulator, LuxR family compare
PP_4173 +2.0 10.5 Sensor histidine kinase/response regulator compare
PP_3043 +2.0 2.8 conserved protein of unknown function compare
PP_4172 +2.0 7.1 conserved exported protein of unknown function compare
PP_1761 +1.9 13.2 diguanylate cyclase with phosphodiesterase domain compare
PP_5632 +1.9 1.7 enzyme subunit involved in allo-isoleucine metabolism compare
PP_0575 +1.8 5.9 conserved membrane protein of unknown function compare
PP_1113 +1.7 10.7 Pyridoxal-phosphate dependent enzyme family protein compare
PP_5217 +1.7 14.4 Polyphosphate kinase compare
PP_1623 +1.7 9.0 RNA polymerase, sigma S (sigma 38) factor compare
PP_5393 +1.6 1.9 putative metal-binding chaperone compare
PP_4910 +1.6 1.5 conserved protein of unknown function compare
PP_3580 +1.5 2.1 conserved protein of unknown function compare
PP_5456 +1.5 1.1 conserved protein of unknown function compare
PP_5053 +1.5 6.4 Protein-export protein SecB compare
PP_2683 +1.5 2.3 putative sensory box histidine kinase/response regulator compare
PP_1300 +1.4 2.1 putative amino acid ABC transporter - ATP-binding subunit compare
PP_5058 +1.4 6.5 Carboxy-terminal-processing protease compare
PP_2389 +1.4 6.2 conserved protein of unknown function compare
PP_5110 +1.4 2.9 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_5604 +1.4 2.9 putative subtilisin-like serine protease compare
PP_1058 +1.4 11.2 conserved protein of unknown function compare
PP_5146 +1.4 6.6 RNA pyrophosphohydrolase compare
PP_3320 +1.3 4.3 conserved protein of unknown function compare
PP_1353 +1.3 0.7 conserved membrane protein of unknown function compare
PP_2680 +1.3 6.5 aldehyde dehydrogenase compare
PP_t29 +1.3 2.7 tRNA-Ala compare
PP_1410 +1.3 1.4 conserved protein of unknown function compare
PP_3411 +1.3 1.3 conserved protein of unknown function compare
PP_1824 +1.3 2.1 Smr domain protein compare
PP_4271 +1.2 0.9 conserved protein of unknown function compare
PP_5309 +1.2 1.2 oxidative and nitrosative stress transcriptional dual regulator compare
PP_2148 +1.2 8.0 transcription-repair coupling factor compare
PP_5248 +1.2 1.1 putative hydrolase compare
PP_4693 +1.2 2.2 RNA polymerase-binding transcription factor DksA compare
PP_1774 +1.2 1.6 conserved exported protein of unknown function compare
PP_1265 +1.2 2.7 conserved protein of unknown function compare
PP_2390 +1.2 5.2 Transcriptional regulator, LysR family compare
PP_4814 +1.2 2.7 ATP-dependent protease La domain protein compare
PP_4503 +1.2 1.7 DNA-binding response regulator compare
PP_2472 +1.2 4.9 putative transcriptional regulator, MerR family compare
PP_0959 +1.2 2.5 phospholipid ABC transporter compare
PP_1503 +1.2 2.3 conserved protein of unknown function compare
PP_4710 +1.2 8.3 tRNA pseudouridine 55 synthase compare
PP_4419 +1.2 2.4 transposase compare
PP_1215 +1.1 0.6 Crossover junction endodeoxyribonuclease RuvC compare
PP_4893 +1.1 5.4 GTPase HflX compare
PP_3105 +1.1 1.5 conserved membrane protein of unknown function compare
PP_2745 +1.1 1.9 Universal stress protein family compare
PP_2387 +1.1 2.1 conserved protein of unknown function compare
PP_1109 +1.1 8.0 Transcriptional regulator, GntR family compare
PP_4942 +1.1 1.0 conserved protein of unknown function compare
PP_0725 +1.1 5.5 conserved hypothetical TPR repeat protein compare
PP_4051 +1.1 4.4 malto-oligosyltrehalose trehalohydrolase compare
PP_2649 +1.1 3.6 Transcriptional regulator, LysR family compare
PP_2889 +1.1 3.3 putative Transmembrane regulator PrtR compare
PP_2409 +1.1 2.1 cobalt-zinc-cadmium resistance protein compare
PP_1111 +1.1 4.7 putative Synthetase compare
PP_5227 +1.1 2.8 diaminopimelate decarboxylase compare
PP_1943 +1.1 4.0 formyltetrahydrofolate deformylase compare
PP_1609 +1.1 2.0 conserved protein of unknown function compare
PP_3332 +1.0 1.1 putative cytochrome c-type protein compare
PP_0153 +1.0 2.9 hypothetical protein compare
PP_4722 +1.0 4.2 Transcription elongation factor GreA compare
PP_4548 +1.0 1.2 putative Oxidoreductase compare
PP_1444 +1.0 7.3 quinoprotein glucose dehydrogenase compare
PP_3058 +1.0 2.8 conserved protein of unknown function compare
PP_3537 +1.0 2.4 p-hydroxybenzoate hydroxylase compare
PP_5358 +1.0 4.3 conserved protein of unknown function compare
PP_1110 +1.0 3.6 serine acetyltransferase compare
PP_4629 +1.0 3.3 Sensory box protein compare
PP_4835 +1.0 1.8 conserved exported protein of unknown function compare
PP_3649 +1.0 0.6 Transcriptional regulator, GntR family compare
PP_5711 +1.0 2.4 protein of unknown function compare
PP_2269 +1.0 1.7 putative N-acetylmuramoyl-L-alanine amidase compare
PP_0640 +1.0 1.9 conserved protein of unknown function compare
PP_4204 +1.0 2.9 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor compare
PP_5310 +1.0 1.8 junction-specific ATP-dependent DNA helicase compare
PP_1569 +1.0 2.8 conserved protein of unknown function compare
PP_5486 +1.0 1.1 conserved protein of unknown function compare
PP_3904 +1.0 1.8 conserved protein of unknown function compare
PP_4253 +1.0 1.7 cytochrome c oxidase subunit, cbb3-type compare
PP_2457 +1.0 4.3 DNA-binding transcriptional repressor compare
PP_1366 +1.0 0.7 Transcriptional regulator MvaT, P16 subunit compare
PP_4798 +1.0 4.6 putative Membrane-bound lytic murein transglycosylase compare
PP_4406 +0.9 1.9 conserved protein of unknown function compare
PP_3651 +0.9 7.1 Sensor histidine kinase/response regulator compare
PP_2388 +0.9 3.1 Transporter, LysE family compare
PP_1396 +0.9 1.7 conserved protein of unknown function compare
PP_0960 +0.9 3.7 phospholipid ABC transporter binding protein compare
PP_2340 +0.9 1.9 conserved protein of unknown function compare
PP_3376 +0.9 3.7 putative phosphonate dehydrogenase compare
PP_0806 +0.9 8.4 putative Surface adhesion protein compare
PP_2844 +0.9 2.9 Urease subunit beta compare
PP_2525 +0.9 1.7 conserved protein of unknown function compare
PP_2290 +0.9 2.4 conserved protein of unknown function compare
PP_5063 +0.9 2.4 betaine aldehyde dehydrogenase, NAD-dependent compare
PP_2131 +0.9 2.6 DNA-binding ATPase involved in replication compare
PP_4504 +0.9 1.3 conserved exported protein of unknown function compare
PP_1018 +0.9 3.1 mannose/glucose ABC transporter - ATP binding subunit compare
PP_2002 +0.9 3.0 putative enzyme compare
PP_1386 +0.9 6.2 Probable efflux pump periplasmic linker TtgA compare
PP_4684 +0.9 4.0 conserved protein of unknown function with kinase-like domain compare
PP_3803 +0.9 3.2 putative Cation ABC transporter, permease protein compare
PP_4994 +0.9 3.4 conserved protein of unknown function compare
PP_4373 +0.9 5.8 Transcriptional regulator FleQ compare
PP_4100 +0.9 2.8 Transcriptional regulator, Cro/CI family compare
PP_5241 +0.9 2.2 DNA-binding response regulator, LuxR family compare
PP_5083 +0.9 1.4 putative Type IV pili biogenesis protein PilM compare
PP_2737 +0.9 1.8 Oxidoreductase, short-chain dehydrogenase/reductase family compare
PP_2147 +0.9 2.0 conserved exported protein of unknown function compare
PP_0757 +0.9 2.2 conserved protein of unknown function compare
PP_3407 +0.8 2.7 conserved protein of unknown function compare
PP_2459 +0.8 1.3 ribose pyranase compare
PP_1385 +0.8 7.2 Probable efflux pump membrane transporter TtgB compare
PP_1605 +0.8 1.2 Ribonuclease HII compare
PP_4356 +0.8 1.4 Flagellar protein FliO compare
PP_0803 +0.8 3.5 Protein secretion ABC efflux system, membrane fusion protein compare
PP_5529 +0.8 1.5 putative epimerase compare
PP_5008 +0.8 1.1 Poly granule-associated protein compare
PP_4460 +0.8 2.8 Transcriptional regulator, LysR family compare
PP_4136 +0.8 0.9 Transcriptional regulator, LuxR family compare
PP_3312 +0.8 0.9 putative Heat shock protein compare
PP_5423 +0.8 1.3 conserved membrane protein of unknown function compare
PP_2616 +0.8 1.7 conserved protein of unknown function compare
PP_3831 +0.8 2.8 conserved protein of unknown function compare
PP_1364 +0.8 5.0 conserved exported protein of unknown function compare
PP_5243 +0.8 2.3 putative hydrolase compare
PP_1178 +0.8 1.9 conserved protein of unknown function compare
PP_4966 +0.8 0.7 transcriptional regulator of methionine metabolism compare
PP_5194 +0.8 2.5 aminomethyltransferase compare
PP_2747 +0.8 1.7 conserved protein of unknown function compare
PP_4068 +0.8 3.6 Transcriptional regulator, Cro/CI family compare
PP_2274 +0.8 1.9 conserved protein of unknown function compare
PP_2849 +0.8 2.6 urease accessory protein compare
PP_4964 +0.8 0.9 D-erythrose 4-phosphate dehydrogenase compare
PP_3487 +0.8 1.5 conserved exported protein of unknown function compare
PP_1528 +0.8 1.2 conserved protein of unknown function compare
PP_1787 +0.8 2.1 conserved protein of unknown function compare
PP_4818 +0.8 2.0 ribosomal protein L11 methyltransferase compare
PP_1734 +0.8 0.5 Probable septum site-determining protein MinC compare
PP_2331 +0.8 3.3 conserved membrane protein of unknown function compare
PP_2712 +0.8 2.5 conserved exported protein of unknown function compare
PP_3401 +0.8 1.8 conserved protein of unknown function compare
PP_1049 +0.8 2.0 putative protein secretion protein for export compare
PP_3400 +0.8 2.7 alpha-ketoglutarate- and Fe(II)-dependent dioxygenase compare
PP_1655 +0.8 3.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD compare
PP_3481 +0.8 1.0 conserved exported protein of unknown function compare
PP_3835 +0.8 2.6 Sensory box histidine kinase compare
PP_3258 +0.8 1.1 conserved protein of unknown function compare
PP_2738 +0.8 1.4 putative Transcriptional regulator compare
PP_2253 +0.8 1.0 Transcriptional regulator, GntR family compare
PP_2163 +0.8 4.1 VacJ lipoprotein compare
PP_1441 +0.8 1.8 tRNA (cmo5U34)-methyltransferase compare
PP_0145 +0.7 2.5 Na+/Pi-cotransporter compare
PP_5682 +0.7 3.0 conserved protein of unknown function compare
PP_3248 +0.7 0.5 Dyp-type peroxidase family protein compare
PP_0800 +0.7 2.8 conserved protein of unknown function compare
PP_5702 +0.7 2.0 conserved protein of unknown function compare
PP_0805 +0.7 3.8 Outer membrane efflux protein compare
PP_5365 +0.7 5.4 putative fatty acid methyltransferase compare
PP_1127 +0.7 1.5 Carboxylesterase compare
PP_4644 +0.7 2.7 DNA repair enzyme compare
PP_3344 +0.7 2.8 nickel ABC transporter permease subunit compare
PP_3441 +0.7 2.7 conserved protein of unknown function compare
PP_5617 +0.7 1.4 conserved protein of unknown function compare
PP_0401 +0.7 1.7 Ribosomal RNA small subunit methyltransferase A compare
PP_5255 +0.7 1.7 putative hydrolase compare
PP_4593 +0.7 1.1 conserved protein of unknown function compare
PP_0513 +0.7 1.3 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP compare
PP_3532 +0.7 0.9 Transcriptional regulator, AsnC family compare
PP_4618 +0.7 2.3 conserved protein of unknown function compare
PP_2622 +0.7 1.4 conserved protein of unknown function compare
PP_5721 +0.7 3.1 conserved protein of unknown function compare
PP_2526 +0.7 1.4 conserved membrane protein of unknown function compare
PP_4907 +0.7 2.7 Thiosulfate sulfurtransferase compare
PP_3817 +0.7 2.0 Polyamine ABC transporter, ATP-binding protein compare
PP_2715 +0.7 2.0 ArsH protein compare
PP_4949 +0.7 2.3 putative peptidase, TldD/PmbA family compare
PP_1261 +0.7 2.1 2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase compare
PP_3384 +0.7 1.7 gluconate 2-dehydrogenase gamma subunit compare
PP_4804 +0.7 0.5 RlpA-like lipoprotein compare
PP_0396 +0.7 4.6 conserved protein of unknown function compare
PP_3892 +0.7 1.2 conserved protein of unknown function compare
PP_4471 +0.7 1.7 Magnesium transporter compare
PP_1801 +0.7 2.4 Glycosyl transferase WbpY compare
PP_5598 +0.7 1.4 conserved protein of unknown function compare
PP_1128 +0.7 1.2 OmpA family protein compare
PP_4785 +0.7 2.8 conserved exported protein of unknown function compare
PP_2943 +0.7 1.8 putative Cytochrome c551 peroxidase compare
PP_1384 +0.7 4.5 Probable efflux pump outer membrane protein TtgC compare
PP_3798 +0.7 1.3 conserved protein of unknown function compare
PP_5390 +0.7 1.7 conserved hypothetical protein compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source Valerolactone in Pseudomonas putida KT2440

For carbon source Valerolactone across organisms