Experiment set29IT030 for Pseudomonas putida KT2440

Compare to:

5-Hydroxydodecanoate carbon source

200 most important genes:

  gene name fitness t score description  
PP_4724 -7.2 -8.6 Carbamoyl-phosphate synthase small chain compare
PP_4723 -7.0 -17.6 Carbamoyl-phosphate synthase large chain compare
PP_0691 -6.7 -4.6 Glutamate 5-kinase compare
PP_5659 -6.6 -4.6 protein of unknown function compare
PP_4116 -6.0 -7.1 isocitrate lyase compare
PP_0422 -5.8 -4.0 Indole-3-glycerol phosphate synthase compare
PP_1988 -5.6 -7.7 3-isopropylmalate dehydrogenase compare
PP_4678 -5.5 -6.6 Ketol-acid reductoisomerase compare
PP_0967 -5.5 -6.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0356 -5.5 -3.8 malate synthase G compare
PP_1231 -5.5 -3.8 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_0787 -5.5 -3.8 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_1985 -5.4 -3.8 3-isopropylmalate dehydratase large subunit compare
PP_4890 -5.4 -6.5 ATP phosphoribosyltransferase regulatory subunit compare
PP_3511 -5.4 -7.4 Branched-chain-amino-acid aminotransferase compare
PP_0417 -5.4 -11.5 Anthranilate synthase component 1 compare
PP_0368 -5.3 -7.3 putative Acyl-CoA dehydrogenase compare
PP_5098 -5.3 -6.3 methionine biosynthesis protein MetW compare
PP_5185 -5.3 -3.7 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_0966 -5.3 -8.0 Histidinol dehydrogenase compare
PP_0292 -5.3 -3.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_0293 -5.2 -3.6 Imidazole glycerol phosphate synthase subunit HisF compare
PP_2137 -5.2 -3.6 beta-ketoadipyl CoA thiolase, beta component compare
PP_1088 -5.2 -7.9 Argininosuccinate synthase compare
PP_1995 -5.1 -3.6 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_4679 -5.1 -5.0 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_0965 -5.1 -11.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_4680 -5.1 -9.1 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_4909 -5.0 -4.9 phosphoserine phosphatase compare
PP_4364 -4.9 -4.7 putative Anti-sigma F factor antagonist compare
PP_2001 -4.8 -9.0 O-succinylhomoserine sulfhydrylase compare
PP_4817 -4.7 -5.6 MaoC domain protein compare
PP_5095 -4.7 -3.3 pyrroline-5-carboxylate reductase compare
PP_4699 -4.7 -3.2 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_0184 -4.6 -3.2 Argininosuccinate lyase compare
PP_3821 -4.4 -9.8 UTP-glucose-1-phosphate uridylyltransferase compare
PP_5097 -4.3 -11.9 homoserine O-acetyltransferase compare
PP_4700 -4.3 -3.0 pantothenate synthetase compare
PP_0164 -4.3 -5.9 conserved protein of unknown function compare
PP_5128 -4.3 -8.4 Dihydroxy-acid dehydratase compare
PP_5155 -4.3 -7.1 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_4999 -4.2 -2.9 dihydroorotase-like protein compare
PP_2168 -4.1 -9.2 Transaldolase compare
PP_1986 -4.1 -2.8 3-isopropylmalate dehydratase small subunit compare
PP_0289 -4.0 -7.3 Imidazoleglycerol-phosphate dehydratase compare
PP_0421 -4.0 -8.2 Anthranilate phosphoribosyltransferase compare
PP_0290 -4.0 -7.6 Imidazole glycerol phosphate synthase subunit HisH compare
PP_5289 -4.0 -4.7 Acetylglutamate kinase compare
PP_4549 -4.0 -10.5 long-chain-fatty-acid/CoA ligase compare
PP_2327 -3.9 -9.9 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_5203 -3.6 -7.3 5-formyltetrahydrofolate cyclo-ligase compare
PP_0082 -3.6 -2.5 tryptophan synthase alpha chain compare
PP_5015 -3.6 -5.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_5717 -3.4 -2.3 conserved protein of unknown function compare
PP_2371 -3.3 -4.5 Sulphite reductase hemoprotein, beta subunit compare
PP_5104 -3.3 -8.4 thiazole synthase compare
PP_4940 -3.2 -4.4 Putative glycosyltransferase compare
PP_0083 -3.2 -3.1 tryptophan synthase beta chain compare
PP_1142 -3.1 -1.5 conserved protein of unknown function compare
PP_2868 -3.0 -7.8 Transcriptional regulator, Cro/CI family compare
PP_5085 -3.0 -8.3 malic enzyme B compare
PP_2328 -3.0 -2.9 Phosphoadenosine phosphosulfate reductase compare
PP_5014 -2.9 -2.0 Phosphoribosyl-AMP cyclohydrolase compare
PP_2136 -2.9 -3.4 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_1025 -2.9 -8.8 2-isopropylmalate synthase compare
PP_4799 -2.8 -1.9 putative Muramoyltetrapeptide carboxypeptidase compare
PP_3999 -2.7 -5.2 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_0246 -2.6 -2.5 two-component system DNA-binding response transcriptional dual regulator compare
PP_0406 -2.6 -5.7 Nucleotidyltransferase family protein compare
PP_1079 -2.6 -4.2 Ornithine carbamoyltransferase compare
PP_5007 -2.5 -3.8 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_3539 -2.5 -2.8 putative Transcriptional regulator compare
PP_1233 -2.4 -4.0 sulfurtransferase compare
PP_5393 -2.4 -1.6 putative metal-binding chaperone compare
PP_2433 -2.4 -1.8 conserved protein of unknown function compare
PP_4943 -2.3 -1.6 putative Glycosyl transferase compare
PP_5008 -2.3 -2.9 Poly granule-associated protein compare
PP_3105 -2.3 -2.1 conserved membrane protein of unknown function compare
PP_2370 -2.2 -2.1 conserved protein of unknown function compare
PP_4701 -2.2 -1.5 glucose-6-phosphate isomerase compare
PP_1664 -2.2 -4.3 phosphoribosylglycinamide formyltransferase 1 compare
PP_4782 -2.1 -4.1 Phosphomethylpyrimidine kinase compare
PP_0420 -2.1 -5.6 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_4828 -2.0 -1.4 Precorrin-8X methylmutase compare
PP_4829 -2.0 -4.2 putative precorrin-3B synthase compare
PP_0765 -2.0 -14.0 putative adhesin (DUF1302) (from data) compare
PP_4136 -2.0 -1.1 Transcriptional regulator, LuxR family compare
PP_0593 -1.9 -1.6 putative ribosome-binding factor compare
PP_3102 -1.9 -6.0 conserved protein of unknown function compare
PP_0735 -1.9 -1.7 molybdopterin-synthase adenylyltransferase compare
PP_0766 -1.9 -11.6 adhesin-associated sorting protein (DUF1329) (from data) compare
PP_2307 -1.9 -2.5 conserved protein of unknown function compare
PP_4922 -1.8 -10.1 Phosphomethylpyrimidine synthase compare
PP_1623 -1.8 -10.3 RNA polymerase, sigma S (sigma 38) factor compare
PP_4997 -1.8 -2.1 pyrimidine operon regulatory protein/uracil phosphoribosyltransferase compare
PP_5322 -1.8 -6.3 putative metal ion transporter compare
PP_4131 -1.8 -2.1 NADH-quinone oxidoreductase subunit N compare
PP_1198 -1.8 -3.4 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_2436 -1.7 -5.2 Transcriptional regulator, LysR family compare
PP_5347 -1.7 -9.0 pyruvate carboxylase subunit A compare
PP_4874 -1.7 -1.2 50S ribosomal protein L9 compare
PP_3926 -1.7 -1.4 short-chain dehydrogenase compare
PP_4696 -1.7 -4.0 Nitrogen regulation protein NR(I) compare
PP_5346 -1.7 -7.2 pyruvate carboxylase subunit B compare
PP_5110 -1.7 -2.2 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit compare
PP_3603 -1.6 -6.5 Transcriptional regulator, GntR family compare
PP_1041 -1.6 -2.1 twin arginine protein export complex subunit compare
PP_0846 -1.6 -1.9 DnaK-like molecular chaperone specific for IscU compare
PP_1493 -1.6 -4.2 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_0435 -1.5 -11.8 Peptidase, M23/M37 family compare
PP_3312 -1.5 -1.4 putative Heat shock protein compare
PP_2903 -1.5 -1.5 peptidyl-prolyl cis-trans isomerase B (rotamase B) compare
PP_4004 -1.5 -1.5 DNA translocase FtsK compare
PP_0767 -1.5 -7.8 Transcriptional regulator, LuxR family compare
PP_4342 -1.5 -1.0 flagellar synthesis regulator, putative ATPase compare
PP_2324 -1.5 -6.3 tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase compare
PP_1208 -1.5 -2.2 conserved protein of unknown function, SlyX family compare
PP_1384 -1.4 -10.3 Probable efflux pump outer membrane protein TtgC compare
PP_4387 -1.4 -1.8 conserved exported protein of unknown function compare
PP_2375 -1.4 -8.2 cobalamin-dependent methionine synthase compare
PP_3505 -1.4 -1.5 conserved protein of unknown function compare
PP_0002 -1.4 -3.9 probable chromosome partition protein compare
PP_4254 -1.4 -1.9 conserved protein of unknown function compare
PP_4143 -1.4 -2.9 conserved protein of unknown function compare
PP_1351 -1.4 -6.0 putative 2-dehydropantoate 2-reductase compare
PP_1654 -1.4 -1.8 cysteine synthase B compare
PP_4545 -1.3 -4.0 beta-ketodecanoyl-(Acyl-carrier-protein) synthase compare
PP_1348 -1.3 -4.1 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_4120 -1.3 -0.9 NADH-quinone oxidoreductase subunit B compare
PP_0001 -1.3 -1.2 probable chromosome-partitioning protein compare
PP_2027 -1.3 -3.1 conserved exported protein of unknown function compare
PP_5090 -1.3 -2.5 putative cell division protein compare
PP_4546 -1.3 -2.8 ATP-dependent helicase HrpA compare
PP_3506 -1.3 -3.9 Magnesium chelatase, subunit ChII compare
PP_4130 -1.3 -3.3 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_1968 -1.3 -5.5 TetR family transcriptional regulator compare
PP_4362 -1.3 -3.5 conserved protein of unknown function compare
PP_1304 -1.3 -7.0 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase compare
PP_3790 -1.2 -5.9 diaminopimelate epimerase compare
PP_4126 -1.2 -0.8 NADH-quinone oxidoreductase subunit I compare
PP_4977 -1.2 -6.3 5,10-methylenetetrahydrofolate reductase compare
PP_3484 -1.2 -3.3 Response regulator receiver protein compare
PP_0653 -1.2 -1.3 conserved protein of unknown function compare
PP_2883 -1.2 -1.7 conserved protein of unknown function compare
PP_0291 -1.2 -1.7 conserved protein of unknown function compare
PP_2302 -1.2 -2.1 DNA-binding, ATP-dependent protease compare
PP_4122 -1.2 -1.1 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_1322 -1.1 -1.4 putative Lipoprotein compare
PP_1293 -1.1 -1.2 molybdopterin synthase small subunit compare
PP_4058 -1.1 -6.7 1,4-alpha-glucan branching enzyme compare
PP_4789 -1.1 -3.0 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_3474 -1.1 -3.8 putative Curli fiber protein CsgE compare
PP_2031 -1.1 -1.5 conserved protein of unknown function compare
PP_4266 -1.1 -3.5 Adenine phosphoribosyltransferase compare
PP_2899 -1.1 -1.4 conserved exported protein of unknown function compare
PP_4263 -1.1 -2.9 putative membrane-bounded cytochrome biogenesis cycZ-like domain, copper tolerance protein compare
PP_3731 -1.1 -4.7 Transcriptional regulator, TetR family compare
PP_3507 -1.1 -6.7 Aerobic cobaltochelatase subunit CobN compare
PP_2145 -1.1 -5.4 beta-N-acetylglucosaminidase compare
PP_4837 -1.1 -1.8 conserved protein of unknown function compare
PP_5552 -1.0 -2.1 conserved protein of unknown function compare
PP_1303 -1.0 -5.0 Sulfate adenylyltransferase subunit 2 compare
PP_3925 -1.0 -6.6 conserved protein of unknown function compare
PP_5705 -1.0 -1.2 protein of unknown function compare
PP_4917 -1.0 -2.7 3',5'-cyclic-nucleotide phosphodiesterase compare
PP_5035 -1.0 -4.2 Histidine utilization repressor compare
PP_5232 -1.0 -1.4 conserved protein of unknown function compare
PP_1941 -1.0 -3.9 conserved protein of unknown function compare
PP_0065 -1.0 -2.0 NAD-binding component of TrK potassium transporter compare
PP_2253 -1.0 -1.0 Transcriptional regulator, GntR family compare
PP_1385 -1.0 -8.7 Probable efflux pump membrane transporter TtgB compare
PP_1386 -1.0 -5.7 Probable efflux pump periplasmic linker TtgA compare
PP_0276 -1.0 -1.1 Transcriptional regulator, Cro/CI family compare
PP_0126 -1.0 -3.0 Cytochrome c4 compare
PP_5583 -0.9 -1.1 conserved protein of unknown function compare
PP_1054 -0.9 -1.4 Type II secretion pathway protein XcpZ compare
PP_0248 -0.9 -5.6 Probable alpha-L-glutamate ligase compare
PP_0362 -0.9 -6.0 Biotin synthase compare
PP_1766 -0.9 -2.8 methylthioribose-1-phosphate isomerase compare
PP_4005 -0.9 -3.1 Leucyl/phenylalanyl-tRNA--protein transferase compare
PP_4824 -0.9 -2.4 Sensor histidine kinase/response regulator compare
PP_1860 -0.9 -4.0 Organic hydroperoxide resistance transcriptional regulator compare
PP_1128 -0.9 -1.8 OmpA family protein compare
PP_3258 -0.9 -2.1 conserved protein of unknown function compare
PP_0370 -0.9 -6.6 Acyl-CoA dehydrogenase family protein compare
PP_1568 -0.9 -0.9 conserved protein of unknown function compare
PP_4256 -0.9 -3.4 cytochrome c oxidase subunit, cbb3-type compare
PP_4320 -0.9 -3.3 cytochrome c-type biogenesis protein compare
PP_0319 -0.9 -1.3 conserved protein of unknown function compare
PP_5028 -0.9 -1.7 proline iminopeptidase compare
PP_1355 -0.9 -8.1 Muropeptide permease AmpG compare
PP_5557 -0.9 -1.2 protein of unknown function compare
PP_0401 -0.9 -2.1 Ribosomal RNA small subunit methyltransferase A compare
PP_4581 -0.9 -1.3 putative amidotransferase compare
PP_3989 -0.9 -2.6 DNA-cytosine methyltransferase compare
PP_4532 -0.9 -1.8 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_3902 -0.9 -1.1 conserved protein of unknown function compare
PP_4895 -0.9 -1.6 tRNA dimethylallyltransferase compare
PP_3132 -0.9 -5.2 putative Polysaccharide transporter compare
PP_2046 -0.9 -2.5 Transcriptional regulator, LysR family compare


Specific Phenotypes

For 14 genes in this experiment

For carbon source 5-Hydroxydodecanoate in Pseudomonas putida KT2440

For carbon source 5-Hydroxydodecanoate across organisms