Experiment set29IT015 for Pseudomonas putida KT2440

Compare to:

DL-3-Aminoisobutyric acid nitrogen source

200 most important genes:

  gene name fitness t score description  
PP_4723 -7.3 -19.0 Carbamoyl-phosphate synthase large chain compare
PP_4724 -6.7 -11.1 Carbamoyl-phosphate synthase small chain compare
PP_5047 -6.4 -4.5 two-component system sensory histidine kinase/phosphatase GlnL/GlnG compare
PP_0595 -6.3 -7.5 Transcriptional regulator, LysR family compare
PP_0422 -6.3 -4.4 Indole-3-glycerol phosphate synthase compare
PP_5048 -6.3 -7.5 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG compare
PP_0596 -6.0 -8.3 Omega-amino acid--pyruvate aminotransferase compare
PP_0290 -6.0 -4.1 Imidazole glycerol phosphate synthase subunit HisH compare
PP_5075 -5.9 -5.8 glutamate synthase (NADPH) beta subunit compare
PP_0293 -5.8 -4.0 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0292 -5.8 -4.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_1988 -5.7 -9.4 3-isopropylmalate dehydrogenase compare
PP_1985 -5.6 -5.5 3-isopropylmalate dehydratase large subunit compare
PP_5185 -5.6 -5.5 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_5098 -5.6 -7.6 methionine biosynthesis protein MetW compare
PP_5076 -5.5 -15.5 L-glutamate synthase(NADPH) alpha subunit compare
PP_1088 -5.5 -9.2 Argininosuccinate synthase compare
PP_5097 -5.5 -10.5 homoserine O-acetyltransferase compare
PP_5289 -5.4 -3.7 Acetylglutamate kinase compare
PP_0417 -5.4 -15.9 Anthranilate synthase component 1 compare
PP_4890 -5.4 -7.4 ATP phosphoribosyltransferase regulatory subunit compare
PP_4909 -5.3 -6.3 phosphoserine phosphatase compare
PP_1995 -5.3 -6.3 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_2001 -5.3 -9.3 O-succinylhomoserine sulfhydrylase compare
PP_1231 -5.3 -6.3 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_0420 -5.2 -10.0 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_0966 -5.1 -10.4 Histidinol dehydrogenase compare
PP_0787 -5.1 -4.9 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_4678 -5.1 -14.7 Ketol-acid reductoisomerase compare
PP_0965 -5.1 -12.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_0967 -5.1 -11.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_4679 -5.0 -6.0 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_0184 -5.0 -4.8 Argininosuccinate lyase compare
PP_3511 -4.8 -9.1 Branched-chain-amino-acid aminotransferase compare
PP_4999 -4.7 -3.3 dihydroorotase-like protein compare
PP_2168 -4.7 -9.1 Transaldolase compare
PP_4680 -4.7 -12.6 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1986 -4.7 -3.2 3-isopropylmalate dehydratase small subunit compare
PP_0289 -4.6 -8.2 Imidazoleglycerol-phosphate dehydratase compare
PP_4700 -4.5 -4.4 pantothenate synthetase compare
PP_2327 -4.5 -10.0 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_1079 -4.5 -4.3 Ornithine carbamoyltransferase compare
PP_5347 -4.4 -10.9 pyruvate carboxylase subunit A compare
PP_5128 -4.3 -8.9 Dihydroxy-acid dehydratase compare
PP_1589 -4.3 -6.5 uridylyltransferase compare
PP_2371 -4.2 -4.1 Sulphite reductase hemoprotein, beta subunit compare
PP_5015 -4.0 -6.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_0421 -4.0 -7.8 Anthranilate phosphoribosyltransferase compare
PP_0082 -3.9 -3.8 tryptophan synthase alpha chain compare
PP_0083 -3.9 -2.7 tryptophan synthase beta chain compare
PP_0339 -3.9 -6.0 Pyruvate dehydrogenase E1 component compare
PP_5303 -3.7 -4.4 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_5348 -3.7 -10.7 Transcriptional regulator, LysR family compare
PP_5155 -3.7 -4.3 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_5014 -3.5 -2.4 Phosphoribosyl-AMP cyclohydrolase compare
PP_4799 -3.4 -2.4 putative Muramoyltetrapeptide carboxypeptidase compare
PP_2328 -3.4 -4.0 Phosphoadenosine phosphosulfate reductase compare
PP_5346 -3.4 -9.8 pyruvate carboxylase subunit B compare
PP_2337 -3.3 -2.3 aconitate isomerase compare
PP_0735 -3.2 -2.0 molybdopterin-synthase adenylyltransferase compare
PP_4058 -3.2 -12.0 1,4-alpha-glucan branching enzyme compare
PP_4699 -3.1 -6.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_1025 -3.0 -11.2 2-isopropylmalate synthase compare
PP_4364 -3.0 -5.0 putative Anti-sigma F factor antagonist compare
PP_4782 -2.9 -5.6 Phosphomethylpyrimidine kinase compare
PP_2334 -2.9 -7.6 2-methylisocitrate lyase compare
PP_2433 -2.8 -3.4 conserved protein of unknown function compare
PP_2088 -2.7 -4.0 RNA polymerase sigma factor SigX compare
PP_2370 -2.7 -3.4 conserved protein of unknown function compare
PP_0362 -2.6 -12.1 Biotin synthase compare
PP_3999 -2.6 -6.9 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_0691 -2.6 -5.8 Glutamate 5-kinase compare
PP_5104 -2.4 -7.3 thiazole synthase compare
PP_1233 -2.4 -4.7 sulfurtransferase compare
PP_4874 -2.3 -1.6 50S ribosomal protein L9 compare
PP_5095 -2.3 -3.5 pyrroline-5-carboxylate reductase compare
PP_2335 -2.2 -7.8 methylcitrate synthase compare
PP_2217 -2.0 -2.5 enoyl-CoA hydratase compare
PP_5331 -2.0 -3.5 Long-chain acyl-CoA thioester hydrolase compare
PP_0127 -1.9 -6.2 Thiol:disulfide interchange protein compare
PP_2336 -1.9 -1.3 aconitate hydratase 1 compare
PP_0001 -1.8 -1.7 probable chromosome-partitioning protein compare
PP_0848 -1.8 -2.7 donor of Fe2+ and regulator of cysteine desulfurase activity compare
PP_5271 -1.8 -3.7 DNA-binding transcriptional dual regulator, leucine-binding compare
PP_1493 -1.7 -3.6 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_4910 -1.7 -1.1 conserved protein of unknown function compare
PP_0597 -1.7 -9.6 methylmalonate-semialdehyde dehydrogenase compare
PP_4122 -1.6 -1.6 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_3398 -1.6 -1.5 putative Curli fiber surface-exposed nucleator CsgB compare
PP_4126 -1.6 -1.5 NADH-quinone oxidoreductase subunit I compare
PP_5350 -1.6 -3.3 Transcriptional regulator, RpiR family compare
PP_0365 -1.6 -7.3 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PP_1269 -1.6 -1.4 Universal stress protein family compare
PP_5322 -1.5 -6.2 putative metal ion transporter compare
PP_5270 -1.5 -3.1 D-amino-acid:quinone oxidoreductase (deaminating) compare
PP_5217 -1.5 -13.1 Polyphosphate kinase compare
PP_0435 -1.5 -12.8 Peptidase, M23/M37 family compare
PP_4922 -1.5 -8.3 Phosphomethylpyrimidine synthase compare
PP_0363 -1.5 -8.9 8-amino-7-oxononanoate synthase compare
PP_0834 -1.5 -2.6 Sec translocation complex subunit YajC compare
PP_4387 -1.5 -2.7 conserved exported protein of unknown function compare
PP_4789 -1.4 -2.6 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_5000 -1.4 -1.1 peptidase component of the ATP-dependent HslVU protease compare
PP_t10 -1.4 -2.4 tRNA-Pro compare
PP_t12 -1.4 -1.1 tRNA-Thr compare
PP_1428 -1.4 -2.1 Sigma factor AlgU negative regulatory protein compare
PP_1022 -1.4 -3.6 glucose 6-phosphate-1-dehydrogenase compare
PP_3447 -1.4 -1.2 conserved membrane protein of unknown function compare
PP_2414 -1.4 -1.8 conserved exported protein of unknown function compare
PP_4828 -1.4 -1.2 Precorrin-8X methylmutase compare
PP_1362 -1.4 -2.6 pyruvate kinase II compare
PP_4984 -1.4 -6.7 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PP_4131 -1.3 -4.4 NADH-quinone oxidoreductase subunit N compare
PP_5278 -1.3 -3.8 4-guanidinobutyraldehyde dehydrogenase compare
PP_0846 -1.3 -2.3 DnaK-like molecular chaperone specific for IscU compare
PP_0364 -1.3 -6.1 pimeloyl-[acp] methyl ester esterase compare
PP_5233 -1.3 -5.3 ammonium transporter AmtB compare
PP_5583 -1.3 -1.3 conserved protein of unknown function compare
PP_0086 -1.2 -1.1 conserved protein of unknown function compare
PP_5328 -1.2 -4.0 putative phosphate transport system permease protein compare
PP_0411 -1.2 -5.3 Polyamine ABC transporter, ATP-binding protein compare
PP_0949 -1.2 -4.0 putative ATP-binding protein UPF0042 compare
PP_5225 -1.2 -1.5 frataxin compare
PP_0063 -1.2 -2.7 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_1987 -1.2 -2.1 Methlytransferase, UbiE/COQ5 family compare
PP_5528 -1.2 -1.3 conserved protein of unknown function compare
PP_2031 -1.2 -1.8 conserved protein of unknown function compare
PP_1198 -1.2 -2.4 transcriptional regulator, Cro/CI family (higA antitoxin like) compare
PP_5027 -1.2 -1.7 D-tyrosyl-tRNA(Tyr) deacylase compare
PP_4720 -1.2 -1.6 putative RNA binding protein compare
PP_1186 -1.2 -1.7 two component system DNA-binding transcriptional dual regulator compare
PP_0809 -1.2 -6.5 disulfide bond formation protein B compare
PP_1994 -1.2 -1.1 tRNA pseudouridine (38-40)synthase compare
PP_2000 -1.1 -1.1 amidophosphoribosyl transferase compare
PP_4480 -1.1 -5.9 arginine N-succinyltransferase, subunit alpha compare
PP_0914 -1.1 -6.1 GGDEF domain protein compare
PP_1128 -1.1 -2.0 OmpA family protein compare
PP_5035 -1.1 -4.1 Histidine utilization repressor compare
PP_0319 -1.1 -1.3 conserved protein of unknown function compare
PP_2302 -1.1 -2.8 DNA-binding, ATP-dependent protease compare
PP_1348 -1.1 -4.7 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_4591 -1.1 -3.5 Ribonuclease D compare
PP_2999 -1.1 -1.2 Glyoxalase family protein compare
PP_3105 -1.1 -1.8 conserved membrane protein of unknown function compare
PP_0366 -1.0 -3.8 dethiobiotin synthetase compare
PP_4368 -1.0 -4.9 flagellar motor switch protein compare
PP_2773 -1.0 -1.3 conserved protein of unknown function compare
PP_4696 -1.0 -3.5 Nitrogen regulation protein NR(I) compare
PP_0164 -1.0 -5.5 conserved protein of unknown function compare
PP_0414 -1.0 -4.5 Polyamine ABC transporter, permease protein compare
PP_0413 -1.0 -7.3 Polyamine ABC transporter, permease protein compare
PP_3098 -1.0 -1.1 conserved protein of unknown function compare
PP_4830 -1.0 -2.9 precorrin-6Y C(5,15)-methyltransferase compare
PP_0948 -1.0 -1.6 Phosphocarrier protein HPr compare
PP_0291 -1.0 -1.2 conserved protein of unknown function compare
PP_2322 -1.0 -6.7 Major outer membrane lipoprotein compare
PP_5441 -1.0 -2.0 protein of unknown function compare
PP_5114 -1.0 -0.9 putative adenine methyltransferase compare
PP_5748 -1.0 -1.5 cytochrome c heme lyase subunit compare
PP_3824 -1.0 -2.2 conserved exported protein of unknown function compare
PP_0957 -1.0 -1.1 D-arabinose 5-phosphate isomerase compare
PP_4943 -0.9 -1.6 putative Glycosyl transferase compare
PP_1045 -0.9 -1.6 Type II secretion pathway protein XcpP compare
PP_1764 -0.9 -3.9 Phosphoglycolate phosphatase 2 compare
PP_5146 -0.9 -5.4 RNA pyrophosphohydrolase compare
PP_5145 -0.9 -8.2 phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins) compare
PP_0377 -0.9 -1.6 coenzyme PQQ synthesis protein D compare
PP_4223 -0.9 -2.4 diaminobutyrate-2-oxoglutarate transaminase compare
PP_1217 -0.9 -1.2 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_4375 -0.9 -4.9 flagellar chaperone, inhibits premature FliC assembly compare
PP_1654 -0.9 -2.1 cysteine synthase B compare
PP_3790 -0.9 -5.0 diaminopimelate epimerase compare
PP_5327 -0.9 -5.2 putative phosphate ABC transporter, permease subunit compare
PP_2575 -0.9 -1.2 conserved exported protein of unknown function compare
PP_4701 -0.9 -0.8 glucose-6-phosphate isomerase compare
PP_0439 -0.9 -2.9 conserved protein of unknown function compare
PP_2929 -0.9 -4.7 Carboxynorspermidine/carboxyspermidine decarboxylase compare
PP_4358 -0.9 -4.8 flagellar synthesis, switching and energizing component compare
PP_1054 -0.9 -1.6 Type II secretion pathway protein XcpZ compare
PP_2402 -0.8 -1.8 putative Sensor histidine kinase compare
PP_3286 -0.8 -2.9 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) compare
PP_1681 -0.8 -5.8 cobalamin 5'-phosphate synthase / Cobalamin synthase compare
PP_1216 -0.8 -0.8 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_4977 -0.8 -5.7 5,10-methylenetetrahydrofolate reductase compare
PP_3506 -0.8 -3.1 Magnesium chelatase, subunit ChII compare
PP_2324 -0.8 -4.4 tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase compare
PP_4504 -0.8 -0.6 conserved exported protein of unknown function compare
PP_5203 -0.8 -3.0 5-formyltetrahydrofolate cyclo-ligase compare
PP_5198 -0.8 -3.0 conserved protein of unknown function compare
PP_0003 -0.8 -1.9 16S RNA methyltransferase compare
PP_2581 -0.8 -1.2 conserved protein of unknown function compare
PP_4130 -0.8 -2.6 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_1224 -0.8 -2.9 periplasmic subunit of the TolQRA transport system compare
PP_5055 -0.8 -2.0 Sulfurtransferase compare
PP_4396 -0.8 -3.2 conserved protein of unknown function compare
PP_2388 -0.8 -2.5 Transporter, LysE family compare
PP_5571 -0.8 -1.2 conserved protein of unknown function compare
PP_3233 -0.8 -3.1 transcriptional regulator with 4Fe-4S cluster, Crp/Fnr family compare
PP_4262 -0.8 -1.9 Cytochrome oxidase maturation protein, cbb3-type compare
PP_1114 -0.8 -2.8 SEC-C domain protein compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source DL-3-Aminoisobutyric acid in Pseudomonas putida KT2440

For nitrogen source DL-3-Aminoisobutyric acid across organisms