Experiment set28IT030 for Pseudomonas putida KT2440

Compare to:

1,6-Hexanediamine nitrogen source

200 most important genes:

  gene name fitness t score description  
PP_0293 -5.5 -3.8 Imidazole glycerol phosphate synthase subunit HisF compare
PP_5047 -5.2 -10.0 two-component system sensory histidine kinase/phosphatase GlnL/GlnG compare
PP_5289 -5.2 -6.2 Acetylglutamate kinase compare
PP_0290 -5.2 -10.5 Imidazole glycerol phosphate synthase subunit HisH compare
PP_1986 -5.0 -4.9 3-isopropylmalate dehydratase small subunit compare
PP_5048 -4.7 -9.8 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG compare
PP_5076 -4.6 -21.8 L-glutamate synthase(NADPH) alpha subunit compare
PP_4999 -4.6 -3.1 dihydroorotase-like protein compare
PP_1985 -4.5 -7.8 3-isopropylmalate dehydratase large subunit compare
PP_5075 -4.5 -16.1 glutamate synthase (NADPH) beta subunit compare
PP_0966 -4.5 -12.9 Histidinol dehydrogenase compare
PP_1988 -4.4 -11.4 3-isopropylmalate dehydrogenase compare
PP_0184 -4.2 -9.0 Argininosuccinate lyase compare
PP_0082 -4.1 -6.9 tryptophan synthase alpha chain compare
PP_4723 -4.1 -22.6 Carbamoyl-phosphate synthase large chain compare
PP_1088 -4.1 -15.1 Argininosuccinate synthase compare
PP_0967 -4.0 -14.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_2168 -4.0 -12.4 Transaldolase compare
PP_0289 -4.0 -10.0 Imidazoleglycerol-phosphate dehydratase compare
PP_4680 -3.9 -18.0 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5014 -3.9 -4.6 Phosphoribosyl-AMP cyclohydrolase compare
PP_4058 -3.8 -16.1 1,4-alpha-glucan branching enzyme compare
PP_3511 -3.8 -11.3 Branched-chain-amino-acid aminotransferase compare
PP_4679 -3.8 -9.9 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_0292 -3.8 -6.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_0965 -3.7 -7.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_4678 -3.7 -17.2 Ketol-acid reductoisomerase compare
PP_1995 -3.7 -10.8 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_4909 -3.7 -10.1 phosphoserine phosphatase compare
PP_5155 -3.7 -3.6 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_5097 -3.6 -16.9 homoserine O-acetyltransferase compare
PP_4724 -3.5 -11.8 Carbamoyl-phosphate synthase small chain compare
PP_0083 -3.5 -7.1 tryptophan synthase beta chain compare
PP_0420 -3.5 -12.7 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_0417 -3.5 -19.2 Anthranilate synthase component 1 compare
PP_0691 -3.4 -7.9 Glutamate 5-kinase compare
PP_4890 -3.4 -8.5 ATP phosphoribosyltransferase regulatory subunit compare
PP_5185 -3.4 -8.1 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_0422 -3.4 -6.6 Indole-3-glycerol phosphate synthase compare
PP_5179 -3.4 -10.9 spermidine/putrescine ABC transporter - ATP binding subunit compare
PP_5098 -3.3 -9.6 methionine biosynthesis protein MetW compare
PP_1079 -3.2 -8.6 Ornithine carbamoyltransferase compare
PP_5128 -3.2 -8.6 Dihydroxy-acid dehydratase compare
PP_0421 -3.1 -8.1 Anthranilate phosphoribosyltransferase compare
PP_1589 -3.0 -11.0 uridylyltransferase compare
PP_5178 -2.9 -11.5 spermidine/putrescine ABC transporter - inner membrane subunit compare
PP_2001 -2.9 -11.0 O-succinylhomoserine sulfhydrylase compare
PP_2371 -2.8 -7.3 Sulphite reductase hemoprotein, beta subunit compare
PP_5181 -2.8 -14.6 spermidine/putrescine ABC transporter - periplasmic subunit compare
PP_1025 -2.7 -11.4 2-isopropylmalate synthase compare
PP_5015 -2.6 -5.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_5177 -2.6 -8.9 spermidine/putrescine ABC transporter - permease subunit compare
PP_5227 -2.5 -9.2 diaminopimelate decarboxylase compare
PP_4696 -2.4 -7.0 Nitrogen regulation protein NR(I) compare
PP_2328 -2.3 -7.6 Phosphoadenosine phosphosulfate reductase compare
PP_4060 -2.3 -14.5 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase compare
PP_3376 -2.3 -7.9 putative phosphonate dehydrogenase compare
PP_5233 -2.1 -8.8 ammonium transporter AmtB compare
PP_1109 -2.0 -13.0 Transcriptional regulator, GntR family compare
PP_1231 -1.9 -6.4 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_4762 -1.8 -7.9 Acyl-CoA thioesterase II compare
PP_2433 -1.8 -4.4 conserved protein of unknown function compare
PP_3999 -1.7 -6.1 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_0063 -1.7 -4.6 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_1111 -1.7 -6.3 putative Synthetase compare
PP_1110 -1.7 -3.0 serine acetyltransferase compare
PP_5182 -1.7 -5.2 polyamine:pyruvate transaminase compare
PP_0339 -1.7 -6.0 Pyruvate dehydrogenase E1 component compare
PP_1468 -1.6 -2.1 Tyrosine recombinase XerD compare
PP_2370 -1.6 -3.1 conserved protein of unknown function compare
PP_1237 -1.6 -2.8 4-hydroxy-tetrahydrodipicolinate synthase compare
PP_5278 -1.6 -5.3 4-guanidinobutyraldehyde dehydrogenase compare
PP_1022 -1.6 -5.6 glucose 6-phosphate-1-dehydrogenase compare
PP_4799 -1.6 -1.8 putative Muramoyltetrapeptide carboxypeptidase compare
PP_0513 -1.4 -2.6 DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP compare
PP_0787 -1.4 -5.0 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_5114 -1.4 -2.2 putative adenine methyltransferase compare
PP_1654 -1.4 -3.0 cysteine synthase B compare
PP_0719 -1.4 -1.3 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_4004 -1.4 -2.6 DNA translocase FtsK compare
PP_5346 -1.3 -5.7 pyruvate carboxylase subunit B compare
PP_3377 -1.3 -9.5 2-ketogluconate transporter, putative compare
PP_5347 -1.3 -8.1 pyruvate carboxylase subunit A compare
PP_2475 -1.3 -3.6 Transcriptional regulator, TetR family compare
PP_2180 -1.3 -7.7 polyamine:pyruvate transaminase compare
PP_4364 -1.2 -3.9 putative Anti-sigma F factor antagonist compare
PP_5350 -1.2 -4.3 Transcriptional regulator, RpiR family compare
PP_0949 -1.2 -4.4 putative ATP-binding protein UPF0042 compare
PP_4895 -1.1 -2.9 tRNA dimethylallyltransferase compare
PP_3380 -1.1 -4.0 2-ketogluconate utilization repressor compare
PP_3378 -1.1 -1.5 putative 2-ketogluconokinase compare
PP_2177 -1.1 -3.5 putative transcriptional regulator compare
PP_0291 -1.1 -2.2 conserved protein of unknown function compare
PP_0846 -1.1 -1.9 DnaK-like molecular chaperone specific for IscU compare
PP_5216 -1.1 -2.1 exopolyphosphatase compare
PP_3726 -1.1 -1.7 Enoyl-CoA hydratase/isomerase family protein compare
PP_0566 -1.1 -1.9 translation-related factor compare
PP_0406 -1.1 -4.2 Nucleotidyltransferase family protein compare
PP_4937 -1.1 -1.4 toluene tolerance protein compare
PP_1366 -1.1 -1.0 Transcriptional regulator MvaT, P16 subunit compare
PP_2402 -1.1 -2.0 putative Sensor histidine kinase compare
PP_5180 -1.1 -3.0 spermidine/putrescine ABC transporter - periplasmic subunit compare
PP_5045 -1.1 -3.4 tRNA sulfurtransferase compare
PP_5095 -1.0 -1.2 pyrroline-5-carboxylate reductase compare
PP_0833 -1.0 -2.9 queuine tRNA-ribosyltransferase compare
PP_0393 -1.0 -0.7 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase compare
PP_1224 -1.0 -5.5 periplasmic subunit of the TolQRA transport system compare
PP_0735 -1.0 -1.2 molybdopterin-synthase adenylyltransferase compare
PP_5322 -1.0 -4.7 putative metal ion transporter compare
PP_1568 -1.0 -1.6 conserved protein of unknown function compare
PP_2000 -1.0 -1.3 amidophosphoribosyl transferase compare
PP_4961 -1.0 -1.3 putative Lipoprotein compare
PP_4482 -1.0 -4.3 Transcriptional regulator, AraC family compare
PP_1994 -1.0 -1.9 tRNA pseudouridine (38-40)synthase compare
PP_1679 -1.0 -3.6 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_2178 -1.0 -6.0 glutamate-putrescine ligase compare
PP_1216 -1.0 -1.4 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_1783 -1.0 -0.6 dTDP-glucose pyrophosphorylase compare
PP_4695 -1.0 -6.7 Sensory box histidine kinase compare
PP_1217 -1.0 -2.4 Holliday junction ATP-dependent DNA helicase RuvB compare
PP_2088 -0.9 -4.1 RNA polymerase sigma factor SigX compare
PP_5183 -0.9 -2.7 glutamylpolyamine synthetase compare
PP_1293 -0.9 -1.7 molybdopterin synthase small subunit compare
PP_4546 -0.9 -3.3 ATP-dependent helicase HrpA compare
PP_1362 -0.9 -3.0 pyruvate kinase II compare
PP_4789 -0.9 -3.4 heat shock protein, Co2+ and Mg2+ efflux protein compare
PP_3110 -0.9 -2.4 protein of unknown function compare
PP_1493 -0.9 -2.5 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_4126 -0.9 -1.4 NADH-quinone oxidoreductase subunit I compare
PP_4532 -0.9 -2.0 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_5093 -0.9 -0.9 twitching motility protein compare
PP_3102 -0.9 -2.9 conserved protein of unknown function compare
PP_5331 -0.9 -2.3 Long-chain acyl-CoA thioester hydrolase compare
PP_0607 -0.8 -1.9 putative Type IV pili biogenesis protein FimT compare
PP_4910 -0.8 -1.4 conserved protein of unknown function compare
PP_5094 -0.8 -3.0 putative enzyme with PLP binding domain compare
PP_0362 -0.8 -6.4 Biotin synthase compare
PP_4964 -0.8 -1.3 D-erythrose 4-phosphate dehydrogenase compare
PP_3880 -0.8 -1.4 conserved exported protein of unknown function compare
PP_2302 -0.8 -2.6 DNA-binding, ATP-dependent protease compare
PP_3946 -0.8 -1.7 HTH-type transcriptional repressor NicR compare
PP_0832 -0.8 -3.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
PP_4880 -0.8 -4.0 exoribonuclease R compare
PP_4296 -0.8 -1.5 conserved exported protein of unknown function compare
PP_3244 -0.8 -3.9 Magnesium transporter, MgtC family compare
PP_4008 -0.8 -4.1 ATP-dependent serine protease compare
PP_4236 -0.8 -2.9 putative Thiol:disulfide interchange protein dsbE compare
PP_3884 -0.8 -4.0 Phage holin, lambda family compare
PP_2327 -0.8 -5.0 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_1826 -0.8 -2.6 Hydrolase, isochorismatase family compare
PP_4122 -0.8 -0.5 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_0914 -0.8 -4.7 GGDEF domain protein compare
PP_1233 -0.8 -2.8 sulfurtransferase compare
PP_5035 -0.8 -3.8 Histidine utilization repressor compare
PP_4984 -0.8 -5.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PP_5100 -0.8 -2.4 dITP/XTP pyrophosphatase compare
PP_1764 -0.8 -2.7 Phosphoglycolate phosphatase 2 compare
PP_4782 -0.8 -2.7 Phosphomethylpyrimidine kinase compare
PP_2145 -0.8 -3.3 beta-N-acetylglucosaminidase compare
PP_4254 -0.7 -1.7 conserved protein of unknown function compare
PP_5072 -0.7 -5.5 efflux transporter compare
PP_4879 -0.7 -1.8 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB compare
PP_5608 -0.7 -3.8 putative exported protein compare
PP_5507 -0.7 -3.0 protein of unknown function compare
PP_1268 -0.7 -2.2 putative HtrA suppressor protein sohA compare
PP_3833 -0.7 -3.3 Response regulator compare
PP_2322 -0.7 -4.4 Major outer membrane lipoprotein compare
PP_3507 -0.7 -5.5 Aerobic cobaltochelatase subunit CobN compare
PP_0405 -0.7 -6.1 conserved protein of unknown function compare
PP_5104 -0.7 -4.0 thiazole synthase compare
PP_1672 -0.7 -3.7 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase compare
PP_1326 -0.7 -2.5 16S rRNA 2'-O-ribose C1402 methyltransferase compare
PP_5000 -0.7 -1.7 peptidase component of the ATP-dependent HslVU protease compare
PP_4005 -0.7 -2.9 Leucyl/phenylalanyl-tRNA--protein transferase compare
PP_2378 -0.7 -0.9 Fe/S biogenesis protein NfuA compare
PP_5500 -0.7 -2.4 protein of unknown function compare
PP_4793 -0.7 -0.9 conserved protein of unknown function compare
PP_0434 -0.7 -4.6 Anhydro-N-acetylmuramic acid kinase compare
PP_1677 -0.7 -3.0 Adenosyl-cobyric acid synthase compare
PP_2677 -0.7 -2.1 conserved exported protein of unknown function compare
PP_4804 -0.7 -1.6 RlpA-like lipoprotein compare
PP_1355 -0.7 -5.6 Muropeptide permease AmpG compare
PP_1675 -0.7 -4.1 Subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_0366 -0.6 -2.3 dethiobiotin synthetase compare
PP_2568 -0.6 -1.2 Ring-cleaving dioxygenase compare
PP_4009 -0.6 -2.4 ATP-dependent Clp protease adapter protein ClpS compare
PP_3318 -0.6 -1.1 conserved protein of unknown function compare
PP_3647 -0.6 -3.0 putative Oxidoreductase compare
PP_4827 -0.6 -4.6 Precorrin-2 C(20)-methyltransferase compare
PP_5230 -0.6 -1.9 Tyrosine recombinase XerC compare
PP_2029 -0.6 -1.2 von Willebrand factor type A domain protein compare
PP_2764 -0.6 -2.0 FMN reductase (NADPH) compare
PP_5348 -0.6 -3.3 Transcriptional regulator, LysR family compare
PP_4392 -0.6 -3.6 chemotaxis protein methyltransferase compare
PP_4168 -0.6 -2.5 conserved protein of unknown function compare
PP_3580 -0.6 -1.7 conserved protein of unknown function compare
PP_0364 -0.6 -3.6 pimeloyl-[acp] methyl ester esterase compare
PP_0345 -0.6 -1.9 putative Heptose kinase WapP compare
PP_0435 -0.6 -5.1 Peptidase, M23/M37 family compare
PP_4684 -0.6 -3.5 conserved protein of unknown function with kinase-like domain compare


Specific Phenotypes

For 11 genes in this experiment

For nitrogen source 1,6-Hexanediamine in Pseudomonas putida KT2440

For nitrogen source 1,6-Hexanediamine across organisms